A calm lake surrounded by trees and vegetation.

Southwest Illinois Hotels

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Our top choices for Southwest Illinois hotels

Holiday Inn Express & Suites Vandalia by IHG

Holiday Inn Express & Suites Vandalia by IHG
2.5 star property
Vandalia
8.8 out of 10, Excellent, (837 reviews)
"Easy access fro I70.. Hotel very full but breakfast dining was clean & stocked."
United States
Joyce
The price is P6,621
P7,216 total
includes taxes & fees
Jul 5 - Jul 6
Holiday Inn Express & Suites Vandalia by IHG

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.5 star property
Mount Vernon
9.6 out of 10, Exceptional, (1,709 reviews)
"A nice stay"
United States
DAVID
The price is P6,866
P7,743 total
includes taxes & fees
Jul 12 - Jul 13
Drury Plaza Hotel Mt. Vernon

Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,053 reviews)
"Quick and easy check in, fruendly staff, bed and pillows were super comfy and the breakfast was great. "
United States
Todd
The price is P7,513
P8,461 total
includes taxes & fees
Jul 5 - Jul 6
Comfort Suites Mount Vernon

Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 star property
Vandalia
8.4 out of 10, Very Good, (1,001 reviews)
"Place was great. Not to bad for a great place to crash after a day of fishing."
United States
Dawn
The price is P4,144
P4,516 total
includes taxes & fees
Jul 5 - Jul 6
Quality Inn & Suites Vandalia near I-70 and Hwy 51

Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (845 reviews)
"The room was nice and the staff was very helpful"
United States
Tammy
The price is P5,027
P5,479 total
includes taxes & fees
Jul 5 - Jul 6
Ramada by Wyndham Vandalia

Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (1,002 reviews)
"Nice staff, clean rooms"
United States
Theresa
The price is P4,304
P4,899 total
includes taxes & fees
Jun 29 - Jun 30
Super 8 by Wyndham Mt. Vernon IL

SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (987 reviews)
"Staff was friendly room was clean"
United States
Brandon
The price is P5,241
P5,817 total
includes taxes & fees
Jul 5 - Jul 6
SureStay Hotel by Best Western Whittington Rend Lake

Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
2.5 star property
Mascoutah
9.0 out of 10, Wonderful, (1,001 reviews)
"Super close to mid America airport. Great breakfast and they had complimentary chili in the evening."
United States
Scot
The price is P6,986
P7,963 total
includes taxes & fees
Jun 30 - Jul 1
Best Western Plus MidAmerica Hotel

Americas Best Value Inn West Frankfort

Americas Best Value Inn West Frankfort
2.5 star property
West Frankfort
7.6 out of 10, Good, (519 reviews)
"Room was clean and very comfortable! Staff was great!"
United States
Byron
The price is P4,721
P5,239 total
includes taxes & fees
Jul 3 - Jul 4
Americas Best Value Inn West Frankfort

Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,000 reviews)
"Clean room, friendly staff, ver attentive and thoughtful at breakfast."
United States
Melissa
The price is P7,480
P8,424 total
includes taxes & fees
Jul 1 - Jul 2
Holiday Inn Express & Suites Mount Vernon by IHG

Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1,006 reviews)
"Clean room, great breakfast and evening drinks & food. Friendly staff."
United States
Brandy
The price is P6,805
P8,164 total
includes taxes & fees
Jul 20 - Jul 21
Drury Inn & Suites Marion

Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL
2.5 star property
Chester
8.6 out of 10, Excellent, (399 reviews)
"Nice place"
United States
Doug
The price is P4,966
P5,511 total
includes taxes & fees
Jul 4 - Jul 5
Baymont by Wyndham Chester IL

Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70
2.5 star property
Greenville
8.4 out of 10, Very Good, (449 reviews)
"Property was ok Breakfast was good "
United States
Alan
The price is P6,683
P7,417 total
includes taxes & fees
Jul 5 - Jul 6
Comfort Inn & Suites Greenville I-70

The Principal Hotel

The Principal Hotel
3.5 star property
Columbia
9.6 out of 10, Exceptional, (320 reviews)
"Great hotel and nice staff!"
United States
Michelle
The price is P6,916
P7,676 total
includes taxes & fees
Jun 29 - Jun 30
The Principal Hotel

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
Troy
8.0 out of 10, Very Good, (1,003 reviews)
"Good customer service well put together hotel"
United States
Donta
The price is P4,414
P4,899 total
includes taxes & fees
Jun 29 - Jun 30
Super 8 by Wyndham Troy IL/St. Louis Area

Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia
2.5 star property
Columbia
8.6 out of 10, Excellent, (514 reviews)
"The staff was all friendly & very helpful. The room was very comfortable & clean. Breakfast had many choices & was delicious!!! Definitely staying here on all our trips in this area."
United States
Angie
The price is P5,983
P6,639 total
includes taxes & fees
Jul 5 - Jul 6
Hampton Inn St. Louis - Columbia

Best Western Saluki Inn

Best Western Saluki Inn
2.5 star property
Carbondale
8.0 out of 10, Very Good, (1,003 reviews)
"The place was nice, clean, and staff was very friendly. We will stay here agin next year."
United States
Jarrod
The price is P5,640
P6,607 total
includes taxes & fees
Jul 1 - Jul 2
Best Western Saluki Inn

Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (644 reviews)
"The staff were friendly and helpful"
United States
Lisa
The price is P9,135
P10,229 total
includes taxes & fees
Jun 29 - Jun 30
Best Western Plus Centralia Hotel & Suites

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
Edwardsville
8.6 out of 10, Excellent, (718 reviews)
"We had a great stay and the breakfast was really good."
United States
Tonya
The price is P7,909
P9,093 total
includes taxes & fees
Jul 1 - Jul 2
Country Hearth Inn & Suites Edwardsville St. Louis

Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (645 reviews)
"This was a good hotel for a stop over on a 3 day trip across country."
United States
Cinda
The price is P4,635
P5,267 total
includes taxes & fees
Jul 12 - Jul 13
Quality Inn Mount Vernon, IL
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Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

A swampy area with tall, thin trees and water reflecting the sky.
Photo by Carl Anderson
Open Photo by Carl Anderson

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