Santa Lucia Hotels near Syracuse

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Lucia hotels

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (261 reviews)
"Valentina & Malvina"
United States
Andrew
The price is P7,043
P8,436 total
includes taxes & fees
Mar 2 - Mar 3
Caportigia Boutique Hotel

Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (652 reviews)
"The room was nice the location convenient. No view to speak of but centrally located"
Canada
Eric
Grande Albergo Alfeo

Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (40 reviews)
"Nice kitchen area, centrally located."
United States
Richard
Gymnasium

Lakkios

Lakkios
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (63 reviews)
"Nice, central, clean, easy to park, quiet during the night, staff was welcoming, nice breakfast with view - excellent choice!"
Norway
Jon-Kåre
Lakkios

Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (274 reviews)
"Welcoming, room, staff and area around definitely stood out!"
Canada
Aina
The price is P3,756
P4,282 total
includes taxes & fees
Feb 17 - Feb 18
Nostos rooms & Apartments

Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (374 reviews)
"The staff is extremely nice and friendly and you feel welcome. "
Canada
Florentina
Piccolo Hotel Casa Mia

Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (126 reviews)
"Fantastic stay. Made to feel very welcome and what a lovely relaxing place to stay. Evening meal was exceptional. "
United States
Paul
The price is P14,024
P15,988 total
includes taxes & fees
Feb 28 - Mar 1
Giuggiulena Villa

Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (27 reviews)
"Wonderful stay in the center of it all "
United States
lori
The price is P9,128
P10,405 total
includes taxes & fees
Feb 28 - Mar 1
Fortaleza Charme House

Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (57 reviews)
"Spacious room, dated but comfortable."
United States
Kenneth
Re Dionisio Luxury Suites

Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (11 reviews)
"We had a lovely stay. Anna was very welcoming. We had a lovely large clean room and a nice modern bathroom. She went all out for breakfast. "
United States
Carl and Lina
Calafatari B&B

B&B Nike

B&B Nike
Santa Lucia
8.8 out of 10, Excellent, (75 reviews)
"Clean, good location. "
United States
Salvatore
B&B Nike

Isonzo Suites

Isonzo Suites
Santa Lucia
8.4 out of 10, Very Good, (5 reviews)
"."
Italy
Gianluca
The price is P4,015
P6,618 total
includes taxes & fees
Feb 22 - Feb 23
Isonzo Suites

Fortuna Guest House

Fortuna Guest House
1.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (16 reviews)
"The owner was really nice and helpful! Really enjoyed our stay here."
Finland
Kirsi
The price is P5,635
P6,423 total
includes taxes & fees
Feb 17 - Feb 18
Fortuna Guest House

AmaCasa Siracusa

AmaCasa Siracusa
Santa Lucia
10.0 out of 10, Exceptional, (1 review)
"Siamo stati molto bene, la struttura internamente è abbastanza ammodernata e l'accesso è stato"
Italy
Alessandro
The price is P5,635
P6,423 total
includes taxes & fees
Mar 1 - Mar 2
AmaCasa Siracusa

Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
8.8 out of 10, Excellent, (41 reviews)
"Enjoyed our stay, nice comfortable room and bed. Very nice breakfast buffet. Within a quick 5 min walk to Ortigia Island, also walkable to train and bus station. Would stay here again."
United States
Jennifer
The price is P7,823
P8,918 total
includes taxes & fees
Feb 26 - Feb 27
Hotel Palazzo Cavalieri

B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (59 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is P5,009
P5,710 total
includes taxes & fees
Mar 1 - Mar 2
B&B Siracusa

Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (15 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
Regina Margherita

San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.4 out of 10, Exceptional, (3 reviews)
"Stanza molto bella e nuova, ottimi arredi, letto comodo e cuscini comodi, belle tende, bagno bello e pulito, specchio del bagno fantastico con una luce bellissima regolabile a led. Mi sono trovato bene, il personale gentilissimo in particolare la ragazza (Lucia se non ricordo male) super cordiale!"
Italy
Davide Angelo
The price is P6,511
P7,423 total
includes taxes & fees
Mar 1 - Mar 2
San Nicola Rooms Siracusa

Agorà

Agorà
Santa Lucia
10.0 out of 10, Exceptional, (2 reviews)
"Trevligt, rent, bra service. Hade turen att få balkong. "
Sweden
Olof
The price is P5,572
P6,352 total
includes taxes & fees
Feb 17 - Feb 18
Agorà

Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (123 reviews)
"Very friendly and helpful staff."
United States
David
Hotel Mediterraneo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
View from room
Calafatari B&B
3.0 star property
10.0
Exceptional
11 reviews
View
Breakfast area
Giuggiulena Villa
3.0 star property
10.0
Exceptional
126 reviews
View
Rooftop terrace
Caportigia Boutique Hotel
5.0 star property
9.4
Exceptional
261 reviews
View
Front of property
Nostos rooms & Apartments
3.0 star property
9.0
Wonderful
274 reviews
View
Minibar, in-room safe, desk, soundproofing
Lakkios
3.0 star property
9.0
Wonderful
63 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Neapolis

While visiting Neapolis, you might make a stop by sights like Ear of Dionysius and Roman Amphitheatre of Syracuse.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Top Santa Lucia Hotel Reviews

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.
Where is the best place to stay in Santa Lucia?
Based on Expedia customer reviews, Caportigia Boutique Hotel is the highest ranked property in Santa Lucia. This hotel offers a restaurant and free parking. Other top choices in the neighborhood include La casa di Aneupe and Hotel Palazzo Cavalieri.
How many hotels can I expect to find in Santa Lucia?
Expedia has 298 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

Explore a world of travel with Expedia