Barrio de Santiago

Mérida

A historic stone gate with intricate carvings and two towers.
A gallery with six framed artworks on the walls and a chandelier hanging from the ceiling.
A street scene with a colorful cart, parked cars, and buildings.
A street with a restaurant, outdoor seating, and parked cars.
A staircase with ornate railings, a star-shaped light fixture, and a chessboard in the background.

Stay near popular Barrio de Santiago attractions

Casa Frederick Catherwood

9.0/10 (4 reviews)
Study a collection of 19th-century images of jungle-covered ancient ruins, which provided historians with a wealth of knowledge about the Mayans.
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Things to do

Turibus Panoramic Sightseeing Tour of Merida

Merida: Panoramic Sightseeing Bus Tour

P620
per adult
74% of travellers recommend
Merida: Panoramic Sightseeing Bus Tour
4 Cenotes Tour in Homún all inclusive from Merida

4 Cenotes Tour in Homún all inclusive from Merida

P5,084
per adult
94% of travellers recommend
4 Cenotes Tour in Homún all inclusive from Merida
Chichen Pueblos Magicos,Izamal,Valladolid & Chichikan Cenote Day Trip

Chichen Itza, Izamal & Noolha Cenote Day Trip

P7,229
per adult
92% of travellers recommend
Chichen Itza, Izamal & Noolha Cenote Day Trip
Chichen Itza, Cenote & Izamal Magic Town with Buffet Lunch from Merida

Chichen Itza, Cenote & Izamal Magic Town with Buffet Lunch from Mérida

P4,921
per adult
90% of travellers recommend
Chichen Itza, Cenote & Izamal Magic Town with Buffet Lunch from Mérida
Mérida: Panoramic Sightseeing Tour Bus Ticket with 2 Routes

Mérida México: Panoramic Sightseeing City Tour with 2 Routes

P620
per adult
80% of travellers recommend
Mérida México: Panoramic Sightseeing City Tour with 2 Routes
Isla Columpios & Progreso Day Trip

Isla Columpios, Corchito & Progreso Day Tour

P4,799
per adult
90% of travellers recommend
Isla Columpios, Corchito & Progreso Day Tour
See all activities in Mérida

Top hotels in Barrio de Santiago

Hotel Unknown

Hotel Unknown

3.5 out of 5
559 Calle 53 Mérida YUC
The price is P4,911 per night from Sep 7 to Sep 8
P4,911
P5,918 total
Sep 7 - Sep 8
includes taxes & fees
Book a stay at this spa hotel in Mérida. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Hotel Unknown
Casa Aura Hotel, Mérida

Casa Aura Hotel, Mérida

3.5 out of 5
Calle 57, 543-A, entre 66 y 68 Mérida YUC
The price is P3,167 per night from Sep 15 to Sep 16
P3,167
P3,816 total
Sep 15 - Sep 16
includes taxes & fees
Book a stay at this boutique hotel in Mérida. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (23 reviews)
"We booked a package through Expedia for a stay at Hotel Aura, and the experience was extremely disappointing from the very first day. My sister found a bed bug on the bed, and when she lifted the sheets, she discovered an actual nest of bed bugs on the mattress. When she reported this to the front ..."

Reviewed on Aug 24, 2026

Casa Aura Hotel, Mérida
Hotel Ambassador Merida

Hotel Ambassador Merida

3 out of 5
Calle 59 No.546 X 68 Mérida YUC
The price is P2,042 per night from Sep 7 to Sep 8
P2,042
P2,460 total
Sep 7 - Sep 8
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (1,005 reviews)
"Está bueno por el precio. El hotel es viejito y no hay mucho mantenimiento de las áreas o habitaciones. Y su esperas encontrar una habitación moderna y con todo funcional no es este hotel. Por ej: no funcionaba el TV, el agua caliente de la ducha era fría, no encontrarás ni plancha ni secador de ..."

Reviewed on Aug 18, 2026

Hotel Ambassador Merida
Casa Loreto 1893

Casa Loreto 1893

5 out of 5
619 Calle 59 Mérida
The price is P8,562 per night from Oct 3 to Oct 4
P8,562
P10,317 total
Oct 3 - Oct 4
includes taxes & fees
Book a stay at this luxury hotel in Mérida. Enjoy free WiFi, free parking, and room service. Popular attractions Paseo de Montejo and Plaza Altabrisa are located ...
9.8/10 Exceptional! (171 reviews)
"Room was great staff friendly just as I expected. Would totally stay there again"

Reviewed on Aug 27, 2026

Casa Loreto 1893
Hotel Casa 57

Hotel Casa 57

3 out of 5
539 C. 57 Centro Mérida Yuc.
The price is P2,386 per night from Sep 7 to Sep 8
P2,386
P2,875 total
Sep 7 - Sep 8
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (421 reviews)
"Everything was great during my entire stay"

Reviewed on Aug 14, 2026

Hotel Casa 57
Casona 61 Boutique Hotel

Casona 61 Boutique Hotel

3.5 out of 5
Calle 61 entre 66 y 68 Mérida YUC
Stay at this hotel in Mérida. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
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Casona 61 Boutique Hotel
See all 1,395 properties in Barrio de Santiago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Barrio de Santiago

Find the best Barrio de Santiago areas and neighborhoods for the activities you enjoy most.
A historic building with a clock tower, a street with light trails from moving vehicles, and a red building with a sign.

Mérida Centro

Mérida Centro is popular for its abundant dining options, and if you're looking for more to see and do, you might think about a trip to Plaza Grande or Parque Zoológico del Centenario.

A sunset over a body of water with a rocky shoreline.
Photo by Tony Lozano
Open Photo by Tony Lozano

Chelem

You might make a stop by Chelem Park while you're exploring Chelem.

A historic building with ornate architecture, palm trees, and well-maintained landscaping.
Photo by Tony Lozano
Open Photo by Tony Lozano

Zona Paseo Montejo

While visiting Zona Paseo Montejo, you might make a stop by sights like Paseo 60 and Paseo de Montejo.

A row of boats on a beach with a sunset in the background.
Photo by Alex Vizcaino
Open Photo by Alex Vizcaino

Chicxulub Puerto

Travelers like the beaches in Chicxulub Puerto, and Playa Uaymitun is a top attraction you might want to visit.

A beach with wooden posts and a sunset sky.

Chuburna Puerto

Plan a visit to nearby attractions like Chelem Park while you're exploring Chuburna Puerto and the larger area.

Barrio de Santiago