Cheap flights from Santo Domingo starting at

Popular airlines from Santo Domingo

  • American Airlines

    American Airlines

  • Delta

    Delta

  • JetBlue Airways

    JetBlue Airways

  • Copa

    Copa

  • United

    United

  • Spirit Airlines

    Spirit Airlines

  • Sterling Blue

    Sterling Blue

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Explore a world of travel with Expedia

*Available to Expedia members.