Hotels with Spa in San Diego, California

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Check availability on San Diego Hotels with Spa

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Dec 31 - Jan 1
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Jan 1 - Jan 2
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Jan 2 - Jan 4
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Jan 9 - Jan 11

Our top choices for San Diego hotels with a spa

Exterior
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1589)
"Totally Recommend! Rooms are really clean and comfortable, the staff are great as well. "
United States
Fernando
The price is P7,886
P12,178 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Hyatt Regency Mission Bay Spa and Marina
Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
National City
9.2 out of 10, Wonderful, (3592)
"Room was clean, staff was friendly and helpful."
United States
Maria
The price is P6,303
P6,946 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Best Western Plus Marina Gateway Hotel
Body treatments, aromatherapy, body wraps, body scrubs, facials
Hilton San Diego Bayfront

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1892)
"Enjoyed my stay"
United States
Brandon
The price is P7,029
P11,035 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton San Diego Bayfront
Hot stone massages, prenatal massages, sports massages, body scrubs
San Diego Mission Bay Resort

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1317)
"Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!"
United States
Haley
The price is P8,074
P12,392 total
includes taxes & fees
Jan 4 - Jan 5, 2026
San Diego Mission Bay Resort
Couples treatment rooms, body treatments, hot stone massages
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2949)
"Great boutique hotel!!"
United States
Maksim
Legacy Resort Hotel & Spa
Dinner served
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2056)
"Very comfortable, nice location and good service "
United States
ALEXANDER
The price is P11,451
P15,936 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Omni San Diego Hotel at the Ballpark
Premium bedding, in-room safe, desk, blackout drapes
Handlery Hotel

Handlery Hotel

Handlery Hotel
3.5 star property
Mission Valley
8.2 out of 10, Very Good, (2262)
"Room and staff were excellent"
United States
Bryant
Handlery Hotel
Outdoor pool
Humphreys Half Moon Inn

Humphreys Half Moon Inn

Humphreys Half Moon Inn
3.5 star property
Point Loma
9.2 out of 10, Wonderful, (2728)
"Great stay, highly recommend."
United States
Ryan
The price is P8,765
P11,251 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Humphreys Half Moon Inn
Facials, 2 treatment rooms, massages
The Westin San Diego Bayview

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1093)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is P9,480
P12,698 total
includes taxes & fees
Jan 18 - Jan 19, 2026
The Westin San Diego Bayview
Property grounds
Paradise Point Resort & Spa

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.6 out of 10, Excellent, (2366)
"Great facility and amenities. We look forward to taking our family back again. "
United States
Andy
The price is P7,612
P11,864 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Paradise Point Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Diego Hotel Reviews

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

10/10 Excellent
"Amenities were fantastic, nice staff, room carpet could be a lot cleaner "
Daisy 1-night trip
Posted 2 days ago
DoubleTree by Hilton Hotel San Diego - Mission Valley

Frequently asked questions

Looking to vacation at a spa hotel in San Diego?
Treat yourself to some pampering and book a hotel with a spa. Travelers love the historical sites and fascinating museums in San Diego so get ready for a cultural tour. Enjoy the theaters and sea views during your vacation. Spa hotels are a great way to break away from your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in San Diego?
Legacy Resort Hotel & Spa is a top spa hotel featuring a fitness center, a bar, an outdoor pool, and a restaurant. Spend an afternoon at the spa where you'll find facials, body scrubs, and Swedish massages. Other popular spa hotels in San Diego include Handlery Hotel and Hilton San Diego Bayfront.
How many spa hotels are there in San Diego?
Among Expedia's 6039 accommodation options in San Diego, there are 14 spa hotels.
What's there to see and do in San Diego?
Take in some sights and attractions while you're in San Diego by visiting San Diego Zoo, Petco Park, and Port of San Diego. If you have extra time while you're in the area, you might want to stop by Mission Bay and Mission Beach.
What is a San Diego spa hotel?
Spa hotels in San Diego have full on-site spas and offer services like therapies and a selection of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your vacation.

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