A large suspension bridge, industrial cranes, and a calm river.

Panama Canal Zone 5 Stars Hotels

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Check availability on Panama Canal Zone 5 Star Hotels

Tonight
Oct 3 - Oct 4
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Oct 4 - Oct 5
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Oct 9 - Oct 11
In two weeks
Oct 16 - Oct 18

Our top choices for Panama Canal Zone 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
United States
Avanel
P8,610
P9,471 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Riu Plaza Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.
A modern interior with a decorative ceiling, a person in a white dress, and a blue-lit wall.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.

2. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
United States
Aysha
P15,849
P17,434 total
includes taxes & fees
Oct 31 - Nov 1
Waldorf Astoria Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.

3. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
United States
Jose
P21,956
P24,151 total
includes taxes & fees
Nov 3 - Nov 4
Sofitel Legend Casco Viejo, Panama City
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
The exterior of the Renaissance Hotel with a modern design, featuring a prominent 'R' logo, a geometric ceiling design, and a well-lit entrance area.
A modern hotel entrance with a prominent 'Renaissance Hotel' sign, a well-lit outdoor area with a wooden structure, and a staircase leading to the upper floors.
An indoor swimming pool with lounge chairs and red chairs, surrounded by lush greenery and a modern interior design.

4. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
United States
Carlos
P7,944
P8,739 total
includes taxes & fees
Oct 10 - Oct 11
Renaissance Panama City Hotel
A poolside area with lounge chairs and a view of the ocean.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A terrace with seating and a view of the ocean.

5. JW Marriott Panama

JW Marriott Panama
San Francisco
United States
Nemanja
P16,964
P18,661 total
includes taxes & fees
Oct 31 - Nov 1
JW Marriott Panama
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A spacious hotel lobby with modern furniture, large windows, and a city view.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.
A modern interior with a central seating area, potted plants, and a staircase.

6. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
United States
Mariah
P11,197
P12,316 total
includes taxes & fees
Oct 11 - Oct 12
Hyatt Regency Panama City
A hotel entrance with a central water feature, seating areas, and potted plants.
The entrance of The Santa Maria with a covered walkway and a view of the interior.
A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.
A pool with a central water feature, surrounded by seating areas and potted plants.

7. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
United States
Shelly-Ann
P14,496
P15,946 total
includes taxes & fees
Oct 31 - Nov 1
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.
A high-rise building with a rooftop pool area, surrounded by other buildings.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.

8. W Panama

W Panama
Bella Vista
United States
Naomi
P14,462
P15,908 total
includes taxes & fees
Nov 2 - Nov 3
W Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A modern bar area with seating and a view of the city.
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.
A modern interior with a spiral staircase, a large window, and a seating area.

9. Hilton Panama

Hilton Panama
Bella Vista
United States
Simon
P15,849
P17,434 total
includes taxes & fees
Nov 2 - Nov 3
Hilton Panama
A hotel with a pool, beach, and palm trees.
A spacious lobby with a modern design, featuring a central seating area with sofas and ottomans, surrounded by large, open spaces and natural light.
A large hotel with multiple towers, a central courtyard with a swimming pool, and surrounding landscaped areas.
A beachfront hotel with a large building, a beach, and a clear sky.

10. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
United States
Anna
P12,892
P14,181 total
includes taxes & fees
Oct 12 - Oct 13
The Westin Playa Bonita Panama
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A cozy outdoor seating area with a wooden bench and white tables, surrounded by lush greenery and potted plants.
A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.
A person performing a yoga pose in a living room with a large window and a sofa.

11. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
United States
Juliet
P13,239
P14,563 total
includes taxes & fees
Oct 4 - Oct 5
Bristol Panama, a Registry Collection Hotel
Lobby
Banquet hall
Outdoor pool
Bar (on property)

12. Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
Bella Vista
United States
Aldo
P7,528
P8,316 total
includes taxes & fees
Nov 2 - Nov 3
Waymore Hotel Spa and Casino
Terrace/patio
Room
Casino
Outdoor pool

13. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
MARVIN
P13,357
P14,753 total
includes taxes & fees
Oct 26 - Oct 27
Megapolis Hotel Panamá
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama Canal Zone.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
P8,757
P10,046 total
Oct 9 - Oct 10
includes taxes & fees
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
P11,897
P13,086 total
Oct 5 - Oct 6
includes taxes & fees
9/10 Wonderful! (1,002 reviews)
Central Hotel Panama Casco Viejo
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Avenida Balboa Panama City
P10,047
P11,052 total
Oct 26 - Oct 27
includes taxes & fees
8.6/10 Excellent! (1,759 reviews)
Megapolis Hotel Panamá
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama Canal Zone

Explore the relaxing area of Panama Canal Zone—natural beauty, golf courses, and popular sights like Albrook Shopping Mall.

See all hotels in Panama Canal Zone
A large suspension bridge, industrial cranes, and a calm river.

Top Panama Canal Zone Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Si"
Otto 1-night trip
Posted 6 hours ago
Hotel Riu Plaza Panama

Find out more about Panama Canal Zone

Stay in Luxury: 5 Star Hotels in Panama Canal Zone

There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Panama Canal Zone trip. You'll join the multitudes of holidaymakers who have made Panama Canal Zone so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Panama Canal Zone and indulge in the finer things in life for a while.

5-Star Hotels in Panama Canal Zone

You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. 

But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Panama Canal Zone are waiting for you to relax after an exciting day.

Make Your Escape

The results are in, and Panama Canal Zone 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Panama Canal Zone! Choose one of our Panama Canal Zone 5-star hotels today and soothe yourself in luxe surroundings at your convenience.

Expedia India is rated 4 stars by Feefo based on 1038 reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Panama Canal Zone?
The amount you pay for a 5-star hotel in Panama Canal Zone depends on things like when you plan to go and the length of your vacation. Our insider tip for bagging an awesome deal? Use our pricing filters to compare all of the available accommodations for your selected dates.
  • Search for the lowest price per night from P10,046
What makes a hotel 5 stars in Panama Canal Zone?
In Panama Canal Zone, a hotel must offer a specific number of upscale features to earn 5 stars. These may include gourmet restaurants, saunas and spas, on-site gyms, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their exceptional standard of service. You'll enjoy things like concierge services, nightly turn-down services and in-room massage. Some may even offer extra touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Panama Canal Zone?
Expedia's filters are the quickest way to narrow down what you're looking for. Check the "All inclusive" and "5-star" boxes to see the most luxurious hotels in Panama Canal Zone where your meals, room, entertainment and activities are included in the price. At these getaways, your vacation is pure extravagance from the moment you check in.