San Antonio Hotels near Cali

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Dec 27 - Dec 28
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Dec 28 - Dec 29
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Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11

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Our top choices for San Antonio hotels

Courtyard
Magic Garden House

Magic Garden House

Magic Garden House
3.0 star property
San Antonio
10.0 out of 10, Exceptional, (35)
"Very nice accommodation, great service and good location"
Germany
Klemens
Magic Garden House
Outdoor pool
Alko Hotel Casa Nispero

Alko Hotel Casa Nispero

Alko Hotel Casa Nispero
4.0 star property
San Antonio
9.4 out of 10, Exceptional, (200)
"Rooms are spacious and beautifully designed."
United States
Mark
The price is P5,942
P5,942 total
Jan 13 - Jan 14, 2026
Alko Hotel Casa Nispero
Free WiFi, bed sheets
Hotel Casa Bresse

Hotel Casa Bresse

Hotel Casa Bresse
2.5 star property
San Antonio
10.0 out of 10, Exceptional, (3)
"I am frequent in this hotel , pure colonial beauty with an inside court. Clean , spacious rooms, hot water . Staff friendly and helpful , hotel is close to everything Cali has to offer. Love it."
Canada
Stanislaw
The price is P1,903
P1,903 total
Jan 2 - Jan 3, 2026
Hotel Casa Bresse
Rooftop terrace
San Antonio Hotel Boutique

San Antonio Hotel Boutique

San Antonio Hotel Boutique
3.0 star property
San Antonio
9.2 out of 10, Wonderful, (64)
"The staff was great. "
United States
Victor
The price is P3,243
P4,194 total
Jan 7 - Jan 8, 2026
San Antonio Hotel Boutique
Front of property
Casa Ruta Sur

Casa Ruta Sur

Casa Ruta Sur
3.0 star property
San Antonio
9.8 out of 10, Exceptional, (30)
"Loved the neighborhood that this property was in. It was so pretty with lots and lots of great restaurants nearby and pretty safe. The property itself was also beautiful "
United States
Toni
The price is P3,775
P3,775 total
Jan 15 - Jan 16, 2026
Casa Ruta Sur
Free WiFi
La posada del ceramista

La posada del ceramista

La posada del ceramista
3.0 star property
San Antonio
The price is P2,220
P2,220 total
Dec 31 - Jan 1, 2026
La posada del ceramista
Hypo-allergenic bedding, desk, free WiFi, bed sheets
Santiago DC Hotel

Santiago DC Hotel

Santiago DC Hotel
3.0 star property
San Antonio
8.0 out of 10, Very Good, (2)
"The staff is very courteous. The breakfast is simple but delicious . The room was clean, spacious and with excellent AC. The only thing to consider is that there is a very cannabis friendly bar downstairs in the lobby area and you walk through it to get to your room. The rooms do not smell of cannabis but you walk through a lot of it. "
United States
Eva
The price is P2,655
P8,529 total
Jan 1 - Jan 2, 2026
Santiago DC Hotel
Terrace/patio
Epifania Guest House

Epifania Guest House

Epifania Guest House
1.0 star property
San Antonio
The price is P1,116
P1,116 total
Jan 5 - Jan 6, 2026
Epifania Guest House
Exterior
casa hostal ave maria san antonio cali

casa hostal ave maria san antonio cali

casa hostal ave maria san antonio cali
2.0 star property
San Antonio
The price is P1,175
P1,410 total
Dec 30 - Dec 31
casa hostal ave maria san antonio cali
2 outdoor pools
Hotel Real Elim International

Hotel Real Elim International

Hotel Real Elim International
4.5 star property
18.9 km from San Antonio
9.0 out of 10, Wonderful, (302)
"Excellent location very close to the airport; modern and clean beautiful hotel. "
United States
Carlos
Hotel Real Elim International
Restaurant
Mirago Hotel

Mirago Hotel

Mirago Hotel
2.5 star property
6 km from San Antonio
10.0 out of 10, Exceptional, (1)
"Excelente todo!"
Colombia
Michael
The price is P3,045
P3,045 total
Jan 5 - Jan 6, 2026
Mirago Hotel
Terrace/patio
Hotel Marrakech Cali

Hotel Marrakech Cali

Hotel Marrakech Cali
3.0 star property
5.6 km from San Antonio
The price is P2,929
P2,929 total
Jan 2 - Jan 3, 2026
Hotel Marrakech Cali
Front of property
HOTEL HYM SAS

HOTEL HYM SAS

HOTEL HYM SAS
2.5 star property
27.6 km from San Antonio
8.8 out of 10, Excellent, (3)
"Staff was friendly. The towels and linens were a bit dingy and the check in counter had a musty smell and a little disorganized. "
United States
Lucy
The price is P4,362
P4,362 total
Dec 28 - Dec 29
HOTEL HYM SAS
Premium bedding, desk, soundproofing, iron/ironing board
Hotel Thama Palmira

Hotel Thama Palmira

Hotel Thama Palmira
3.0 star property
28 km from San Antonio
8.2 out of 10, Very Good, (91)
"Everything was fine "
United States
Gary
The price is P2,962
P2,962 total
Dec 28 - Dec 29
Hotel Thama Palmira
Outdoor pool
Hotel Spirito by Spiwak

Hotel Spirito by Spiwak

Hotel Spirito by Spiwak
3.5 star property
3.3 km from San Antonio
8.4 out of 10, Very Good, (748)
"Everything was very good!! "
United States
carlos Manuel Ramos
The price is P4,533
P4,533 total
Jan 2 - Jan 3, 2026
Hotel Spirito by Spiwak
Exterior detail
Hotel Spiwak Chipichape Cali

Hotel Spiwak Chipichape Cali

Hotel Spiwak Chipichape Cali
4.5 star property
Chipichape, 3.3 km from San Antonio
8.6 out of 10, Excellent, (1003)
"Great hotel, great location, great service"
United States
Mario
Hotel Spiwak Chipichape Cali
Exterior
CasaPance Boutique Hotel

CasaPance Boutique Hotel

CasaPance Boutique Hotel
3.0 star property
11.7 km from San Antonio
The price is P4,494
P4,494 total
Jan 8 - Jan 9, 2026
CasaPance Boutique Hotel
Outdoor pool
NH Cali Royal

NH Cali Royal

NH Cali Royal
4.0 star property
8.5 km from San Antonio
8.4 out of 10, Very Good, (1002)
"Great place, great location!"
United States
Reynaldo Enrique
The price is P3,496
P3,496 total
Jan 5 - Jan 6, 2026
NH Cali Royal
Fountain
Hotel Boutique Villa Casuarinas

Hotel Boutique Villa Casuarinas

Hotel Boutique Villa Casuarinas
3.5 star property
Ciudad Jardín, 9.4 km from San Antonio
9.8 out of 10, Exceptional, (38)
"It's a dream property in the best neighborhood of Cali. The staff are incredible friendly and helpful with all that you need. An incredible pool, a tennis court, a waterfall, all in the middle of nature with amazing trees. You can order to the pool from a Peruvian restaurant that serves amazing food. They also have spa. "
United States
Jorge
The price is P4,219
P4,219 total
Jan 2 - Jan 3, 2026
Hotel Boutique Villa Casuarinas
View from room
Osve Hotel Boutique

Osve Hotel Boutique

Osve Hotel Boutique
4.0 star property
1.3 km from San Antonio
10.0 out of 10, Exceptional, (2)
"Everything was good. The room, breakfast, the swimming pool..."
Belgium
Katia
The price is P5,583
P5,583 total
Jan 2 - Jan 3, 2026
Osve Hotel Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most.

Ciudad Jardín

Unique features of Ciudad Jardín include the restaurants and shopping. Make a stop by Palmas Mall or Las Velas Shopping Center while you're exploring the area.

Granada

Visitors to Granada enjoy its shopping, and if you want to do some exploring, Lugar a Dudas is worth a stop.

El Peñon

When in El Peñon, you can plan a visit to Rock Park and El Gato Del Rio, some noteworthy sights in the nearby area.

Rozo

Check out nearby sights like Fenix Air Museum while you're spending some time in Rozo and the surrounding area.

Top San Antonio Hotel Reviews

Hotel Casa Bresse

Hotel Casa Bresse

10/10 Excellent
"I am frequent in this hotel , pure colonial beauty with an inside court. Clean , spacious rooms, hot water . Staff friendly and helpful , hotel is close to everything Cali has to offer. Love it."
Stanislaw 1-night trip
Posted 9 days ago
Hotel Casa Bresse

Frequently asked questions

What's it like in San Antonio?
Travelers to the San Antonio neighborhood in Cali will be sure to enjoy their stay.
What's a favorite place to stay in San Antonio?
Based on our traveler data, Alko Hotel Casa Nispero is one of the top choices for your stay in San Antonio. This hotel offers free breakfast and a restaurant. Other good options for your stay in the area include Hotel Casa Bresse and San Antonio Hotel Boutique.
How many hotels should I expect to find in the San Antonio area?
If you're searching for places to stay in Cali, Expedia has something to meet your needs with 43 San Antonio hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes, most room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available in San Antonio.
What can I see and do in this Cali neighborhood?
Religious Art Museum, Enrique Buenaventura Municipal Theater, and La Merced Archaeological Museum are just a few of the places to visit in and around San Antonio. While you're out sightseeing, Calima Gold Museum of the Bank of the Republic and Comfandi and Comfenalco Cultural Center are a couple of additional sights to visit in Cali.