A river winding through a dense forest.

Mesopotamia Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Oct 25 - Oct 26
Tomorrow
Oct 26 - Oct 27
Next weekend
Oct 30 - Nov 1
In two weeks
Nov 6 - Nov 8

Filter by

Star rating

Guest rating

Our top choices for Mesopotamia hotels

1. Hathor Concordia

Hathor Concordia
Concordia
Australia
Jose
P3,855
P4,555 total
Nov 17 - Nov 18
Hathor Concordia

2. Club Valle Termal Resort

Club Valle Termal Resort
Federacion
United States
Luis
P3,967
P3,967 total
Oct 26 - Oct 27
Club Valle Termal Resort

3. Mayim Hotel Termal & SPA

Mayim Hotel Termal & SPA
Concordia
Costa Rica
Federico
P6,357
P6,357 total
Oct 27 - Oct 28
Mayim Hotel Termal & SPA

4. Maran Suites & Towers - Hotel & Spa

Maran Suites & Towers - Hotel & Spa
Parana
United States
Michael
P6,490
P6,490 total
Oct 27 - Oct 28
Maran Suites & Towers - Hotel & Spa

5. Complejo La Loma

Complejo La Loma
Federacion
Canada
Logan
P2,991
P3,074 total
Oct 26 - Oct 27
Complejo La Loma

6. HOTEL TERMAS VICTORIA Wellness Spa

HOTEL TERMAS VICTORIA Wellness Spa
Victoria
Spain
Mariela Emilia
P7,738
P7,738 total
Oct 27 - Oct 28
HOTEL TERMAS VICTORIA Wellness Spa

7. Costarenas Hotel & Spa

Costarenas Hotel & Spa
Colon
Argentina
Lisette
P7,727
P7,727 total
Oct 26 - Oct 27
Costarenas Hotel & Spa

8. La Regina Lodge

La Regina Lodge
Municipo de Itati
Brazil
Marcos
P3,672
P3,672 total
Oct 26 - Oct 27
La Regina Lodge

9. Intersur Colon

Intersur Colon
Colón
United States
Carla
P7,087
P7,087 total
Oct 26 - Oct 27
Intersur Colon

10. Turismo Hotel Casino

Turismo Hotel Casino
Corrientes
United States
Laura
P5,894
P5,894 total
Nov 15 - Nov 16
Turismo Hotel Casino

11. O2 Hotel Gualeguaychú

O2 Hotel Gualeguaychú
Gualeguaychú
United States
Allan
P2,910
P2,910 total
Oct 26 - Oct 27
O2 Hotel Gualeguaychú

12. Hotel Rio

Hotel Rio
Chajarí
Brazil
Eduardo
P5,457
P5,457 total
Oct 26 - Oct 27
Hotel Rio

13. Marriott Corrientes Hotel

Marriott Corrientes Hotel
Corrientes
Australia
Marcus
P9,677
P9,677 total
Nov 1 - Nov 2
Marriott Corrientes Hotel

14. Rio Arriba Suites Apartments y Resto

Rio Arriba Suites Apartments y Resto
Bella Vista
Brazil
Anonymous traveler
P3,897
P3,897 total
Oct 27 - Oct 28
Rio Arriba Suites Apartments y Resto

15. Donsuites Apart Hotel

Donsuites Apart Hotel
Corrientes
United States
Nora
P4,395
P4,395 total
Oct 26 - Oct 27
Donsuites Apart Hotel

16. Ayres Inn

Ayres Inn
Federal
P4,274
P4,274 total
Oct 26 - Oct 27
Ayres Inn

17. Hotel y Spa Termas del Este

Hotel y Spa Termas del Este
Federacion
Canada
Chase
P3,481
P3,481 total
Nov 1 - Nov 2
Hotel y Spa Termas del Este

18. La Alondra Casa De Huéspedes

La Alondra Casa De Huéspedes
Corrientes
United States
Ken
P6,099
P6,099 total
Nov 15 - Nov 16
La Alondra Casa De Huéspedes

19. Complejo Anjana

Complejo Anjana
Federación
United States
jeff
P3,304
P3,304 total
Oct 26 - Oct 27
Complejo Anjana

20. Rincón del Socorro

Rincón del Socorro
Mercedes
United States
Anonymous traveler
Rincón del Socorro
View all properties

Vacation Rentals in Mesopotamia

Condo

Club Valle Termal Resort

Club Valle Termal Resort
Federacion
"Hh"
Club Valle Termal Resort
Aparthotel

Complejo La Loma

Complejo La Loma
Federacion
"Had a very good experience here. Hosts do not speak English, but were very patient with me as I used Google Translate to communicate. Woman at the desk was very kind. I had arrived late and was able to check in without issue. The suite is great - there is a full bathroom, bedroom and kitchen / dining area. There is a communal pool outside in the courtyard as well with lounge chairs. Breakfast was decent as well. Parking on site. I would stay here again for sure, but would be better for multiple...
Complejo La Loma
Cabin

Bungalows Mexico

Bungalows Mexico
Concepción del Uruguay
"Todo como esperaba. Muy bien. Amables. Lugar en condiciones. "
Bungalows Mexico
Apartment

Agustín 1 Apart

Agustín 1 Apart
Parana
"Everything about the place was great. Our only complaint was that the kettle didn't heat water so it was hard to make mate. "
Agustín 1 Apart
Aparthotel

Donsuites Apart Hotel

Donsuites Apart Hotel
Corrientes
"Loved this place, super clean, and the staff were very nice and helpful😍"
Donsuites Apart Hotel
See all vacation rentals
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Mesopotamia attractions

A dirt path through a dense palm tree forest.

El Palmar National Park

8.0/10 (2 reviews)
Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.
See properties
A stone pergola with steps leading up to it, surrounded by greenery and a clear sky.

Costanera de Corrientes

9.0/10 (4 reviews)
Enjoy an outing to Costanera de Corrientes during your stay in Corrientes. You can enjoy the restaurants while in the area.
See properties
A large church with a prominent dome and two bell towers.

Basilica Nuestra Senora De Itati

Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati.
See properties

Termas de Federacion

10.0/10 (2 reviews)
Bring your family to Termas de Federacion and have a fun-filled day at this amusement park in Federacion. Stroll along the beaches or discover the area's waterfalls.
See properties

Concepción del Uruguay City Racetrack

You can take time to visit Concepción del Uruguay City Racetrack during your travels to Concepción del Uruguay. Experience the area's art scene and museums.
See properties

Termas Concepcion Entrerios

Bring your family to Termas Concepcion Entrerios and enjoy the excitement of this amusement park in Concepción del Uruguay. Experience the area's art scene and museums.
See properties

Isla Cambacua Beach

8.8/10 (5 reviews)
Why not spend a lazy afternoon at Isla Cambacua Beach during your trip to Concepción del Uruguay? Experience the area's art scene and museums.
See properties

Victoria Beach

If a restful vacation is part of your travel plans, Victoria Beach might be the perfect place to seek out during your trip to Victoria. Make some time to visit the monuments while you're in the area.
See properties

Learn more about Mesopotamia

The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration.

See all hotels in Mesopotamia
A series of waterfalls surrounded by dense green forest.

Top Mesopotamia Hotel Reviews

Holiday Inn Rosario by IHG

Holiday Inn Rosario by IHG

10/10 Excellent
"Lo que más nos gustó del hotel fué la localización, cerca de la casa de nuestros familiares, en una parte céntrica de la ciudad y en una zona cercana a restaurantes y tiendas. el servicio de wifi del hotel no tuvo ninguna falla, pudimos trabajar sin interrupciones a cualquier hora del día. Normalmente, en otros hoteles, el wifi se hace más lento en la noche, pero en este hotel simplemente era rápido a cualquier hora del día. La atención del personal sobresaliente! este hotel es sumamente recomendable especialmente para gente que tiene que viajar por trabajo"
MARIA 4-night trip
Posted 2 days ago
Holiday Inn Rosario by IHG
Marriott Corrientes Hotel

Marriott Corrientes Hotel

10/10 Excellent
"2 cosas, faltaban toallas en el baño y otra que no me atendieron para poder pedir otra reserva"
Patricia 1-night trip
Posted 6 days ago
Marriott Corrientes Hotel
Holiday Inn Express Rosario by IHG

Holiday Inn Express Rosario by IHG

10/10 Excellent
"El hotel y sus instalaciones son excelentes. Solo sugeriría mejorar el espacio para servirse el desayuno ya que es muy pequeño y cuando hay mucha gente se complica andar transitando con la bandeja y los platos y/o tazas ya servidas. Por todo lo demás no hay nada más para acotar ya que nuestra estadía fue muy buena"
Jose 1-night trip
Posted 12 days ago
Holiday Inn Express Rosario by IHG
Howard Johnson by Wyndham Rosario

Howard Johnson by Wyndham Rosario

10/10 Excellent
"Parking sin entregar llave sería lo ideal"
Mariano 1-night trip
Posted 2 weeks ago
Howard Johnson by Wyndham Rosario
Dazzler by Wyndham Rosario

Dazzler by Wyndham Rosario

10/10 Excellent
"Very good!"
Ysidora 3-night trip
Posted 2 weeks ago
Dazzler by Wyndham Rosario
Days Inn by Wyndham Zarate

Days Inn by Wyndham Zarate

10/10 Excellent
"Hotel cómodo para viajeros o familia. Parar ahí es evitar capital federal o ahorrar tiempo de viaje"
Eduardo 1-night trip
Posted 3 weeks ago
Days Inn by Wyndham Zarate
Hathor Concordia

Hathor Concordia

8/10 Good
"EVERYTHING WAS GOOD"
Jose 1-night trip
Posted 1 month ago
Hathor Concordia
hotel san lorenzo design

hotel san lorenzo design

10/10 Excellent
"Buen hotel, se duerme bien y no se escucha ruido de afuera"
Omar 1-night trip
Posted 1 month ago
hotel san lorenzo design
Mercure Hotel Rosario

Mercure Hotel Rosario

8/10 Good
"Not what we expected"
Juan 1-night trip
Posted 1 month ago
Mercure Hotel Rosario

More cheap stays in Mesopotamia

Como en casa

Como en casa

San Luis 948 8B Rosario Santa Fe
P2,162
P2,162 total
Oct 28 - Oct 29
8.4/10 Very Good! (7 reviews)
Como en casa
hotel san lorenzo design

hotel san lorenzo design

san lorenzo 1138 Corrientes Corrientes Province
P2,576
P2,576 total
Oct 26 - Oct 27
5.4/10 (6 reviews)
hotel san lorenzo design
O2 Hotel Gualeguaychú

O2 Hotel Gualeguaychú

115 3 de Febrero Gualeguaychú Entre Ríos
P2,910
P2,910 total
Oct 26 - Oct 27
O2 Hotel Gualeguaychú
ibis Puerto General San Martin

ibis Puerto General San Martin

El Espinillo Puerto General San Martín San Lorenzo
P4,865
P4,865 total
Nov 8 - Nov 9
10/10 Exceptional! (1 review)
ibis Puerto General San Martin
Carat Apart Boutique

Carat Apart Boutique

Montevideo 1552 Rosario Santa Fe
P5,280
P5,280 total
Nov 1 - Nov 2
9.6/10 Exceptional! (57 reviews)
Carat Apart Boutique
Hotel Casino Rio Uruguay

Hotel Casino Rio Uruguay

RN117 Paso de los Libres Corrientes
Get rates
10/10 Exceptional! (1 review)
Hotel Casino Rio Uruguay

Find out more about Mesopotamia

Top reasons to visit Mesopotamia

  • Stunning National Parks: Mesopotamia is renowned for its breathtaking national parks, ideal for hiking and exploring lush landscapes.
  • Outdoor Adventures: Engage in thrilling activities such as birdwatching and wildlife exploration amidst the region's natural beauty.
  • Charming Picnic Areas: Enjoy picturesque scenery and delightful picnic spots, perfect for relaxation and romance.
  • Comfortable Accommodations: A variety of hotels provide excellent services, ensuring a memorable family vacation experience.
  • Scenic City Views: Discover stunning city vistas and beautiful properties that enhance your holiday backdrop.

Find great hotels near Mesopotamia

Discover the charm of Mesopotamia, Argentina, where a variety of hotels await to enhance your family vacation experience. From comfortable accommodations to exceptional services, you’ll find the perfect place to unwind. Whether you're seeking the best hotels or looking for competitive room rates, Mesopotamia offers a delightful blend of hospitality. Explore guest reviews to ensure your stay is memorable, making your visit to this enchanting region truly special.

  • El Tránsito Hotel Boutique: A family-friendly haven, El Tránsito Hotel Boutique is nestled 29.0km from Mesopotamia, offering a delightful retreat for travellers seeking a memorable family vacation experience. The hotel boasts child-centric amenities, including free cribs, a children's pool, and an arcade game room, ensuring younger guests are entertained throughout their stay. With its charming décor and welcoming atmosphere, this 3.5-star establishment is perfect for families looking to unwind and explore the beauty of Argentina together.

Where to stay near Mesopotamia

In Mesopotamia, Argentina, travellers can immerse themselves in a captivating blend of romance and relaxation. This enchanting region offers a plethora of outdoor adventures, picturesque scenery, and charming picnic areas. Explore popular destinations that showcase stunning city views and beautiful properties, providing the perfect backdrop for an unforgettable holiday. Whether you seek tranquil nature or vibrant local culture, Mesopotamia promises a delightful escape filled with unique experiences.

  • Mercedes: Nestled approximately 49.9km from Mesopotamia, Mercedes is a vibrant city that offers a delightful blend of outdoor activities and scenic beauty. With visitor numbers peaking in July and December to January, it’s a year-round destination for those seeking adventure. The city is renowned for its golf courses and water parks, making it ideal for families and thrill-seekers alike. Nearby attractions include a national state park and a popular theme park, ensuring that there is always something exciting to explore. Whether you’re hiking through lush landscapes or enjoying a sunny day at the water park, Mercedes promises an unforgettable travel experience.
  • Concepción: Just 35.4km from Mesopotamia, Concepción is a charming city that attracts visitors with its stunning natural surroundings. This city experiences peak visitor numbers in April, July, and September, making it an excellent choice for outdoor enthusiasts. The nearby national and natural parks provide ample opportunities for hiking, bird watching, and enjoying the great outdoors. Concepción is perfect for those seeking adventure and tranquillity, with its breathtaking scenery offering a picturesque backdrop for any vacation. Embrace the beauty of nature and the spirit of adventure in this welcoming city.
  • Uguay: Located 27.4km away from Mesopotamia, Uguay is a quaint village that offers a unique travel experience for those seeking a quieter getaway. With seasonal visitor peaks in January, March, and November, Uguay’s charm lies in its serene atmosphere and proximity to beautiful natural parks. Ideal for nature lovers, this village provides a peaceful retreat where you can immerse yourself in the local flora and fauna. Enjoy leisurely walks through picturesque landscapes, and let the tranquil environment rejuvenate your spirit during your stay in Uguay.

Things to do in Mesopotamia

In Mesopotamia, Argentina, visitors can immerse themselves in the region's natural beauty through activities like birdwatching, hiking, and wildlife exploration. The area boasts lovely outdoor seating options, allowing tourists to relax and appreciate the stunning landscapes. Whether you're seeking adventure or tranquility, Mesopotamia offers a delightful blend of outdoor experiences to enrich your holiday.

Shopping

In Mesopotamia, explore the Shopping Sur, where you'll find a variety of local crafts and souvenirs. For a more traditional experience, visit the Mercado Municipal de Posadas, offering fresh produce and unique artisan goods perfect for gifts. Enjoy the vibrant atmosphere while you shop.

Recreation

Mesopotamia offers tranquil wellness retreats like the Eco-Lodge Spa, where you can indulge in rejuvenating treatments surrounded by lush forests. Engage in yoga sessions by the river or explore the nearby nature reserves, perfect for hiking and birdwatching, all while enjoying the picturesque landscapes and serene atmosphere.

Adventure

The Ibera Wetlands offer an extraordinary wildlife experience, with boat tours revealing capybaras, caimans, and diverse bird species in their natural habitat. For thrill-seekers, the stunning landscapes of Misiones National Park provide opportunities for hiking amidst waterfalls and lush rainforest, perfect for adventure and exploration.

Nightlife

Explore the vibrant nightlife at La Ronda, where you can savour exquisite cocktails. For a lively atmosphere, visit Café del Arte, enjoy local wines, and soak in the artistic ambiance. Don’t miss the rhythm at Club 77, known for its pulsating dance floor and fantastic DJs.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mesopotamia

To save money during your visit to Mesopotamia, Argentina, plan your trip during the off-peak months, avoiding July, August, and December when prices soar. Book your accommodation at least a month in advance, with Tuesday typically offering the best rates. Use Expedia’s search tool to filter by budget and location, and consider package deals that combine flights, hotels, and activities for extra savings. Don't forget to look for last-minute deals for spontaneous bookings, as well as eco-certified hotels for sustainable options.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Mesopotamia are , where the prices are slightly lower. This is in comparison to July to August and December, where prices are slightly higher.
  • The best time to book a hotel: Book your hotel around Mesopotamia about 1 month out to secure some of the cheapest prices. If you're the spontaneous type, Expedia's last minute deals and discounts are indicated via the green label below the price.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Mesopotamia is Tuesday. The most expensive day to stay around Mesopotamia is Monday.
  • Find cheap hotels on Expedia: Expedia's search tool enables you to specify your budget, preferred location, and additional criteria. You can arrange your search results by price, displaying the most affordable hotels at the top. Furthermore, you have the option to refine your choices by hotel category; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels available for booking.
  • Consider bundling your trip: You can save money by combining your hotel booking in Mesopotamia with your flights and activities through an Expedia package deal.

Find the best attractions near Mesopotamia

Mesopotamia, Argentina, offers a wealth of attractions, primarily centred around its stunning national parks. These points of interest are perfect for travellers seeking scenic beauty, outdoor activities, and adventure experiences. Whether you're hiking through lush landscapes or enjoying breathtaking views, there's plenty to explore in this picturesque region.

  • Portal Carambola: A stunning national park located 22.5km from Mesopotamia, offering breathtaking scenery and a variety of outdoor adventures that immerse visitors in nature’s beauty and exhilarating experiences.

Best time to go to Mesopotamia

The best time to visit Mesopotamia depends on your weather preferences. The hottest average temperature around Mesopotamia is in January and February. February is mostly sunny. The coolest average temperature around Mesopotamia is in May and July. July is mostly sunny.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January80.1°F (26.700000000000003°C)Light RainSunnyModerately HighAverage
February77.7°F (25.4°C)Light RainMostly Sunny
March72.9°F (22.700000000000003°C)Light RainMostly SunnyModerately HighAverage
April66.7°F (19.3°C)Light RainMostly SunnyAverageAverage
May59.5°F (15.3°C)Light RainMostly Sunny
June60.1°F (15.6°C)Light RainMostly Sunny
July53.4°F (11.9°C)Light RainMostly SunnyAverageSlightly High
August63.7°F (17.6°C)Light RainMostly SunnyAverageSlightly High
September60.6°F (15.9°C)Light RainMostly SunnyAverageAverage
October65.8°F (18.8°C)Light RainMostly SunnyAverageAverage
November72.3°F (22.4°C)Light RainSunnyModerately HighAverage
December77.0°F (25.0°C)Light RainSunnyAverageSlightly High

The nearest major airports for your trip to Mesopotamia

Accessing Mesopotamia, Argentina, is convenient via three major airports. Posadas (PSS-Libertador General Jose de San Martin) is approximately 222.1km away, with nearby hotel options such as La Mision Posadas Hotel and Continental Posadas Hotel, both rated at 3.5 stars. Resistencia (RES-Resistencia Intl.) is located 181.9km from Mesopotamia, offering accommodations like Del Pomar Hotel Boutique, also rated 3.5 stars. Lastly, Corrientes (CNQ-Corrientes Intl.) is around 164.2km away, with options including the 4-star Turismo Hotel Casino. Several hotels provide transportation services to their respective airports, ensuring a seamless travel experience.

Explore a world of travel with Expedia