A modern building with a unique triangular roof and a central spire.

Santa Lucia Hotels near Syracuse

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Check prices for these dates

This weekend
Aug 7 - Aug 9
Next weekend
Aug 14 - Aug 16

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Our top choices for Santa Lucia hotels

Rooftop terrace

1. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (289 reviews)
"Beautiful hotel with good amenities"
Canada
Alessia
The price is P11,425
P13,270 total
includes taxes & fees
Aug 9 - Aug 10
Caportigia Boutique Hotel
Porch

2. Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (386 reviews)
"This was my favorite stay in Sicily! I love the elevator and the staff were really nice and accommodating. I also want to point out the excellent AC inside the room. I would only suggest a bottle of water inside the room and a personal tea/ coffee station."
United States
Diane
The price is P5,426
P6,186 total
includes taxes & fees
Aug 8 - Aug 9
Piccolo Hotel Casa Mia
Front of property

3. Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (687 reviews)
"This accommodation was very comfortable and I would highly recommend it."
Australia
Janet
The price is P8,789
P10,020 total
includes taxes & fees
Aug 29 - Aug 30
Grande Albergo Alfeo
Coffee/tea maker, electric kettle

4. Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (283 reviews)
"A really nice room, the bed was extremely comfortable and the staff were very friendly."
United Kingdom
Michael
The price is P5,196
P5,924 total
includes taxes & fees
Aug 26 - Aug 27
Nostos rooms & Apartments
Minibar, in-room safe, desk, soundproofing

5. Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (74 reviews)
"The room appeared to be recently remodeled and was very modern. Of the 4 hotels that we stayed at on this trip, the bed/pillows were the most comfortable. Great view of the marina from our room balcony and public parking (free) was relatively easy. "
United States
Michael
The price is P7,276
P8,295 total
includes taxes & fees
Sep 5 - Sep 6
Lakkios
Balcony

6. B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (88 reviews)
"Great location and comfortable stay!"
United States
Rosa
The price is P5,361
P6,112 total
includes taxes & fees
Sep 5 - Sep 6
B&B Nike
Soundproofing, WiFi (free)

7. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (43 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
The price is P10,004
P11,404 total
includes taxes & fees
Aug 7 - Aug 8
Hotel Palazzo Cavalieri
WiFi (free)

8. B&B L'INFIORESCENZA

B&B L'INFIORESCENZA
Santa Lucia
8.0 out of 10, Very Good, (2 reviews)
"Camera pulita cuscini scomodi pareti sottilissime si sente nelle stanze intorno qualsiasi piccolissimo rumore, colazione al bar cappuccino ottimo e paste molto grandi e buone, negozi nelle vicinanze no e distanza da Ortigia 15 minuti a piedi circa."
Italy
Loris
The price is P2,794
P3,990 total
includes taxes & fees
Aug 16 - Aug 17
B&B L'INFIORESCENZA
1 bedroom, down comforters, minibar, in-room safe

9. Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (58 reviews)
"Wonderful property, excellent staff and the most amazing view from the apartment"
Australia
Anthony
The price is P16,487
P18,838 total
includes taxes & fees
Aug 7 - Aug 8
Re Dionisio Luxury Suites
Breakfast area

10. Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (130 reviews)
"Amazing stay. Beautiful views and everyone was very friendly. "
United States
Anna
The price is P15,738
P18,014 total
includes taxes & fees
Aug 8 - Aug 9
Giuggiulena Villa
Lobby lounge

11. Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (17 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is P6,966
P7,941 total
includes taxes & fees
Aug 31 - Sep 1
Regina Margherita
View from room

12. Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (124 reviews)
"Very friendly and helpful staff."
United States
David
The price is P7,257
P8,273 total
includes taxes & fees
Aug 29 - Aug 30
Hotel Mediterraneo
In-room safe, desk, soundproofing, iron/ironing board

13. B&B IL MORO

B&B IL MORO
Santa Lucia
The price is P5,561
P7,940 total
includes taxes & fees
Aug 20 - Aug 21
B&B IL MORO
Soundproofing, WiFi (free)

14. Melody rooms

Melody rooms
Santa Lucia
The price is P4,322
P4,927 total
includes taxes & fees
Aug 11 - Aug 12
Melody rooms
Terrace/patio

15. Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (37 reviews)
"Wonderful stay in the center of it all "
United States
lori
The price is P12,316
P14,041 total
includes taxes & fees
Aug 7 - Aug 8
Fortaleza Charme House
In-room safe, soundproofing, iron/ironing board (on request)

16. Isonzo Suites

Isonzo Suites
Santa Lucia
8.8 out of 10, Excellent, (6 reviews)
"."
Italy
Gianluca
The price is P4,420
P7,121 total
includes taxes & fees
Aug 9 - Aug 10
Isonzo Suites
Exterior

17. Populus

Populus
1.0 star property
Santa Lucia
7.8 out of 10, Good, (75 reviews)
"Just stay somewhere else, plain and simple."
United States
Thomas
The price is P5,170
P5,894 total
includes taxes & fees
Sep 1 - Sep 2
Populus
Premium bedding, desk, cribs (surcharge), rollaway beds (surcharge)

18. B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is P5,425
P6,185 total
includes taxes & fees
Aug 30 - Aug 31
B&B Siracusa
View from room

19. Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
9.8 out of 10, Exceptional, (17 reviews)
"Clean, very convenient for exploring Ortigia. Nice continental breakfast."
United States
Mary
The price is P9,533
P10,867 total
includes taxes & fees
Aug 13 - Aug 14
Calafatari B&B
View from room

20. Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (42 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is P4,251
P4,846 total
includes taxes & fees
Sep 2 - Sep 3
Gymnasium
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
View from room
Calafatari B&B
3.0 star property
9.8
Exceptional
17 reviews
View
Breakfast area
Giuggiulena Villa
3.0 star property
10.0
Exceptional
130 reviews
View
Minibar, in-room safe, desk, soundproofing
Lakkios
3.0 star property
9.2
Wonderful
74 reviews
View
Frette Italian sheets, premium bedding, down comforters, desk
Fortuna Guest House
1.0 star property
9.2
Wonderful
19 reviews
View
Soundproofing, WiFi (free)
Hotel Palazzo Cavalieri
4.0 star property
9.0
Wonderful
43 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Teatro dei Pupi and Cathedral of Syracuse while you're in town.

Ancient ruins with a large amphitheater surrounded by trees.
Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Archaeological Park of Neapolis and Greek Theatre of Syracuse.

A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Aerial view of Ortigia, historical centre of the city of Syracuse. Aerial view of Maniace fortress in Ortigia, Sicily, Italy. Sanctuary "Our Lady of Tears" is at the background

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Top Santa Lucia Hotel Reviews

Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

10/10 Excellent
"Absolutely magnificent stay!!!! Surprised no turn down service but otherwise zero complaints!!!"
Annie 4-night trip
Posted 2 days ago
Palazzo Artemide - VRetreats, SLH Collection

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.
Where is the best place to stay in Santa Lucia?
Based on our traveler data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Caportigia Boutique Hotel and Fortaleza Charme House.
How many hotels can I expect to find in Santa Lucia?
Expedia has 312 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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