Santa Isabel Hotels

Located 21.7 mi (34.8 km) from the heart of Santa Isabel, Private Ocean-Front Cabin with private bathroom on San Blas Island is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are San Blas Paradise Private Cabins on Shipwreck Island - meals included and Private Over the Water Cabin on San Blas Island. See all available top hotels, or vacation rentals in Santa Isabel.

Yes! The majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.

For additional details about rescheduling or cancelling your trip to Santa Isabel, go to https://www.expedia.com/service/.

Crowne Plaza Panama Airport is a popular 4-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.4 km) from Tocumen Intl. Airport. Other good options within close proximity to the airport include Riande Aeropuerto Hotel & Casino and Express Inn Panama International Airport Hostel.

Visitors can enjoy all that Santa Isabel has to offer including its parks. There are 44 hotels and other accommodations in the surrounding area. Find out more about Santa Isabel.

Places to visit in the wider area include Chagres National Park, Museum, and Porvenir Museum. Check out what more to see and do in Expedia's Santa Isabel guide.

The hottest months are usually June and September with an average temp of 80°F, while the coldest months are February and March with an average of 78°F. The rainiest months in Santa Isabel are October, August, July, and November, with each month seeing an average of 12 inches of rainfall.