Hotels in Southwest Illinois from P3,781 for 2026 - Fully Refundable Options

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Our top choices for Southwest Illinois hotels

A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.

A reception area with a stone wall, a round mirror, a reception desk, and a computer setup.

A Best Western U.S. Inn with a modern design, featuring a covered entrance and a parking lot.

A hotel room with two beds, a desk, and a window with a view.

1. Best Western U. S. Inn

Nashville

Arilla

P6,872

P7,489 total

includes taxes & fees

Oct 1 - Oct 2

A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

A spacious lobby with a large seating area, a reception desk, and a television.

An indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls. There are lounge chairs and a small seating area with tables.

A hotel room with two beds, a large window with curtains, a wall-mounted lamp, and a patterned carpet.

2. Best Western Plus Centralia Hotel & Suites

Centralia

Corey

P8,684

P9,724 total

includes taxes & fees

Oct 4 - Oct 5

A bar area with a long counter, multiple chairs, and hanging light fixtures.

A spacious lobby with a reception desk, seating area, and glass doors leading outside.

A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.

A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.

3. Drury Plaza Hotel Mt. Vernon

Mount Vernon

Kirstyn

P6,934

P7,820 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A parking lot with a Super 8 sign, a white car, and a truck.

A hotel room with a desk, a lamp, a flat-screen TV, a telephone, a microwave, and a trash bin.

A hotel with a brick facade, a flagpole with an American flag, and a parking lot with several cars.

4. Super 8 by Wyndham Mt. Vernon IL

Mount Vernon

Devin

P4,580

P5,209 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with a large bed, a red bedspread, a bathtub, a nightstand with a lamp, and two framed pictures on the wall.

A hotel room with a sofa, two lamps, a television, and a desk.

A kitchen with a dishwasher, coffee makers, a water dispenser, and various kitchen utensils.

A hotel room with a bed, a desk with a TV, a chair, a small table, and a couch.

5. Seasons Inn & Suites Highland

Highland

Jeffrey

P5,609

P6,225 total

includes taxes & fees

Oct 4 - Oct 5

A small, clean room with a microwave, a vending machine, and a table with chairs.

A bathroom with a shower, a bathtub, and a toilet.

A hotel room with two beds, a small kitchenette, and a dining area.

A reception area with a wooden counter, a tiled floor, and a wall with framed pictures.

6. Rodeway Inn Mount Vernon, IL

Mount Vernon

Emil

P4,248

P4,840 total

includes taxes & fees

Oct 25 - Oct 26

A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and illuminated pillars.

An indoor swimming pool with clear lane markings, a lifeguard chair, and a window providing natural light.

A hotel room with two beds, a large window, and a wall-mounted lamp.

A buffet with labeled food options including turkey sausage and bacon.

7. Holiday Inn Express & Suites Mount Vernon by IHG

Mount Vernon

John

P6,935

P7,821 total

includes taxes & fees

Oct 24 - Oct 25

A hotel lobby with a reception desk, seating area, and a large screen TV.

A hotel room with a marble bathtub, a wooden dining table with chairs, a bed with a headboard, and a nightstand with lamps.

A hotel dining area with a large wooden table, red upholstered chairs, a flat-screen TV mounted above the fireplace, and a kitchen area in the background.

A brick building with a patio area featuring wicker furniture and a table.

8. Comfort Suites Mount Vernon

Mount Vernon

Lori

P7,347

P8,279 total

includes taxes & fees

Oct 18 - Oct 19

A brick building with a wooden gazebo in front.

A hotel room with two beds, a dresser, a television, and a bathroom visible through an open door.

A statue of a Native American figure with a horse, a Route 66 sign, a map, and a clock on the wall.

A compact kitchen with a sink, microwave, and stove, a wooden cabinet, and a television mounted on the wall.

9. Country Hearth Inn & Suites Edwardsville St. Louis

Edwardsville

Sarah

P8,059

P9,266 total

includes taxes & fees

Sep 27 - Sep 28

A neatly made bed with a patterned bedspread, a framed picture above it, a chair, a lamp, and a checkered floor.

A room with teal walls, a wooden desk, a chair, a television, a lamp, a microwave, and a coat rack.

Two double beds with patterned headboards, a bedside table with a lamp, and framed pictures on the wall.

10. Powhatan Motel

Pocahontas

Chris

P6,044

P6,406 total

includes taxes & fees

Oct 23 - Oct 24

A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.

A dining area with round tables and chairs, a kitchen with a countertop and appliances, and a hallway leading to another room.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A hotel with a flat facade, multiple windows, and a sign indicating it is a 'SureStay Hotel by Best Western'.

11. SureStay Hotel by Best Western Whittington Rend Lake

Whittington

MARK

P5,082

P5,640 total

includes taxes & fees

Oct 4 - Oct 5

A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.

A modern hotel room with a living area, a kitchenette, and a door leading to another room.

A spacious lobby with a stone reception desk, leather seating, and a large window offering a view of the outdoors.

A hotel room with a large bed, a desk with a chair, a sofa, and a TV.

12. Best Western Plus MidAmerica Hotel

Mascoutah

Danny

P6,844

P7,801 total

includes taxes & fees

Sep 29 - Sep 30

An indoor swimming pool area with multiple lanes, lounge chairs, and a small seating area.

A lobby with two armchairs, a lamp, a framed artwork, and a sign indicating a fitness center.

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

A lobby with patterned sofas, a fireplace, and framed pictures on the wall.

13. Drury Inn & Suites St. Louis O'Fallon, IL

O'Fallon

KEVIN

P6,372

P7,390 total

includes taxes & fees

Oct 19 - Oct 20

A kitchen with granite countertops, wooden cabinets, a coffee maker, a microwave, and a potted plant.

A Super 8 motel with a two-story structure, a covered entrance, and a parking lot.

A hotel room with a bed, two bedside lamps, a chair, a desk, and a large window with curtains.

A furnished living room with a sofa, a coffee table, a television, and a small table with a plant.

14. Super 8 by Wyndham Du Quoin

Du Quoin

Wendy

P5,310

P5,893 total

includes taxes & fees

Oct 3 - Oct 4

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows offering views of the outside.

A lobby with a fireplace, blue armchairs, a brown sofa, and a patterned carpet.

A hotel room with a bed, a desk, a chair, and a small table.

A Best Western hotel with a large sign, multiple parking spaces, and a well-lit entrance.

15. Best Western Troy Hotel

Troy

joshua

P5,567

P6,178 total

includes taxes & fees

Sep 29 - Sep 30

A hotel room with a large flat-screen TV, a desk with drawers, a bench, and a wardrobe.

A compact hotel room with a kitchenette, a blue sofa, a small wooden table, and a wooden floor.

A patio area with outdoor seating, including chairs and tables, and a covered area with umbrellas.

A hot tub area with a view of the parking lot through a glass door.

16. Holiday Inn Express Hotel & Suites Sparta by IHG

Sparta

Jeremy

P6,622

P7,349 total

includes taxes & fees

Oct 25 - Oct 26

A restaurant with multiple tables and booths, large windows, and a modern interior design.

A hotel named "The Principal Hotel" with a brick facade, multiple windows, and a parking lot in front.

A neatly made bed with white linens and a dark headboard, flanked by two bedside tables with lamps.

A modern kitchen with a central island, bar stools, and a dining area.

17. The Principal Hotel

Columbia

Kenny

P6,129

P6,802 total

includes taxes & fees

Sep 27 - Sep 28

A modern living room with a fireplace, blue sofa, red chairs, and a flat-screen TV mounted on a textured wall.

A hotel reception area with a computer desk, a printer, a coffee machine, and a framed cityscape picture on the wall.

A hotel room with a blue armchair, a sofa, a bed, a desk, a television, and a window.

18. Comfort Inn & Suites Greenville I-70

Greenville

Debbie

P6,337

P7,033 total

includes taxes & fees

Oct 25 - Oct 26

A bathroom with a bathtub, a sink, and a mirror.

A room with a bed, a bench, a sink, a door, and a bathtub.

A living room with a sofa, a wooden table, a television, a microwave, and a window with curtains.

A two-story motel with a covered entrance and a parking lot.

19. Americas Best Value Inn West Frankfort

West Frankfort

Christopher

P4,248

P4,715 total

includes taxes & fees

Oct 19 - Oct 20

A row of motel-style buildings with individual rooms, each with a separate entrance.

A kitchen with wooden cabinets, a coffee maker, and a countertop with various items.

20. Gray Plaza Motel Benton Rend Lake I-57

Benton

William

P3,998

P4,837 total

includes taxes & fees

Oct 23 - Oct 24

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Stay near popular Southwest Illinois attractions

World Wide Technology Raceway

9.0/10 (2 reviews)

Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

See properties

O'Fallon Family Sports Park

8.6/10 (137 reviews)

Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Check out the shops and top-notch restaurants in this family-friendly area.

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DuQuoin State Fairgrounds

8.2/10 (95 reviews)

Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.

See properties

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

See all hotels in Southwest Illinois

A tall, modern tower with balconies, set against a clear blue sky.

Top Southwest Illinois Hotel Reviews

The Principal Hotel

10/10 Excellent

"Good"

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

10/10 Excellent

"Clean room. Great breakfast. Convenient parking."

Drury Inn & Suites St. Louis Collinsville

10/10 Excellent

"Best bacon .."

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent

"Staff very professional and friendly. Food delicious."

Super 8 by Wyndham O'Fallon

10/10 Excellent

"Clean"

Radisson Hotel Fairview Heights - St. Louis

8/10 Good

"clean pretty quiet and close to i64"

Comfort Suites Fairview Heights - St. Louis

10/10 Excellent

"Enjoyed our stay for the most part. Breakfast wasnt kept up with and stayed empty both days we stayer."

More cheap stays in Southwest Illinois

Americas Best Value Inn Collinsville St. Louis

552 Ramada Blvd Collinsville IL

P3,288

P3,781 total

Oct 18 - Oct 19

includes taxes & fees

6.4/10 (976 reviews)

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL

P3,346

P3,847 total

Oct 20 - Oct 21

includes taxes & fees

6.6/10 (1,108 reviews)

Super 8 by Wyndham Collinsville St. Louis

2 Gateway Dr Collinsville IL

P4,620

P5,312 total

Oct 18 - Oct 19

includes taxes & fees

7/10 Good! (1,003 reviews)

Best Western St. Louis Fairview Heights

150 Ludwig Dr Fairview Heights IL

P5,257

P5,940 total

Sep 29 - Sep 30

includes taxes & fees

Comfort Inn Edwardsville - St. Louis

3080 S State Route 157 Edwardsville IL

P5,948

P6,839 total

Oct 18 - Oct 19

includes taxes & fees

8.4/10 Very Good! (950 reviews)

Baymont by Wyndham Marion

2608 W Main St Marion IL

P5,994

P7,192 total

Oct 25 - Oct 26

includes taxes & fees

8.4/10 Very Good! (1,091 reviews)

Southwest Illinois Hotels

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Southwest Illinois

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Southwest Illinois hotels

1. Best Western U. S. Inn

2. Best Western Plus Centralia Hotel & Suites

3. Drury Plaza Hotel Mt. Vernon

4. Super 8 by Wyndham Mt. Vernon IL

5. Seasons Inn & Suites Highland

6. Rodeway Inn Mount Vernon, IL

7. Holiday Inn Express & Suites Mount Vernon by IHG

8. Comfort Suites Mount Vernon

9. Country Hearth Inn & Suites Edwardsville St. Louis

10. Powhatan Motel

11. SureStay Hotel by Best Western Whittington Rend Lake

12. Best Western Plus MidAmerica Hotel

13. Drury Inn & Suites St. Louis O'Fallon, IL

14. Super 8 by Wyndham Du Quoin

15. Best Western Troy Hotel

16. Holiday Inn Express Hotel & Suites Sparta by IHG

17. The Principal Hotel

18. Comfort Inn & Suites Greenville I-70

19. Americas Best Value Inn West Frankfort

20. Gray Plaza Motel Benton Rend Lake I-57

Stay near popular Southwest Illinois attractions

World Wide Technology Raceway

O'Fallon Family Sports Park

DuQuoin State Fairgrounds

Learn more about Southwest Illinois

Top Southwest Illinois Hotel Reviews

The Principal Hotel

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis O'Fallon, IL

Super 8 by Wyndham O'Fallon

Radisson Hotel Fairview Heights - St. Louis

Comfort Suites Fairview Heights - St. Louis

More cheap stays in Southwest Illinois

Americas Best Value Inn Collinsville St. Louis

Super 8 by Wyndham O'Fallon

Super 8 by Wyndham Collinsville St. Louis

Best Western St. Louis Fairview Heights

Comfort Inn Edwardsville - St. Louis

Baymont by Wyndham Marion

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