San Francisco
Panama City
Visit San Francisco
Stay near popular San Francisco attractions
Things to do
Panama Canal: The Most Complete Wildlife Experience
P3,768
per adult
98% of travellers recommend
From Panama City: San Blas Island Hopping Day Tour
P9,084
per adult
98% of travellers recommend
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
P6,217
per adult
94% of travellers recommend
Half day of Panama city and canal tour: shared and private
P4,177
per adult
96% of travellers recommend
Panama City: Zip Line Experience Over The City
P2,512
per adult
94% of travellers recommend
Top hotels in San Francisco
Megapolis Hotel Panamá
Avenida Balboa Panama City
The price is P8,555 per night from Nov 17 to Nov 18
P8,555
P9,411 total
Nov 17 - Nov 18
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.6/10 Excellent! (1,832 reviews)
"The bed sheets were soiled in the room. Fixtures in the shower, lamps and toilet were falling a part. The staff was friendly and the breakfast was amazing. It's situated in an ideal location to get around with Uber and taxi services. The restaurant inside the hotel was nice and food came out in a ..."
Reviewed on Nov 2, 2026
Ramada Plaza by Wyndham Panama Punta Pacifica
Via Israel y Calle 71, San Francisco Panama City Panama
The price is P6,501 per night from Nov 9 to Nov 10
P6,501
P7,152 total
Nov 9 - Nov 10
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
Decapolis Hotel Panama City
Avenida Balboa Con Multicentro Panama City Panama
The price is P6,003 per night from Nov 29 to Nov 30
P6,003
P6,603 total
Nov 29 - Nov 30
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,731 reviews)
"We always stay there and have a good experience, good breakfast and very nice staff"
Reviewed on Nov 2, 2026
Aloft by Marriott Panama
Via Israel & Calle 76 Panama City Panama
The price is P8,318 per night from Nov 10 to Nov 11
P8,318
P9,150 total
Nov 10 - Nov 11
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and a nightclub. Our guests praise the helpful staff in our reviews. ...
Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
The price is P9,558 per night from Nov 8 to Nov 9
P9,558
P10,514 total
Nov 8 - Nov 9
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in ...
Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is P8,358 per night from Nov 21 to Nov 22
P8,358
P9,194 total
Nov 21 - Nov 22
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in San Francisco
Find the best San Francisco areas and neighborhoods for the activities you enjoy most.
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by Fabiola Tile
Open Photo by Fabiola Tile
Bella Vista
Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.
El Cangrejo
The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.
Calidonia
You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Lotería Station or Santo Tomás Station to see more of the city.
