Sant'Eustachio Hotels near Rome

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sant'Eustachio hotels

Hotel L'Orologio Roma

Hotel L'Orologio Roma
4.0 star property
Sant'Eustachio
9.6 out of 10, Exceptional, (430)
"Super friendly staff great hotel great location "
Canada
Jack
The price is P14,428
P16,908 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Hotel L'Orologio Roma

Feronia Guest House

Feronia Guest House
Sant'Eustachio
8.4 out of 10, Very Good, (34)
"Clean and spacious room, great location walking distance to plenty of restaurants and relatively close to the Pantheon. "
Australia
Caitlin
Feronia Guest House

VELVET GREY BOUTIQUE HOTEL ROMA

VELVET GREY BOUTIQUE HOTEL ROMA
Sant'Eustachio
9.2 out of 10, Wonderful, (52)
"Room was very clean, quiet, amazing location and friendly, calm staff. I had a lovely stay and highly recommend. "
United States
Sage
The price is P6,790
P8,299 total
includes taxes & fees
Jan 11 - Jan 12, 2026
VELVET GREY BOUTIQUE HOTEL ROMA

The Spanish Suite Campo de Fiori

The Spanish Suite Campo de Fiori
Sant'Eustachio
8.4 out of 10, Very Good, (208)
"Nice area good service on the lobby "
United States
Hector
The price is P5,658
P6,915 total
includes taxes & fees
Jan 7 - Jan 8, 2026
The Spanish Suite Campo de Fiori

Hotel dei Barbieri

Hotel dei Barbieri
4.0 star property
Sant'Eustachio
8.6 out of 10, Excellent, (182)
"Excellent location, accommodating and helpful staff. "
United States
Stephen
The price is P9,116
P11,065 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hotel dei Barbieri

Lh Royal Suites

Lh Royal Suites
Sant'Eustachio
9.4 out of 10, Exceptional, (70)
"The property was good. Rooms were clean."
United Kingdom
Alina
The price is P6,727
P8,229 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Lh Royal Suites

Relais Teatro Argentina

Relais Teatro Argentina
Sant'Eustachio
8.8 out of 10, Excellent, (36)
"The room was very nice and the staff was extremely helpful. "
United States
Bart
Relais Teatro Argentina

Magenta Collection Sant'Anna

Magenta Collection Sant'Anna
Sant'Eustachio
9.0 out of 10, Wonderful, (93)
"Property was convenient and walking distance from all the great sights and restaurants."
United States
Rashelle
Magenta Collection Sant'Anna

Assunta Domus

Assunta Domus
Sant'Eustachio
9.6 out of 10, Exceptional, (221)
"Very pleasant stay in a safe and easily walkable neighbourhood."
Canada
Sandy
The price is P7,740
P9,344 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Assunta Domus

The Pantheon Iconic Rome Hotel, Autograph Collection

The Pantheon Iconic Rome Hotel, Autograph Collection
5.0 star property
Sant'Eustachio
9.2 out of 10, Wonderful, (145)
"Fantastic place to stay."
Australia
Srdjan
The price is P23,513
P27,247 total
includes taxes & fees
Jan 20 - Jan 21, 2026
The Pantheon Iconic Rome Hotel, Autograph Collection

Dimora Coppelle - Adults Only

Dimora Coppelle - Adults Only
Sant'Eustachio
10.0 out of 10, Exceptional, (46)
"Nice spacious room, staff were very helpful and welcoming "
Ireland
Eoghan
The price is P9,568
P11,355 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Dimora Coppelle - Adults Only

Argentina Residenza Style Hotel

Argentina Residenza Style Hotel
4.0 star property
Sant'Eustachio
9.4 out of 10, Exceptional, (1004)
"Great location, nice staff."
United Kingdom
Conall
The price is P8,809
P10,727 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Argentina Residenza Style Hotel

Little Queen Relais

Little Queen Relais
Sant'Eustachio
8.8 out of 10, Excellent, (106)
"It was nice. Staff was great. Good location"
United States
Christina
The price is P5,794
P7,203 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Little Queen Relais

Palazzo Navona

Palazzo Navona
4.0 star property
Sant'Eustachio
9.4 out of 10, Exceptional, (1001)
"Amazing staff!!!"
Canada
Anna
Palazzo Navona

Hotel Smeraldo

Hotel Smeraldo
3.0 star property
Sant'Eustachio
9.6 out of 10, Exceptional, (1003)
"Excellent property and the excellent staff and good location "
United States
Raul
The price is P7,041
P8,575 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hotel Smeraldo

Hotel della Torre Argentina

Hotel della Torre Argentina
3.0 star property
Sant'Eustachio
9.0 out of 10, Wonderful, (260)
"Great location hotel, rooms were well equipped. Staff were friendly and helpful. Breakfast was just right for starting the day"
United Kingdom
Gareth
Hotel della Torre Argentina

Torre Argentina Relais

Torre Argentina Relais
Sant'Eustachio
9.4 out of 10, Exceptional, (538)
"Staff was very attentive. Very good breakfast and hotel was in a great location. "
United States
Michelle
Torre Argentina Relais

Relais Maddalena

Relais Maddalena
Sant'Eustachio
9.4 out of 10, Exceptional, (798)
"The room was very nice and cozy The location is good The staff is nice "
United States
sandra
The price is P11,886
P13,904 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Relais Maddalena

Juno Pantheon

Juno Pantheon
Sant'Eustachio
7.4 out of 10, Good, (10)
"Habitación excelente y todo muy bien la recomiendo un 10"
Spain
Alfonso
Juno Pantheon

Hotel Barrett

Hotel Barrett
3.0 star property
Sant'Eustachio
9.0 out of 10, Wonderful, (445)
"lovely hotel with a keen eye for detail"
United Kingdom
JACKI
The price is P8,600
P10,290 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hotel Barrett
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sant'Eustachio

Find the best Sant'Eustachio areas and neighborhoods for the activities you enjoy most.

Rome City Centre

Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Rome City Centre. Top attractions like Trevi Fountain and Piazza Navona are major draws. Catch the metro at Venezia Tram Stop or Arenula-Cairoli Tram Station to see more of the city.

Rome Historic Centre

Visit the center of Italy’s capital and enjoy traditional Italian food. Relax in old bars and see some of the city’s famous historic sites.

Trastevere

Consider a visit to Basilica of Santa Maria in Trastevere and take some time to enjoy the colorful gardens during your time in Trastevere. If you want to see more of the city, jump on the metro at Trastevere/Min. P. Istruzione Tram Stop or Induno Tram Stop.

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

Trevi

Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

Top Sant'Eustachio Hotel Reviews

Frequently asked questions

What's it like in Sant'Eustachio?
Guests are sure to enjoy their time checking out all that Rome's Sant'Eustachio neighborhood has to offer. Are you looking for Sant'Eustachio travel tips? Be sure to check out Palazzo Madama and San Luigi dei Francesi while you're in the neighborhood.
What's the best accommodation in Sant'Eustachio?
Based on Expedia customer reviews, Domna Luxury Suites is the highest ranked property in Sant'Eustachio. This guesthouse is steps from Pantheon, and offers free WiFi and concierge services. Other favorite options in the area include Hotel L'Orologio Roma and Hotel Smeraldo.
How many hotels should I expect to find in Sant'Eustachio?
Expedia has 173 hotels and other accommodations in Sant'Eustachio to choose from, making this an ideal home base for exploring the greater Rome area.
If I need to cancel my hotel reservation in Sant'Eustachio, will I receive a refund?
Yes, the majority of room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and get a refund within 24 hours of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in Sant'Eustachio.
What is there to do in this Rome neighborhood?
Palazzo Madama, San Luigi dei Francesi, and Teatro Argentina are notable landmarks to see while you're in Sant'Eustachio. You could also plan a visit to Corso Vittorio Emanuele II or Sant'Ivo alla Sapienza while you're in the neighborhood. Favorite places to visit in the surrounding area include Piazza Navona, Trevi Fountain, and Colosseum. While you're out sightseeing, Campo de' Fiori and Piazza di Spagna are a couple of additional sights to visit in Rome.

Explore a world of travel with Expedia