Santa Clara

Panama City

Popular places to visit

Multiplaza Pacific Mall

Multiplaza Pacific Mall

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Cinta Costera

Cinta Costera

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Avenida Balboa

Avenida Balboa

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
Fuerte Amador Resort & Marina

Fuerte Amador Resort & Marina

Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Check out the shops and top-notch restaurants in this vibrant area.

Fuerte Amador Resort & Marina
Panama

Miraflores Locks

Learn about the local history of Ancon with a stop at Miraflores Locks. Visit the casinos and shops in this vibrant area.

Miraflores Locks
Calle 50

Calle 50

You can find out about the history of Panama City with a trip to Calle 50. Discover the area's shops, or seek out its local tours.

Calle 50

Things to do

Slingshot Tour Panama

Slingshot Tour Panama

P6,751
per adult
76% of travellers recommend
Slingshot Tour Panama
Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

P8,666
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

P1,867
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
Panama City Visit an Indian town Embera and waterfall with lunch

Panama City Visit an Indian town Embera and waterfall with lunch

P2,908
per adult
96% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
Panama City Tour and Panama Canal – Miraflores Locks Experience

Panama City Tour and Panama Canal – Miraflores Locks Experience

P2,036
per adult
96% of travellers recommend
Panama City Tour and Panama Canal – Miraflores Locks Experience
The Panama Barcrawl - The OG Crawl

The Panama Barcrawl - The OG Crawl

P3,781
per adult
96% of travellers recommend
The Panama Barcrawl - The OG Crawl
See all activities in Panama City

Top hotels in Santa Clara

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
The price is P6,564 per night from Aug 25 to Aug 26
P6,564
P7,220 total
Aug 25 - Aug 26
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (4,164 reviews)
"Wonderful Staff!"

Reviewed on Aug 16, 2025

Hotel Riu Plaza Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
The price is P4,623 per night from Aug 19 to Aug 20
P4,623
P5,085 total
Aug 19 - Aug 20
includes taxes & fees
Stay at this 4-star spa B&B in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located ...
9/10 Wonderful! (414 reviews)
"Nice hotel, lively lots of tourists/ music movement. convenient 24/7 coffee shop. walking distance from other restaurants/shops and night life"

Reviewed on Aug 15, 2025

Waymore Hotel Spa & Casino
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
The price is P11,244 per night from Sep 16 to Sep 17
P11,244
P11,244 total
Sep 16 - Sep 17
includes taxes & fees
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.2/10 Good! (1,014 reviews)
"Restaurants were always short staffed"

Reviewed on Aug 17, 2025

Dreams Playa Bonita Panama - All Inclusive
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111, Panama City, Panama
The price is P5,907 per night from Aug 24 to Aug 25
P5,907
P6,498 total
Aug 24 - Aug 25
includes taxes & fees
Stay at this 4-star spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
7.6/10 Good! (1,000 reviews)
"The hotel was very nice but we never did have hot water in the bathroom the whole time we were there."

Reviewed on Aug 8, 2025

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is P6,507 per night from Sep 8 to Sep 9
P6,507
P7,157 total
Sep 8 - Sep 9
includes taxes & fees
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (2,187 reviews)
"Very convenient to airport. Great bar, restaurant and pool. Not a destination, but a great place to stay as you are leaving Panama City."

Reviewed on Aug 13, 2025

Crowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundable
The price is P7,229 per night from Aug 31 to Sep 1
P7,229
P7,952 total
Aug 31 - Sep 1
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (926 reviews)
"El hotel es super lindo y el desayuno es muy bueno. La atención también excelente."

Reviewed on Aug 6, 2025

Sheraton Grand Panama
See all 1,514 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Clara

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Juan Diaz

You'll enjoy the restaurants and shopping in Juan Diaz. You might want to make time for a stop at Los Pueblos Commercial Center or Estadio Rommel Fernandez.

Juan Diaz
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Costa del Este

Travelers like the restaurants in Costa del Este, and Atrio Mall is a top attraction you might want to visit.

Costa del Este
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Parque Lefevre

You'll enjoy the restaurants and museums in Parque Lefevre. You might want to make time for a stop at Panama Viejo or National Craft Market.

Parque Lefevre
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San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Francisco
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Bethania

When in Bethania, you can plan a visit to El Dorado Mall and Panama Canal Murals, some noteworthy sights in the nearby area.

Bethania
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Obarrio

Unique features of Obarrio include the casinos and coffeehouses. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio

Santa Clara