Central San Diego Trips (flight + hotel)

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to P 3,118 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Central San Diego

Find the best Central San Diego areas and neighborhoods for the activities you enjoy most. Learn more about Central San Diego
Default Image

Mission Valley

3 out of top 10 points of interest in this area

Known for its stunning beaches and popular shops, there's plenty to explore in Mission Valley. Check out top attractions like Fashion Valley Mall and Snapdragon Stadium, and jump on the metro at Hazard Center Station or Mission Valley Center Station to see more of the city.

Find hotels in Mission Valley

Top hotels in Central San Diego

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
8/10 Very Good! (1,959 reviews)
"A little noisy but bareable."

Reviewed on Aug 13, 2025

Get rates
Handlery Hotel
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is P6,737 per night from Aug 24 to Aug 25
P6,737
P7,743 total
Aug 24 - Aug 25
includes taxes & fees
8.6/10 Excellent! (1,171 reviews)
"Clean, convenient and quiet. The staff was very helpful and the breakfast was excellent. Only downside was there was the parking fee."

Reviewed on Aug 11, 2025

Hampton Inn San Diego/Mission Valley
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is P7,207 per night from Aug 25 to Aug 26
P7,207
P8,284 total
Aug 25 - Aug 26
includes taxes & fees
8.4/10 Very Good! (1,487 reviews)
"Amazing!"

Reviewed on Aug 13, 2025

Sheraton Mission Valley San Diego Hotel
See all 1,493 properties in Central San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

San Diego Zoo featuring landscape views, a pond and zoo animals

San Diego Zoo

One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.

San Diego Zoo
Balboa Park

Balboa Park

One of America’s largest urban green spaces, Balboa Park is an exciting spot packed with art, culture, and a world-renowned zoo.

Balboa Park
San Diego Air and Space Museum showing interior views, military items and aircraft

San Diego Air and Space Museum

From a hot air balloon dating back over two centuries to the Command module used on Apollo 9, let your imagination soar amid an array of flight-related exhibits.

San Diego Air and Space Museum

What to do in Central San Diego

Beachside Moped Rentals

Beachside Moped Rentals

P8,666
per adult
Beachside Moped Rentals
San Diego City Lights Night Tour

San Diego City Lights Night Tour

P2,676
per adult
94% of travellers recommend
San Diego City Lights Night Tour
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

P7,212
per adult
86% of travellers recommend
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway
See all activities in Central San Diego

Frequently asked questions

How much does a Central San Diego vacation package cost?
Handcraft your Central San Diego vacation package from as low as . Pick from any combination of flights, hotels and rental cars to create the getaway you've been dreaming about for ages. Be sure to add on a few activities!
How do I get a cheap travel package to Central San Diego?
If you love getting an amazing deal, bundle your bookings into a Central San Diego vacation package. Whether you're chasing flights, hotels, rental cars or tours, you can browse and book them all in one place. You'll have plenty of choice at your fingertips too. Expedia has over 550 partner airlines and 1,000,000 properties worldwide to take your pick of. Fly with who you prefer, book a room where you like and save precious money — now that's the perfect getaway!
Where should I stay in Central San Diego?
Travelers come from all corners of the globe to see San Diego Zoo and San Diego Convention Center in Central San Diego. Book a room near these top attractions and visit them at your leisure.
What are the top hotels in Central San Diego?
Get your escape off to an excellent start by booking a stay at We Create A Home Away From Home Near Shopping 15 Minutes From Beach. It's one of most popular hotels in Central San Diego. Another top option is Cottage 1 Br/1 Bath, 500 Sft.
How far in advance should I book my Central San Diego vacation?
It's tricky picking the best time for airfares, but we generally suggest the earlier, the better. Plenty of international flights on Expedia become available to compare up to a year in advance. If you're unable to do so, don't stress. Bargain prices occasionally appear just weeks before departure dates.
What does an Expedia Central San Diego travel package include?
Expedia has all you need to organize your Central San Diego escape, but how you structure your package is entirely up to you. Pick from any combination of rental cars, flights and hotels. Searching for a few activities to keep you busy? Once you've made your booking, you can add them on too. No matter your budget, there's a vacation package to match your needs.
What should I know before booking a Central San Diego travel package?
So many places to go, so many things to experience. With a travel package, you'll be able to cross more of them off your list. Bundle your flights, rental cars and hotels and make big savings.
Can I choose my airline with a Central San Diego Expedia vacation package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines globally. Our packages give you the flexibility to take your pick of available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Central San Diego vacation package?
Whether it's your hotel or flight, you can cancel or alter it. Booked your Central San Diego vacation package in the last 24 hours? You may be able to make changes or cancellations at no cost. For bookings made more than 24 hours ago, you may incur a fee from your hotel, airline or car rental company. For more details, browse our Customer Service Portal. We'll help you each step of the way.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.