A modern glass building with a curved facade and a sign reading "The Kentucky Center".

Hotels with Spa in Southern Indiana, United States of America

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Check availability on Southern Indiana Hotels with Spa

Tonight
Oct 26 - Oct 27
Tomorrow
Oct 27 - Oct 28
This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Southern Indiana hotels with a spa

A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.
A modern interior with a fireplace, bookshelves, and seating areas.
A lobby with a marble floor, a reception desk, and a large chandelier.

1. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
  • Immerse in spa bliss at this Louisville hotel where Mokara Spa offers therapeutic treatments and rooftop relaxation awaits.
P12,923
P15,206 total
includes taxes & fees
Nov 16 - Nov 17
Omni Louisville Hotel
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.
A steam fountain in a brick alleyway.
A modern bathroom with a shower, a sink, and a large mirror.

2. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
  • Experience a rejuvenating spa escape at this luxury boutique hotel with massage rooms and 24-hour fitness center in downtown Louisville.
P9,676
P11,703 total
includes taxes & fees
Nov 22 - Nov 23
21c Museum Hotel Louisville
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.
A modern hotel room with a large window, a sofa, a red armchair, and a small table.
A balcony with a view of a river, a bridge, and a cityscape.

3. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
  • Riverside sanctuary offers rejuvenating spa treatments, panoramic fitness views, and river-facing balconies for a relaxing urban retreat.
P8,657
P10,186 total
includes taxes & fees
Nov 8 - Nov 9
Galt House Hotel Trademark Collection by Wyndham
A treatment room with a massage table, a desk with a computer, and a large mirror.
A poolside area with lounge chairs and a towel with a monogram.
A large, multi-story hotel with a prominent dome and arched windows, featuring a well-lit entrance and landscaped gardens.
A golf course with a flag, a sand bunker, and a building in the background.

4. Belterra Casino Resort

Belterra Casino Resort
Florence
  • Experience soothing river views and rejuvenating spa treatments at this hotel with indoor and outdoor pools.
P7,107
P8,743 total
includes taxes & fees
Nov 15 - Nov 16
Belterra Casino Resort
A restaurant with round tables, chairs, chandeliers, and a bar area.
A spacious lobby with a geometric chandelier, a reception desk, and a red accent wall.
A hot tub with a pool, indoor seating area, and a view of the pool.
A casino with multiple gaming tables and slot machines, a red carpet, and ornate chandeliers.

5. Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination

Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
Elizabeth
  • Refresh your spirit at this riverfront hotel with daily spa treatments and couples rooms, where aromatherapy and Ayurvedic therapies await.
P3,849
P5,544 total
includes taxes & fees
Nov 24 - Nov 25
Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
A hotel lobby with a chandelier, wooden railings, a reception desk, and a large arched doorway.
A spacious indoor area with a staircase, a vending machine, and a business center sign.
A conference room with multiple tables and chairs, a flat-screen TV mounted on the wall, and a large window with blinds.
An indoor swimming pool with clear water, surrounded by lounge chairs and a small seating area.

6. Quality Inn Seymour I-65

Quality Inn Seymour I-65
Seymour
  • Revitalize your body and spirit in this tranquil hotel featuring a full-service daily spa, indoor pool, and 24-hour fitness center.
P5,135
P5,751 total
includes taxes & fees
Nov 24 - Nov 25
Quality Inn Seymour I-65
A rustic bar area with a wooden bar counter, stools, and a variety of bottles and glasses.
A cozy room with a wooden wall, a sofa, and a dining table.
A porch with white rocking chairs and a table, a window with blinds, and a view of a green landscape.
A living room with a sofa, coffee table, and a television mounted on the wall.

7. Pillow and Paddock B&B

Pillow and Paddock B&B
La Grange
  • Relax in a cozy bed and breakfast retreat with a steamy hot tub, rejuvenating spa services, and a peaceful garden sanctuary.
P21,192
P23,362 total
includes taxes & fees
Oct 27 - Oct 28
Pillow and Paddock B&B
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Choose what matters most at spa hotels in Southern Indiana

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Southern Indiana Hotel Reviews

Drury Inn & Suites Evansville East

Drury Inn & Suites Evansville East

10/10 Excellent
"Rooms were very clean and spacious, best out of all were the staff members, very polite, helpful, great customer service, very attentive to needs and comfort."
Edward W 3-night trip
Posted 7 hours ago
Drury Inn & Suites Evansville East
Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

10/10 Excellent
"We’ve been in probably 15 medium-priced hotels on this vacation. This was BY FAR the best. Breakfast was phenomenal!! And it was the little things—better cereal variety, better granola, better sausage and eggs ( not the premade scrambled)"
Joseph 1-night trip
Posted 8 hours ago
Hampton Inn New Albany Louisville West
Hampton Inn Evansville/Airport

Hampton Inn Evansville/Airport

10/10 Excellent
"H"
robert 1-night trip
Posted 5 days ago
Hampton Inn Evansville/Airport
Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North

10/10 Excellent
"remodeled recently. very clean. nice. comfy bed..at least for us. quiet.. but we were at end of the hall. room had plenty of space. nice long bathroom counter for toiletries etc. that was outside of tub and potty area. plenty of choices for breakfast. employees friendly. would definitely stay again!!"
Marilyn 1-night trip
Posted 12 days ago
Ramada by Wyndham Sellersburg/Louisville North

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