A coastal fortress with a stone wall and a tiled-roof building.

Luxury Hotels in Syracuse, Sicily

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Check availability on Syracuse Luxury Hotels

Tonight
Sep 10 - Sep 11
Tomorrow
Sep 11 - Sep 12
This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

Our top choices for Syracuse luxury hotels

1. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
  • Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.
P45,032
P50,263 total
includes taxes & fees
Oct 11 - Oct 12
Grand Hotel Des Ètrangers - The Leading Hotels of the World

2. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
Ortigia
  • Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.
P31,777
P35,683 total
includes taxes & fees
Sep 12 - Sep 13
Ortea Palace Hotel, Sicily, Autograph Collection

3. Minareto

Minareto
Syracuse
  • Syracuse seaside splendor offers indulgent relaxation with private beach access, beachfront dining, and Art Deco elegance.
P28,866
P32,480 total
includes taxes & fees
Sep 11 - Sep 12
Minareto

4. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
Syracuse
  • Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness center.
P27,303
P30,762 total
includes taxes & fees
Oct 2 - Oct 3
Wellness & Spa Hotel Principe di Fitalia

5. Charme Hotel Henry's House

Charme Hotel Henry's House
Ortigia
  • Luxurious Mediterranean retreat offers memory foam beds, designer toiletries, and sea-view rooftop terrace in Ortigia.
P24,887
P28,104 total
includes taxes & fees
Oct 9 - Oct 10
Charme Hotel Henry's House

6. Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
Ortigia
  • Relax in a grand Beaux Arts hotel in Ortigia, where upscale comfort meets historic charm steps from Syracuse Cathedral.
P23,214
P26,264 total
includes taxes & fees
Sep 27 - Sep 28
Palazzo Artemide - VRetreats, SLH Collection

7. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
Ortigia
  • Experience luxury at grand hotel with spa services, private beach, and seaside dining in Ortigia.
P22,641
P25,634 total
includes taxes & fees
Oct 7 - Oct 8
Grand Hotel Ortigia Siracusa

8. Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
Ortigia
  • Historic charm meets seaside luxury in Syracuse with private balconies, rainfall showers, and sea-view breakfast.
P17,934
P20,456 total
includes taxes & fees
Sep 26 - Sep 27
Algila' Ortigia Charme Hotel

9. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
Syracuse
  • Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.
P20,973
P23,799 total
includes taxes & fees
Oct 2 - Oct 3
Dimora Caiammari Luxury Hotel & Spa

10. Caportigia Boutique Hotel

Caportigia Boutique Hotel
Santa Lucia
  • Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.
P14,300
P16,458 total
includes taxes & fees
Sep 13 - Sep 14
Caportigia Boutique Hotel
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Top Syracuse Hotel Reviews

 Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

10/10 Excellent
"Clean room , service , staff , shops near , big room"
Louis-Philippe 2-night trip
Posted 14 hours ago
Palazzo Artemide - VRetreats, SLH Collection
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"The hotel was well managed. The restaurant was excellent for both breakfast and dinner. Very well located with a very useful valet service. Highly recommended."
David 4-night trip
Posted 1 day ago
Algila' Ortigia Charme Hotel
Grande Albergo Alfeo

Grande Albergo Alfeo

10/10 Excellent
"Everything was great."
Victoria 4-night trip
Posted 2 days ago
Grande Albergo Alfeo
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"Old world Italian charm and great service. Would have preferred something more centrally located with a pool and better breakfast."
Karen 3-night trip
Posted 11 days ago
Grand Hotel Ortigia Siracusa
Hotel Parco delle Fontane

Hotel Parco delle Fontane

10/10 Excellent
"Please clarify the specific procedures or instructions for gaining access to the facility, particularly regarding the address displayed at the gate."
Salvatore 1-night trip
Posted 2 weeks ago
Hotel Parco delle Fontane

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Syracuse?
Travel to Fontanarossa Airport (CTA) Airport or Vincenzo Magliocco Airport (CIY) Airport, and then treat yourself to a stay at one of 9 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best high-end place to stay in Syracuse?
Ortea Palace Hotel, Sicily, Autograph Collection is a luxury hotel with 2 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Grand Hotel Des Ètrangers - The Leading Hotels of the World and Grand Hotel Ortigia Siracusa are other upscale choices for your vacation.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 9 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 78°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Syracuse is 26 inches.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia, and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Teatro dei Pupi.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To explore the surrounding area, ride one of the trains from Syracuse Station or Targia Station.

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