La Mesilla Hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending La Mesilla hotels

Holiday Inn Express & Suites Los Alamos Entrada Park by IHG

2.5 star property
8.8 out of 10, Excellent, (705)
"Not that there's a TON of options for you in Los Alamos, but this hotel is very nice, great staff, good food. Can't go wrong here!"
The price is P6,954
P7,792 total
includes taxes & fees
Sep 5 - Sep 6
Holiday Inn Express & Suites Los Alamos Entrada Park by IHG

Wingate by Wyndham Los Alamos

2.5 star property
8.0 out of 10, Very Good, (543)
"Such friendly staff and very clean!"
The price is P7,130
P7,990 total
includes taxes & fees
Sep 6 - Sep 7
Wingate by Wyndham Los Alamos

Days Inn by Wyndham Espanola

2.0 star property
5.8 out of 10, (574)
"Very nice staff, room was already cooled down and you could get anywhere quickly from that location."
The price is P6,054
P7,004 total
includes taxes & fees
Sep 18 - Sep 19
Days Inn by Wyndham Espanola

Hotel Glorieta

3.5 star property
7.8 out of 10, Good, (1002)
"Great place to stay!"
The price is P6,555
P9,191 total
includes taxes & fees
Sep 2 - Sep 3
Hotel Glorieta

Rodeway Inn

2.0 star property
6.2 out of 10, (450)
"The young woman who checked us in was very friendly "
The price is P4,832
P5,590 total
includes taxes & fees
Aug 27 - Aug 28
Rodeway Inn

Ohkay Casino Resort Hotel

2.5 star property
8.0 out of 10, Very Good, (764)
"It was clean felt safe quiet. Room was comfortable. "
Ohkay Casino Resort Hotel

Hilton Santa Fe Buffalo Thunder

4.0 star property
8.4 out of 10, Very Good, (1001)
"Excellent place to stay. "
The price is P9,986
P11,414 total
includes taxes & fees
Sep 1 - Sep 2
Hilton Santa Fe Buffalo Thunder

Homewood Suites by Hilton Santa Fe-North

3.0 star property
9.2 out of 10, Wonderful, (1000)
"Beautiful hotel ,,great service,n great food "
The price is P7,703
P8,805 total
includes taxes & fees
Aug 31 - Sep 1
Homewood Suites by Hilton Santa Fe-North

Hampton Inn & Suites Los Alamos White Rock

2.5 star property
9.0 out of 10, Wonderful, (643)
"Great place!!"
The price is P6,496
P7,280 total
includes taxes & fees
Sep 4 - Sep 5
Hampton Inn & Suites Los Alamos White Rock

Motel 6 Espanola, NM

2.0 star property
6.4 out of 10, (504)
"Great new staff and management"
The price is P5,072
P5,868 total
includes taxes & fees
Sep 2 - Sep 3
Motel 6 Espanola, NM

Cities Of Gold Casino

3.0 star property
8.0 out of 10, Very Good, (1042)
"great location, front desk staff mmm, all others were great, nice resources within a mile"
The price is P4,806
P5,493 total
includes taxes & fees
Sep 18 - Sep 19
Cities Of Gold Casino

Four Seasons Resort Rancho Encantado Santa Fe

5.0 star property
9.4 out of 10, Exceptional, (262)
"Food options were good, but limited. The scenery was breathtaking as well as the nearby Santa Fe and the tours we took to the Indian reservation and Los Alamos"
The price is P41,122
P49,363 total
includes taxes & fees
Sep 7 - Sep 8
Four Seasons Resort Rancho Encantado Santa Fe

Bishop's Lodge Auberge Resorts Collection

5.0 star property
9.4 out of 10, Exceptional, (78)
"Great place "
Bishop's Lodge Auberge Resorts Collection

The Inn at the Delta

3.0 star property
9.4 out of 10, Exceptional, (1000)
"The Inn at the Delta was one of the best stays we've had. The gorgeous details in the room, the lush grounds, and the incredible staff combined made us wish we had booked a (much) longer stay!"
The Inn at the Delta

Casa Escondida Bed & Breakfast

3.0 star property
9.4 out of 10, Exceptional, (245)
"Incredible B&B just outside of town, nature and mountains along with clean comfortable room and amazing breakfast "
The price is P9,330
P10,414 total
includes taxes & fees
Aug 21 - Aug 22
Casa Escondida Bed & Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about La Mesilla

Check out Cities of Gold Casino and Towa Golf Resort—just a couple of the sights around La Mesilla.

Top La Mesilla Hotel Reviews

Frequently asked questions

What's the best place for a stay in La Mesilla?

Located 5 mi (8 km) from the heart of La Mesilla, Cities Of Gold Casino is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Hilton Santa Fe Buffalo Thunder and The Lodge at Santa Fe. See all available top hotels, or vacation rentals in La Mesilla.

What are some of the best vacation home rentals in La Mesilla?

Cielo Grande: Located near La Mesilla, this vacation home rental is located near the beach and has a fireplace, a balcony, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in La Mesilla.

If I need to cancel my hotel reservation in La Mesilla, will I receive a refund?

Yes, most hotel room reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesilla.

Where can I learn more about changing or cancelling my trip to La Mesilla?

To access more information about updating your trip to La Mesilla or cancelling it, head over to our customer service page.

What is staying in La Mesilla like?

Visitors are sure to enjoy all that La Mesilla has to offer. There are 307 hotels and other accommodations in the surrounding area. Find out more about La Mesilla.

What should I do while I'm visiting La Mesilla?

Places to visit in the wider area include Cities of Gold Casino, Towa Golf Resort, and Buffalo Thunder Resort and Casino. You'll also find Santuario de Chimayo and Lowlows Lowrider Art Place in the area. Check out what more to see and do in Expedia's La Mesilla guide.

What's the weather like in La Mesilla?

The hottest months are usually July and June with an average temp of 70°F, while the coldest months are January and December with an average of 33°F. The snowiest months in La Mesilla are March, January, December, and February, with each month seeing an average of 9 inches of snowfall.