La Serena Vacation Rentals

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Check prices for these dates

Tonight
Dec 26 - Dec 27
Tomorrow
Dec 27 - Dec 28
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Our top choices for La Serena vacation rentals

Front of property
Apart Hotel y Cabañas Vegasur

Aparthotel in La Serena

Apart Hotel y Cabañas Vegasur
3.0 star property
8.6 out of 10, Excellent, (93)
"LIMPIEZA BUENA, NO TENGO REPAROS AL RESPECTO."
Chile
Martin
Apart Hotel y Cabañas Vegasur
Exterior
Cabañas Yunkai

Cabin in Vicuña

Cabañas Yunkai
3.0 star property
The price is P4,976
P4,976 total
Dec 30 - Dec 31
Cabañas Yunkai
Exterior
Parcela Los Nonos

Cabin in Vicuña

Parcela Los Nonos
3.0 star property
Parcela Los Nonos
Front of property
IndomitoElqui

Cabin in Paiguano

IndomitoElqui
2.0 star property
10.0 out of 10, Exceptional, (1)
The price is P4,215
P6,166 total
Jan 24 - Jan 25, 2026
IndomitoElqui
32-inch flat-screen TV with cable channels, first-run movies
Domos Dream hotel cabañas

Camping in La Serena

Domos Dream hotel cabañas
2.0 star property
8.6 out of 10, Excellent, (4)
"It was far away."
Mexico
Sergio
The price is P4,659
P4,659 total
Dec 30 - Dec 31
Domos Dream hotel cabañas
Private kitchen
Oceana Suites - Laguna Aculeo

Vacation Home in Coquimbo

Oceana Suites - Laguna Aculeo
2.0 star property
The price is P8,824
P17,648 total
Dec 30 - Dec 31
Oceana Suites - Laguna Aculeo
Private kitchen
Depto Serena Golf

Apartment in La Serena

Depto Serena Golf
2.0 star property
The price is P13,660
P17,562 total
Dec 27 - Dec 28
Depto Serena Golf
3 outdoor pools, open 11:00 AM to 8:00 PM, pool umbrellas
Cabaña Villa Los Plátanos

Cabin in La Serena

Cabaña Villa Los Plátanos
3.0 star property
10.0 out of 10, Exceptional, (2)
The price is P4,877
P4,877 total
Dec 27 - Dec 28
Cabaña Villa Los Plátanos
Exterior
Yunkai Home

Apartment in Vicuña

Yunkai Home
2.0 star property
The price is P5,854
P5,854 total
Jan 25 - Jan 26, 2026
Yunkai Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Serena Hotel Reviews

Hotel Club La Serena

Hotel Club La Serena

10/10 Excellent
"Todo excelente, ubicación"
Marcos 3-night trip
Posted 4 days ago
Hotel Club La Serena

Find out more about La Serena

Search for holiday rentals in La Serena on Expedia! You can easily find your home rentals, villas, holiday apartments in La Serena using one of the methods below:

  • View our selection of featured holiday rentals in La Serena
  • Use the map to find apartments and other holiday homes in the La Serena neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in La Serena while they last

Look no further and take a look at our great range of rental properties in La Serena!

Frequently asked questions

Can I find a vacation rental in La Serena?

Yes, we give you a choice of vacation rentals in La Serena near Jardin del Corazon, or you can go with a more remote option if you're looking for a relaxing stay. La Serena is known for its sightseeing tours and spas. Make sure you have time to check out the casinos while you're in the area.

How many vacation rentals will I find in La Serena?

With 17 Expedia vacation rentals, you're sure to find just the right place for your La Serena stay.

What can I see and do in La Serena?

Cultural attractions include President Gabriel González Videla Regional History Museum and Casa Gabriel Gonzalez Videla Historical Museum, whereas Kokoro No Niwa Japanese Garden and El Faro Beach are a couple of picturesque spots to enjoy the outdoors. While here, Mall Plaza La Serena and La Serena Lighthouse are other places worth a visit.

What are vacation rentals like in La Serena?

Vacation rentals are private accommodations you can reserve for a short or long stay in La Serena. Vacation rentals provide amenities like kitchens and laundry facilities so you'll be comfy for your stay. If you're concerned about a sanitized environment, a vacation rental can offer a sense of security away from public hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great option for a family trip.