Hotel Isa in central Rome offers a stylish escape with a rooftop terrace and garden. Enjoy the on-site café, in-room WiFi, and recommendations from multilingual staff. Visitors love the quality bar, breakfast options, and helpful service.
Reviews
9.49.4 out of 10
Exceptional
Popular amenities
Pet friendly
Free WiFi
Air conditioning
Business services
Bar
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Located in Rome City Centre, a neighborhood in Rome, Hotel Isa is near a metro station. Castel Sant'Angelo and Vatican Museums are cultural highlights, and some of the area's notable landmarks include Palace of Justice and Piazza del Popolo. Via Cola di Rienzo and Tiber River are two other places to visit that come recommended. Visit our Rome travel guide
Via Cicerone 39, Rome, RM, 186
What's nearby
Via Cola di Rienzo
2 min walk - 0.2 km
Castel Sant'Angelo
7 min walk - 0.6 km
Piazza del Popolo
10 min walk - 0.9 km
Piazza di Spagna
16 min walk - 1.4 km
Pantheon
18 min walk - 1.5 km
Getting around
Lepanto Station
10 min walk
Rome Piazzale Flaminio Station
14 min walk
Fiumicino - Leonardo da Vinci Intl. Airport (FCO)
41 min drive
Restaurants
Enoteca Costantini
2 min walk
Lumìere bistrot
1 min walk
La Fraschetta Romanesca
2 min walk
Malaterra
1 min walk
Morrison's
1 min walk
About this property
Hotel Isa
Upscale boutique hotel near Via Cola di Rienzo
Located close to Palace of Justice and Castel Sant'Angelo, Hotel Isa provides a rooftop terrace, a coffee shop/cafe, and a garden. Stay connected with free in-room WiFi, with speed of 50+ Mbps, and guests can find other amenities such as dry cleaning/laundry services and a fireplace in the lobby.
Additional perks include:
A roundtrip airport shuttle (surcharge), a 24-hour front desk, and concierge services
A banquet hall, a vegetable garden, and multilingual staff
1 meeting room, luggage storage, and tour/ticket assistance
Guest reviews say great things about the bar, breakfast, and helpful staff
Room features
All 54 individually furnished rooms feature thoughtful touches such as air conditioning, in addition to amenities like free WiFi and safes. Guest reviews say good things about the clean rooms at the property.
If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
Check-in start time: 3:00 PM; Check-in end time: 12:30 AM
Late check-in subject to availability
Minimum check-in age: 18
Check-out
Check-out before 11:00 AM
Special check-in instructions
This property offers transfers from the airport (surcharges may apply); guests must contact the property with arrival details before travel, using the contact information on the booking confirmation
Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools
Access methods
Staffed front desk
Pets
Pets allowed for an extra charge of EUR 15 per pet (varies based on length of stay)
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
1 total pets
Specific rooms only; pet-friendly rooms can be requested by contacting the property at the number on the booking confirmation
Food and water bowls are available
Children and extra beds
Children are welcome
1 child, up to the age of 2 years, can stay for free if using existing beds when occupying the parent or guardian's room
Rollaway/extra beds are not available
Cribs (infant beds) are available for EUR 20.0 per night
Property payment types
Important information
Fees
You'll be asked to pay the following charges at the property. Fees may include applicable taxes:
A tax is imposed by the city: EUR 7.50 per person, per night, up to 10 nights. This tax does not apply to children under 10 years of age.
We have included all charges provided to us by the property.
Optional extras
Airport shuttle fee: EUR 60 per vehicle
Nearby parking fee: EUR 30 per day (7 ft away)
Pet fee: EUR 15 per pet (varies based on length of stay)
Service animals are exempt from fees
Crib (infant bed) fee: EUR 20.0 per night
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property uses a grey water recycling system
Safety features at this property include a fire extinguisher
We should mention
All guests, including children, must be present at check-in and show their government-issued photo ID card or passport
Cash transactions at this property cannot exceed EUR 5000, due to national regulations; for further details, please contact the property using information in the booking confirmation
Only registered guests are allowed in the guestrooms
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)
National rating
This property has received its official star rating from the local rating authority.
Property is also known as
Design Hotel Isa
Hotel Isa
Hotel Isa Design
Isa Design
Isa Design Hotel
Isa Design Hotel Rome
Isa Design Rome
Isa Hotel
Hotel Isa Rome
Isa Rome
Hotel Isa Rome
Hotel Isa Hotel
Hotel Isa Hotel Rome
Frequently asked questions
Is Hotel Isa pet-friendly?
Yes, this property allows cats and dogs (limit 1 total). There's a fee of EUR 15 per pet, per day. Service animals are exempt from fees.
What time is check-in at Hotel Isa?
Check-in start time: 3:00 PM; Check-in end time: 12:30 AM. Late check-in is available during limited hours.
What time is check-out at Hotel Isa?
Check-out is at 11:00 AM.
Does Hotel Isa provide a shuttle to the airport?
Yes, there's an airport shuttle. A fee of EUR 60 per vehicle applies.
Where is Hotel Isa located?
This family-friendly Rome hotel is located in the historical district, within a 10-minute walk of Via Cola di Rienzo, Palace of Justice, and Castel Sant'Angelo. Tiber River and Piazza del Popolo are also within 15 minutes. Lepanto Station is 10 minutes by foot and Flaminio - Piazza del Popolo Station is 11 minutes.
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
Hotel Isa Reviews
9.4
Exceptional
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
9.6
Cleanliness
9.2
Location
9.6
Staff & service
9.2
Property conditions & facilities
Rating 10 - Excellent. 758 out of 1005 reviews
10 - Excellent
758
Rating 8 - Good. 194 out of 1005 reviews
8 - Good
194
Rating 6 - Okay. 37 out of 1005 reviews
6 - Okay
37
Rating 4 - Poor. 10 out of 1005 reviews
4 - Poor
10
Rating 2 - Terrible. 6 out of 1005 reviews
2 - Terrible
6
Reviews
8/10 Good
Nicholas
Jan 30, 2026
Liked: Cleanliness, amenities
Great location near the Vatican, the breakfast was excellent, the staff was friendly, and the old style elevator was cool.
We loved our 3-night stay at Hotel Isa. The location made everything convenient. The staff was helpful and friendly and breakfast was always wonderful.
Karen
Stayed 3 nights in Jan 2026
10/10 Excellent
John
Jan 6, 2026
Great stay at Hotel Isa over New Years. The location was convenient, staff was
Just a wonderful place to stay, great views, clean rooms and wonderful staff. Breakfast was always a treat and the location is great for walking everywhere.
Room was bright, clean, and lovely - as was the entire hotel. Convenient area, lots of great food options nearby. Staff was polite and very helpful. They realized I was there for my birthday and brought me champagne and chocolates!
Wonderful staff. Fantastic rooftop with BIG breakfast varieties and evening cocktails (full bar). In my opinion, the best location. 10 minute walk from the bustling city center but in the quieter and more easily accessible Prati neighborhood for getting in and out if you need a taxi. Taxi stand is 1 block away. Solid rooms and bathrooms. 10/10 best of all worlds when traveling to Rome for more than 3 days.
Hotel Isa is a wonderful hotel with spacious rooms in the Prati section of Rome- near the Vatican Amir Block or so off the Tiber - within walking distance of many major sites close to Metro and had a great staff breakfast was great the only issues you should be aware of is at the elevator goes up to the fifth floor and the rooftop restaurant for breakfast and bar is on the sixth where you have to walk up one flight to get to but outside of that it’s a great hotel
We had a great night at Isa hotel and the stunning view from the terrace both at night and morning at breakfast towards Peter’s cathedral was amazing!
Oeyvind
Stayed 1 night in Sep 2025
6/10 Okay
Tammy
Jan 28, 2026
Disliked: Cleanliness, amenities
The hotel is in a very convenient location, close to many major landmarks. The staff was friendly and helpful.
However, the hotel was not as clean as expected, and there was a noticeable odor in the carpet. Another disappointment was that there was no complimentary coffee — you have to pay for it.
Overall, it was an average stay with a great location and nice staff, but some basic amenities and cleanliness could be improved.
Very convenient location. Walking distance to St. Peter’s basilica and Castel Sant'Angelo. The staffs are very nice. As the platinum member of Expedia I was able to get a room upgrade.
The breakfast is really nice with a lot of selections. The avocado salad is my favorite :)
There are a lot of great restaurants in the area.
Great interior design. Breakfast buffet was included and amazing food. Rooftop bar provided a good view of the city. Staff was super friendly and helpful.