San Marco
Jacksonville
Popular places to visit
Mayo Clinic Florida
Though Mayo Clinic Florida might be what brings you to town, perhaps you'll have a chance to explore more of Jacksonville while you are here.
Jacksonville Naval Air Station
After visiting Jacksonville Naval Air Station, make a plan to see the other sights and activities in Jacksonville. Experience the great live music or attend a sporting event in this family-friendly area.
EverBank Stadium
Capable of seating over 80,000 fans, this modern football stadium is the exciting home of the Jacksonville Jaguars, international soccer games and music events.
TPC Sawgrass
Enjoy a round of golf in Ponte Vedra Beach at TPC Sawgrass. Stroll along the area's beautiful beaches or experience its acclaimed theater scene.
Jacksonville Zoo and Gardens
Admire thousands of animals and plants across entertaining exhibits in this family-friendly zoo that also has a children’s play area and a 4-D experience.
Prime F. Osborn III Convention Center
See exhibitions and join in community events at the former Union Station, a large train station which dates back to 1919.
Things to do
Jacksonville Residential Architecture & History Tour
The Escape Game at St. John's Town Center in Jacksonville
1 Hour Jet Ski Rental in Jacksonville, FL Evolution Jetsports
Electric Bike Tour with Free Application for Navigation
Top hotels in San Marco
Hilton Garden Inn Jacksonville Downtown Southbank
The room was clean.
Reviewed on Jan 5, 2026
Homewood Suites by Hilton Jacksonville Downtown-Southbank
Everything was wonderful!
Reviewed on Jan 10, 2026
Margaritaville Jacksonville Beach
The ocean view is exactly what I wanted. The bar had a great selection. The bartender, however was not attentive and didn't pay attention to how he made the drinks.
Reviewed on Jan 9, 2026
Hyatt Regency Jacksonville
Great
Reviewed on Jan 7, 2026
Embassy Suites by Hilton Jacksonville Baymeadows
Everything was great
Reviewed on Jan 10, 2026
DoubleTree by Hilton Hotel Jacksonville Riverfront
Great location on the river, not too loud, very nice scenery overall a nice place to stay
Reviewed on Jan 7, 2026
Other neighbourhoods around San Marco
Southbank
While you're in Southbank, take in top sights like Jacksonville Historical Center or Alexander Brest Planetarium, and hop on the metro to see more the city at Kings Avenue Station or Riverplace Station.
Downtown Jacksonville
Enjoy the stunning river views in Downtown Jacksonville. Florida Theatre is a worthwhile stop, and you can jump on the metro at Riverplace Station or Kings Avenue Station to see more of Jacksonville.
Riverside
Riverside is noteworthy for its restaurants, and you can make a stop at top attractions like Cummer Museum of Art and Gardens and 5 Points West Shopping Center.
Urban Core
While you're in Urban Core, take in top sights like Jacksonville Museum of Modern Art or Florida Theatre, and hop on the metro to see more the city at Rosa Parks Station or James Weldon Johnson Park Station.
Southside
If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.
Baymeadows
Check out the shopping, restaurants, and beaches while spending some time in Baymeadows. Though there might not be many attractions in the neighborhood, you won't need to go far to find top spots like Cinemark Tinseltown Jacksonville or St. Johns Town Center.
