San Francisco Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 17 - Nov 18
Tomorrow
Nov 18 - Nov 19
This weekend
Nov 21 - Nov 23
Next weekend
Nov 28 - Nov 30

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending San Francisco hotels

Outdoor pool, free cabanas, pool umbrellas
Hotel Gran David

Hotel Gran David

3.5 star property
Santiago
8.4 out of 10, Very Good, (346)
"Great service "
United States
Herb
Hotel Gran David
2 outdoor pools, open 7:00 AM to 5:00 PM, pool umbrellas, sun loungers
Hotel Galería

Hotel Galería

3.0 star property
Nuevo Santiago
8.4 out of 10, Very Good, (199)
"SC"
Mexico
AXEL
The price is P3,779
P4,157 total
includes taxes & fees
Nov 18 - Nov 19
Hotel Galería
Terrace/patio
Hotel Mykonos Panama

Hotel Mykonos Panama

3.5 star property
Nuevo Santiago
8.8 out of 10, Excellent, (533)
"Great place to stay for a stop over , conveniently located off the highway and close to shopping areas"
United States
Andy
The price is P5,020
P5,522 total
includes taxes & fees
Nov 18 - Nov 19
Hotel Mykonos Panama
Outdoor pool
HOTEL VISTA LAGO

HOTEL VISTA LAGO

3.0 star property
La Pena
9.2 out of 10, Wonderful, (74)
"perfect for an overnight stop on the road, beautiful view of the lake and good restaurant"
Canada
Géraldine
The price is P4,518
P4,969 total
includes taxes & fees
Nov 18 - Nov 19
HOTEL VISTA LAGO
Restaurant
Hotel Anachoreo

Hotel Anachoreo

3.0 star property
Santa Fe
9.4 out of 10, Exceptional, (35)
"Excellent accommodation: Room, grounds, and common area are beautifully decorated and spotless clean. Staff were friendly & helpful. Only problem was issue with hot water heater the day of our stay. "
United States
James
Hotel Anachoreo
Terrace/patio
La Qhia Eco Retreat

La Qhia Eco Retreat

2.5 star property
Santa Fe
8.0 out of 10, Very Good, (18)
"Very pretty setting. Staff was was super friendly. Restaurant/bar area was very nice. Room could very much use hooks to hang clothes as there was plenty of wall space and shelves for clothes/etc. There was little space for belongings so we had to keep our things in our bags. All else was lovely! For those that are noise sensitive, it IS Central America and dogs, roosters, cats etc….all have opinions in the weee hours of the night. I always pack ear plugs to make sure I sleep well. I highly...
United States
John
La Qhia Eco Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top San Francisco Hotel Reviews

Hotel Mykonos Panama

Hotel Mykonos Panama

10/10 Excellent
"Great room, great food and great price"
Anthony 1-night trip
Posted 3 weeks ago
Hotel Mykonos Panama

More cheap stays in San Francisco

La Qhia Eco Retreat

La Qhia Eco Retreat

Barriada el Cerro A 100 Mts De, Santa Fe, Veraguas
Get rates
7.8/10 Good! (18 reviews)

Frequently asked questions

What's the best place for a stay in San Francisco?
Hotel Gran David, located 9.5 mi (15.4 km) from the heart of San Francisco, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Hotel Mykonos Panama and HOTEL VISTA LAGO. See all available top hotels, or vacation rentals in San Francisco.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in San Francisco.
What is staying in San Francisco like?
Visitors to San Francisco are sure to find plenty to explore and enjoy. There are 17 hotels and other accommodations in the surrounding area. Find out more about San Francisco.
What should I see while I'm in San Francisco?
Places to visit in the wider area include Laguna de La Yeguada, Parque Acuatico Italia Guadalupe Panama, and Catedral of Santiago Apostol. You'll also find Los Pozos Termales and Omar Torrijos Herrera Stadium in the area. Check out what more to see and do in Expedia's San Francisco guide.
What's the weather like in San Francisco?
The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and December with an average of 77°F. The rainiest months in San Francisco are October, August, June, and November, with each month seeing an average of 18 inches of rainfall.

Explore a world of travel with Expedia