Sedgewickville Hotels

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Our top choices for Sedgewickville hotels

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (103)
"It was a nice stay"
United States
Douglas
The price is P5,249
P5,974 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Tru By Hilton Cape Girardeau

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (84)
"Cute room, great food, fun soda fountain and friendly owners! Will return! "
United States
Leslie
EC Reed's Mercantile and Hotel

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (686)
"Overall was wonderful customer service and breakfast"
United States
Stephanie
The price is P3,382
P3,816 total
includes taxes & fees
Dec 30 - Dec 31
Quality Inn Cape Girardeau North

Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (425)
"The staff member Tim was very friendly and nice. "
United States
Julie
The price is P4,122
P4,462 total
includes taxes & fees
Jan 21 - Jan 22, 2026
Town House Inn

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very Good, (740)
"Room was clean and affordable for one night. The morning person could have been more attentive to me being there for breakfast. No greeting at all and sat on her phone. I was the only one down in the breakfast area. Be more aware of her surroundings while working alone. "
United States
Lori
The price is P4,686
P5,071 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Suites Jackson-Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (674)
"Great place "
United States
GUY
The price is P4,941
P5,348 total
includes taxes & fees
Jan 7 - Jan 8, 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (297)
"Room was not exactly smelling nice, but room was clean and comfortable. The lodge was close to expressway and shopping. Staff was very friendly. I would stay there again."
United States
Steve
The price is P4,568
P4,990 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Madison Inn Lodge

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1010)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is P4,873
P5,152 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Drury Inn & Suites Jackson MO

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (543)
"lean, updated rooms, friendly staff and great breakfast."
United States
Linda
The price is P5,109
P5,848 total
includes taxes & fees
Dec 28 - Dec 29
Holiday Inn Express & Suites Perryville by IHG

Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.2 out of 10, Wonderful, (17)
"Great place to stay! "
United States
Eric
Urban Lofts

Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.4 out of 10, Very Good, (941)
"My girlfriend found hair and leaves in the tub of our room. This is after we checked in and it was only for one night."
United States
Timothy
The price is P3,893
P4,457 total
includes taxes & fees
Dec 30 - Dec 31
Super 8 by Wyndham Perryville

Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville
2.0 star property
Perryville
6.8 out of 10, (415)
"Was a nice place."
United States
Lesliee
The price is P3,644
P4,171 total
includes taxes & fees
Dec 28 - Dec 29
Days Inn by Wyndham Perryville

Quality Inn Perryville I-55

Quality Inn Perryville I-55
2.5 star property
Perryville
6.6 out of 10, (124)
"Nice place would recommend Mary Jane’s if you’re looking for good food "
United States
Andrew
The price is P4,072
P4,662 total
includes taxes & fees
Dec 30 - Dec 31
Quality Inn Perryville I-55
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sedgewickville Hotel Reviews

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Frequently asked questions

What's the best place for a stay in Sedgewickville?
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, located 7.2 mi (11.5 km) from the heart of Sedgewickville, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Drury Inn & Suites Jackson MO and Quality Inn Cape Girardeau North. See all available top hotels, or vacation rentals in Sedgewickville.
If I need to cancel my hotel reservation in Sedgewickville, will I receive a refund?
Yes! Most room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sedgewickville.
How is it to stay in Sedgewickville?
Those traveling to Sedgewickville are sure to enjoy the sights to see and things to do. There are 82 hotels and other accommodations in the surrounding area. Find out more about Sedgewickville.
What are the top places to visit in Sedgewickville?
Places to visit in the wider area include Perryville Country Club, National Shrine of Our Lady of the Miraculous Medal, and Bollinger Mill State Historic Site. You'll also find Saint Marys Lake and Missouri's National Veterans Memorial in the area. Check out what more to see and do in Expedia's Sedgewickville guide.
What's the weather like in Sedgewickville?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Sedgewickville is 59 inches.

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