Murex Lakes Hotels near Sanibel

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Dec 21 - Dec 22
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Dec 22 - Dec 23
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Dec 26 - Dec 28
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Our top choices for Murex Lakes hotels

3 restaurants, breakfast, lunch, dinner served; Italian cuisine
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
14.9 km from Murex Lakes
9.0 out of 10, Wonderful, (1023)
"Clean rooms, friendly staff, so much to do there and nearby "
United States
Lisa R
The price is P9,924
P12,375 total
includes taxes & fees
Dec 23 - Dec 24
Lani Kai Beachfront Resort
Exterior
Woodspring Suites Fort Myers - Cape Coral

Woodspring Suites Fort Myers - Cape Coral

Woodspring Suites Fort Myers - Cape Coral
2.5 star property
29.1 km from Murex Lakes
7.2 out of 10, Good, (147)
"For the price, the sheets were clean. "
United States
Dairon
The price is P4,345
P4,845 total
includes taxes & fees
Dec 22 - Dec 23
Woodspring Suites Fort Myers - Cape Coral
Sundeck
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
15.6 km from Murex Lakes
8.8 out of 10, Excellent, (1004)
"Great Place to Stay!"
United States
JUDY
The price is P6,606
P7,366 total
includes taxes & fees
Dec 22 - Dec 23
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Exterior
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
17.6 km from Murex Lakes
9.4 out of 10, Exceptional, (1000)
"Great rooms, good staff"
United States
Dedan
The price is P7,223
P8,053 total
includes taxes & fees
Dec 24 - Dec 25
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Free daily buffet breakfast
Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
14.2 km from Murex Lakes
8.6 out of 10, Excellent, (1002)
"The property was clean and the breakfast was excellent the staff was friendly and convenient to Sanibel Island"
United States
robert
The price is P7,927
P8,839 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Residence Inn by Marriott Fort Myers Sanibel
On the beach, sun loungers, beach towels
Sanibel Island Beach Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 5.3 km from Murex Lakes
9.2 out of 10, Wonderful, (1479)
"Great place."
United States
Michael
The price is P15,209
P18,426 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Sanibel Island Beach Resort
Lobby lounge
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
25.7 km from Murex Lakes
8.6 out of 10, Excellent, (788)
"Clean room and very nice staff "
United States
Michael
The price is P5,049
P5,629 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
Terrace/patio
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
25.7 km from Murex Lakes
8.8 out of 10, Excellent, (1001)
"Great amenities, pool and spa, clean room, beautiful lobby and good on site restaurant "
United States
Aleksandar
The price is P6,287
P7,010 total
includes taxes & fees
Dec 28 - Dec 29
Hilton Garden Inn Ft Myers
Water view
Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs
3.0 star property
29.2 km from Murex Lakes
8.8 out of 10, Excellent, (706)
"Super location charming place, a total hidden gem!"
United States
Jay
Latitude 26 Waterfront Boutique Resort - Bonita Springs
Premium bedding, down comforters, desk, laptop workspace
Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral
2.0 star property
28.7 km from Murex Lakes
7.6 out of 10, Good, (199)
"Microwave made an explosion when tried to use it. The rest amazing"
United States
Alain
The price is P4,175
P5,398 total
includes taxes & fees
Dec 29 - Dec 30
Quality Inn Fort Myers Cape Coral
2 outdoor pools
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
14.7 km from Murex Lakes
8.6 out of 10, Excellent, (1575)
"Great resort fun bar beautiful pool walkable area variety of restaurants and clean beach"
United States
Erika
The Lighthouse Resort Inn & Suites
Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe
The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
15.7 km from Murex Lakes
9.0 out of 10, Wonderful, (1004)
"Excellent stay over Thanksgiving holiday!"
United States
Nicole
The price is P9,670
P13,131 total
includes taxes & fees
Dec 22 - Dec 23
The Westin Cape Coral Resort At Marina Village
Outdoor pool, cabanas (surcharge), sun loungers
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
14.7 km from Murex Lakes
9.0 out of 10, Wonderful, (1716)
"Great place "
United States
Debra Sue
The price is P10,517
P14,673 total
includes taxes & fees
Dec 22 - Dec 23
Margaritaville Beach Resort Fort Myers
Terrace/patio
Dolphin Key Resort

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
21 km from Murex Lakes
8.8 out of 10, Excellent, (1208)
"Nice room, helpful staff, nice heated pool, bar/restaurant on site has good prices and live entertainment most nights. Overall, a fun place to stay."
United States
Jacob
The price is P5,872
P6,548 total
includes taxes & fees
Dec 29 - Dec 30
Dolphin Key Resort
Property entrance
Matlacha Tiny Village

Matlacha Tiny Village

Matlacha Tiny Village
3.0 star property
22 km from Murex Lakes
8.8 out of 10, Excellent, (268)
"Very nice place with all necesary accommodations for a Pleasant stay. "
United States
isabel
The price is P7,346
P12,596 total
includes taxes & fees
Dec 22 - Dec 23
Matlacha Tiny Village
Living area
TriLuxe Inn & Studios

TriLuxe Inn & Studios

TriLuxe Inn & Studios
2.0 star property
17.4 km from Murex Lakes
8.2 out of 10, Very Good, (17)
"Everything was great, will definitely be coming back"
United States
Ruben
The price is P5,931
P8,512 total
includes taxes & fees
Jan 2 - Jan 3, 2026
TriLuxe Inn & Studios
Bar (on property)
Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
26.6 km from Murex Lakes
8.8 out of 10, Excellent, (1006)
"Very nice hotel"
United States
Ashley
The price is P7,415
P8,268 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Doubletree by Hilton Fort Myers at Bell Tower Shops
Reception
Americas Best Value Inn Ft. Myers

Americas Best Value Inn Ft. Myers

Americas Best Value Inn Ft. Myers
3.0 star property
27.6 km from Murex Lakes
7.6 out of 10, Good, (1124)
"Loved it. The staff was great rooms were clean. "
United States
Austin
The price is P4,024
P4,487 total
includes taxes & fees
Dec 22 - Dec 23
Americas Best Value Inn Ft. Myers
View from room
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
14.7 km from Murex Lakes
8.0 out of 10, Very Good, (1005)
"Nice staff, clean and convenient. Will stay again. "
United States
Josephine
The price is P6,765
P7,543 total
includes taxes & fees
Dec 22 - Dec 23
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
View from room
Pointe Estero Beach Resort

Pointe Estero Beach Resort

Pointe Estero Beach Resort
2.0 star property
19.6 km from Murex Lakes
9.2 out of 10, Wonderful, (1001)
"Could not beat the ocean view!!"
United States
BETH
The price is P10,218
P30,464 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Pointe Estero Beach Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Murex Lakes

Find the best Murex Lakes areas and neighborhoods for the activities you enjoy most.
Fort Myers which includes a beach
Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography
Open Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography

West End

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

Mid Island

While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing.

Sanctuary

While Sanctuary might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Blind Pass Beach and Turner Beach.

Top Murex Lakes Hotel Reviews

Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina

10/10 Excellent
"got the 2 bdr unit next to office. rooms were great, check inn easy, pool and hot tub made it very enjoyable. my only complaint was i only booked for 1 night. will be my stop when return"
David 1-night trip
Posted 3 days ago
Matanzas Inn Bayside Resort and Marina

Frequently asked questions

What's it like in Murex Lakes?
You'll be sure to have fun visiting Sanibel's Murex Lakes neighborhood.
How many hotels are there in Murex Lakes?
If you're searching for places to stay in Sanibel, choose from one of Expedia's 17 hotels and other accommodations in Murex Lakes.
If I need to cancel my hotel reservation in Murex Lakes, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view the top deals on offer in Murex Lakes.
What is there to do around this Sanibel neighborhood?
Sanibel Captiva Conservation Foundation, Bailey - Matthews Shell Museum, and Sanibel Island Southern Beach are just a few of the places to visit in and around Murex Lakes. When you're sightseeing in Sanibel, Sanibel Historical Museum and Village and Sanibel Historical Village and Museum are also worth a stop.

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