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Oct 4 - Oct 5
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Oct 5 - Oct 6
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Oct 9 - Oct 11
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Oct 16 - Oct 18

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Our top choices for Santana hotels

A clear, shallow water body surrounded by dense mangrove trees under a bright blue sky.
A person standing on a concrete staircase in a building with white walls and a wooden door.
A clear turquoise sea with a sandy beach and mangrove trees in the background.
A spacious indoor area with a high ceiling, wooden chairs, and potted plants.

1. Parguera Plaza Hotel - Adults Only

Parguera Plaza Hotel - Adults Only
Lajas
United States
Carlos
P8,992
P9,801 total
includes taxes & fees
Oct 5 - Oct 6
Parguera Plaza Hotel - Adults Only
A modern building with a bridge over a small pond, surrounded by lush greenery and palm trees.
A water feature with a waterfall and a bird sculpture in a landscaped area.
A spacious lobby with a classic car exhibit, modern furniture, and large windows offering natural light.
A spacious lobby with large windows, blue seating, and a modern design.

2. Costa Bahia Hotel & Convention Center

Costa Bahia Hotel & Convention Center
Guayanilla
United States
Angelica
P7,528
P9,025 total
includes taxes & fees
Oct 5 - Oct 6
Costa Bahia Hotel & Convention Center
A swimming pool with a stone border, a thatched-roof structure, and a view of green hills in the background.
A hotel entrance with a green wall, a carousel, and a reception area.
A terrace with wicker furniture, a white railing, and a 'LOVE' sign.
A modern hotel room with a large bed, a bedside table, a TV mounted on the wall, and a small desk with a chair.

3. Hotel Vista Verde

Hotel Vista Verde
Yauco
United States
Amneris
P7,318
P8,289 total
includes taxes & fees
Oct 11 - Oct 12
Hotel Vista Verde
A coastal view with a white gazebo, palm trees, and a boat on the water.
A pool area with clear blue water, white lounge chairs, and a water feature.
A waterfront hotel with a pool, palm trees, and a boat docked nearby.
A white gazebo with a view of the ocean and palm trees.

4. Parador Villa Parguera

Parador Villa Parguera
Lajas
United States
Maria E.
P8,773
P9,387 total
includes taxes & fees
Oct 5 - Oct 6
Parador Villa Parguera
A clear blue sea with boats and people in the water.
A swimming pool with a tiled deck, surrounded by a covered patio area with outdoor furniture.
A hallway with a potted plant, a fire extinguisher, and a window.
A couple toasting with drinks at a wooden bar with a mural in the background.

5. Turtle Bay Inn

Turtle Bay Inn
Lajas
United States
Hugo
P8,384
P8,971 total
includes taxes & fees
Oct 11 - Oct 12
Turtle Bay Inn
A pool area with a hammock and lounge chairs, a covered deck, and a view of the ocean.
A modern hotel room with a bed, a TV mounted on the wall, a window with curtains, and a ceiling fan.
A modern reception area with a wooden reception desk, a hanging light fixture, and yellow chairs.
A bedroom with a large bed, a TV, a desk, and a balcony view.

6. La Jamaca

La Jamaca
Lajas
United States
Damaris
P8,726
P9,987 total
includes taxes & fees
Oct 6 - Oct 7
La Jamaca
A hotel with a pool, palm trees, and a well-lit balcony area.
A multi-story building with a balcony, a staircase, and a playground in the background.
A multi-story building with a central courtyard, a fountain, and a pool.
A two-story building with a balcony overlooking a body of water.

7. Parador Guánica 1929

Parador Guánica 1929
Guanica
United States
Ramón
P7,853
P8,560 total
includes taxes & fees
Oct 7 - Oct 8
Parador Guánica 1929
A beachside hut with a thatched roof, a hammock, and a view of the sea.
A pool area with lounge chairs, a palm tree, and a view of the ocean.
A wedding ceremony on a grassy lawn with tables and chairs, palm trees, and a gazebo.
A modern bedroom with a large bed, a desk, and a balcony.

8. Copamarina Beach Resort & Spa

Copamarina Beach Resort & Spa
Guanica
United States
Angel Fernando
P12,126
P15,861 total
includes taxes & fees
Nov 2 - Nov 3
Copamarina Beach Resort & Spa
An indoor swimming pool with a hammock, lounge chairs, and potted plants.
A marina with boats docked, a building with a sign for boat rental, and a moon in the sky.
A tropical garden with palm trees and a seating area with green chairs.
A room with a white door, a white chair, a blue and white hammock, and a small table.

9. Nautilus By La Jamaca Hotels-Downtown La Parguera

Nautilus By La Jamaca Hotels-Downtown La Parguera
Lajas
United States
Carlos
P8,351
P9,559 total
includes taxes & fees
Oct 24 - Oct 25
Nautilus By La Jamaca Hotels-Downtown La Parguera
A double wooden door with intricate ironwork.
A staircase with red carpeted steps, a chandelier, and a golden angel decoration.
A bedroom with a large bed, a smaller bed, and a sofa. The room has patterned tile flooring and a curved ceiling.
A covered outdoor seating area with blue metal chairs and a table, surrounded by potted plants and a decorative wall.

10. Hotel Colonial

Hotel Colonial
Cárcel
United States
Enelida
P5,289
P5,659 total
includes taxes & fees
Oct 5 - Oct 6
Hotel Colonial
A hotel entrance with a sign reading "Hotel Maya Plaza" and an "EXIT" sign above the door.
A modern lobby with orange seating, a round coffee table, and a wall-mounted clock.
A modern restaurant with a central counter, seating area, and a mural on the wall.
A covered outdoor seating area with tables and chairs, a pergola overhead, and a view of the street.

11. Hotel Mayaguez Plaza, BW Signature Collection

Hotel Mayaguez Plaza, BW Signature Collection
Cárcel
United States
Miguel
P6,594
P7,187 total
includes taxes & fees
Oct 11 - Oct 12
Hotel Mayaguez Plaza, BW Signature Collection
An indoor swimming pool with a tiled edge, surrounded by lounge chairs and potted plants.
A reception area with a neon sign reading "TRYP Mayaguez," two black reception desks, wooden paneling, and a fire alarm on the wall.
A hotel room with two beds, a large mirror, a painting, and a wooden headboard.
A building with a green facade, numbered 1866, featuring outdoor seating with chairs and tables, a gated entrance, and a sign for 'casa abu' restaurant.

12. Tryp by Wyndham Mayaguez

Tryp by Wyndham Mayaguez
Cárcel
United States
Israel
P8,445
P9,205 total
includes taxes & fees
Oct 25 - Oct 26
Tryp by Wyndham Mayaguez
A set of outdoor brick steps leading up to a covered area with a concrete floor.
A lobby with a sofa, two armchairs, a coffee table, and a patterned curtain.
A reception area with a wooden reception desk, a brown sofa with patterned cushions, and a poster on the wall.
A building with a symmetrical facade, multiple columns, and a central entrance.

13. Hostal Universitario

Hostal Universitario
San German
United States
Brunilda
P4,379
P4,773 total
includes taxes & fees
Oct 12 - Oct 13
Hostal Universitario
A cozy wooden cabin interior with a hammock, a small table, and a potted plant.
A cozy bedroom with a wooden ceiling, a bed with white bedding, a nightstand, and a window with curtains.
A person sitting on a hot tub with a tropical garden view.
A hot tub on a wooden deck with a view of lush greenery.

14. Hacienda Tres Casitas

Hacienda Tres Casitas
Cabo Rojo
United States
Michelle
P6,530
P11,003 total
includes taxes & fees
Oct 12 - Oct 13
Hacienda Tres Casitas
A pool area with a water fountain, lounge chairs, and umbrellas.
A hotel room with a bed, desk, TV, and a desk lamp.
A modern hotel with a white facade, multiple balconies, and lush greenery including palm trees.
A spacious lobby with a casino, seating areas, and a reception desk.

15. Holiday Inn Mayaguez and Tropical Casino by IHG

Holiday Inn Mayaguez and Tropical Casino by IHG
Mayagüez
United States
Luz
P9,758
P10,832 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Mayaguez and Tropical Casino by IHG
A modern hotel room with two beds, a desk, and a flat-screen TV.
A spacious indoor area with white chairs and tables, a reception desk, and a modern ceiling design.
A multi-story building with balconies, outdoor seating, and a staircase.
A multi-story hotel with a swimming pool, outdoor seating, and a balcony with a glass railing.

16. Douglas Highway Hotel

Douglas Highway Hotel
Cabo Rojo
United States
Roberto
P7,431
P8,100 total
includes taxes & fees
Oct 5 - Oct 6
Douglas Highway Hotel
A nighttime pool area with lounge chairs and palm trees, surrounded by multi-story buildings with balconies.
A pathway lined with palm trees leading to a building with balconies and a yellow awning.
A bar area with a 'DonQ' sign, various liquor bottles, and seating with chairs and tables.
A balcony with a view of a lush landscape and palm trees.

17. Aquarius Vacation Club at Boqueron Beach Resort

Aquarius Vacation Club at Boqueron Beach Resort
Cabo Rojo
United States
Ana Laura
P7,499
P8,506 total
includes taxes & fees
Oct 5 - Oct 6
Aquarius Vacation Club at Boqueron Beach Resort
A swimming pool with clear blue water, a tiled deck, and white lounge chairs.
A banquet hall with round tables, chairs, and draped fabric on the ceiling.
A neatly arranged hotel room with a bed, a bedside table with a lamp, a clock, and a small table with a remote control.
A dining table with a plate of food, a glass of drink, and a chair.

18. Mi Tierra

Mi Tierra
Cabo Rojo
United States
Jose Juan
P6,756
P7,701 total
includes taxes & fees
Oct 5 - Oct 6
Mi Tierra
A modern bathroom with a glass-enclosed shower, wooden flooring, a bed with a striped bedspread, and a small table with a coffee maker.
A room with a white wooden slatted wall, a black sofa with patterned cushions, and a staircase with blue railings.
A swimming pool with clear blue water, surrounded by a blue fence with plants and flowers.
A modern bathroom with a glass shower enclosure, a white sink, and a toilet.

19. Parguera Beach Club Hotel

Parguera Beach Club Hotel
Lajas
United States
Richard
P5,010
P8,276 total
includes taxes & fees
Oct 7 - Oct 8
Parguera Beach Club Hotel
A residential property with a swimming pool, outdoor seating, and a covered patio area.
Exterior
Room
A two-story building with a balcony, a staircase, and a small garden area.

20. Mermaid Cove

Mermaid Cove
La Parguerra
United States
Maria
P7,037
P11,761 total
includes taxes & fees
Nov 2 - Nov 3
Mermaid Cove
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Learn more about Santana

Venture to sights like Bosque Estatal de Maricao as you discover the local area in Santana.

See all hotels in Santana
A stone archway with a metal gate.
Photo by Norberto Moctezuma Gomez

Top Santana Hotel Reviews

Tryp by Wyndham Mayaguez

Tryp by Wyndham Mayaguez

10/10 Excellent
"From the moment we checked in, the outstanding customer service set the tone for our entire trip. The front desk staff went completely above and beyond, greeting us by name, offering great local recommendations, and ensuring we had everything we needed for a comfortable stay. Every single employee we encountered—from housekeeping to the lobby team—was incredibly warm, attentive, and professional. The property itself is exceptional. Both the guest rooms and the public areas are kept absolutely pristine, with housekeeping doing a meticulous job every day. In addition to being exceptionally clean, the hotel boasts fantastic facilities. The fitness center is well-equipped and modern, the pool area feels like a private oasis."
Marcos 2-night trip
Posted less than an hour ago
Tryp by Wyndham Mayaguez
Hotel Colonial

Hotel Colonial

10/10 Excellent
"El personal muy atento y simpático. La edificación en buenas condiciones y conserva sus características originales. El estacionamiento al cruzar la tranquila calle es satisfactorio. Puedo volver."
Jose A. 1-night trip
Posted 17 hours ago
Hotel Colonial
Parguera Plaza Hotel - Adults Only

Parguera Plaza Hotel - Adults Only

10/10 Excellent
"Excelente!"
Taishnely 1-night trip
Posted 17 hours ago
Parguera Plaza Hotel - Adults Only
Hotel Vista Verde

Hotel Vista Verde

10/10 Excellent
"Todo estubo muy bien!"
Rolando 1-night trip
Posted 22 hours ago
Hotel Vista Verde
Royal Delonix Hotel

Royal Delonix Hotel

10/10 Excellent
"Excelente lugar a buen precio."
Luis 2-night trip
Posted 1 day ago
Royal Delonix Hotel
Copamarina Beach Resort & Spa

Copamarina Beach Resort & Spa

10/10 Excellent
"Absolutely loved it. It was off season."
GABRIELA 1-night trip
Posted 3 days ago
Copamarina Beach Resort & Spa
Rocamar Resort & Restaurant - All Inclusive

Rocamar Resort & Restaurant - All Inclusive

8/10 Good
"The room was clean and has a fridge and microwave, Only thing was a cockroach in the bathroom but thankfully it was dead, The dogs are very cute and sweet however, sometimes heard them barking while we were sleeping which woke us up a few times during our stay. The food was ok. The staff is very nice and helped us get checked in safely, I would come here again. Its really close to two other beautiful towns."
Chloe 4-night trip
Posted 1 month ago
Rocamar Resort & Restaurant - All Inclusive

More cheap stays in Santana

Hostal Universitario

Hostal Universitario

Carretera 102, km 30.6 San German
P4,379
P4,773 total
Oct 12 - Oct 13
includes taxes & fees
9/10 Wonderful! (223 reviews)
Hostal Universitario
Hacienda Villa Sotomayor

Hacienda Villa Sotomayor

Bo Garzas Adjuntas Adjuntas
P3,991
P4,913 total
Oct 6 - Oct 7
includes taxes & fees
Hacienda Villa Sotomayor
Hotel Colonial

Hotel Colonial

Calle Iglesia 14 Sur Mayagüez
P5,289
P5,659 total
Oct 5 - Oct 6
includes taxes & fees
9.4/10 Exceptional! (1,166 reviews)
Hotel Colonial
I Love Combate Rooms & Suites

I Love Combate Rooms & Suites

Carr 3301 Km 2.8 Cabo Rojo PR
P7,125
P8,077 total
Oct 7 - Oct 8
includes taxes & fees
9.6/10 Exceptional! (60 reviews)
I Love Combate Rooms & Suites
Douglas Highway Hotel

Douglas Highway Hotel

Carr. 100 KM8 Bo. Miradero Cabo Rojo Puerto Rico
P7,431
P8,100 total
Oct 5 - Oct 6
includes taxes & fees
Douglas Highway Hotel
Parador Boquemar

Parador Boquemar

Carr. 101, Calle Gil Bouyet Cabo Rojo
P8,411
P8,999 total
Oct 5 - Oct 6
includes taxes & fees
7.4/10 Good! (778 reviews)
Parador Boquemar

Frequently asked questions

Where is the best place to stay in Santana?
Aquarius Vacation Club at Boqueron Beach Resort, located 14.6 mi (23.5 km) from the heart of Santana, is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are Holiday Inn Mayaguez and Tropical Casino by IHG and Parguera Plaza Hotel - Adults Only. See all available top hotels, or vacation rentals in Santana.
What are some of the best vacation home rentals that Santana has to offer?
Blue House Joyuda: This vacation home rental near Santana is located near the beach and has an outdoor pool, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a microwave, and a coffee maker. See all vacation rentals in Santana.
If I need to cancel my hotel reservation in Santana, will I receive a refund?
Yes, you'll find most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santana.
How is it staying in Santana?
Visitors to Santana are sure to find plenty to explore and enjoy. There are 803 hotels and other accommodations in the surrounding area. Find out more about Santana.
What is there to see in Santana?
A favorite place to visit is Bosque Estatal de Maricao. You'll also find Casa Morales and Bioluminescent Bay in the area. Check out what more to see and do in Expedia's Santana guide.
What's the seasonal weather like in Santana?
The hottest months are usually July and August with an average temp of 81°F, while the coldest months are January and February with an average of 76°F. Average annual precipitation for Santana is 33 inches.

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