A calm lake surrounded by trees and vegetation.

Hotels with Spa in Southwest Illinois, Illinois

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Check availability on Southwest Illinois Hotels with Spa

Tonight
Sep 29 - Sep 30
Tomorrow
Sep 30 - Oct 1
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Our top choices for Southwest Illinois hotels with a spa

A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.
A hotel lobby with a marble floor, a reception area with a '12 & VINE' sign, and a dining area with orange chairs and chandeliers.
A casino interior with slot machines, a large chandelier, and a carpeted floor.

1. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
  • Luxurious spa retreat with hot stone massages, sauna, and seasonal pools awaits at this casino resort with attentive staff and fine dining.
P10,692
P11,866 total
includes taxes & fees
Oct 14 - Oct 15
Walker's Bluff Casino Resort
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A two-story building with a dark entrance, large windows, and a brick facade.
A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.
A room with a green armchair, a round table, a lamp, and a mirror on the wall.

2. Truitt Hotel

Truitt Hotel
Lafayette Square
P11,758
P14,218 total
includes taxes & fees
Oct 6 - Oct 7
Truitt Hotel
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

3. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
  • Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
P6,192
P7,047 total
includes taxes & fees
Oct 29 - Oct 30
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A modern bathroom with a bathtub, a vanity with a mirror, and a shower area.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.

4. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
P8,990
P10,825 total
includes taxes & fees
Oct 25 - Oct 26
21C Museum Hotel St Louis
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A bakery display case with various pastries and cakes.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

5. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
P9,340
P11,954 total
includes taxes & fees
Oct 14 - Oct 15
Ameristar Casino Resort and Spa
A couple relaxing by a window overlooking a bridge and water.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.
A modern hotel lobby with a glass facade, seating area, and a staircase.

6. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
P23,454
P27,424 total
includes taxes & fees
Oct 4 - Oct 5
Four Seasons Hotel St Louis
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
A couple standing on a balcony with a cityscape view.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.

7. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
P38,715
P45,195 total
includes taxes & fees
Oct 18 - Oct 19
The Ritz-Carlton, St. Louis
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Choose what matters most at spa hotels in Southwest Illinois

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Southwest Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Everything was great clean staff was great food was great can’t wait to go back"
Barbara 1-night trip
Posted 5 hours ago
Drury Plaza Hotel Mt. Vernon
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

8/10 Good
"Finally a room with a walk in shower and grab bars by toilet"
Anjanette 1-night trip
Posted 11 hours ago
Comfort Suites Mount Vernon
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent
"Fabulous that I arrived & had Happy Hour Meal with Drinks & a great breakfast! Thx! Dennis D."
Dennis 1-night trip
Posted 1 day ago
Drury Inn & Suites St. Louis O'Fallon, IL

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