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Southwest Illinois Hotels

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Our top choices for Southwest Illinois hotels

Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
2.5 star property
Mascoutah
9.0 out of 10, Wonderful, (1004)
"Very clean room, friendly staff and wonderful hot breakfast! This was our third stay, Highly recommend!!!!"
United States
Amber
The price is P6,436
P7,335 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Best Western Plus MidAmerica Hotel

Fairgrounds Inn

Fairgrounds Inn
2.0 star property
Du Quoin
7.6 out of 10, Good, (380)
" Stayed with the family and they made sure that we had rooms next to each other. Very friendly staff."
United States
Julie
Fairgrounds Inn

Days Inn by Wyndham Mount Vernon

Days Inn by Wyndham Mount Vernon
2.0 star property
Mount Vernon
6.8 out of 10, (1000)
"Clean room. Heater worked great!! Staff is very friendly. "
United States
Michele
The price is P3,446
P3,941 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Days Inn by Wyndham Mount Vernon

Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (543)
"Clean quiet"
United States
Gina
The price is P4,230
P4,812 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Quality Inn Mount Vernon, IL

Super 8 by Wyndham Salem

Super 8 by Wyndham Salem
2.0 star property
Salem
7.2 out of 10, Good, (710)
"Room, office okay. Next Super 8 in Bryant AR was even nicer, well kept room, maybe renovated "
Canada
Dianne
The price is P3,293
P3,621 total
includes taxes & fees
Dec 29 - Dec 30
Super 8 by Wyndham Salem

Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
4.5 star property
Carterville
9.4 out of 10, Exceptional, (392)
"Finally a decent place to stay while visiting Carbondale. Great taste place. Clean. Super friendly. The best in town. "
United States
David
The price is P7,340
P8,146 total
includes taxes & fees
Dec 29 - Dec 30
Walker's Bluff Casino Resort

Quality Inn & Suites Salem near I-57

Quality Inn & Suites Salem near I-57
2.5 star property
Salem
7.2 out of 10, Good, (496)
"Everything was smooth and efficient "
United States
Tashawna
The price is P4,195
P4,613 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Quality Inn & Suites Salem near I-57

Econo Lodge Inn & Suites Fairview Heights - St. Louis

Econo Lodge Inn & Suites Fairview Heights - St. Louis
2.0 star property
Fairview Heights
7.4 out of 10, Good, (594)
"Na"
United States
Bridget
The price is P3,756
P4,244 total
includes taxes & fees
Jan 27 - Jan 28, 2026
Econo Lodge Inn & Suites Fairview Heights - St. Louis

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
2.5 star property
Mount Vernon
8.8 out of 10, Excellent, (685)
"Good place to stay."
United States
Timothy
The price is P5,891
P6,655 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

DoubleTree by Hilton Collinsville - St. Louis

DoubleTree by Hilton Collinsville - St. Louis
4.0 star property
Eastport
8.2 out of 10, Very Good, (1001)
"Nice restaurant "
United States
Shelly
The price is P7,178
P8,253 total
includes taxes & fees
Jan 26 - Jan 27, 2026
DoubleTree by Hilton Collinsville - St. Louis

Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1006)
"Check in was quick, staff was friendly and helpful, room was very nice and clean."
United States
Don
The price is P6,384
P7,202 total
includes taxes & fees
Dec 30 - Dec 31
Comfort Suites Mount Vernon

Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1003)
"Clean and staff friendly "
United States
Tim
The price is P5,816
P6,572 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express & Suites Mount Vernon by IHG

Motel 6 Mount Vernon, IL

Motel 6 Mount Vernon, IL
2.0 star property
Mount Vernon
7.2 out of 10, Good, (940)
"Nice staff, beds need updated. No housekeeping in four days."
United States
kai
The price is P3,583
P4,094 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Motel 6 Mount Vernon, IL

Quality Inn & Suites near St. Louis and I-255

Quality Inn & Suites near St. Louis and I-255
2.5 star property
Cahokia
7.4 out of 10, Good, (1001)
"Great value."
United States
Todd
The price is P4,147
P4,686 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Quality Inn & Suites near St. Louis and I-255

Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (1003)
"reception was great, room clean, and the price was right."
United States
tom
The price is P3,701
P4,225 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Super 8 by Wyndham Mt. Vernon IL

DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
4.0 star property
Mount Vernon
8.4 out of 10, Very Good, (769)
"What stood out for us were the amenities. This hotel has amazing spaces for meetings or conversation groups. The breakfast buffet was amazing. And there were the cookies!"
United States
Glenn
The price is P7,513
P8,455 total
includes taxes & fees
Jan 1 - Jan 2, 2026
DoubleTree by Hilton Mt. Vernon

Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville
3.0 star property
Eastport
9.6 out of 10, Exceptional, (1003)
"Nice to have food and drinks provided "
United States
MICHAEL
The price is P5,757
P6,619 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Drury Inn & Suites St. Louis Collinsville

Candlewood Suites O Fallon by IHG

Candlewood Suites O Fallon by IHG
2.5 star property
O'Fallon
7.8 out of 10, Good, (399)
"The room was better than what i expected with it being a studio. Bed comfy and the kitchen stocked with dishware. Very pleased."
United States
Genevive
The price is P5,522
P6,349 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Candlewood Suites O Fallon by IHG

Fairfield Inn by Marriott St. Louis Collinsville, IL

Fairfield Inn by Marriott St. Louis Collinsville, IL
2.5 star property
Eastport
8.2 out of 10, Very Good, (402)
"Clean rook hot ahower front ladt was nothing short of awesome"
United States
Mike
The price is P5,763
P6,626 total
includes taxes & fees
Jan 24 - Jan 25, 2026
Fairfield Inn by Marriott St. Louis Collinsville, IL

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights
3.0 star property
Fairview Heights
9.2 out of 10, Wonderful, (1004)
"Great stay"
United States
Marlin
The price is P5,522
P6,238 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Drury Inn & Suites St. Louis Fairview Heights
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Central United States attractions

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

One of the northermost cypress swamps in the States, the Cache River State Natural area is home to Cypress trees that are over 1000 years old. This is shot from the hiking trail (no boat), and was just a sampling of the scores of cypress trees all around. #treetrove
Photo by Carl Anderson
Open Photo by Carl Anderson

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