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Hotels with Air Conditioning in Upstate South Carolina, South Carolina

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Check availability on Upstate South Carolina Hotels with Air Conditioning

Tonight
Dec 25 - Dec 26
Tomorrow
Dec 26 - Dec 27
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Our top choices for Upstate South Carolina hotels with air conditioning

Free daily full breakfast
Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG
2.5 star property
Gaffney
8.6 out of 10, Excellent, (424)
"Great place to stay"
United States
Timothy
The price is P4,581
P4,993 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Holiday Inn Express Gaffney by IHG
Aerial view
Lakeside Lodge Clemson

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1000)
"Great place to stay. "
United States
Gene
The price is P6,402
P7,947 total
includes taxes & fees
Dec 26 - Dec 27
Lakeside Lodge Clemson
Free daily buffet breakfast
Hampton Inn Spartanburg-North I-85

Hampton Inn Spartanburg-North I-85

Hampton Inn Spartanburg-North I-85
2.5 star property
Spartanburg
8.8 out of 10, Excellent, (1000)
"The staff was courteous in the room was spotless!"
United States
Kimberly
The price is P4,575
P5,078 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Hampton Inn Spartanburg-North I-85
Terrace/patio
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center
3.5 star property
Greenville
9.0 out of 10, Wonderful, (1002)
"Great room, staff and location. "
United States
Neil
The price is P5,779
P6,357 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Embassy Suites Greenville Golf Resort & Conference Center
Free daily continental breakfast
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites
2.5 star property
Greenville
9.0 out of 10, Wonderful, (1418)
"Clean room, great selection for breakfast, easy check in and check out"
United States
Angelica
The price is P4,502
P4,953 total
includes taxes & fees
Dec 28 - Dec 29
Best Western Plus Greenville I-385 Inn & Suites
Exterior
DoubleTree by Hilton Greenville Woodruff Road

DoubleTree by Hilton Greenville Woodruff Road

DoubleTree by Hilton Greenville Woodruff Road
3.0 star property
Greenville
9.4 out of 10, Exceptional, (1000)
"Clean modern comfortable convenient location great cookie "
United States
Jimmy
The price is P6,442
P7,087 total
includes taxes & fees
Dec 28 - Dec 29
DoubleTree by Hilton Greenville Woodruff Road
Free daily on-the-go breakfast
Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville
2.5 star property
Greer
8.6 out of 10, Excellent, (730)
"Staff very friendly, clean spacious room"
United States
Arthur
The price is P5,508
P6,004 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Comfort Inn & Suites Greer - Greenville
Reception hall
The Inn at Patrick Square

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (785)
"Everything was clean staff was courteous and accommodating. "
United States
Stewart
The price is P8,751
P9,714 total
includes taxes & fees
Jan 8 - Jan 9, 2026
The Inn at Patrick Square
Fitness facility
Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

Best Western Greenville Airport Inn
2.5 star property
Greenville
7.8 out of 10, Good, (1007)
"Good hotel "
United States
magadan
The price is P4,240
P4,665 total
includes taxes & fees
Dec 26 - Dec 27
Best Western Greenville Airport Inn
Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very Good, (665)
"Friendly check in, clean room."
United States
connie
The price is P4,449
P5,248 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Quality Inn Seneca Clemson Area US-123
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Upstate South Carolina Hotel Reviews

The Westin Poinsett Greenville

The Westin Poinsett Greenville

10/10 Excellent
"Great historic hotel. Great location and awesome staff."
John 2-night trip
Posted 2 days ago
The Westin Poinsett Greenville

Frequently asked questions

How much do hotels with air conditioning in Upstate South Carolina cost?
Prices for hotels with air conditioning in Upstate South Carolina range between P4,665 and P9,714 per night. No matter your budget, you'll be sure to locate the perfect space to enjoy a getaway in air-conditioned comfort. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best hotels with air conditioning in Upstate South Carolina?
Jump straight into vacation mode and unwind in one of Upstate South Carolina's multiple hotels with air conditioning. With a total average guest review rating of 8.7, there's something here for everyone, no matter your style and budget. Many visitors to Greenville recommend staying at Homewood Suites by Hilton Greenville Downtown, a highly rated 3-stars property with designer toiletries, a swimming pool and air conditioning. Another fave in this popular destination is SpringHill Suites by Marriott Greenville Downtown. This 2.5-stars escape features a terrace and a barbecue grill.
How many hotels with air conditioning are there in Upstate South Carolina?
Upstate South Carolina has 181 hotels with air-conditioned rooms to choose from. Enter your destination and dates and book your dream getaway today.
What are the best cheap hotels with air conditioning in Upstate South Carolina?
Save cash on your Upstate South Carolina trip by selecting hotels with air conditioning starting from P4,665 per night. Planning to experience the top attractions of Greenville? Put your bags down at SpringHill Suites by Marriott Greenville Downtown, a money-saving option with AC, a barbecue grill and a terrace. If you're on your way to Spartanburg, Tru by Hilton Spartanburg is an excellent choice. It offers the air-conditioned comfort you need in addition to WiFi and a playground. There are plenty of free and interesting attractions wherever you're headed in Upstate South Carolina. If your journey is taking you to Greenville, swing by Greenville County Museum of Art. You can also tour the sights on a shoestring in Spartanburg. Spartanburg Regional Hospital is one of the most popular free things to do here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top motels with air conditioning in Upstate South Carolina?
Staying in a motel with air conditioning is an excellent way to vacation comfortably at an unbeatable price. If your Upstate South Carolina travels include a spell in Greenville, Urban Boutique Hotel, BW Signature Collection is a recommended choice. It's around 3 kilometers northeast of downtown. With useful amenities like complimentary breakfast and WiFi, it's an economical place to recharge your batteries between sightseeing adventures. Another option with air-conditioned rooms is Days Inn by Wyndham Greenville. It features a swimming pool and front desk services and is situated around 8 kilometers east of central Greenville.There's no shortage of things to keep you entertained in Greenville. The Peace Center and Frankie's Fun Park are great additions to your sightseeing checklist.
Are there any family-friendly hotels with air conditioning in Upstate South Carolina?
You'll find some comfortable family-friendly hotels with air conditioning in Upstate South Carolina. If you're traveling to Greenville, check out SpringHill Suites by Marriott Greenville Downtown. Including air-conditioned rooms and amenities like complimentary breakfast and WiFi, your entire crew will enjoy kicking back at this 2.5-stars property. Hampton Inn & Suites Greenville-Downtown-RiverPlace is another family favorite in Greenville. This 2.5-stars option features complimentary breakfast, housekeeping services and AC. After you've put your bags down and settled in, it's time to explore Greenville. Enjoy memorable moments together at family-friendly attractions like Frankie's Fun Park and Greenville Zoo.
Are there any 5-star hotels with air conditioning in Upstate South Carolina?
While there are no 5-star hotels with air conditioning in Upstate South Carolina, you'll still have a selection of stylish options to choose from. Greenville on your must-see list? The Westin Poinsett Greenville is a 4-star getaway with AC, pillow top mattresses and room service. Greenville Marriott is another recommendation that has the temperature-controlled comfiness you're looking for in Greenville. Also rated 4 stars and offering concierge services and pillow top mattresses, you'll find a lot to love about this hotel.
Why book your hotel with air conditioning in Upstate South Carolina with Expedia?
Expedia has the best prices around for hotels with air conditioning in Upstate South Carolina. If you're on a budget, choose how much you want to spend and your preferred hotel star rating. Then make use of our filters to search for air-conditioned digs with perks like a hot tub or a swimming pool. We'll help you find the perfect place whatever your bank balance or plans.
How can I find cheap hotels with air conditioning in Upstate South Carolina?
Expedia can help you locate cheap hotels with air conditioning in Upstate South Carolina. Simply select the "air conditioned" box under the amenities filter options to view accommodations with this feature. Next, choose your hotel star rating (lower-rated stays are generally cheaper) and your budget per night to find the best places with air conditioning at a competitive price.
What is there to do in Upstate South Carolina near my hotel with air conditioning?
No matter your interests, there are countless things to put on your to-do list in Upstate South Carolina. If you're heading to Greenville, explore The Peace Center, Greenville Zoo and The Children's Museum of the Upstate. Taking off to Spartanburg? Spartanburg Memorial Auditorium, Spartanburg Regional History Museum and Chapman Cultural Center are among the best sights in this city.

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