Syracuse Vacation Rentals

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Check prices for these dates

In two weeks
Jan 9 - Jan 11
In two months
Feb 20 - Feb 22
In three months
Mar 20 - Mar 22
In four months
Apr 17 - Apr 19

Our top choices for Syracuse vacation rentals

Terrace/patio
Thalya Luxury Rooms

Thalya Luxury Rooms

Thalya Luxury Rooms
3.0 star property
Syracuse
9.0 out of 10, Wonderful, (42)
"Wonderful stay!"
United States
Kristie
Thalya Luxury Rooms
Terrace/patio
Alla Giudecca

Alla Giudecca

Alla Giudecca
3.0 star property
Ortigia
8.4 out of 10, Very Good, (273)
"We loved the history of the building, it was beautiful. Spacious rooms with outside sitting area. Walkable to all areas of interest in Ortigia and cafes and restaurants. Staff were helpful. "
United Kingdom
Carol
Alla Giudecca
Front of property
Byssus Suites

Byssus Suites

Byssus Suites
Syracuse
9.8 out of 10, Exceptional, (35)
"Our stay at Byssus Suites was perfect. The location, the spacious and clean suite, and the remarkable staff made for a fantastic stay! Highly recommend. "
United States
Shelli
The price is P13,579
P15,480 total
includes taxes & fees
Dec 29 - Dec 30
Byssus Suites
Memory foam beds, minibar, desk, blackout drapes
Olivia Rooms Teocrito

Olivia Rooms Teocrito

Olivia Rooms Teocrito
3.0 star property
Neapolis
8.0 out of 10, Very Good, (20)
"Easy to walk to main attraction"
United Kingdom
John W
Olivia Rooms Teocrito
Free minibar, desk, soundproofing, free WiFi
Olivia Rooms Eurialo

Olivia Rooms Eurialo

Olivia Rooms Eurialo
3.0 star property
Syracuse
9.2 out of 10, Wonderful, (11)
"Very nice and cosy B&B, the rooms are very freash just like the pics. Good interior and nice bed! Recommend this B&B!"
Sweden
Ka Fai
Olivia Rooms Eurialo
Exterior
Hotel Morfeo Residence

Hotel Morfeo Residence

Hotel Morfeo Residence
3.0 star property
Syracuse
7.4 out of 10, Good, (26)
"The hotel is conveniently located. Everything is walkable. The hotel is quiet. The beds are however awful. Very very hard beds. The kitchen was not well stocked but had basics. "
United States
Gregory Allan
Hotel Morfeo Residence
Reception
Affittacamere Il Terrazzo di Archimede

Affittacamere Il Terrazzo di Archimede

Affittacamere Il Terrazzo di Archimede
Neapolis
8.2 out of 10, Very Good, (27)
"Great value and welcoming host for breakfast. Easily walkable to the sights of Siracusa and ortegia. Clean, comfortable and nice bathroom facilities."
United Kingdom
Stewart
Affittacamere Il Terrazzo di Archimede
Balcony
Nuova Mastrarua Rooms

Nuova Mastrarua Rooms

Nuova Mastrarua Rooms
Ortigia
8.2 out of 10, Very Good, (32)
"This place was an excellent choice - good location to explore Ortiga, the staff was extremely friendly, the hotel is newly renovated, rooms very clean. Definitely recommended. "
Germany
Marvin
The price is P5,658
P6,450 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Nuova Mastrarua Rooms
Reception
Archimede's Rooms

Archimede's Rooms

Archimede's Rooms
Neapolis
9.0 out of 10, Wonderful, (26)
"Everything was excellent! "
United Kingdom
Anonymous traveler
Archimede's Rooms
View from room
1743 Loft Siracusa

1743 Loft Siracusa

1743 Loft Siracusa
1.0 star property
Ortigia
9.0 out of 10, Wonderful, (52)
"We had an amazing time, the owner was so lovely to deal with and the accommodations are so stunning! "
Canada
Laura
The price is P5,658
P8,248 total
includes taxes & fees
Jan 1 - Jan 2, 2026
1743 Loft Siracusa
Balcony
Matteotti Luxury Residence

Matteotti Luxury Residence

Matteotti Luxury Residence
Ortigia
9.8 out of 10, Exceptional, (8)
"Property was clean, safe, and modern. Very efficient check in and out and staff communication was timely and informative. Great place to stay!"
Canada
Andrea
The price is P6,834
P12,465 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Matteotti Luxury Residence
City view from property
Aretusa Vacanze B&B

Aretusa Vacanze B&B

Aretusa Vacanze B&B
1.0 star property
Ortigia
9.6 out of 10, Exceptional, (299)
"Very well run hotel with attentive and attentive staff. "
Canada
Caroline
The price is P5,375
P6,128 total
includes taxes & fees
Jan 24 - Jan 25, 2026
Aretusa Vacanze B&B
Exterior
Le Case Al Quadrato

Le Case Al Quadrato

Le Case Al Quadrato
Syracuse
10.0 out of 10, Exceptional, (1)
"Endroit magnifique, jardin luxuriant et piscine bien entretenue. Cuisine bien équipée, parfait :)"
Canada
Manon
Le Case Al Quadrato
Desk, laptop workspace, free WiFi
Agorà

Agorà

Agorà
Santa Lucia
10.0 out of 10, Exceptional, (2)
"Trevligt, rent, bra service. Hade turen att få balkong. "
Sweden
Olof
The price is P5,407
P6,164 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Agorà
Terrace/patio
Populus

Populus

Populus
1.0 star property
Santa Lucia
7.8 out of 10, Good, (74)
"Just stay somewhere else, plain and simple."
United States
Thomas
The price is P5,092
P5,806 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Populus
View from property
Elsa d'Ortigia - I TRE ARCHI

Elsa d'Ortigia - I TRE ARCHI

Elsa d'Ortigia - I TRE ARCHI
Ortigia
9.4 out of 10, Exceptional, (9)
"Amazing place to stay! Modern, cute, and clean and close to everything! Only thing was water seeping out from the side of the toilet or floor faucet but other than that everything was perfect! "
Canada
Winnie
The price is P5,854
P6,673 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Elsa d'Ortigia - I TRE ARCHI
Water view
Re Dionisio Luxury Suites

Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (57)
"Spacious room, dated but comfortable."
United States
Kenneth
Re Dionisio Luxury Suites
Property entrance
Giuggiulena Villa

Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (126)
"Fantastic stay. Made to feel very welcome and what a lovely relaxing place to stay. Evening meal was exceptional. "
United States
Paul
The price is P13,737
P15,660 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Giuggiulena Villa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Syracuse Hotel Reviews

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"Every aspect of our stay was superb. The staff were friendly and helpfull. Our room was spotless, and the decor of the entire hotel was harmonious. "
Thomas 2-night trip
Posted 4 days ago
Grand Hotel Ortigia Siracusa

Find out more about Syracuse

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Frequently asked questions

Can I find vacation rentals in Syracuse?

Yes, we offer vacation rentals in Syracuse close to Arkimedeion Museum, or you can choose a more secluded option if you want a relaxing stay. Visitors like the scenic seaside and cathedral in Syracuse. While you're here, grab a bite or have a drink at the cafes.

How many vacation rentals are there in Syracuse?

Choose from 312 Expedia vacation rentals in Syracuse for a memorable vacation.

What’s there to see and do in Syracuse?

Enjoy the outdoors at Fanusa Beach and Arenella Beach, or simply take in cultural attractions like Teatro dei Pupi and Syracuse Municipal Theater. Other places in town to visit include Temple of Apollo and Lungomare di Ortigia.

What’s a vacation rental in Syracuse like?

A vacation rental is a private property where you can stay for a couple of days or more in Syracuse. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, a vacation rental can provide a sense of security away from shared hotel elevators and busy lobbies while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a hotel, which makes a vacation rental an attractive choice for small groups.