Photo by RVLuckyorWhat

Upstate South Carolina Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Jan 6 - Jan 7
Tomorrow
Jan 7 - Jan 8
This weekend
Jan 9 - Jan 11
Next weekend
Jan 16 - Jan 18

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Upstate South Carolina hotels

Lobby lounge
The Abernathy of Clemson

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (560)
"location is amazing! "
United States
colleen
The Abernathy of Clemson
Hallway
The Inn at Patrick Square

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (787)
"Everything was clean staff was courteous and accommodating. "
United States
Stewart
The price is P8,807
P9,776 total
includes taxes & fees
Jan 8 - Jan 9
The Inn at Patrick Square
Premium bedding, individually decorated, desk, laptop workspace
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very Good, (1000)
"Great area behind the hotel to walk my dog!!"
United States
Connie
The price is P6,064
P6,731 total
includes taxes & fees
Jan 13 - Jan 14
Comfort Inn & Suites Clemson - University Area
Cafe
Courtyard Marriott Clemson

Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
Clemson
9.2 out of 10, Wonderful, (525)
"Overall, great stay!"
United States
Lynn
The price is P7,394
P8,208 total
includes taxes & fees
Jan 13 - Jan 14
Courtyard Marriott Clemson
Golf
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.6 out of 10, Exceptional, (961)
"Great place to stay!"
United States
Mindi
The price is P8,807
P9,776 total
includes taxes & fees
Jan 7 - Jan 8
Clemson University's James F. Martin Inn
Free breakfast
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very Good, (1000)
"Clean room and staff were great’"
United States
Audrey
The price is P5,476
P6,079 total
includes taxes & fees
Jan 11 - Jan 12
Best Western Plus Clemson Hotel & Conference Center
Lobby lounge
Inn @ Clemson

Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.0 out of 10, Very Good, (1004)
"Staff and hotel was amazing "
United States
Keren
Inn @ Clemson
Lobby
Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg
3.0 star property
Spartanburg
9.4 out of 10, Exceptional, (442)
"Friendly staff, clean rooms, excellent food! "
United States
Ashley
The price is P7,034
P7,807 total
includes taxes & fees
Jan 25 - Jan 26
Four Points by Sheraton Spartanburg
Bar (on property)
Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg
3.0 star property
Spartanburg
9.4 out of 10, Exceptional, (494)
"Very nice lady at check in"
United States
James
The price is P6,979
P7,747 total
includes taxes & fees
Jan 25 - Jan 26
Hilton Garden Inn Spartanburg
Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe
Days Inn by Wyndham Greenville South/Mauldin

Days Inn by Wyndham Greenville South/Mauldin

Days Inn by Wyndham Greenville South/Mauldin
2.0 star property
Mauldin
7.4 out of 10, Good, (663)
"Staff was friendly, room was clean. Looks like they've done recent renovations. Only issue was noise level between rooms."
United States
Kate
The price is P4,270
P4,698 total
includes taxes & fees
Jan 7 - Jan 8
Days Inn by Wyndham Greenville South/Mauldin
Reception
Hampton Inn Spartanburg-North I-85

Hampton Inn Spartanburg-North I-85

Hampton Inn Spartanburg-North I-85
2.5 star property
Spartanburg
8.6 out of 10, Excellent, (1005)
"Great staff, clean room, good location. Would definitely stay here again!"
United States
Randall
The price is P4,604
P5,111 total
includes taxes & fees
Jan 25 - Jan 26
Hampton Inn Spartanburg-North I-85
Terrace/patio
Spartanburg Marriott

Spartanburg Marriott

Spartanburg Marriott
3.5 star property
Spartanburg
8.6 out of 10, Excellent, (1001)
"Clean, very kind and helpful staff, we had a wonderful and comfortable stay. "
United States
Courtney
The price is P8,511
P9,448 total
includes taxes & fees
Jan 9 - Jan 10
Spartanburg Marriott
Lobby
Best Western Spartanburg Northwest

Best Western Spartanburg Northwest

Best Western Spartanburg Northwest
3.0 star property
Spartanburg
8.2 out of 10, Very Good, (824)
"Great place"
United States
Jamie
The price is P5,225
P5,800 total
includes taxes & fees
Jan 8 - Jan 9
Best Western Spartanburg Northwest
Lobby
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (746)
"Staff was amazing and our room was clean and comfortable. "
United States
Amanda R
The price is P10,580
P11,744 total
includes taxes & fees
Jan 18 - Jan 19
The Shepherd Hotel Downtown Clemson
Lobby sitting area
Woodspring Suites Greenville Airport

Woodspring Suites Greenville Airport

Woodspring Suites Greenville Airport
2.5 star property
Greenville
8.4 out of 10, Very Good, (318)
"everything was perfect "
United States
Makiya
The price is P4,669
P5,136 total
includes taxes & fees
Jan 7 - Jan 8
Woodspring Suites Greenville Airport
Free daily on-the-go breakfast
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
2.5 star property
Spartanburg
9.0 out of 10, Wonderful, (716)
"We loved taking advantage of the breakfast bar. We were visiting for a volleyball tournament and it was a great way for our player to fuel up before heading to the courts!"
United States
Melissa
The price is P5,261
P5,839 total
includes taxes & fees
Jan 11 - Jan 12
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
Free daily full breakfast
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall
2.5 star property
Spartanburg
8.2 out of 10, Very Good, (1006)
"The room was great."
United States
Lacy
The price is P5,532
P6,141 total
includes taxes & fees
Jan 25 - Jan 26
Comfort Suites At WestGate Mall
3 restaurants, breakfast, dinner served; Modern European cuisine
AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg
3.5 star property
Spartanburg
9.2 out of 10, Wonderful, (592)
"The gentleman at the front desk when I checked in made me feel very comfortable. He was so chill. It was a great stay"
United States
robert
The price is P9,398
P10,432 total
includes taxes & fees
Jan 18 - Jan 19
AC Hotel by Marriott Spartanburg
Terrace/patio
Tru by Hilton Spartanburg

Tru by Hilton Spartanburg

Tru by Hilton Spartanburg
2.5 star property
Spartanburg
9.2 out of 10, Wonderful, (834)
"The place was perfect for our, trip"
United States
Ronald
The price is P6,252
P6,940 total
includes taxes & fees
Feb 1 - Feb 2
Tru by Hilton Spartanburg
Interior entrance
SUN AND SAND MOTEL

SUN AND SAND MOTEL

SUN AND SAND MOTEL
2.0 star property
Spartanburg
7.2 out of 10, Good, (13)
"Wonderful"
United States
Heather
The price is P3,834
P4,256 total
includes taxes & fees
Jan 7 - Jan 8
SUN AND SAND MOTEL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Vacation Rentals in Upstate South Carolina

Cottage
Interior
Clemson Memorabilia House

Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
Clemson
9.8 out of 10, Exceptional, (9)
"We enjoyed our stay, it was the perfect size for our family of four. "
Clemson Memorabilia House
See all vacation rentals
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Southeastern United States attractions

"Clemson University is an American public, coeducational, land-grant and sea-grant research university located in Clemson, South Carolina, United States.More clemson images:"

Clemson University

4.7/5 (738 reviews)
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
See properties
Exploring Falls Park on the Reedy in Downtown Greenville, South Carolina during a peaceful afternoon stroll with scenic views

Falls Park on the Reedy

4.7/5 (1,399 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.
See properties

Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina
The view from Caesars Head after a storm
Photo by Michelle Hendrix
Open Photo by Michelle Hendrix

Top Upstate South Carolina Hotel Reviews

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

10/10 Excellent
"Staff was very nice. Perfect location. Breakfast was good. Room was clean, no carpet, and didn’t smell like mold. "
Krystle 3-night trip
Posted 2 days ago
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

More cheap stays in Upstate South Carolina

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

1007 George Smith Mill Rd Anderson SC
The price is P3,703 per night from Feb 5 to Feb 6
P3,703
P4,110 total
Feb 5 - Feb 6
includes taxes & fees
7.6/10 Good! (1,003 reviews)

Explore a world of travel with Expedia