Santa Clara
Panama City
Visit Santa Clara
Things to do
Panama Canal: The Most Complete Wildlife Experience
P3,768
per adult
98% of travellers recommend
From Panama City: San Blas Island Hopping Day Tour
P9,084
per adult
98% of travellers recommend
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
P6,217
per adult
94% of travellers recommend
Half day of Panama city and canal tour: shared and private
P4,177
per adult
96% of travellers recommend
Panama City: Zip Line Experience Over The City
P2,512
per adult
94% of travellers recommend
Top hotels in Santa Clara
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
The price is P7,652 per night from Nov 22 to Nov 23
P7,652
P8,417 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (6,144 reviews)
"You staff was on top of everything thing that we needed . Very helpful in directing us to the right people and tours. They even recognize my birthday. They sent up birthday cake and a fruit basket. I was very impressed. Thanks to your lovely staff ."
Reviewed on Oct 27, 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Via Espana 111 Panama City Panama
The price is P7,279 per night from Nov 23 to Nov 24
P7,279
P8,007 total
Nov 23 - Nov 24
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
Megapolis Hotel Panamá
Avenida Balboa Panama City
The price is P10,254 per night from Oct 31 to Nov 1
P10,254
P11,279 total
Oct 31 - Nov 1
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.6/10 Excellent! (1,829 reviews)
"Very nice, clean, would recommend to anyone"
Reviewed on Oct 25, 2026
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
The price is P8,632 per night from Nov 3 to Nov 4
P8,632
P9,918 total
Nov 3 - Nov 4
includes taxes & fees
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.6/10 Excellent! (2,791 reviews)
"👍"
Reviewed on Oct 27, 2026
Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz Veracruz Panama
The price is P17,984 per night from Oct 29 to Oct 30
P17,984
P17,984 total
Oct 29 - Oct 30
includes taxes & fees
Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall ...
7.8/10 Good! (1,115 reviews)
"Great beautiful place , and the food is excellent"
Reviewed on Oct 26, 2026
Ramada Plaza by Wyndham Panama Punta Pacifica
Via Israel y Calle 71, San Francisco Panama City Panama
Fully refundableReserve now, pay when you stay
The price is P6,002 per night from Nov 11 to Nov 12
P6,002
P6,602 total
Nov 11 - Nov 12
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,409 reviews)
"Really good and clean amazing breakfast buffet"
Reviewed on Oct 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santa Clara
Find the best Santa Clara areas and neighborhoods for the activities you enjoy most.
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by Fabiola Tile
Open Photo by Fabiola Tile
Bella Vista
Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.
El Cangrejo
The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Francisco
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.
San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.
