Mesopotamia

Travel Guide

Mesopotamia featuring a river or creek and forest scenes
Mesopotamia showing forest scenes
Mesopotamia
Mesopotamia which includes a river or creek and forest scenes
Mesopotamia showing a river or creek and a waterfall

The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration.

A heady mix of ancient history, natural beauty and flamboyant festivals features in Argentina’s hot and humid Mesopotamia region. Be inspired by thundering waterfalls, spot exotic wildlife, experience indigenous traditions and relax at sleepy riverside resorts. Mesopotamia sits sandwiched between two mighty rivers, the Río Paraná and Rió Uruguay, and is covered with subtropical rainforests and wetlands. It includes the provinces of Misiones, Corrientes and Entre Ríos.

Straddling the Río Iguazú in Misiones province, and shared between Argentina and Brazil, is the UNESCO-protected Iguazú National Park. Come here to admire the 275 individual waterfalls that make up the Iguazú Falls. Follow trails to panoramic lookouts, ride on a speedboat beneath a cascade and see wildlife such as toucans and monkeys. Access the Brazilian side of the park via a short drive from the town of Puerto Iguazú.

Tour the towns of Misiones to appreciate the province’s diversity. Find a gemstone mine in Wanda, flower-filled gardens in Montecarlo and colonial architecture in Oberá. Visit 17th-century Jesuit ruins at San Ignacio. Saltos del Moconá, in Parque Provincial Moconá, is another waterfall worth visiting.

Discover a breezy esplanade, graceful architecture and artisan markets, which showcase Guarani culture, in Corrientes city. Spend some time at easy-going river towns, including Itati and Ituzaingó. Be amazed by the craggy, granite ravine of Barrancas del Empedrado and hike amid thick forest in Mburucuya National Park. Go in search of some 350 bird species and the rare maned wolf at Esteros del Iberá wetlands reserve.

Hot springs, fishing trips, pristine reserves and boisterous carnival parties await in Entre Ríos province. Gualeguaychú explodes into color in February with arguably Argentina’s most famous carnival. The powdery, white sand at nearby Ñandubaysal evokes images of a tropical island paradise. Fish for huge dorado in Santa Elena and enjoy the charm of riverfront Colón. Don’t miss the enormous yatay palm trees in El Palmar National Park.

The southern area of Mesopotamia is just a short bus ride from Buenos Aires. You can also fly to Corrientes and Puerto Iguazú and then get around the region via public buses and organized tours.

Costarenas Hotel & Spa

Costarenas Hotel & Spa

3.5 out of 5
12 de Abril y Quiros, Colon, Entre Rios
The price is P6,169 per night from Oct 14 to Oct 15
P6,169
P6,169 total
Oct 14 - Oct 15
Stay at this 3.5-star spa hotel in Colon. Enjoy free breakfast, free WiFi, and an outdoor pool. Popular attractions Dr. Herminio J. Quiros Park and Termas De ...
Costarenas Hotel & Spa
Hotel y Spa Termas del Este

Hotel y Spa Termas del Este

3 out of 5
Presidente Raúl alfonsín 877, Federacion
Stay at this 3-star spa hotel in Federacion. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Termas Federacion Water Park and Termas de ...
Hotel y Spa Termas del Este
Hathor Concordia

Hathor Concordia

3 out of 5
Ruta Nacional 14-km 264.5, Concordia, Entre Rios
Stay at this 3-star business-friendly hotel in Concordia. Enjoy free breakfast, free WiFi, and room service. Popular attractions Concordia Golf Course and Castillo ...
Hathor Concordia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Agustín 1 Apart

Agustín 1 Apart

4 out of 5
130 Gral. Pedro Ferré, Parana, Entre Ríos
Stay at this 4-star aparthotel in Parana. Enjoy free WiFi, parking (surcharge), and onsite spa services. Popular attractions Plaza de Mayo and Museu De Sitio ...
9/10 Wonderful! (4 reviews)
Indico
"Meu problema foi só a garagem, o apartamento é ótimo, limpeza estava impecável."

Reviewed on Jan 25, 2025

Agustín 1 Apart
Donsuites Apart Hotel

Donsuites Apart Hotel

3 out of 5
La Rioja 442, Corrientes, Corrientes
Stay at this 3-star aparthotel in Corrientes. Enjoy free breakfast, free WiFi, and a rooftop terrace. Popular attractions Museo de Artesanías Tradicionales Folclóricas ...
8.6/10 Excellent! (103 reviews)
"Loved this place, super clean, and the staff were very nice and helpful😍"

Reviewed on Aug 30, 2024

Donsuites Apart Hotel
cabañas tesouro

cabañas tesouro

3 out of 5
mariano sanchez 158, Gualeguaychú, Entre Ríos
Stay at this 3-star cabin in Gualeguaychú. Enjoy free WiFi, a garden, and furnished balconies or patios. Popular attractions Nuestra Senora Gaucha del Mate Monument ...
"Nos tocaron vecinos bastante ruidosos, y se escuchaban sus conversaciones, porque la pared medianera es de 15. Pero la propiedad bien valio la pena, es comoda y funcional, volveriamos sin dudar."

Reviewed on May 8, 2023

cabañas tesouro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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