A bench, a bicycle, and a lake surrounded by trees.

Hotels with Spa in Upstate South Carolina, South Carolina

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Check availability on Upstate South Carolina Hotels with Spa

Tonight
Oct 11 - Oct 12
Tomorrow
Oct 12 - Oct 13
Next weekend
Oct 16 - Oct 18
In two weeks
Oct 23 - Oct 25

Our top choices for Upstate South Carolina hotels with a spa

A spa room with two beds, a mural, and a reception desk.
A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.
A modern interior with a stone fireplace, seating areas, and a unique ceiling design.
A modern interior with a fireplace, plush seating, and a stone accent wall.

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
Greenville Downtown
  • Escape to a Tudor retreat with a full-service spa and rooftop garden overlooking the scenic river in Greenville.
P27,641
P31,318 total
includes taxes & fees
Nov 1 - Nov 2
Grand Bohemian Lodge Greenville, Autograph Collection
A modern hotel lobby with a chandelier, wooden shelving, a reception desk, and a view of the outdoors.
A restaurant with a bar area, green upholstered seating, and a view of trees through large windows.
A large, two-story house with a symmetrical facade, large windows, and a central entrance.
A cozy lounge area with leather armchairs, a central table, and a fireplace.

2. Hotel Hartness

Hotel Hartness
Greenville
  • Indulge in rejuvenating treatments at this upscale hotel with six couples spa rooms and scenic hiking trails for a peaceful escape.
P11,313
P14,891 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Hartness
A two-story house with a tiled roof, a stone fire pit, and outdoor seating.
A swimming pool with lounge chairs and a building with balconies.
A reception area with a wooden reception desk, a large abstract painting, and a potted plant.
A spacious room with wooden beams, a large chandelier, and a cozy seating area with orange chairs and a white sofa.

3. Hotel Domestique

Hotel Domestique
Travelers Rest
  • Retreat to this mountain hotel with therapeutic massage treatments, sauna, and seasonal outdoor pool for deep relaxation.
P26,322
P28,954 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Domestique
Exterior
Terrace/patio
Interior
Dining

4. Bed & Breakfast on Tiffany Hill

Bed & Breakfast on Tiffany Hill
Mills River
P16,962
P19,124 total
includes taxes & fees
Nov 8 - Nov 9
Bed & Breakfast on Tiffany Hill
A cozy living room with a fireplace, a sofa, a leather ottoman, and a chandelier.
A bathroom with a white and navy shower curtain, a white bathtub, and a hexagonal tile floor.
A dining room with a wooden table, chairs, and a fireplace.
A modern living room with a sofa, ottoman, and a zebra-patterned rug.

5. Morgan and Wells B&B

Morgan and Wells B&B
Shelby
  • A tranquil bed and breakfast retreat offering couples massages and garden views for a rejuvenating escape.
P9,615
P10,841 total
includes taxes & fees
Oct 12 - Oct 13
Morgan and Wells B&B
A two-story wooden cabin with a balcony, a swimming pool, and a deck area.
A cozy room with a bed, a chair, a tray with snacks and wine, and a view of the outdoors.
A two-story wooden house with a porch, surrounded by dense forest.
A wooden interior with tables and chairs, a fireplace, and a stone wall.

6. Glen-Ella Springs Hotel & Restaurant

Glen-Ella Springs Hotel & Restaurant
Clarkesville
  • Relaxing country retreat with in-room massages and a serene garden setting for a rejuvenating spa experience.
P13,230
P15,132 total
includes taxes & fees
Oct 12 - Oct 13
Glen-Ella Springs Hotel & Restaurant
A hotel room with a bed, a bedside lamp, and a small table with candles.
A stone staircase leading to a house with a stone chimney and a small glass door.
A swimming pool with lounge chairs and umbrellas, surrounded by autumn trees and a lake view.
A spacious dining area with multiple tables and chairs, large windows, and ornate chandeliers.

7. Greystone Inn

Greystone Inn
Lake Toxaway
  • Soak in mountain views at this lakeside retreat with couples' spa treatment rooms, yoga classes, and deep-tissue massages.
P22,050
P26,747 total
includes taxes & fees
Nov 8 - Nov 9
Greystone Inn
A hotel room with two beds, a desk, a chair, a mirror, and a window with curtains.
A bedroom with a bed, a ceiling fan, a bedside table, and a nightstand.
A dining area with checkered flooring, multiple tables and chairs, and a decorative cabinet with various items.
A modern bathroom with a glass shower enclosure, a white toilet, and a sink with a mirror above it.

8. 1898 Waverly Inn

1898 Waverly Inn
Hendersonville
  • Experience spa bliss at this charming B&B with relaxing massage treatment rooms and attentive staff who ensure a rejuvenating stay.
P10,617
P11,970 total
includes taxes & fees
Nov 3 - Nov 4
1898 Waverly Inn
A round table set for four with wicker chairs, a white tablecloth, and a view of a forested area through large windows.
A wooden bridge over a small water feature with a large water wheel in the background.
A bedroom with two beds, wooden headboard panels, and a window with a view.
A bathroom with a shower area, a toilet, and a sink.

9. Sylvan Falls Mill B&B

Sylvan Falls Mill B&B
Rabun Gap
  • Serene mountain retreat offers restorative massages in a garden setting, steps away from Chattahoochee National Forest.
P12,501
P14,816 total
includes taxes & fees
Oct 28 - Oct 29
Sylvan Falls Mill B&B
Spa
Aerial view
Terrace/patio
Yoga

10. The Horse Shoe Farm

The Horse Shoe Farm
Hendersonville
  • Relax in a mountain ranch sanctuary with 5 treatment rooms and outdoor spa areas for nature-inspired healing.
P28,269
P31,874 total
includes taxes & fees
Nov 1 - Nov 2
The Horse Shoe Farm
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Choose what matters most at spa hotels in Upstate South Carolina

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Upstate South Carolina Hotel Reviews

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