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Hotels near 21c Museum Hotel

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Oct 4 - Oct 5
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Our top choices for 21c Museum Hotel hotels

A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.
A spacious dining area with a chandelier, a fireplace, and a view of greenery outside.
A covered outdoor seating area with wicker furniture and a wooden railing.
A building entrance with a dark door, a large number '1332' above it, and two large potted ferns on either side.

1. Louisville Bourbon Inn

Louisville Bourbon Inn
Old Louisville, 2.8 km from 21c Museum Hotel
United States
Roy
P17,452
P20,257 total
includes taxes & fees
Oct 6 - Oct 7
Louisville Bourbon Inn
A wooden staircase with a balustrade leading to a landing.
A dining area with brick walls, wooden shelves, and tables set for a meal.
A bedroom with a bed, a dresser, a television, and a desk with a lamp.
A two-story brick building with a white porch and a sign reading "Hotel".

2. Market Street Inn

Market Street Inn
2.1 km from 21c Museum Hotel
United States
Holly
P12,236
P13,827 total
includes taxes & fees
Oct 12 - Oct 13
Market Street Inn
A grand lobby with ornate columns, plush seating, and a chandelier.
A grand lobby with ornate ceiling, multiple seating areas, and a staircase.
A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.
A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

3. The Brown Hotel

The Brown Hotel
Downtown Louisville, 1.2 km from 21c Museum Hotel
United States
Meghan
P8,398
P9,880 total
includes taxes & fees
Oct 25 - Oct 26
The Brown Hotel
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
An outdoor patio with red furniture, including a table and chairs, and two red umbrellas providing shade.
A room with a red velvet sofa, a blue armchair, and a small round table with books.
A room with a large mirror, a wooden dresser, a red patterned rug, and a door with a wreath.

4. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
Old Louisville, 2.8 km from 21c Museum Hotel
United States
Casey
P11,394
P13,226 total
includes taxes & fees
Oct 6 - Oct 7
DuPont Mansion Bed & Breakfast
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.
A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.
A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.

5. Stellar Suites

Stellar Suites
East Market District, 2.2 km from 21c Museum Hotel
United States
Kevin
P6,150
P10,406 total
includes taxes & fees
Oct 6 - Oct 7
Stellar Suites
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.
A bar with shelves of liquor bottles and a bartender preparing drinks.

6. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville, 0.8 km from 21c Museum Hotel
United States
Anthony
P14,807
P17,422 total
includes taxes & fees
Oct 29 - Oct 30
Hotel Distil, Autograph Collection
A modern bar area with a circular bar, multiple seating options, and a large screen.
A modern interior with a central wooden table, refrigerated beverage dispensers, and shelves stocked with snacks and condiments.
A modern lobby with a fireplace, seating area, and a reception desk.
A modern living room with a sectional sofa, a small table, and a floor lamp. Large windows offer a view of a cityscape and a building with glass windows.

7. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
Downtown Louisville, 1.2 km from 21c Museum Hotel
United States
William
P6,443
P7,581 total
includes taxes & fees
Oct 25 - Oct 26
Cambria Hotel Louisville Downtown-Whiskey Row
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A modern restaurant interior with a staircase, round tables, and a brick wall.
A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".
A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.

8. The Grady

The Grady
Downtown Louisville, 0.1 km from 21c Museum Hotel
United States
Bruce
P10,931
P12,861 total
includes taxes & fees
Oct 11 - Oct 12
The Grady
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
A spacious lobby with a large seating area, a chandelier, and a patterned rug.
A modern hotel with multiple floors, large windows, and a prominent sign for Homewood Suites.
A spacious hotel lobby with a central seating area, stone accent walls, and a chandelier.

9. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
Downtown Louisville, 0.1 km from 21c Museum Hotel
United States
Kelly
P7,437
P8,751 total
includes taxes & fees
Oct 25 - Oct 26
Homewood Suites by Hilton Louisville Downtown, KY
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A steam fountain in a brick alleyway.
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.

10. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville, < 0.1 km from 21c Museum Hotel
United States
Matt
P10,580
P12,761 total
includes taxes & fees
Oct 25 - Oct 26
21c Museum Hotel Louisville
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.
A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.
A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville, 0.8 km from 21c Museum Hotel
United States
Cameron
P11,233
P13,217 total
includes taxes & fees
Oct 11 - Oct 12
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.
A modern hotel lobby with a reception desk, seating area, and a large abstract ceiling artwork.
A modern hotel room with a large bed, a desk with a chair, a flat-screen TV, and a large window offering a city view.
A modern hotel lobby with a brick wall, grey sofas, a coffee table, and a large TV screen displaying "TEMPO by Hilton".

12. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
Phoenix Hill, 2 km from 21c Museum Hotel
United States
Addison
P7,643
P8,992 total
includes taxes & fees
Oct 18 - Oct 19
Tempo By Hilton Louisville Downtown Nulu
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.
A lobby with a marble floor, a reception desk, and a large chandelier.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

13. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville, 0.8 km from 21c Museum Hotel
United States
Samantha
P15,888
P18,694 total
includes taxes & fees
Oct 30 - Oct 31
Omni Louisville Hotel
An outdoor seating area with wicker furniture and a fire pit.
A modern hotel lobby with a large central table, multiple seating areas, and large windows offering city views.
A modern living room with a sofa, armchairs, a coffee table, and a TV.
A modern lounge area with seating, tables, and a view of the city through large windows.

14. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
Downtown Louisville, 0.3 km from 21c Museum Hotel
United States
Derek
P6,881
P8,096 total
includes taxes & fees
Oct 25 - Oct 26
Towneplace Suites By Marriott Louisville Downtown
An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.
A modern bar area with sofas, tables, and a bar stocked with bottles.
A modern lounge area with a pool table, comfortable seating, a fireplace, and a brick accent wall.
A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

15. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
Downtown Louisville, 0.9 km from 21c Museum Hotel
United States
Dolores
P9,028
P10,622 total
includes taxes & fees
Oct 25 - Oct 26
Aloft by Marriott Louisville Downtown
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A bedroom with a bed, a chair, a TV, and a window with curtains.
A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.
A brightly lit grocery store with yellow shelving and a central checkout counter.

16. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
East Market District, 2 km from 21c Museum Hotel
United States
Tyler
P9,508
P11,187 total
includes taxes & fees
Oct 26 - Oct 27
Hotel Genevieve part of JdV by Hyatt
A covered patio with a stone wall, a glass table, and a bench.
A grand room with a fireplace, a staircase, and a chandelier.
A stone house with a balcony, a front door, and a staircase leading to the entrance.
Staircase

17. Central Park Bed & Breakfast

Central Park Bed & Breakfast
Old Louisville, 2.9 km from 21c Museum Hotel
United States
Brittany
P10,682
P12,399 total
includes taxes & fees
Oct 6 - Oct 7
Central Park Bed & Breakfast
A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.
A modern living room with a sofa, ottomans, a coffee table, and a rug.
A modern hotel with a prominent 'Marriott' sign, large windows, and a brick facade.
A modern hotel room with a large bed, a desk with a chair, a TV mounted on the wall, and a window with a city view.

18. Moxy Louisville Downtown

Moxy Louisville Downtown
Downtown Louisville, 0.9 km from 21c Museum Hotel
United States
Bryan
P8,007
P9,421 total
includes taxes & fees
Oct 18 - Oct 19
Moxy Louisville Downtown
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.
A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.
A balcony with a view of a river, a bridge, and a cityscape.

19. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville, 0.5 km from 21c Museum Hotel
United States
Saud
P9,079
P10,682 total
includes taxes & fees
Oct 25 - Oct 26
Galt House Hotel Trademark Collection by Wyndham
A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.
A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.
A modern hotel building with a prominent AC Hotel NULU sign, multiple floors, and a well-lit entrance.
A modern interior with a central seating area, a television screen, and a wooden partition with various items displayed.

20. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
East Market District, 2 km from 21c Museum Hotel
United States
Jen
P8,951
P10,532 total
includes taxes & fees
Oct 25 - Oct 26
AC Hotel Louisville Downtown
View all properties

Compare popular hotels close to 21c Museum Hotel

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.
Louisville Bourbon Inn
10.0
Exceptional
25 reviews
View
A wooden staircase with a balustrade leading to a landing.
Market Street Inn
9.8
Exceptional
125 reviews
View
A grand lobby with ornate columns, plush seating, and a chandelier.
The Brown Hotel
9.4
Exceptional
1,337 reviews
View
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
DuPont Mansion Bed & Breakfast
9.6
Exceptional
147 reviews
View
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
Stellar Suites
9.4
Exceptional
155 reviews
View

Top 21c Museum Hotel Hotel Reviews

Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown

10/10 Excellent
"Great customer service! Staff extremely friendly and helpful! Comfortable room. Great location!"
Maureen 1-night trip
Posted 1 hour ago
Aloft by Marriott Louisville Downtown
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent
"The staff was extremely helpful. The hotel and room were spotless. It was a very convenient location."
Teresa 3-night trip
Posted 3 hours ago
Galt House Hotel Trademark Collection by Wyndham
Omni Louisville Hotel

Omni Louisville Hotel

8/10 Good
"I would love to give the omni 5 stars but our bed was horrible. Everything else about the hotel was wonderful especially the water pressure in the shower. We had a nice time."
Chad 4-night trip
Posted 4 hours ago
Omni Louisville Hotel
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

10/10 Excellent
"Excellent stay"
Frances 5-night trip
Posted 4 hours ago
Embassy Suites Louisville Downtown
The Grady

The Grady

10/10 Excellent
"Beautiful hotel. Very clean with friendly staff and within walking distance to tons of bars and restaurants"
Karlie 1-night trip
Posted 10 hours ago
The Grady
Econo Lodge Louisville Downtown

Econo Lodge Louisville Downtown

8/10 Good
"Bed was very comfortable, room was clean"
Raymond 1-night trip
Posted 10 hours ago
Econo Lodge Louisville Downtown
Hyatt Regency Louisville

Hyatt Regency Louisville

10/10 Excellent
"Gorgeous atrium style hotel just steps away from convention center. Lots to do and see near hotel."
Victoria 1-night trip
Posted 3 days ago
Hyatt Regency Louisville
Louisville Marriott Downtown

Louisville Marriott Downtown

8/10 Good
"Didn’t like the many homeless people right outside on the sidewalk."
Paul 3-night trip
Posted 3 days ago
Louisville Marriott Downtown
The Reserve on Main

The Reserve on Main

10/10 Excellent
"All good."
Jason 2-night trip
Posted 6 days ago
The Reserve on Main

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A historic building with ornate architecture, including columns and decorative moldings.

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Kentucky Center for the Performing Arts

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A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)
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Evan Williams Bourbon Experience

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SAR Genealogical Research Library: NSSAR Library

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Frequently asked questions

What's the area like around 21c Museum Hotel?
21c Museum Hotel is located in a family-friendly area of Louisville known for its beautiful river views and great live music scene. If you're looking for a convenient place to stay, check out the 292 hotels and other accommodations you'll find within a mile.
What's the best place to stay near 21c Museum Hotel?
Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.
How many hotels will I find close to 21c Museum Hotel?
Expedia has 292 hotels and other accommodations within a mile from 21c Museum Hotel.
If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals near 21c Museum Hotel.
What can I see and do near 21c Museum Hotel?
You might want to spend some time browsing the exhibits at Muhammad Ali Center, Louisville Slugger Museum, or Frazier International History Museum. Explore landmarks like Belle of Louisville, Whiskey Row, and Big Four Bridge. You can watch performances at Louisville Palace, Derby Dinner Playhouse, and Headliners Music Hall if you're interested in local theater.