Santa Cruz Vacation Rentals

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Vacation Rentals in Santa Cruz

ESJ Beach Hotel

3.5 star property
Isla Verde
6.8 out of 10, (4261)
"Beautiful stay "
United States
Ebony
The price is P9,969
P12,634 total
includes taxes & fees
Dec 7 - Dec 8
ESJ Beach Hotel

Segovia Studio Units

3.0 star property
Sabana Abajo
8.6 out of 10, Excellent, (729)
"Loved this place. Will come again every time I visit!"
United States
Amarys
Segovia Studio Units

Mare 1562

4.0 star property
Isla Verde
9.2 out of 10, Wonderful, (82)
"Room was very clean and comfortable "
United States
Stanzetta
Mare 1562

APT by DW

4.5 star property
Santurce
9.8 out of 10, Exceptional, (73)
"Clean and comfortable."
United States
Chloe
APT by DW

DUNA by DW

4.5 star property
Santurce
9.6 out of 10, Exceptional, (61)
"Great stay. "
United States
Albany
DUNA by DW

MOOD HAUS by DW - 70's Retro Stays

3.5 star property
Santurce
9.2 out of 10, Wonderful, (73)
"Loved this place! It was very beautiful and the check-in instructions were clear and easy. It was also pretty close to the airport and lots of great restaurants. It had everything you could need during an extended trip - so I wish we could have stayed here longer. I really liked the outside soaking tub. They even left us a bath bomb to use. "
United States
Paige
MOOD HAUS by DW - 70's Retro Stays

RainForest House by Otium

2.5 star property
Ceiba
6.6 out of 10, (8)
"Very clean and very close to the ferry terminal which we took advantage to go to culebra island"
United States
mairelly
The price is P3,477
P6,667 total
includes taxes & fees
Dec 7 - Dec 8
RainForest House by Otium

Casa Parcha

3.5 star property
Naguabo
10.0 out of 10, Exceptional, (32)
"Loved the scenery and the bed was ver comfortable. Quick response was awesome as well. Will definitely come back. "
United States
Aurora
The price is P10,019
P11,604 total
includes taxes & fees
Dec 7 - Dec 8
Casa Parcha

Casa Costera, Isla Verde Beach, Apartments by Marriott Bonvoy

2.5 star property
Isla Verde
9.0 out of 10, Wonderful, (149)
"Spacious, modern and functional apartments. Very helpful staff. Convenient to two excellent beaches. Exceeded my expectations! "
United States
ALAN
The price is P13,127
P14,309 total
includes taxes & fees
Dec 18 - Dec 19
Casa Costera, Isla Verde Beach, Apartments by Marriott Bonvoy

Old San Juan Rentals

3.5 star property
Old San Juan
8.6 out of 10, Excellent, (672)
"We had a wonderful stay. Property is centrally located with walkable distance to restaurants, bars, grocery store, and landmarks. Property was clean and spacious. Host was easy to communicate with and readily available. I would definitely recommend staying here! "
United States
Nayvi
The price is P8,090
P12,192 total
includes taxes & fees
Dec 8 - Dec 9
Old San Juan Rentals

Picuas Village

3.0 star property
Zarzal
7.4 out of 10, Good, (59)
"Tranquil"
United States
Edia
The price is P10,888
P16,070 total
includes taxes & fees
Dec 10 - Dec 11
Picuas Village

ESJ by PMI Puerto Rico

3.5 star property
Isla Verde
7.4 out of 10, Good, (29)
"Very comfortable, great view and clean "
United States
Daniela
The price is P6,011
P11,562 total
includes taxes & fees
Dec 9 - Dec 10
ESJ by PMI Puerto Rico

CARIBBEAN STARS

4.0 star property
Sabana Abajo
The price is P5,952
P6,845 total
includes taxes & fees
Jan 6 - Jan 7, 2026
CARIBBEAN STARS

Mare 1660

4.0 star property
Isla Verde
8.6 out of 10, Excellent, (79)
"Very clean friendly easy to get to the beach my room had a great view definitely would stay there again. "
United States
Desiree
Mare 1660

El Yunque Rainforest

3.5 star property
Naguabo
10.0 out of 10, Exceptional, (42)
"It was great!"
United States
Stacy
The price is P14,969
P17,967 total
includes taxes & fees
Dec 12 - Dec 13
El Yunque Rainforest

MANSION MIRAFLORES

3.0 star property
Santurce
9.2 out of 10, Wonderful, (130)
"If I was in a nice place to enjoy "
United States
Carlos F
The price is P8,009
P10,978 total
includes taxes & fees
Dec 8 - Dec 9
MANSION MIRAFLORES

Posada Colonial Apartments

3.0 star property
Santurce
9.2 out of 10, Wonderful, (273)
"Great customer service! Wonderful hospitality and our trip was amazing thanks to the care & consideration from Christina. "
United States
Tiffiiany
The price is P4,641
P7,618 total
includes taxes & fees
Dec 9 - Dec 10
Posada Colonial Apartments

MARU by DW

4.5 star property
Condado
9.2 out of 10, Wonderful, (15)
"We had stayed at a DW property before and really enjoyed both stays. The accomodations are clean and beautifully decorated and the amenities (especially washer/dryer) were greatly appreciated. It is a wonderful place to come back to after a long day of traveling."
United States
Tina
The price is P10,785
P15,289 total
includes taxes & fees
Dec 7 - Dec 8
MARU by DW

PAZ by DW

4.5 star property
Santurce
9.4 out of 10, Exceptional, (21)
"Amazing hotel "
United States
Victoria
PAZ by DW

VERDE by DW

4.5 star property
Santurce
9.2 out of 10, Wonderful, (29)
"Made our stay very special and peaceful! Perfect area, a lot of amazing food nearby! "
United States
estephanie rascon
VERDE by DW
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

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Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we have vacation rentals near well known points of interest in Santa Cruz, or you can go with a more remote option if you want a relaxing place to stay.

What are some of the best vacation home rentals that Santa Cruz has to offer?

150 Sol by Stay with Bear: This vacation home rental near Santa Cruz is in the historical district and equipped with air-conditioning and Netflix to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a full-sized fridge, a stovetop, and a microwave.

What can I see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Carabali Rainforest Park, or get outside and enjoy nature at El Yunque National Forest. Other popular places to visit in the area include Port of San Juan and Condado Beach.

What are vacation rentals like in Santa Cruz?

Vacation rentals are privately owned accommodations you can stay in for a few days or a quick weekend in Santa Cruz. Vacation rentals feature amenities such as laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about a sanitized environment, vacation rentals can provide a sense of seclusion away from shared hotel elevators and bustling concierge desks while still allowing you to travel. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental an attractive option for a family trip or a small group gathering.