Top 10 Hotels Near 21c Museum Hotel in Louisville for 2026

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Our top choices for 21c Museum Hotel hotels

A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.

A living room with a sofa, armchair, coffee table, fireplace, and large windows.

A spacious dining area with a chandelier, a fireplace, and a view of greenery outside.

A covered outdoor seating area with wicker furniture and a wooden railing.

1. Louisville Bourbon Inn

Old Louisville, 2.8 km from 21c Museum Hotel

Roy

P17,248

P20,020 total

includes taxes & fees

Aug 24 - Aug 25

A wooden staircase with a balustrade leading to a landing.

A dining area with brick walls, wooden shelves, and tables set for a meal.

A brick building with a covered porch, columns, and potted plants.

A two-story brick building with a white porch and a sign reading "Hotel".

2. Market Street Inn

2.1 km from 21c Museum Hotel

Anissa

P10,308

P11,648 total

includes taxes & fees

Aug 23 - Aug 24

A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.

A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.

A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.

3. Stellar Suites

East Market District, 2.2 km from 21c Museum Hotel

Brad

P6,220

P10,448 total

includes taxes & fees

Aug 21 - Aug 22

An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.

A bar with shelves of liquor bottles and a bartender preparing drinks.

A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.

An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.

4. Hotel Distil, Autograph Collection

Downtown Louisville, 0.8 km from 21c Museum Hotel

Jasmine

P14,090

P16,578 total

includes taxes & fees

Aug 30 - Aug 31

A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

A living room with a sofa, a fireplace, a staircase, and a chandelier.

A room with a red velvet sofa, a blue armchair, and a small round table with books.

An outdoor patio with red furniture, including a table and chairs, and two red umbrellas providing shade.

5. DuPont Mansion Bed & Breakfast

Old Louisville, 2.8 km from 21c Museum Hotel

Casey

P8,637

P10,026 total

includes taxes & fees

Sep 1 - Sep 2

A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

A spacious lobby with a large seating area, a chandelier, and a patterned rug.

A swimming pool with lounge chairs and a view of the city.

A modern hotel with multiple floors, large windows, and a prominent sign for Homewood Suites.

6. Homewood Suites by Hilton Louisville Downtown, KY

Downtown Louisville, 0.1 km from 21c Museum Hotel

Jon

P7,046

P8,291 total

includes taxes & fees

Sep 7 - Sep 8

A grand lobby with ornate columns, plush seating, and a chandelier.

A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.

A grand lobby with ornate ceiling, large windows, and classic furniture.

7. The Brown Hotel

Downtown Louisville, 1.2 km from 21c Museum Hotel

Anthony

P8,232

P9,685 total

includes taxes & fees

Aug 21 - Aug 22

An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

A modern hotel lobby with a brick wall, grey sofas, a coffee table, and a large TV screen displaying "TEMPO by Hilton".

A modern hotel lobby with a reception desk, seating area, and a large abstract ceiling artwork.

A modern hotel room with a large bed, a desk with a chair, a flat-screen TV, and a large window offering a city view.

8. Tempo By Hilton Louisville Downtown Nulu

Phoenix Hill, 2 km from 21c Museum Hotel

Jennifer

P7,300

P8,589 total

includes taxes & fees

Aug 24 - Aug 25

A classical gold statue in front of a multi-story building with large windows and a brick facade.

A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.

A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

9. 21c Museum Hotel Louisville

Downtown Louisville, < 0.1 km from 21c Museum Hotel

nicolle

P11,066

P13,330 total

includes taxes & fees

Aug 21 - Aug 22

A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

A lobby with a marble floor, a reception desk, and a large chandelier.

A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.

10. Omni Louisville Hotel

Downtown Louisville, 0.8 km from 21c Museum Hotel

Jon-Michael

P9,842

P11,580 total

includes taxes & fees

Aug 23 - Aug 24

A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

A building with a sign reading "THE GRADY" at the entrance.

A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.

A modern restaurant interior with a staircase, round tables, and a brick wall.

11. The Grady

Downtown Louisville, 0.1 km from 21c Museum Hotel

angela

P10,012

P11,780 total

includes taxes & fees

Aug 30 - Aug 31

An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.

A modern hotel room with a large bed, a city view, and a unique headboard design.

A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

12. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Downtown Louisville, 0.8 km from 21c Museum Hotel

Jeffery

P10,088

P11,869 total

includes taxes & fees

Aug 30 - Aug 31

An outdoor seating area with wicker furniture and a fire pit.

A modern hotel lobby with a large central table, multiple seating areas, and large windows offering city views.

An indoor swimming pool with clear water, a diving board, and lounge chairs around the pool area.

A modern lounge area with seating, tables, and a view of the city through large windows.

13. Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.3 km from 21c Museum Hotel

Tina

P5,997

P7,056 total

includes taxes & fees

Sep 6 - Sep 7

A modern bar area with a circular bar, multiple seating options, and a large screen.

A spacious indoor area with a large dining table, multiple chairs, a fireplace, and a kitchen area with a bar.

A modern living room with a sectional sofa, a small table, and a floor lamp. Large windows offer a view of a cityscape and a building with glass windows.

A modern lobby with a fireplace, seating area, and a reception desk.

14. Cambria Hotel Louisville Downtown-Whiskey Row

Downtown Louisville, 1.2 km from 21c Museum Hotel

Riley

P6,380

P7,506 total

includes taxes & fees

Sep 13 - Sep 14

An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

A modern lounge area with a pool table, comfortable seating, a fireplace, and a brick accent wall.

A modern bar area with sofas, tables, and a bar stocked with bottles.

A modern coffee shop interior with a central island, wooden counter, and large windows.

15. Aloft by Marriott Louisville Downtown

Downtown Louisville, 0.9 km from 21c Museum Hotel

Angela

P6,619

P7,788 total

includes taxes & fees

Sep 6 - Sep 7

A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

A modern hotel room with a large bed, a desk with a chair, a TV mounted on the wall, and a window with a city view.

A modern hotel with a prominent 'Marriott' sign, large windows, and a brick facade.

A modern living room with a sofa, ottomans, a coffee table, and a rug.

16. Moxy Louisville Downtown

Downtown Louisville, 0.9 km from 21c Museum Hotel

Zacarias

P5,935

P6,983 total

includes taxes & fees

Sep 6 - Sep 7

A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.

A modern restaurant with high ceilings, large windows, and a mix of round and rectangular tables.

A modern hotel building with a prominent AC Hotel NULU sign, multiple floors, and a well-lit entrance.

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

17. AC Hotel Louisville Downtown

East Market District, 2 km from 21c Museum Hotel

David

P7,519

P8,847 total

includes taxes & fees

Aug 28 - Aug 29

A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.

A bedroom with a bed, a chair, a TV, and a window with curtains.

A yellow coffee shop counter with a menu board above, displaying various coffee and food items.

A brightly lit grocery store with yellow shelving and a central checkout counter.

18. Hotel Genevieve part of JdV by Hyatt

East Market District, 2 km from 21c Museum Hotel

Christina

P8,346

P9,820 total

includes taxes & fees

Aug 27 - Aug 28

A covered patio with a stone wall, a glass table, and a bench.

A garden pathway with a lantern, potted plants, and a white fence.

A grand room with a fireplace, a staircase, and a chandelier.

19. Central Park Bed & Breakfast

Old Louisville, 2.9 km from 21c Museum Hotel

Angie

P8,126

P9,431 total

includes taxes & fees

Aug 23 - Aug 24

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.

A balcony with a view of a river, a bridge, and a cityscape.

A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

20. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.5 km from 21c Museum Hotel

Dina

P8,840

P10,401 total

includes taxes & fees

Sep 2 - Sep 3

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Compare popular hotels close to 21c Museum Hotel

Property	Property class	Guest rating
Louisville Bourbon Inn	10.0 Exceptional 24 reviews	View
Market Street Inn	9.8 Exceptional 123 reviews	View
Stellar Suites	9.6 Exceptional 146 reviews	View
Hotel Distil, Autograph Collection	9.6 Exceptional 493 reviews	View
DuPont Mansion Bed & Breakfast	9.6 Exceptional 145 reviews	View

Top 21c Museum Hotel Hotel Reviews

21c Museum Hotel Louisville

10/10 Excellent

"It’s beautiful and unique; also well situated…."

Hyatt Regency Louisville

10/10 Excellent

"Amazing rooms, comfortable King beds, loved the views from my room, and the replenishment daily of coffee and water. Hotel gym had a great selection of weights, weightlifting, machines, and cardio equipment. I also love that the Starbucks was connected directly to the hotel. We did eat breakfast at the restaurant once, it was just OK. It wasn’t great for the price. Otherwise, the hotel itself was gorgeous and the rooms were quiet."

Omni Louisville Hotel

10/10 Excellent

"Such a excellent service,staff was so helpful!"

The Grady

10/10 Excellent

"We had a wonderful stay and look forward to visiting again."

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent

"Very clean and very convenient location with great views! Staff was very nice."

Holiday Inn Express & Suites Louisville Downtown by IHG

10/10 Excellent

"Staff was very courteous and helpful. Breakfast was good. Parking is right next to hotel."

Homewood Suites by Hilton Louisville Downtown, KY

10/10 Excellent

"This was my favorite hotel I’ve stayed in. The staff were amazing, the pool was nice, the lobby was beautiful, and our room was spacious and clean. The day we were there, they served afternoon snacks and drinks (only on Wednesdays), which was a great touch. I would 100% stay here again!"

Aloft by Marriott Louisville Downtown

8/10 Good

"This hotel is very nice and right in the middle of things. They have a restaurant and bar, but sadly didn't use it for breakfast. The room is nice and modern with a comfortable bed. I would return."

Louisville Marriott Downtown

10/10 Excellent

"Great location and very helpful staff!"

Other attractions near 21c Museum Hotel

A historic building with ornate architecture, including columns and decorative moldings.

Louisville Science Center

7.8/10 (6 reviews)

Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.

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Kentucky Center for the Performing Arts

8.8/10 (49 reviews)

Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.

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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)

One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.

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A wall of wooden baseball bats organized by size and weight.

Louisville Slugger Museum

9.2/10 (2,299 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

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Golden Statue of David

Find out about the history of Louisville when you take a trip to Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your travels in Louisville. Stroll along the area's riverfront or experience its great live music.

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Evan Williams Bourbon Experience

8.6/10 (20 reviews)

You can take time to visit Evan Williams Bourbon Experience during your travels to Louisville. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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SAR Genealogical Research Library: NSSAR Library

You can spend an afternoon browsing the exhibits at SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.

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Frequently asked questions

What's the area like around 21c Museum Hotel?

21c Museum Hotel is located in a family-friendly area of Louisville known for its beautiful river views and great live music scene. If you're looking for a convenient place to stay, check out the 292 hotels and other accommodations you'll find within a mile.

What's the best place to stay near 21c Museum Hotel?

Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Omni Louisville Hotel and Holiday Inn Express & Suites Louisville Downtown by IHG.

How many hotels will I find close to 21c Museum Hotel?

Expedia has 292 hotels and other accommodations within a mile from 21c Museum Hotel.

If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?

Yes! Most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals near 21c Museum Hotel.

What can I see and do near 21c Museum Hotel?

You might want to spend some time browsing the exhibits at Muhammad Ali Center, Louisville Slugger Museum, or Frazier International History Museum. Explore landmarks like Belle of Louisville, Whiskey Row, and Big Four Bridge. You can watch performances at Louisville Palace, Derby Dinner Playhouse, and Headliners Music Hall if you're interested in local theater.

Hotels near 21c Museum Hotel

Change your mind

Treat yourself

Be picky

Check prices for these dates

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Our top choices for 21c Museum Hotel hotels

1. Louisville Bourbon Inn

2. Market Street Inn

3. Stellar Suites

4. Hotel Distil, Autograph Collection

5. DuPont Mansion Bed & Breakfast

6. Homewood Suites by Hilton Louisville Downtown, KY

7. The Brown Hotel

8. Tempo By Hilton Louisville Downtown Nulu

9. 21c Museum Hotel Louisville

10. Omni Louisville Hotel

11. The Grady

12. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

13. Towneplace Suites By Marriott Louisville Downtown

14. Cambria Hotel Louisville Downtown-Whiskey Row

15. Aloft by Marriott Louisville Downtown

16. Moxy Louisville Downtown

17. AC Hotel Louisville Downtown

18. Hotel Genevieve part of JdV by Hyatt

19. Central Park Bed & Breakfast

20. Galt House Hotel Trademark Collection by Wyndham

Compare popular hotels close to 21c Museum Hotel

Top 21c Museum Hotel Hotel Reviews

21c Museum Hotel Louisville

Hyatt Regency Louisville

Omni Louisville Hotel

The Grady

Galt House Hotel Trademark Collection by Wyndham

Holiday Inn Express & Suites Louisville Downtown by IHG

Homewood Suites by Hilton Louisville Downtown, KY

Aloft by Marriott Louisville Downtown

Louisville Marriott Downtown

Other attractions near 21c Museum Hotel

Louisville Science Center

Kentucky Center for the Performing Arts

Muhammad Ali Center

Louisville Slugger Museum

Golden Statue of David

Kentucky Museum of Art and Craft

Evan Williams Bourbon Experience

SAR Genealogical Research Library: NSSAR Library

Frequently asked questions