Photo by Alexandra Heatwole

Hotels near Six Mile Cypress Slough Preserve

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 22 - Dec 23
Tomorrow
Dec 23 - Dec 24
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Six Mile Cypress Slough Preserve hotels

Free continental breakfast on weekdays
Hampton Inn & Suites Fort Myers - Colonial Blvd

Hampton Inn & Suites Fort Myers - Colonial Blvd

Hampton Inn & Suites Fort Myers - Colonial Blvd
2.5 star property
3.4 km from Six Mile Cypress Slough Preserve
9.4 out of 10, Exceptional, (1003)
"Nice accommodations in a convenient location for touring the local sights. Staff was very friendly. "
United States
MaryLou
The price is P7,897
P8,805 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Hampton Inn & Suites Fort Myers - Colonial Blvd
BBQ/picnic area
Home2 Suites by Hilton Fort Myers Colonial Blvd

Home2 Suites by Hilton Fort Myers Colonial Blvd

Home2 Suites by Hilton Fort Myers Colonial Blvd
3.0 star property
3.5 km from Six Mile Cypress Slough Preserve
9.4 out of 10, Exceptional, (578)
"The food was great "
United States
Adolph
The price is P7,415
P8,268 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Home2 Suites by Hilton Fort Myers Colonial Blvd
Exterior
Best Western Fort Myers Inn & Suites

Best Western Fort Myers Inn & Suites

Best Western Fort Myers Inn & Suites
2.5 star property
3.5 km from Six Mile Cypress Slough Preserve
8.8 out of 10, Excellent, (1115)
"Good location "
United States
Yaeko
The price is P4,916
P5,481 total
includes taxes & fees
Dec 23 - Dec 24
Best Western Fort Myers Inn & Suites
Lobby
Courtyard by Marriott Fort Myers Cape Coral

Courtyard by Marriott Fort Myers Cape Coral

Courtyard by Marriott Fort Myers Cape Coral
3.0 star property
3.7 km from Six Mile Cypress Slough Preserve
8.2 out of 10, Very Good, (1012)
"Very friendly staff, super comfortable room"
United States
Rocio
The price is P5,940
P6,623 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Courtyard by Marriott Fort Myers Cape Coral
Interior
Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
Daniels Corridor, 6.3 km from Six Mile Cypress Slough Preserve
9.6 out of 10, Exceptional, (1001)
"Great stress-free stay"
United States
Kelly
The price is P6,929
P7,726 total
includes taxes & fees
Dec 24 - Dec 25
Holiday Inn Express & Suites Fort Myers Airport by IHG
Indoor pool
Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport
2.5 star property
Daniels Corridor, 4.6 km from Six Mile Cypress Slough Preserve
8.6 out of 10, Excellent, (1124)
"Great staff"
United States
Alison
The price is P5,232
P5,834 total
includes taxes & fees
Dec 25 - Dec 26
Comfort Inn & Suites Fort Myers Airport
Lobby
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
2.0 star property
Daniels Corridor, 4.6 km from Six Mile Cypress Slough Preserve
8.0 out of 10, Very Good, (1509)
"Nice and beautiful place to stay "
United States
Maguenne
The price is P4,387
P4,891 total
includes taxes & fees
Dec 23 - Dec 24
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Lobby lounge
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
Villas, 6.1 km from Six Mile Cypress Slough Preserve
8.6 out of 10, Excellent, (789)
"Clean room and very nice staff "
United States
Michael
The price is P5,049
P5,629 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
Desk, iron/ironing board, free WiFi, bed sheets
SpringHill Suites by Marriott Fort Myers Airport

SpringHill Suites by Marriott Fort Myers Airport

SpringHill Suites by Marriott Fort Myers Airport
3.0 star property
Daniels Corridor, 3.8 km from Six Mile Cypress Slough Preserve
8.6 out of 10, Excellent, (1002)
"Great place to stay, clean, safe, felt like home."
United States
Bradley
The price is P7,437
P8,292 total
includes taxes & fees
Dec 26 - Dec 27
SpringHill Suites by Marriott Fort Myers Airport
Terrace/patio
Residence Inn by Marriott Fort Myers

Residence Inn by Marriott Fort Myers

Residence Inn by Marriott Fort Myers
3.0 star property
3.7 km from Six Mile Cypress Slough Preserve
8.8 out of 10, Excellent, (305)
"Great value and large clean room. Love it"
United States
Vance
The price is P7,437
P8,292 total
includes taxes & fees
Dec 26 - Dec 27
Residence Inn by Marriott Fort Myers
Free daily buffet breakfast
Hampton Inn Fort Myers-Airport & I-75

Hampton Inn Fort Myers-Airport & I-75

Hampton Inn Fort Myers-Airport & I-75
3.5 star property
Daniels Corridor, 3.7 km from Six Mile Cypress Slough Preserve
9.0 out of 10, Wonderful, (1002)
"Clean room, nice staff and great breakfast!"
United States
Gina
The price is P7,424
P8,278 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Hampton Inn Fort Myers-Airport & I-75
Bar (on property)
Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
Villas, 5.2 km from Six Mile Cypress Slough Preserve
8.8 out of 10, Excellent, (1008)
"Great hotel and location and good value. "
United States
Amy
The price is P7,415
P8,268 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Doubletree by Hilton Fort Myers at Bell Tower Shops
Exterior
Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers
3.0 star property
Villas, 5.1 km from Six Mile Cypress Slough Preserve
9.2 out of 10, Wonderful, (1003)
"Great stay. Excellent staff cleanliness and breakfast was best at any hotel stay"
United States
chad
The price is P7,875
P8,780 total
includes taxes & fees
Dec 24 - Dec 25
Homewood Suites by Hilton - Fort Myers
BBQ/picnic area
Towneplace Suites By Marriott Fort Myers Southeast

Towneplace Suites By Marriott Fort Myers Southeast

Towneplace Suites By Marriott Fort Myers Southeast
3.0 star property
4.5 km from Six Mile Cypress Slough Preserve
9.4 out of 10, Exceptional, (49)
"Excellent services and location very clean and comfortable beds "
United States
Rolando
The price is P8,162
P9,101 total
includes taxes & fees
Dec 24 - Dec 25
Towneplace Suites By Marriott Fort Myers Southeast
Lobby
Quality Suites Fort Myers I-75

Quality Suites Fort Myers I-75

Quality Suites Fort Myers I-75
2.5 star property
Daniels Corridor, 4 km from Six Mile Cypress Slough Preserve
8.0 out of 10, Very Good, (1003)
"Clean place comfy beds "
United States
Todd
The price is P5,523
P6,158 total
includes taxes & fees
Dec 29 - Dec 30
Quality Suites Fort Myers I-75
Lobby
Extended Stay America Premier Suites - Fort Myers - Airport

Extended Stay America Premier Suites - Fort Myers - Airport

Extended Stay America Premier Suites - Fort Myers - Airport
2.5 star property
Daniels Corridor, 5.6 km from Six Mile Cypress Slough Preserve
8.8 out of 10, Excellent, (781)
"Amazing stay"
United States
JAVIER
The price is P4,545
P5,067 total
includes taxes & fees
Dec 23 - Dec 24
Extended Stay America Premier Suites - Fort Myers - Airport
Free buffet breakfast
Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG

Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG

Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG
2.5 star property
5.2 km from Six Mile Cypress Slough Preserve
8.4 out of 10, Very Good, (1011)
"Overall great one night stay from flying into RSW. "
United States
Michael
The price is P6,694
P7,464 total
includes taxes & fees
Dec 28 - Dec 29
Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG
Terrace/patio
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
Villas, 6.3 km from Six Mile Cypress Slough Preserve
8.8 out of 10, Excellent, (1002)
"Great amenities, pool and spa, clean room, beautiful lobby and good on site restaurant "
United States
Aleksandar
The price is P6,171
P6,880 total
includes taxes & fees
Dec 28 - Dec 29
Hilton Garden Inn Ft Myers
Reception
Americas Best Value Inn Ft. Myers

Americas Best Value Inn Ft. Myers

Americas Best Value Inn Ft. Myers
3.0 star property
4.8 km from Six Mile Cypress Slough Preserve
7.6 out of 10, Good, (1126)
"Loved it. The staff was great rooms were clean. "
United States
Austin
The price is P4,024
P4,487 total
includes taxes & fees
Dec 23 - Dec 24
Americas Best Value Inn Ft. Myers
Coffee service
Travelodge by Wyndham Fort Myers Airport

Travelodge by Wyndham Fort Myers Airport

Travelodge by Wyndham Fort Myers Airport
2.0 star property
Daniels Corridor, 4 km from Six Mile Cypress Slough Preserve
7.4 out of 10, Good, (1003)
"Rooms are very clean, good value and friendly staff. I’ve stayed here many times."
United States
Mary
The price is P4,169
P4,649 total
includes taxes & fees
Dec 23 - Dec 24
Travelodge by Wyndham Fort Myers Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Six Mile Cypress Slough Preserve Hotel Reviews

Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG

Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG

10/10 Excellent
"The room is clean and stuff is nice. "
FangJun 1-night trip
Posted 12 hours ago
Holiday Inn Express Hotel & Suites Fort Myers East - The Forum by IHG

Hotels near other Six Mile Cypress Slough Preserve attractions

Bell Tower Shops

4.2/5 (472 reviews)
You can search for that perfect souvenir at Bell Tower Shops during your visit to Fort Myers. Discover the beautiful sunsets and top-notch restaurants in this family-friendly area.
See properties

Brookshire Bath and Tennis Club

Catch an event at Brookshire Bath and Tennis Club during your trip to Fort Myers.
See properties

Frequently asked questions

What's the area like around Six Mile Cypress Slough Preserve?
Six Mile Cypress Slough Preserve is located in a family-friendly area of Fort Myers known for its beautiful beaches and bird watching. If you're looking for a convenient place to stay, check out the 32 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Six Mile Cypress Slough Preserve?
Courtyard by Marriott Fort Myers Cape Coral is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. It's located 2.3 mi (3.7 km) from Six Mile Cypress Slough Preserve. Other good choices within 5 miles include Hampton Inn & Suites Fort Myers - Colonial Blvd and Home2 Suites by Hilton Fort Myers Colonial Blvd.
How many hotels will I find close to Six Mile Cypress Slough Preserve?
Expedia has 32 hotels and other accommodations within a mile from Six Mile Cypress Slough Preserve.
If I need to cancel the hotel reservation for my stay near Six Mile Cypress Slough Preserve, will I receive a refund?
Yes! The majority of hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to review the best deals near Six Mile Cypress Slough Preserve.
What can I see and do near Six Mile Cypress Slough Preserve?
You can enjoy live performances at Barbara B Mann Hall and Broadway Palm Dinner Theatre. You might spend a leisurely day outdoors at Lakes Regional Park and Dunbar Park. Calusa Nature Center and Planetarium, Railroad Museum of South Florida, and Castle Golf are fun stops for the whole family while you're in town.