Photo by Ryan de los Reyes

Family friendly Hotels in Northeast Missouri, Missouri

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 6 - Nov 7
Tomorrow
Nov 7 - Nov 8
This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Our top choices for Northeast Missouri family-friendly hotels

A bedroom with a four-poster bed, a bedside table with a lamp, a desk with a telephone, and a bathroom with a bathtub and a hanging plant.

1. Depot Inn and Suites

Depot Inn and Suites
3.5 star property
La Plata
9.8 out of 10, Exceptional, (746 reviews)
  • cleanliness
    Let the kids loose at this La Plata hotel with indoor pools, playground, and game room for endless family fun.
The price is P5,759
P6,240 total
includes taxes & fees
Dec 6 - Dec 7
Depot Inn and Suites
A modern dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and a patterned wall decoration.

2. Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG
2.5 star property
Kirksville
9.2 out of 10, Wonderful, (582 reviews)
  • cleanliness
    Family-friendly fun begins with an indoor pool adventure just a short drive from Thousand Hills State Park for outdoor exploration.
The price is P6,489
P7,354 total
includes taxes & fees
Dec 6 - Dec 7
Holiday Inn Express & Suites Kirksville - University Area by IHG
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

3. Best Western On The River

Best Western On The River
2.5 star property
Hannibal
8.8 out of 10, Excellent, (1,003 reviews)
  • cleanliness
    Family-friendly riverside hotel offers kids' paradise with indoor and outdoor pools, hot tub, and nearby fun park adventures.
The price is P6,417
P7,401 total
includes taxes & fees
Nov 8 - Nov 9
Best Western On The River
A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

4. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
Hannibal
9.6 out of 10, Exceptional, (1,000 reviews)
  • cleanliness
    Splash into a family vacation haven at this Sleep Inn & Suites with indoor pool, fitness center, and kid-friendly amenities.
The price is P6,908
P8,038 total
includes taxes & fees
Dec 6 - Dec 7
Sleep Inn & Suites Hannibal West
A hotel with a swimming pool, outdoor seating, and a sign for 'Pinemark Inn Suites & Events'.

5. Pinemark Inn & Suites

Pinemark Inn & Suites
2.0 star property
St. Clair
9.6 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Family-friendly destination with seasonal pool and firepits makes for perfect relaxation in St. Clair.
The price is P8,542
P9,351 total
includes taxes & fees
Nov 9 - Nov 10
Pinemark Inn & Suites
A Comfort Inn hotel with a modern design, featuring a covered entrance and a clear sky in the background.

6. Comfort Inn Sullivan

Comfort Inn Sullivan
2.5 star property
Sullivan
8.6 out of 10, Excellent, (959 reviews)
  • cleanliness
    Dive into family adventures at Meramec State Park with indoor pool thrills just minutes from nature trails.
The price is P7,176
P7,820 total
includes taxes & fees
Nov 26 - Nov 27
Comfort Inn Sullivan
A hotel room with two beds, a nightstand with a lamp, and a window with blinds.

7. Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area
2.5 star property
Kirksville
8.8 out of 10, Excellent, (292 reviews)
The price is P4,095
P4,600 total
includes taxes & fees
Dec 6 - Dec 7
Super 8 by Wyndham Kirksville-University Area
A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

8. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
Hannibal
8.0 out of 10, Very good, (1,002 reviews)
  • cleanliness
    Family escape with an indoor pool and spacious rooms where kids splash while parents relax at the poolside bar and sun loungers.
The price is P4,718
P5,489 total
includes taxes & fees
Nov 29 - Nov 30
Quality Inn & Suites Hannibal West
A spacious living room with a large painting, a fireplace, a staircase, and modern furniture.

9. Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.2 out of 10, Wonderful, (741 reviews)
  • cleanliness
    Splash into family adventures with an indoor pool, hot tub, and cozy accommodations just steps from exciting zipline thrills.
The price is P8,442
P9,612 total
includes taxes & fees
Dec 1 - Dec 2
Best Western Plus Washington Hotel
A hotel room with a large bed, two bedside lamps, a nightstand with a phone, a mirror, and a bathtub.

10. Oak Hill Inn & Suites

Oak Hill Inn & Suites
2.5 star property
Canton
9.2 out of 10, Wonderful, (1,005 reviews)
The price is P5,919
P6,746 total
includes taxes & fees
Dec 5 - Dec 6
Oak Hill Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at family-friendly hotels in Northeast Missouri

Breakfast included
Pool