O Brien Hotels

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Our top choices for O Brien hotels

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
8.2 out of 10, Very Good, (107 reviews)
"Dog friendly and price."
United States
John
The price is P3,488
P3,924 total
includes taxes & fees
Mar 1 - Mar 2
Motel 6 – Lake City, Fl – Medical Center

Econo Lodge Live Oak

Econo Lodge Live Oak
2.0 star property
Live Oak
7.0 out of 10, Good, (282 reviews)
"Clean room with plenty of towels and soaps. "
United States
Melissa
The price is P4,455
P4,901 total
includes taxes & fees
Mar 22 - Mar 23
Econo Lodge Live Oak

Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
2.5 star property
Live Oak
7.0 out of 10, Good, (526 reviews)
"Clean spacious rooms, friendly staff, convenient location "
United States
Jerry
The price is P6,128
P6,740 total
includes taxes & fees
Mar 22 - Mar 23
Quality Inn & Suites Live Oak I-10 Exit 283

Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very Good, (798 reviews)
"The room was clean. Bed was comfortable. Staff very nice. Breakfast was delicious. Great experience "
United States
Frank
The price is P5,971
P6,569 total
includes taxes & fees
Mar 15 - Mar 16
Holiday Inn Express & Suites Live Oak by IHG

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (639 reviews)
"Hotel is an older facility but room was clean and staff were exceptionally friendly and professional."
United States
Wayne
The price is P4,131
P4,544 total
includes taxes & fees
Mar 8 - Mar 9
Quality Inn White Springs Suwanee

High Springs Country Inn

High Springs Country Inn
2.0 star property
High Springs
8.4 out of 10, Very Good, (21 reviews)
"The room was spotless. Clean hot showers. Very well priced. Nice staff"
United States
Richard
The price is P4,531
P5,097 total
includes taxes & fees
Mar 17 - Mar 18
High Springs Country Inn

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (408 reviews)
"Beautiful room, very clean and the bed was incredibly soft and comfortable to sleep in! "
United States
Julians
The price is P4,655
P5,237 total
includes taxes & fees
Feb 23 - Feb 24
BlueGem Motel

Royal Inn

Royal Inn
2.0 star property
Alachua
7.2 out of 10, Good, (192 reviews)
"Good value and close to highway. "
United States
Ross
The price is P10,381
P11,679 total
includes taxes & fees
Feb 28 - Mar 1
Royal Inn

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (176 reviews)
"We had such a great time, the cabin was nice and clean and had everything you might need. We loved the little detail of the handwritten postcard and map! The fireplace area was so nice too, perfect for a little getaway! "
United States
Ellie
The price is P5,728
P11,393 total
includes taxes & fees
Feb 23 - Feb 24
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (485 reviews)
"We visited family in the area and stayed here, hotel was clean, quiet, staff was great and room was so comfortable and spacious for our family of 5. Will definitely stay again!"
United States
Libbi
The price is P7,082
P7,967 total
includes taxes & fees
Feb 26 - Feb 27
Hampton Inn & Suites Alachua I-75

Americas Best Value Inn Alachua

Americas Best Value Inn Alachua
2.0 star property
Alachua
4.8 out of 10, (606 reviews)
"Nicer than a Marriott. "
United States
Dan
The price is P4,869
P5,478 total
includes taxes & fees
Mar 1 - Mar 2
Americas Best Value Inn Alachua

Cindys Motel

Cindys Motel
2.5 star property
Mayo
8.8 out of 10, Excellent, (129 reviews)
"Easy parking next to your door and easy check in.beds are comfy and as a single parent traveler i felt safe"
United States
Diane
Cindys Motel

Suwannee River Rendezvous

Suwannee River Rendezvous
2.5 star property
Mayo
8.8 out of 10, Excellent, (24 reviews)
"Awesome place to stay, beautiful location and great accommodations. Friendly staff and lots to do!"
United States
Lauren
Suwannee River Rendezvous

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,001 reviews)
"Staff and hotel were wonderful!"
United States
Sandra
The price is P5,902
P6,640 total
includes taxes & fees
Mar 15 - Mar 16
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.6 out of 10, Exceptional, (1,001 reviews)
"The staff is great"
United States
Tana
The price is P6,222
P7,000 total
includes taxes & fees
Mar 1 - Mar 2
Comfort Suites Lake City

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,000 reviews)
"The room was very clean and comfortable. Excellent breakfast and staff was very friendly and helpful."
United States
Kenneth
The price is P7,175
P8,072 total
includes taxes & fees
Feb 22 - Feb 23
Hampton Inn & Suites Lake City

Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,002 reviews)
"Great place"
United States
John
The price is P5,034
P5,663 total
includes taxes & fees
Feb 22 - Feb 23
Holiday Inn & Suites Lake City by IHG

Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (764 reviews)
"This is an excellent hotel while you roadtrip:)"
United States
Desiree Moreno
The price is P7,666
P8,624 total
includes taxes & fees
Feb 22 - Feb 23
Home2 Suites by Hilton Lake City

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
3.0 star property
Lake City
9.0 out of 10, Wonderful, (198 reviews)
"Great hotel "
United States
Guillermo
The price is P6,191
P6,965 total
includes taxes & fees
Mar 1 - Mar 2
Fairfield Inn & Suites Lake City

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
2.5 star property
Lake City
8.8 out of 10, Excellent, (1,080 reviews)
"Excellent place to stay."
United States
Donovan
The price is P6,249
P7,030 total
includes taxes & fees
Mar 15 - Mar 16
La Quinta Inn & Suite by Wyndham Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

More cheap stays in O Brien

Frequently asked questions

Where is the best place to stay in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, located 29.9 mi (48.2 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are La Quinta Inn & Suite by Wyndham Lake City and Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy. See all available top hotels, or vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
What are some accommodations with pools in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG: Offers buffet, an outdoor pool, and complimentary wired internet access. La Quinta Inn & Suite by Wyndham Lake City and Tru by Hilton Lake City are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.
How is it to stay in O Brien?
Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodations to choose from. Find out more about O Brien.
What should I see while I'm in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Bob's River Place in the area. Check out what more to see and do in Expedia's O Brien guide.
What's the seasonal weather like in O Brien?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.

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