Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀

South San Francisco Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Jan 9 - Jan 11
In two months
Feb 20 - Feb 22
In three months
Mar 20 - Mar 22
In four months
Apr 17 - Apr 19

Our top choices for South San Francisco vacation rentals

View from room
Coral Reef Inn & Suites

Aparthotel in East End

Coral Reef Inn & Suites
2.5 star property
6.8 out of 10, (2879)
"The staff was cooperative and patient. "
United States
Phillip
The price is P5,187
P5,913 total
includes taxes & fees
Dec 29 - Dec 30
Coral Reef Inn & Suites
Interior
New 2BR Home w Parking Laundry in 580-80

Vacation Home in Richmond Annex

New 2BR Home w Parking Laundry in 580-80
2.0 star property
7.4 out of 10, Good, (6)
"This was a great stay over all. Great communication and very fast response. Place was exactly how the online photos looked. Only minor thing was the couch had miscellaneous food and trash debris in the cracks. Will definitely recommend."
United States
Miguel
New 2BR Home w Parking Laundry in 580-80
Private kitchen
Comfy 2BR 1Bath Apartment near HWY580-80

Apartment in Richmond Annex

Comfy 2BR 1Bath Apartment near HWY580-80
3.0 star property
7.6 out of 10, Good, (4)
"Everything good thank you "
United States
guillermo
Comfy 2BR 1Bath Apartment near HWY580-80
Garden
Charming 2BR Ocean Getaway in Pacifica

Apartment in Westview

Charming 2BR Ocean Getaway in Pacifica
2.0 star property
9.0 out of 10, Wonderful, (4)
"it was clean and quiet. "
United States
Nader
The price is P6,815
P18,166 total
includes taxes & fees
Dec 29 - Dec 30
Charming 2BR Ocean Getaway in Pacifica
Exterior
Mid Century Garden View Home Parking

Vacation Home in East San Mateo

Mid Century Garden View Home Parking
2.0 star property
8.8 out of 10, Excellent, (3)
"This is a very clean comfortable property! "
United States
Serena
The price is P9,987
P23,257 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Mid Century Garden View Home Parking
Private kitchen
Stunning 2 Bedroom 1 Bath Home near BART

Vacation Home in Daly City

Stunning 2 Bedroom 1 Bath Home near BART
3.0 star property
10.0 out of 10, Exceptional, (1)
The price is P8,342
P18,388 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Stunning 2 Bedroom 1 Bath Home near BART
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top South San Francisco Hotel Reviews

Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta Select San Francisco Airport Oyster Point Waterfront

10/10 Excellent
"Clean room. New hotel"
David 1-night trip
Posted 1 day ago
Sonesta Select San Francisco Airport Oyster Point Waterfront

Find out more about South San Francisco

Search for holiday rentals in South San Francisco on Expedia! You can easily find your home rentals, villas, holiday apartments in South San Francisco using one of the methods below:

  • View our selection of featured holiday rentals in South San Francisco
  • Use the map to find apartments and other holiday homes in the South San Francisco neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in South San Francisco while they last

Look no further and take a look at our great range of rental properties in South San Francisco!

Frequently asked questions

Can I find vacation rentals in South San Francisco?

Yes, we offer vacation rentals in South San Francisco close to See's Candies, or you can select a more remote option if you want a relaxing stay. Tourists like the array of shops and top-notch restaurants in South San Francisco. While you're here, grab a bite or have a drink at the cafes.

What are some of the best vacation rentals in South San Francisco?

Large and Cozy Home 2BD 2BA Near SF: You might want to consider this vacation home rental near South San Francisco, which comes with WiFi so you can feel at home during your trip.

How many vacation rentals are there in South San Francisco?

Choose from 31 Expedia vacation rentals in South San Francisco for a memorable vacation.

What can I see and do in South San Francisco?

Family-friendly attractions include See's Candies and K1 Speed San Francisco, whereas San Francisco Bay and Santa Cruz Mountains are a couple of great spots to enjoy the outdoors. You’ll find favorite places to visit like Oracle Park and Pier 39 in the larger area.

What are vacation rentals like in South San Francisco?

Vacation rentals are private properties you can reserve for a short or long stay in South San Francisco. Vacation rentals feature amenities like kitchens and laundry facilities so you'll be comfy for your stay. If you're concerned about a clean environment, vacation rentals can provide a sense of security away from shared hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a popular option for family gatherings.