Top 10 Hotels Near San Sebastiano in Milan for 2026

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Our top choices for San Sebastiano hotels

A modern hotel room with a large bathtub, a bed, a seating area, and a view of the city at night.

A modern living room with leather sofas, a coffee table, and a TV displaying 'AF DUOMO'.

A modern bathroom with a marble backsplash, a glass shower enclosure, and a wooden bench.

A modern hotel room with a wooden parquet floor, a large bathtub, a dining area with a glass table and chairs, and a living area with sofas and a TV.

1. AF Duomo - Milano Luxury Suites

Centro Storico, 0.3 km from San Sebastiano

"Location is perfect if you don’t mind being in a tourist area but it’s not congested. It’s near great restaurants, entertainment and attractions. The staff is amazing especially the wonderful ladies that clean and handle the amazing breakfast. I stayed in Loft 10 it was a little warm but overall I would stay there again. Front desk Kevin was super helpful day and night. Thank you AFduomo"

edwin

P33,604

P38,958 total

includes taxes & fees

Oct 27 - Oct 28

A historic building with a prominent entrance, arched windows, and a balcony with balustrades.

A buffet with various fruits, vegetables, and prepared dishes.

A modern outdoor living area with a sofa, chairs, and a table, surrounded by potted plants and a glass door leading to a balcony.

A modern lobby with green and red seating, a patterned carpet, and artwork on the walls.

2. Room Mate Collection Giulia, Milan

Centro Storico, 0.4 km from San Sebastiano

John

P29,730

P34,126 total

includes taxes & fees

Oct 25 - Oct 26

A narrow cobblestone street lined with multi-story buildings, featuring balconies and large windows.

A modern hotel room with a large bed, a desk, and a patterned wall.

A modern living room with a sofa, a dining table with chairs, a kitchen area with a red appliance, and a flat-screen TV mounted on a wooden panel.

A room with a window overlooking a cityscape, featuring a building with a green dome and a bell tower.

3. Oriana Homèl Milano

Centro Storico, 0.1 km from San Sebastiano

Katrina

P16,601

P19,613 total

includes taxes & fees

Oct 4 - Oct 5

A yellow building with a balcony, arched windows, and a door with a sign.

A dining area with tables set for a meal, a variety of desserts displayed, and a view of the outdoors through a window.

A lobby with a central column, a round ceiling light, a green plant, and a black leather sofa.

A balcony with a white cat, a stone balustrade, and green plants.

4. Hotel Gran Duca di York True Stay

Centro Storico, 0.2 km from San Sebastiano

kristine

P18,115

P20,922 total

includes taxes & fees

Oct 18 - Oct 19

A modern living room with a grey sofa, a dining table, and a TV mounted on the wall.

A modern living room with a sofa, a dining table with chairs, and a TV mounted on the wall.

A modern kitchen with a microwave, toaster, and a bowl on the counter.

A modern hallway with a wooden panel wall, a metal sculpture, and a chair.

5. Heart Milan Apartments - Duomo District

Centro Storico, 0.1 km from San Sebastiano

Ghassan

P17,057

P20,115 total

includes taxes & fees

Oct 20 - Oct 21

A building with a sign reading 'CASA LAVENI' and a visible entrance with columns.

An outdoor seating area with two white cushioned chairs, a small round table with a lamp, and a potted plant.

A modern interior with a reception desk, seating area, and a large potted plant.

A modern interior with dark blue walls, bookshelves, and round tables with stools.

6. Casa Laveni

Brera, 0.6 km from San Sebastiano

Alexis

P28,725

P32,593 total

includes taxes & fees

Oct 12 - Oct 13

The entrance to Hotel Spadari with a glass door, potted plants, and a signboard.

A buffet table with various pastries and a tiered dessert display in a hotel lobby.

A modern hotel room with a wooden desk, two grey chairs, and a large window with a view of city buildings.

A hotel room with a bed, a desk, a chair, and a view of the outside.

7. Hotel Spadari al Duomo True Stay

Centro Storico, 0.2 km from San Sebastiano

Joseph

P26,551

P30,629 total

includes taxes & fees

Oct 26 - Oct 27

A rooftop restaurant with outdoor seating overlooking a cityscape.

A tall building with a colorful facade, multiple windows, and a ground-level entrance with a shop named "The Square".

A buffet with various fruits, pastries, and desserts.

A modern hotel lobby with a reception desk, seating area, and large windows offering city views.

8. The Square Milano Duomo - Preferred Hotels & Resorts

Centro Storico, 0.3 km from San Sebastiano

Melissa

P22,736

P26,433 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a large bed, a desk, a chair, a television, and a chandelier.

A modern hotel room with a dining area, a flat-screen TV, a small table with a vase of flowers, and a bar area with stools.

A modern living room with a flat-screen TV, a white entertainment unit, a round coffee table, and a kitchen area with a dining table and bar stools.

A modern hotel room with a large bed, a chandelier, and a balcony with a city view.

9. Luxury Suite Milano Duomo

Centro Storico, 0.4 km from San Sebastiano

Ashwani

P14,541

P17,347 total

includes taxes & fees

Oct 18 - Oct 19

A bedroom with a bed, bedside table, and a mirror.

A hotel room with a bed, a wardrobe, a dining table with chairs, and a window with curtains.

A modern bedroom with a bed, a seating area, and a wardrobe.

A modern interior with a long corridor, wooden panel walls, a seating area with a table, and large windows offering views of greenery.

10. Casa Brivio

Centro Storico, 0.4 km from San Sebastiano

Chandi

P20,961

P24,409 total

includes taxes & fees

Oct 27 - Oct 28

A modern kitchen with dark cabinets, a white countertop, and a built-in oven.

A modern room with a white table, two white mugs with Italianway logos, a magazine on the table, and a black couch in the background.

A modern hotel room with a large bed, a painting on the wall, a window, and a radiator.

A modern room with a dark sofa, a white round table, and a wall-mounted artwork.

11. Italianway Comfort - Torino 48

Centro Storico, 0.1 km from San Sebastiano

Farah

P10,222

P18,930 total

includes taxes & fees

Sep 28 - Sep 29

A spacious indoor dining area with multiple seating arrangements, including booths and tables, and is adorned with large chandeliers and potted plants.

A modern indoor pool area with a waterfall feature, lounge seating, and contemporary decor.

A historic building with ornate architecture, large windows, and a prominent dome.

A modern hotel lobby with a reception desk, potted plants, a pool area, and a chandelier.

12. Palazzo Cordusio Gran Meliá – The Leading Hotels of the World

Centro Storico, 0.4 km from San Sebastiano

Laurel

P72,460

P81,414 total

includes taxes & fees

Oct 17 - Oct 18

A table with two drinks and snacks, surrounded by chairs and a green hedge in the background.

A modern hotel lobby with marble flooring, seating areas, a bar, and large windows offering a view of greenery.

A hotel reception area with a marble reception desk, a large window, and a view of the outside.

A buffet area with various food items, including cakes, pastries, and a granola bar dispenser.

13. Hotel Milano Castello

Brera, 0.6 km from San Sebastiano

Junghee

P23,290

P26,615 total

includes taxes & fees

Oct 2 - Oct 3

A balcony with a wooden table, two glasses of orange juice, and a plate of croissants.

A modern apartment with a staircase, a kitchen, and a living area with a sofa and cushions.

A modern living room with a white sofa, a dining table with chairs, a bookshelf, and a flat-screen TV mounted on the wall.

A modern kitchen with a dining area, wooden flooring, and a large wall clock.

14. Heart Milan Apartments Duomo Missori

Centro Storico, 0.2 km from San Sebastiano

P16,763

P19,791 total

includes taxes & fees

Oct 20 - Oct 21

A spacious lobby with high ceilings, large columns, and a central seating area.

A spacious lobby with large windows, a central chandelier, and a view of the cityscape.

A spacious living room with a sofa, armchair, and ottoman, large windows with curtains, and a view of the cityscape.

An outdoor dining area with tables set for two, surrounded by lush greenery and architectural elements.

15. Palazzo Touring Club Milan, A Radisson Collection Hotel

Centro Storico, 0.4 km from San Sebastiano

Jing

P31,118

P35,938 total

includes taxes & fees

Oct 26 - Oct 27

A modern restaurant with glass tables and chairs, large windows, and indoor plants.

A hotel entrance with a glass door, outdoor seating area with planters, and a sign indicating the hotel's name.

An outdoor seating area with a sofa, chairs, and a laptop on a table.

A modern interior with a glass desk, a white chair, and a large window.

16. The Street Milano Duomo | a Design Boutique Hotel

Centro Storico, 0.6 km from San Sebastiano

Erma Leticia

P28,077

P32,309 total

includes taxes & fees

Oct 11 - Oct 12

A hallway with a modern design, featuring a sign that reads "THE ROOMS BOUTIQUE HOTEL MILANO".

A modern hotel room with a large bed, bedside lamps, a built-in desk, and a minibar.

A modern reception area with a marble reception desk, a white chair, and a glass partition.

A modern lobby with marble flooring and walls, a staircase, and two elevators.

17. TheROOMS by TheFLOOR Collection

0.3 km from San Sebastiano

Isal

P13,258

P15,936 total

includes taxes & fees

Oct 11 - Oct 12

A restaurant with a view of a historic building, outdoor seating with tables and chairs, and a modern interior with a sofa and cushions.

A modern living room with a sofa set, a glass coffee table, and a bookshelf.

A modern bathroom with a freestanding bathtub, a large mirror, and a vanity with a marble countertop.

A breakfast setup with pastries, coffee, and a vase of flowers in front of a large window with a grid pattern.

18. Park Hyatt Milano

Centro Storico, 0.4 km from San Sebastiano

Miguel

P102,832

P114,823 total

includes taxes & fees

Oct 10 - Oct 11

A rooftop terrace with outdoor seating and a city skyline view.

A modern interior with yellow chairs and tables, a red wall, and a geometric ceiling design.

A hotel reception area with a modern design, including a reception desk, a mounted television, and a coffee machine.

19. B&B Hotel Milano City Center Duomo

Brera, 0.6 km from San Sebastiano

Naveed

P13,021

P15,675 total

includes taxes & fees

Oct 18 - Oct 19

A restaurant with checkered flooring, tables set with white tablecloths, and shelves with glassware.

A modern living room with a sofa, armchairs, a coffee table, and a dining area with a table and chairs.

A hotel room with a bed, a sofa, a chair, a small table, and a balcony with a view of buildings.

A hotel room with a bed, a nightstand, a lamp, a window with curtains, and a view of the outside.

20. Speronari Suites

Centro Storico, 0.2 km from San Sebastiano

Christine

P26,025

P29,980 total

includes taxes & fees

Oct 18 - Oct 19

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Top San Sebastiano Hotel Reviews

Rosa Grand Milano - Starhotels Collezione

10/10 Excellent

"Loved our stay at the Rosa Grand which was centrally located to everything we wanted to do. Shout out to Maria who checked us in. She was awesome!!"

Hotel Dei Cavalieri Milano Duomo

10/10 Excellent

"Great hotel great staff! Excellent location rooftop bars is everything!!"

Hotel Brunelleschi

8/10 Good

"Breakfast was fabulous… great variety."

ibis Milano Centro

8/10 Good

"Everything’s was okay"

Hotel Cavour

8/10 Good

"The air conditioning was not controllable from the room so it was freezing in the room. Had to waste electricity by opening the wi do’s to warm the room. Otherwise, everything else was great."

Hotel Berna

8/10 Good

"From outside hotel appearance isn't that inviting, but inside the hotel has a warm inviting appearance. Biggest plus was the welcome from the staff and the general helpfulness. Room was a bit dated, but was comfortable. Location excellent for onward train station connections."

B&B HOTEL Milano Duomo Velasca

10/10 Excellent

"Clean and just a moments walk to the domo"

The Square Milano Duomo - Preferred Hotels & Resorts

10/10 Excellent

"Large clean room with great amenities."

UNA Hotels Cusani Milano

8/10 Good

"The location of the hotel is great. We were able to walk everywhere. The staff was very helpful and friendly. Breakfast buffet was good as there was plenty of choices and everything was fresh. I would definitely recommend having an Apertivo at the bar. We parked our rental car in the hotel garage and that worked great as it was in a secure location. My only complaint was the room that they assigned us was very dark. There was only one window and a huge wall. If you get assigned Room 116, I would ask for a different room .When I booked the room, the photos showed lots of natural light and two large windows but I think we got unlucky getting this room because of its location. Otherwise, the room was great, clean and spacious."

Other attractions near San Sebastiano

Biblioteca Ambrosiana

10.0/10 (1 review)

One of Europe’s first public libraries is home to Leonardo da Vinci’s Codex Atlanticus, which is housed alongside a huge book and art collection.

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Via Torino

During your visit to Milan, you can search for that perfect souvenir at Via Torino. Make time to visit the area's stunning cathedral, or simply enjoy its charming cafes.

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Chiesa di San Sepolcro

Chiesa di San Sepolcro is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Discover the area's acclaimed art scene and stunning cathedral.

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Chiesa di Sant'Alessandro in Zebedia

Chiesa di Sant'Alessandro in Zebedia is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Add the area's shops or stunning cathedral to your travel plans.

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Chiesa Santa Maria Presso di San Satiro

9.0/10 (12 reviews)

Chiesa Santa Maria Presso di San Satiro is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Add the area's stunning cathedral or shops to your travel plans.

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Museo Mangini Bonomi

You can study the exhibits at Museo Mangini Bonomi, a museum with a storied past, during your trip to Milan. Experience the area's fascinating museums and acclaimed art scene.

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Trezzo Live Club

You can get tickets for a performance at Trezzo Live Club during your stay in Milan. Make time to visit the area's stunning cathedral, or simply enjoy its charming cafes.

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Casa Ferrario

You can study the exhibits at Casa Ferrario, a museum with a storied past, during your trip to Milan. Discover the area's acclaimed art scene and stunning cathedral.

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Frequently asked questions

What's the area like around San Sebastiano?

San Sebastiano is located in a historic area of Milan known for its stunning cathedral and top museums. If you're looking for a convenient place to stay, check out the 1337 hotels and other accommodations you'll find within a mile.

What's the best place to stay near San Sebastiano?

Adjacent to San Sebastiano, Hotel Dei Cavalieri Milano Duomo is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a bar. Other good options within a short distance include Hotel Cavour and The Square Milano Duomo - Preferred Hotels & Resorts.

How many hotels are there close to San Sebastiano?

Expedia has 1337 hotels and other accommodations within a mile from San Sebastiano.

If I need to cancel the hotel reservation for my stay near San Sebastiano, will I receive a refund?

Yes, you'll find most room reservations are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best options available near San Sebastiano.

What can I see and do near San Sebastiano?

Castello Sforzesco, Pinacoteca di Brera, and Leonardo da Vinci Museum of Science and Technology feature captivating exhibits. Sights like Cathedral of Milan, Milan Baptistery, and Galleria Vittorio Emanuele II are must-sees while exploring the area. You can check out the local talent at Teatro Dal Verme, Teatro alla Scala, and Teatro San Babila.

How can I get to San Sebastiano?

With so many choices for transportation, seeing all of the area near San Sebastiano is simple. You can access metro transit at Duomo Station, Via Orefici P.za Cordusio Tram Stop, and Cordusio M1 Tram Stop. If you're taking a train into town, Milan Cadorna Nord Station and Milan (XNC-Cadorna Train Station) are the closest stations to Milan Centre.

Hotels near San Sebastiano

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for San Sebastiano hotels

1. AF Duomo - Milano Luxury Suites

2. Room Mate Collection Giulia, Milan

3. Oriana Homèl Milano

4. Hotel Gran Duca di York True Stay

5. Heart Milan Apartments - Duomo District

6. Casa Laveni

7. Hotel Spadari al Duomo True Stay

8. The Square Milano Duomo - Preferred Hotels & Resorts

9. Luxury Suite Milano Duomo

10. Casa Brivio

11. Italianway Comfort - Torino 48

12. Palazzo Cordusio Gran Meliá – The Leading Hotels of the World

13. Hotel Milano Castello

14. Heart Milan Apartments Duomo Missori

15. Palazzo Touring Club Milan, A Radisson Collection Hotel

16. The Street Milano Duomo | a Design Boutique Hotel

17. TheROOMS by TheFLOOR Collection

18. Park Hyatt Milano

19. B&B Hotel Milano City Center Duomo

20. Speronari Suites

Top San Sebastiano Hotel Reviews

Rosa Grand Milano - Starhotels Collezione

Hotel Dei Cavalieri Milano Duomo

Hotel Brunelleschi

ibis Milano Centro

Hotel Cavour

Hotel Berna

B&B HOTEL Milano Duomo Velasca

The Square Milano Duomo - Preferred Hotels & Resorts

UNA Hotels Cusani Milano

Other attractions near San Sebastiano

Biblioteca Ambrosiana

Via Torino

Chiesa di San Sepolcro

Chiesa di Sant'Alessandro in Zebedia

Chiesa Santa Maria Presso di San Satiro

Museo Mangini Bonomi

Trezzo Live Club

Casa Ferrario

Frequently asked questions