Top 10 Hotels Near Lewis and Clark Trail Trailhead in St. Louis for 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Lewis and Clark Trail Trailhead hotels

A hotel room with a bed, a sofa, a coffee table, and wall art.

A Sleep Inn & Suites hotel with a modern brick facade, a covered entrance, and a parking lot.

A hotel lobby with a reception desk, seating area, and a large potted plant.

A restaurant with wooden tables and chairs, a blue wall with white floral patterns, and a counter with a coffee machine.

1. Sleep Inn & Suites O'Fallon MO - Technology Drive

3.2 km from Lewis and Clark Trail Trailhead

Tim

P5,173

P6,102 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

A reception desk with a modern design, featuring a blue geometric wall and a wooden finish.

A Holiday Inn Express hotel with a brick facade, a covered entrance, and a clear sky.

A modern hotel room with a desk, chair, and a large mirror.

2. Holiday Inn Express St. Louis West - O'Fallon by IHG

3.2 km from Lewis and Clark Trail Trailhead

Greg

P5,574

P6,575 total

includes taxes & fees

Oct 11 - Oct 12

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

A modern hotel entrance with a glass canopy, large windows, and a brick facade.

A swimming pool with a tiled deck, a sunlit room with a view, and a seating area with chairs.

A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract painting on the wall.

3. Hyatt Place St. Louis/Chesterfield

14.9 km from Lewis and Clark Trail Trailhead

Chelsea

P7,655

P8,878 total

includes taxes & fees

Oct 26 - Oct 27

An outdoor patio area with wicker furniture and a central fire feature.

A hotel room with a bed, a sofa, a desk, and a chair.

A modern hotel lobby with a reception desk, seating area, and a television screen displaying a map.

A modern hotel lobby with a bar area, seating arrangements, and a reception desk.

4. Courtyard by Marriott St. Louis Chesterfield

10.9 km from Lewis and Clark Trail Trailhead

Kelly

P7,567

P8,805 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor patio area with a stone fire pit, wicker furniture, and a covered seating area with a view of the building's interior.

A hotel room with a sofa, a side table, a lamp, a flat-screen TV, and a bed with a red blanket.

A modern kitchen with wooden cabinets, a stainless steel countertop, and various appliances including a coffee maker and a rice cooker.

A multi-story hotel with a brick facade, a covered outdoor seating area with a fire feature, and a sign indicating it is a Marriott property.

5. TownePlace Suites by Marriott St. Louis Chesterfield

5.8 km from Lewis and Clark Trail Trailhead

Bobbi jo

P8,017

P9,409 total

includes taxes & fees

Oct 6 - Oct 7

A spacious lobby with a central round table, two sofas, and a chandelier.

A hotel room with two beds, a patterned wall, and a view of the city through sheer curtains.

An indoor swimming pool area with clear signage indicating a depth of 3 feet and a no diving warning.

A Drury Plaza hotel with a modern design, featuring a curved facade, large windows, and a Drury Plaza sign on the top.

6. Drury Plaza Hotel St. Louis Chesterfield

14.8 km from Lewis and Clark Trail Trailhead

Cassandra

P8,156

P9,460 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor patio with a built-in grill, seating area, and stone walls.

A modern lobby with a stone accent wall, a flat-screen TV, a reception desk, seating area with sofas and ottomans, and a patterned rug.

An indoor swimming pool with clear glass walls, sunlit seating area, and lifeguard station.

A multi-story hotel with a parking lot in front.

7. Residence Inn by Marriott St. Louis Chesterfield

12.4 km from Lewis and Clark Trail Trailhead

Brandon

P11,858

P13,873 total

includes taxes & fees

Oct 2 - Oct 3

A modern kitchen area with a breakfast bar, a coffee machine, and a refrigerator displaying menu options.

A hotel room with two beds, a blue sofa, a small table, and a kitchenette.

A Holiday Inn Express & Suites building with a brick facade, a covered entrance, and a numbered address.

A coffee station with two coffee machines and a display of coffee pods and cups.

8. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

10.3 km from Lewis and Clark Trail Trailhead

Steven

P6,964

P8,104 total

includes taxes & fees

Oct 25 - Oct 26

A hotel reception area with a counter, coffee machines, a refrigerated display, and artwork on the wall.

A hotel room with a bed, desk, TV, and a view of the outdoors.

An indoor swimming pool with clear water, a diving board, and a seating area with tables and chairs.

A snack bar with shelves of chips, candies, and bottled water.

9. Fairfield Inn & Suites by Marriott St. Louis Chesterfield

15.6 km from Lewis and Clark Trail Trailhead

Thomas Kent

P6,708

P7,780 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with two beds, a desk, a chair, a TV, and a large window.

A modern hotel room with a sofa, a small table, a yellow ottoman, a wooden desk, a flat-screen TV, and a bathtub.

A brick building with a sign reading "Comfort Inn & Suites."

A spacious lobby with a blue sofa set, a reception desk, and a modern chandelier.

10. Comfort Inn & Suites Chesterfield - St. Louis

6.6 km from Lewis and Clark Trail Trailhead

Donna

P5,081

P6,132 total

includes taxes & fees

Oct 11 - Oct 12

A multi-story hotel with a central entrance featuring a covered patio area.

A hotel room with a desk, chair, sofa, and a window with curtains.

A hotel room with a sofa, armchair, bedside table, lamp, TV, and a bed with patterned bedding.

A hotel lobby with a sectional sofa, a fireplace, a flat-screen TV, and framed artwork on the walls.

11. Staybridge Suites O'Fallon Chesterfield by IHG

3.2 km from Lewis and Clark Trail Trailhead

Norman

P6,952

P8,200 total

includes taxes & fees

Oct 8 - Oct 9

A hotel with a prominent tower, a fountain in the courtyard, and a well-maintained garden.

A hotel room with a large bed, a bedside lamp, a telephone, a mirror, and a bathroom with a sink and towel rack.

A formal dining table set for six with a vase of white flowers, candles, and a view of buildings through large windows.

A modern bathroom with a large mirror, white vanity, and a bathtub.

12. The Wildwood Hotel

14.7 km from Lewis and Clark Trail Trailhead

Ramona

P5,719

P6,661 total

includes taxes & fees

Oct 21 - Oct 22

A spacious lobby with a high ceiling, a central seating area with sofas and a coffee table, and a large window providing natural light.

A hotel with a covered entrance, multiple flags, and a well-maintained lawn.

A spacious lobby with a fireplace, comfortable seating, a large painting, and a view of the kitchen area.

A shop with a variety of snacks and beverages, including a refrigerated section with drinks and a display of packaged snacks.

13. Hilton Garden Inn St. Louis/O'Fallon MO

7.1 km from Lewis and Clark Trail Trailhead

Kassie

P6,779

P8,038 total

includes taxes & fees

Oct 18 - Oct 19

An outdoor patio area with wicker furniture, a stone fire pit, and a building in the background.

A Courtyard by Marriott hotel with a modern design, multiple floors, and a flat roof.

A modern bar area with wooden furniture, a counter with a menu, and a seating area with tables and chairs.

A modern lobby with a sofa, armchairs, a coffee table, and a bookshelf.

14. Courtyard by Marriott St. Louis St. Peters

17.3 km from Lewis and Clark Trail Trailhead

Krischel

P7,553

P9,071 total

includes taxes & fees

Oct 4 - Oct 5

A courtyard with a central seating area, surrounded by trees and a building with a pitched roof.

A reception desk with a "WELCOME TO THE SHOW ME STATE" sign, a wooden counter, and a Hilton Honors sign.

A modern dining area with a long table, multiple chairs, and pendant lighting.

A store interior with a 'Treats' sign, snack shelves, and a chalkboard with a welcome message.

15. Hampton Inn & Suites St. Louis/Chesterfield

10.9 km from Lewis and Clark Trail Trailhead

Vijay

P7,735

P9,001 total

includes taxes & fees

Sep 27 - Sep 28

An outdoor seating area with a table and chairs, a fire feature, and a brick wall.

A hotel lobby with a seating area, tables, and a TV screen.

A bar area with a counter, stools, and shelves with bottles and glasses.

A modern hotel with a flat roof, large windows, and a prominent signage for 'SPRINGHILL SUITES.'

16. SpringHill Suites by Marriott St. Louis Chesterfield

15.6 km from Lewis and Clark Trail Trailhead

Omar

P7,675

P8,902 total

includes taxes & fees

Oct 4 - Oct 5

A spacious lobby with a stone fireplace, seating area, and a bar with high stools.

A hotel pantry stocked with beverages and snacks, a refrigerated display case, and a sign reading "The Market".

A modern living room with a fireplace, a flat-screen TV, a sofa, a coffee table, and a dining area.

A hotel lobby with a seating area featuring two armchairs, a round coffee table, and a flat-screen TV mounted on a wooden wall.

17. Residence Inn by Marriott O'Fallon

3.6 km from Lewis and Clark Trail Trailhead

Gerald

P8,205

P9,677 total

includes taxes & fees

Oct 11 - Oct 12

A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase leading to an upper level.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A modern lobby with a reception desk, seating area, and a dining section.

A hotel room with two beds, a desk, a blue sofa, and a TV.

18. Holiday Inn Express & Suites St Peters by IHG

13.4 km from Lewis and Clark Trail Trailhead

Serah

P6,964

P8,389 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with a high ceiling, a dining area, and a seating area with sofas and a coffee table.

A spacious lobby with a blue sofa, round coffee table, and blue chairs. There is a reception desk and a seating area with a high ceiling and large windows.

An indoor swimming pool with clear blue water, a tiled floor, and a ceiling with square vents.

A hotel room with a bed, a dresser, a nightstand with a lamp, a framed map on the wall, and a carpeted floor.

19. Drury Inn & Suites St. Louis St. Peters

15 km from Lewis and Clark Trail Trailhead

Tiffany

P6,901

P7,933 total

includes taxes & fees

Oct 4 - Oct 5

A modern hotel with a prominent entrance, a landscaped courtyard, and a well-lit facade.

A modern conference room with a large table, four chairs, a computer, and a bookshelf with books and a framed picture.

A spacious lobby with a sectional sofa, a coffee table, and a round table with chairs. There is a large abstract painting on the wall and a staircase in the background.

An outdoor patio area with a stone wall, seating, and a table.

20. AC Hotel by Marriott St. Louis Chesterfield

13.8 km from Lewis and Clark Trail Trailhead

Harold

P9,976

P11,572 total

includes taxes & fees

Oct 11 - Oct 12

View all properties

Compare popular hotels close to Lewis and Clark Trail Trailhead

Property	Property class	Guest rating
Sleep Inn & Suites O'Fallon MO - Technology Drive	9.0 Wonderful 1,127 reviews	View
Holiday Inn Express St. Louis West - O'Fallon by IHG	8.6 Excellent 997 reviews	View
Hyatt Place St. Louis/Chesterfield	9.6 Exceptional 1,006 reviews	View
Courtyard by Marriott St. Louis Chesterfield	9.0 Wonderful 672 reviews	View
TownePlace Suites by Marriott St. Louis Chesterfield	9.0 Wonderful 329 reviews	View

Top Lewis and Clark Trail Trailhead Hotel Reviews

Pear Tree Inn St. Louis Airport

8/10 Good

"The breakfast was adequate, but not impressive. They had no tea. The microwave was old and had limited power. The bathroom sinks have a faucet off to the side of the sink. It makes it less convenient to use for washing."

Ameristar Casino Resort and Spa

8/10 Good

"Clean room, check in was great."

WoodSpring Suites St Peters-OFallon

10/10 Excellent

"Everything good"

Comfort Suites St Charles - St Louis

10/10 Excellent

"Overall good experience; excellent breakfast"

Drury Inn & Suites St. Louis St. Peters

10/10 Excellent

"Really enjoyed all of it and the staff was top-notch. The cleanliness was great and it was a modern, well-laid-out hotel."

The Wildwood Hotel

10/10 Excellent

"Very nice hotel. Only concern is the single elevator, since the front desk is on a different level than the bulk of the rooms. Makes for congestion in the morning when housecleaning staff are using it."

Drury Plaza Hotel St. Louis St. Charles

8/10 Good

"Staff is always so friendly at this hotel"

Embassy Suites by Hilton St. Louis St. Charles

10/10 Excellent

"Very friendly staff"

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

8/10 Good

"Breakfast was ok. The cinnamon rolls were outstanding. Room was great, staff very nice and the pool was also good."

Other attractions near Lewis and Clark Trail Trailhead

A wooden dock extending into a pond with lily pads, surrounded by lush greenery and a clear blue sky.

August A. Busch Memorial Conservation Area

8.6/10 (7 reviews)

Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savor the top-notch restaurants.

See properties

A chain-link fence with a red sign that reads "REMEMBRANCE DAY" and a date "09-11-01".

9-11 Memorial

7.6/10 (44 reviews)

Learn about the local history of O'Fallon when you spend time at 9-11 Memorial. While in this family-friendly area, you can savor the top-notch restaurants.

See properties

Weldon Spring Site Interpretive Center

8.2/10 (14 reviews)

You can spend time browsing the exhibits at Weldon Spring Site Interpretive Center during your trip to Weldon Spring Heights. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants.

See properties

Hamburg Trail Trailhead

You can take time to visit Hamburg Trail Trailhead during your travels to Hamburg.

See properties

Missouri Bluffs Golf Course

7.6/10 (40 reviews)

Enjoy a round of golf in Weldon Spring Heights at Missouri Bluffs Golf Course. Experience the great live music or attend a sporting event in this family-friendly area.

See properties

St. Louis Premium Outlets

8.8/10 (369 reviews)

You can enjoy retail therapy at St. Louis Premium Outlets during your stay in Chesterfield. Discover the top-notch restaurants and great live music in this family-friendly area.

See properties

Golf Headquarters Family Golfplex

You can take time to visit Golf Headquarters Family Golfplex during your travels to O'Fallon. Visit the shops in this family-friendly area, or simply enjoy its restaurants.

See properties

Babler State Park

8.6/10 (59 reviews)

You can take time to visit Babler State Park during your travels to Chesterfield. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants.

See properties

Frequently asked questions

What's the area like around Lewis and Clark Trail Trailhead?

Lewis and Clark Trail Trailhead is located in Weldon Spring Heights. You'll find 27 hotels and other accommodations within a few miles for a convenient home base.

What's the best place to stay close to Lewis and Clark Trail Trailhead?

Sleep Inn & Suites O'Fallon MO - Technology Drive is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 2 mi (3.2 km) from Lewis and Clark Trail Trailhead. Other good options around the area include Holiday Inn Express & Suites St. Louis - Chesterfield by IHG and Sonesta ES Suites St. Louis - Chesterfield.

How many hotels can I expect to find near Lewis and Clark Trail Trailhead?

Expedia has 27 hotels and other accommodations a few miles from Lewis and Clark Trail Trailhead.

If I need to cancel the hotel reservation for my stay near Lewis and Clark Trail Trailhead, will I receive a refund?

Yes, most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available near Lewis and Clark Trail Trailhead.

What can I see and do near Lewis and Clark Trail Trailhead?

Explore nature at August A. Busch Memorial Conservation Area and Hamburg Trail Trailhead. Missouri Bluffs Golf Course, Babler State Park, and Golf Headquarters Family Golfplex are worth a stop while you're in the area. St. Louis Premium Outlets and 9-11 Memorial are both worth a visit while you're checking out the area.

Hotels near Lewis and Clark Trail Trailhead

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lewis and Clark Trail Trailhead hotels

1. Sleep Inn & Suites O'Fallon MO - Technology Drive

2. Holiday Inn Express St. Louis West - O'Fallon by IHG

3. Hyatt Place St. Louis/Chesterfield

4. Courtyard by Marriott St. Louis Chesterfield

5. TownePlace Suites by Marriott St. Louis Chesterfield

6. Drury Plaza Hotel St. Louis Chesterfield

7. Residence Inn by Marriott St. Louis Chesterfield

8. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

9. Fairfield Inn & Suites by Marriott St. Louis Chesterfield

10. Comfort Inn & Suites Chesterfield - St. Louis

11. Staybridge Suites O'Fallon Chesterfield by IHG

12. The Wildwood Hotel

13. Hilton Garden Inn St. Louis/O'Fallon MO

14. Courtyard by Marriott St. Louis St. Peters

15. Hampton Inn & Suites St. Louis/Chesterfield

16. SpringHill Suites by Marriott St. Louis Chesterfield

17. Residence Inn by Marriott O'Fallon

18. Holiday Inn Express & Suites St Peters by IHG

19. Drury Inn & Suites St. Louis St. Peters

20. AC Hotel by Marriott St. Louis Chesterfield

Compare popular hotels close to Lewis and Clark Trail Trailhead

Top Lewis and Clark Trail Trailhead Hotel Reviews

Pear Tree Inn St. Louis Airport

Ameristar Casino Resort and Spa

WoodSpring Suites St Peters-OFallon

Comfort Suites St Charles - St Louis

Drury Inn & Suites St. Louis St. Peters

The Wildwood Hotel

Drury Plaza Hotel St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Other attractions near Lewis and Clark Trail Trailhead

August A. Busch Memorial Conservation Area

9-11 Memorial

Weldon Spring Site Interpretive Center

Hamburg Trail Trailhead

Missouri Bluffs Golf Course

St. Louis Premium Outlets

Golf Headquarters Family Golfplex

Babler State Park

Frequently asked questions