Hotels near Lewis and Clark Trail Trailhead

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Our top choices for Lewis and Clark Trail Trailhead hotels

Lobby
Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
3.2 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (1004)
"Wonderful stay. Checkin was easy and host was very accommodating. "
United States
Teresa
The price is P4,632
P5,464 total
includes taxes & fees
Dec 28 - Dec 29
Sleep Inn & Suites O'Fallon MO - Technology Drive
Exterior
Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
3.2 km from Lewis and Clark Trail Trailhead
8.6 out of 10, Excellent, (847)
"A very nice stay with very pleasant staff"
United States
Clifford
The price is P5,346
P6,306 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express St. Louis West - O'Fallon by IHG
Exterior
Staybridge Suites O'Fallon Chesterfield by IHG

Staybridge Suites O'Fallon Chesterfield by IHG

Staybridge Suites O'Fallon Chesterfield by IHG
3.0 star property
3.2 km from Lewis and Clark Trail Trailhead
8.4 out of 10, Very Good, (409)
"Simple excellent place to stay"
United States
Hussam
The price is P6,442
P7,598 total
includes taxes & fees
Dec 28 - Dec 29
Staybridge Suites O'Fallon Chesterfield by IHG
Property amenity
TownePlace Suites by Marriott St. Louis Chesterfield

TownePlace Suites by Marriott St. Louis Chesterfield

TownePlace Suites by Marriott St. Louis Chesterfield
3.0 star property
5.6 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (271)
"lady at the desk that works 2 jobs 7 days a wk DAMN!!! Shes great."
United States
nigel e
The price is P6,756
P7,929 total
includes taxes & fees
Dec 28 - Dec 29
TownePlace Suites by Marriott St. Louis Chesterfield
Lobby
Residence Inn by Marriott O'Fallon

Residence Inn by Marriott O'Fallon

Residence Inn by Marriott O'Fallon
3.0 star property
3.6 km from Lewis and Clark Trail Trailhead
8.4 out of 10, Very Good, (454)
"Love the stay great for families!"
United States
jeriece
The price is P6,991
P8,246 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Residence Inn by Marriott O'Fallon
Lobby sitting area
Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO
3.0 star property
7.1 km from Lewis and Clark Trail Trailhead
8.8 out of 10, Excellent, (719)
"Clean room, quiet"
United States
Laura
The price is P5,547
P6,577 total
includes taxes & fees
Jan 23 - Jan 24, 2026
Hilton Garden Inn St. Louis/O'Fallon MO
Hypo-allergenic bedding, desk, laptop workspace, blackout drapes
Comfort Inn & Suites Chesterfield - St. Louis

Comfort Inn & Suites Chesterfield - St. Louis

Comfort Inn & Suites Chesterfield - St. Louis
2.5 star property
6.6 km from Lewis and Clark Trail Trailhead
8.0 out of 10, Very Good, (1000)
"Great place to stay"
United States
Dawn
The price is P4,482
P5,421 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Comfort Inn & Suites Chesterfield - St. Louis
Free daily full breakfast
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
2.5 star property
10.3 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (1004)
"Great hotel!"
United States
Lorelei
The price is P6,227
P7,246 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
BBQ/picnic area
Courtyard by Marriott St. Louis Chesterfield

Courtyard by Marriott St. Louis Chesterfield

Courtyard by Marriott St. Louis Chesterfield
3.0 star property
10.9 km from Lewis and Clark Trail Trailhead
9.0 out of 10, Wonderful, (578)
"Very clean hotel with great staff "
United States
brad
The price is P6,580
P7,656 total
includes taxes & fees
Jan 24 - Jan 25, 2026
Courtyard by Marriott St. Louis Chesterfield
Front of property - evening/night
Hampton Inn & Suites St. Louis/Chesterfield

Hampton Inn & Suites St. Louis/Chesterfield

Hampton Inn & Suites St. Louis/Chesterfield
3.5 star property
10.9 km from Lewis and Clark Trail Trailhead
8.8 out of 10, Excellent, (847)
"It was great, clean, quiet and friendly! "
United States
Lisa
The price is P5,973
P6,951 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hampton Inn & Suites St. Louis/Chesterfield
Exterior
WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
13.6 km from Lewis and Clark Trail Trailhead
9.4 out of 10, Exceptional, (26)
"Very nice place. Clean room. Staff was excellent. "
United States
Richard
The price is P4,347
P5,147 total
includes taxes & fees
Dec 29 - Dec 30
WoodSpring Suites St Peters-OFallon
Desk, iron/ironing board, free WiFi, bed sheets
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
12.5 km from Lewis and Clark Trail Trailhead
6.8 out of 10, (999)
"Very run down and trash around the property, but the room was clean and comfortable for our one night stop. Convenience of the location"
United States
Natalie
The price is P3,845
P4,535 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Super 8 by Wyndham O'Fallon MO/St. Louis Area
Ballroom
The Wildwood Hotel

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
14.7 km from Lewis and Clark Trail Trailhead
9.2 out of 10, Wonderful, (1614)
"Great place!"
United States
Biju
The Wildwood Hotel
Exterior
Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
14.8 km from Lewis and Clark Trail Trailhead
9.6 out of 10, Exceptional, (1037)
"Absolutely amazing stay very nice play our family stays there every time very kid friendly"
United States
Matthew
The price is P7,637
P8,857 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Drury Plaza Hotel St. Louis Chesterfield
Property amenity
Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield
3.0 star property
12.4 km from Lewis and Clark Trail Trailhead
9.6 out of 10, Exceptional, (199)
"Very clean and safe place, wonderful location "
United States
Ashley
The price is P11,103
P12,989 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Residence Inn by Marriott St. Louis Chesterfield
Breakfast, lunch, dinner served; American cuisine
Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
3.0 star property
14.9 km from Lewis and Clark Trail Trailhead
9.6 out of 10, Exceptional, (1001)
"Wonderful staff, easy parking, nice breakfast, very comfortable room."
United States
Carole
The price is P7,226
P8,381 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hyatt Place St. Louis/Chesterfield
Property amenity
Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
15 km from Lewis and Clark Trail Trailhead
9.4 out of 10, Exceptional, (1002)
"Great hotel! Clean, friendly staff, wonderful amenities!"
United States
Susan
The price is P6,462
P7,428 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Drury Inn & Suites St. Louis St. Peters
Lobby
Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
2.5 star property
13.4 km from Lewis and Clark Trail Trailhead
9.2 out of 10, Wonderful, (374)
"Room was very clean and great amenities. Breakfast was decent. Great value"
United States
Marcus
The price is P5,933
P7,174 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Holiday Inn Express & Suites St Peters by IHG
Lobby
Relax Inn Saint Charles

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
18.2 km from Lewis and Clark Trail Trailhead
6.6 out of 10, (1005)
"Great place to stay "
United States
Askar
The price is P3,701
P4,253 total
includes taxes & fees
Dec 28 - Dec 29
Relax Inn Saint Charles
Lobby
AC Hotel by Marriott St. Louis Chesterfield

AC Hotel by Marriott St. Louis Chesterfield

AC Hotel by Marriott St. Louis Chesterfield
3.5 star property
13.8 km from Lewis and Clark Trail Trailhead
9.2 out of 10, Wonderful, (245)
"Newer hotel, very clean, up to date and in nice area. "
United States
Johnny
The price is P7,461
P8,654 total
includes taxes & fees
Jan 4 - Jan 5, 2026
AC Hotel by Marriott St. Louis Chesterfield
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Lewis and Clark Trail Trailhead Hotel Reviews

Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur

10/10 Excellent
"Super clean room, great parking and quiet area. Staff at front desk was very helpful. "
Janice 1-night trip
Posted 4 days ago
Courtyard by Marriott St Louis Creve Coeur

Hotels near other Lewis and Clark Trail Trailhead attractions

Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

August A. Busch Memorial Conservation Area

Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savor the top-notch restaurants.
See properties
9-11 memorial in New York

9-11 Memorial

3.9/5 (30 reviews)
Learn about the local history of O'Fallon when you spend time at 9-11 Memorial. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Lewis and Clark Trail Trailhead?
Lewis and Clark Trail Trailhead is located in Weldon Spring Heights. You'll find 29 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay close to Lewis and Clark Trail Trailhead?
The Wildwood Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. You'll find it 9.1 mi (14.7 km) from Lewis and Clark Trail Trailhead. Other good options around the area include Drury Plaza Hotel St. Louis Chesterfield and Hyatt Place St. Louis/Chesterfield.
How many hotels can I expect to find near Lewis and Clark Trail Trailhead?
Expedia has 29 hotels and other accommodations a few miles from Lewis and Clark Trail Trailhead.
If I need to cancel the hotel reservation for my stay near Lewis and Clark Trail Trailhead, will I receive a refund?
Yes, most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available near Lewis and Clark Trail Trailhead.
What can I see and do near Lewis and Clark Trail Trailhead?
Explore nature at August A. Busch Memorial Conservation Area and Hamburg Trail Trailhead. Missouri Bluffs Golf Course, Golf Headquarters, and Babler State Park are worth a stop while you're in the area. St. Louis Premium Outlets and 9-11 Memorial are both worth a visit while you're checking out the area.