Photo by throwingsofas

Southwest Illinois Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Go beyond your typical stay in Southwest Illinois

Check prices for these dates

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Southwest Illinois hotels

1. Best Western U. S. Inn

Best Western U. S. Inn
2.5 star property
Nashville
8.6 out of 10, Excellent, (460 reviews)
"Worked well for our short stay."
United States
Steven
The price is P7,597
P8,279 total
includes taxes & fees
Nov 11 - Nov 12
Best Western U. S. Inn

2. Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (689 reviews)
"We stayed here with 2 adults and 3 kids and it was perfect. We highly recommend staying here"
United States
Jeremy
The price is P8,801
P9,855 total
includes taxes & fees
Nov 11 - Nov 12
Best Western Plus Centralia Hotel & Suites

3. Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
2.5 star property
Mount Vernon
8.8 out of 10, Excellent, (1,005 reviews)
"Great spacious room. Breakfast was awesome and the helper was outstanding! Great food and coffee."
United States
Doug
The price is P6,775
P7,645 total
includes taxes & fees
Dec 11 - Dec 12
Holiday Inn Express & Suites Mount Vernon by IHG

4. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.5 star property
Mount Vernon
9.8 out of 10, Exceptional, (1,869 reviews)
"Nice comfortable stay"
United States
Mei
The price is P7,027
P7,926 total
includes taxes & fees
Nov 15 - Nov 16
Drury Plaza Hotel Mt. Vernon

5. Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,093 reviews)
"Great bathroom"
United States
Bruce and Robin
The price is P7,519
P8,471 total
includes taxes & fees
Nov 15 - Nov 16
Comfort Suites Mount Vernon

6. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
3.0 star property
Mount Vernon
8.8 out of 10, Excellent, (734 reviews)
"Beautiful property very clean when you enter the lobby is very impressive in the staff was very helpful. Our room was clean in the morning. Breakfast was great."
United States
Susan
The price is P6,901
P7,786 total
includes taxes & fees
Nov 12 - Nov 13
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

7. Hampton Inn O'Fallon

Hampton Inn O'Fallon
2.5 star property
O'Fallon
9.2 out of 10, Wonderful, (895 reviews)
"The gentleman checking us in and the one checking us out were both very friendly and welcoming, plus the one checking us in was very helpful telling us about the facility we didn’t need to ask any questions… property was very bright and clean and safe. Also appeared to have been updated in the last few years, no dingy poorly lit hallways, everything well maintained, room was very spacious and clean"
United States
Beverly
The price is P7,212
P8,364 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn O'Fallon

8. Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (725 reviews)
"Clean rooms, complimentary breakfast, great value."
United States
Ryan
The price is P4,559
P5,186 total
includes taxes & fees
Nov 22 - Nov 23
Quality Inn Mount Vernon, IL

9. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
4.0 star property
Mount Vernon
8.4 out of 10, Very good, (910 reviews)
"Loved the onsite bar and the location of the hotel"
United States
Tammi
The price is P8,097
P9,112 total
includes taxes & fees
Nov 13 - Nov 14
DoubleTree by Hilton Mt. Vernon

10. Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
2.5 star property
Mount Vernon
8.0 out of 10, Very good, (1,011 reviews)
"Everything was clean, nice hotel"
United States
Leslie
The price is P4,622
P5,256 total
includes taxes & fees
Nov 15 - Nov 16
Super 8 by Wyndham Mt. Vernon IL

11. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (1,003 reviews)
"Very clean and everything was perfect!"
United States
Tad
The price is P4,843
P5,375 total
includes taxes & fees
Dec 1 - Dec 2
SureStay Hotel by Best Western Whittington Rend Lake

12. Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
2.5 star property
Mascoutah
9.0 out of 10, Wonderful, (1,008 reviews)
"Everything exceeded my expectations! Great stay!"
United States
Charles
The price is P6,379
P7,271 total
includes taxes & fees
Nov 15 - Nov 16
Best Western Plus MidAmerica Hotel

13. Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG
2.5 star property
Sparta
9.2 out of 10, Wonderful, (435 reviews)
"Clean property and friendly staff"
United States
Jo Ann
The price is P5,572
P6,183 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Express Hotel & Suites Sparta by IHG

14. Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL
3.0 star property
O'Fallon
9.4 out of 10, Exceptional, (1,008 reviews)
"Staff was very friendly"
United States
Karissa
The price is P6,458
P7,489 total
includes taxes & fees
Nov 15 - Nov 16
Drury Inn & Suites St. Louis O'Fallon, IL

15. Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57
2.5 star property
Marion
9.4 out of 10, Exceptional, (1,001 reviews)
"Clean and comfortable room. Breakfast options were very good!"
United States
Suzan
The price is P7,373
P8,846 total
includes taxes & fees
Nov 22 - Nov 23
Comfort Inn & Suites Marion I-57

16. Fairfield Inn & Suites by Marriott O'Fallon, IL

Fairfield Inn & Suites by Marriott O'Fallon, IL
3.0 star property
O'Fallon
9.2 out of 10, Wonderful, (372 reviews)
"Great hotel"
United States
Mohamad
The price is P8,774
P10,088 total
includes taxes & fees
Nov 25 - Nov 26
Fairfield Inn & Suites by Marriott O'Fallon, IL

17. Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL
2.5 star property
Marion
8.6 out of 10, Excellent, (1,009 reviews)
"friendly staff, comfortable rooms, breakfast a plus."
United States
Rhonda
The price is P7,174
P8,608 total
includes taxes & fees
Nov 22 - Nov 23
Country Inn & Suites by Radisson, Marion, IL

18. TownePlace Suites by Marriott St. Louis O'Fallon

TownePlace Suites by Marriott St. Louis O'Fallon
3.0 star property
O'Fallon
9.0 out of 10, Wonderful, (159 reviews)
"Conditioner would not pump anything out and even trying to take it out of the holster was impossible. And the pool was freezing cold. I thought it was a heated pool. Other than that, everything else was excellent."
United States
Bethany
The price is P8,294
P9,620 total
includes taxes & fees
Nov 29 - Nov 30
TownePlace Suites by Marriott St. Louis O'Fallon

19. Red Bud Country Inn

Red Bud Country Inn
2.5 star property
Red Bud
8.8 out of 10, Excellent, (81 reviews)
"It was nice and clean, the staffs were accommodating."
United States
Camille
The price is P5,566
P6,177 total
includes taxes & fees
Nov 11 - Nov 12
Red Bud Country Inn

20. Super 8 by Wyndham Du Quoin

Super 8 by Wyndham Du Quoin
2.0 star property
Du Quoin
7.0 out of 10, Good, (403 reviews)
"When first walking into the room the air was stale as the air unit had been kept completely off, but once turned on it wasn’t noticeable anymore. The room was very dated and definitely needed a facelift. However it was kept very clean with comfortable bedding. If I needed to stay overnight in this town again I would choose here."
United States
Nathanael
The price is P5,382
P5,973 total
includes taxes & fees
Nov 11 - Nov 12
Super 8 by Wyndham Du Quoin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southwest Illinois attractions

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

A tall, cylindrical structure with a red and white striped pattern and a label reading "Brock's Old Original Catsup."
Photo by throwingsofas
Open Photo by throwingsofas