Sanctuary Hotels near Sanibel

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sanctuary hotels

The Nile

The Nile
2.0 star property
23.8 km from Sanctuary
The price is P15,155
P25,991 total
includes taxes & fees
May 23 - May 24
The Nile

Sanibel Inn

Sanibel Inn
3.0 star property
East End, 13.8 km from Sanctuary
9.2 out of 10, Wonderful, (1,005 reviews)
"We enjoyed our stay with a relaxing day on the beach. Everyone was friendly & helpful and our room was very comfortable."
United States
Mary
The price is P22,997
P29,481 total
includes taxes & fees
Jun 7 - Jun 8
Sanibel Inn

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
20.4 km from Sanctuary
9.4 out of 10, Exceptional, (1,347 reviews)
"Staff very friendly, room clean and property very clean "
United States
Kenneth
The price is P17,950
P24,002 total
includes taxes & fees
Jun 3 - Jun 4
Pink Shell Beach Resort and Marina

Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
22 km from Sanctuary
8.6 out of 10, Excellent, (1,006 reviews)
"Place is quiet and right down the street from the beach"
United States
Bryan
The price is P6,645
P7,410 total
includes taxes & fees
May 10 - May 11
Latitude 26 Waterfront Resort & Marina

DiamondHead Beach Resort

DiamondHead Beach Resort
3.5 star property
22.3 km from Sanctuary
9.2 out of 10, Wonderful, (1,166 reviews)
"Great room, great staff and great beach! Really enjoyed the location as well. Would stay here again"
United States
Kristen
The price is P12,036
P15,778 total
includes taxes & fees
May 12 - May 13
DiamondHead Beach Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 13.1 km from Sanctuary
9.2 out of 10, Wonderful, (1,873 reviews)
"Loved the room and the location, the grounds were beautiful and had a convenient beach access, very charming!"
United States
Hillary
The price is P15,701
P19,022 total
includes taxes & fees
May 31 - Jun 1
Sanibel Island Beach Resort

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
19.3 km from Sanctuary
8.8 out of 10, Excellent, (1,001 reviews)
"Wonderful location and accommodations!"
United States
Karen
The price is P6,222
P6,938 total
includes taxes & fees
May 20 - May 21
Residence Inn by Marriott Fort Myers Sanibel

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
21.8 km from Sanctuary
9.0 out of 10, Wonderful, (1,463 reviews)
"Loved the resort and amenities"
United States
Steven
The price is P9,766
P12,241 total
includes taxes & fees
May 12 - May 13
Lani Kai Beachfront Resort

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
23.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,446 reviews)
"Love it here! Clean rooms, great staff, great breakfast!"
United States
Amy
The price is P6,668
P7,435 total
includes taxes & fees
May 25 - May 26
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
15.6 km from Sanctuary
8.6 out of 10, Excellent, (1,011 reviews)
"Our favorite place to stay!"
United States
Tammy
The price is P15,701
P19,628 total
includes taxes & fees
Jun 1 - Jun 2
Marriott Sanibel Harbour Resort & Spa

Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.0 star property
3.7 km from Sanctuary
8.6 out of 10, Excellent, (1,003 reviews)
"View from room was amazing. "
United States
Timothy
The price is P16,450
P20,456 total
includes taxes & fees
May 13 - May 14
Tween Waters Island Resort & Spa

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
19.9 km from Sanctuary
8.2 out of 10, Very Good, (1,145 reviews)
"Clean room, nice pool, near beaches, good breakfast."
United States
Kenneth
The price is P4,801
P5,353 total
includes taxes & fees
Jun 7 - Jun 8
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Allure Suites

Allure Suites
3.0 star property
27.2 km from Sanctuary
7.6 out of 10, Good, (1,005 reviews)
"Everything was great and wonderful next time i go to cape coral we will stay there "
United States
Alejandro
The price is P4,724
P5,267 total
includes taxes & fees
May 10 - May 11
Allure Suites

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
30.1 km from Sanctuary
8.6 out of 10, Excellent, (866 reviews)
"Best Fairfield we have stayed in."
United States
Martin
The price is P5,383
P6,002 total
includes taxes & fees
May 27 - May 28
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers
3.0 star property
30.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,009 reviews)
"Great breakfast, nice room, will stop in again. "
United States
GARY
The price is P7,558
P8,427 total
includes taxes & fees
May 10 - May 11
Homewood Suites by Hilton - Fort Myers

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island, 12.8 km from Sanctuary
8.6 out of 10, Excellent, (2,644 reviews)
"Great place! Very clean, great amenities."
United States
Karen
The price is P22,896
P28,830 total
includes taxes & fees
May 12 - May 13
Sundial Beach Resort & Spa

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
29.5 km from Sanctuary
8.8 out of 10, Excellent, (1,010 reviews)
"Nice room, comfortable stay and good breakfast."
United States
Tia
The price is P6,718
P7,490 total
includes taxes & fees
Jun 7 - Jun 8
Hilton Garden Inn Ft Myers

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
30.8 km from Sanctuary
8.8 out of 10, Excellent, (1,101 reviews)
"Great place to stay "
United States
Gabriela
The price is P6,441
P7,182 total
includes taxes & fees
Jun 7 - Jun 8
Doubletree by Hilton Fort Myers at Bell Tower Shops

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
23.1 km from Sanctuary
9.2 out of 10, Wonderful, (1,009 reviews)
"The room was clean and comfortable"
United States
Robert Harold
The price is P5,618
P6,265 total
includes taxes & fees
May 21 - May 22
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
22.9 km from Sanctuary
8.6 out of 10, Excellent, (1,006 reviews)
"Breakfast was good and parking excellent "
United States
Catherine
The price is P5,400
P6,021 total
includes taxes & fees
May 25 - May 26
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanctuary

Find the best Sanctuary areas and neighborhoods for the activities you enjoy most.

Mid Island

While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.

West End

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing.

Shell Harbor

Though Shell Harbor might not have many top sights, you can venture to the surrounding area to see attractions like Sanibel Moorings Botanical Gardens and Sanibel Sea School.

Top Sanctuary Hotel Reviews

Frequently asked questions

What is Sanctuary like?
Travelers are sure to enjoy a stay in Sanibel's Sanctuary neighborhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.
How many hotels are there in the Sanctuary area?
With 10 Expedia hotels and other accommodations in Sanctuary to choose from, this is a good starting point for exploring the greater Sanibel area.
If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review top deals in Sanctuary.
What is there to do around this Sanibel neighborhood?
J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.

Explore a world of travel with Expedia