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Guadalupe District Hotels near Santa Fe

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Our top choices for Guadalupe District hotels

Porch
Guadalupe Inn

Guadalupe Inn

Guadalupe Inn
2.0 star property
Guadalupe District
9.2 out of 10, Wonderful, (1000)
"Cozy, quiet, and great for couples!"
United States
Emerson
The price is P6,889
P8,113 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Guadalupe Inn
Terrace/patio
The Sage Hotel

The Sage Hotel

The Sage Hotel
3.0 star property
Don Diego, 0.6 km from Guadalupe District
8.0 out of 10, Very Good, (2141)
"Very friendly staff, beautifully clean rooms, great parking, and safe environment."
United States
Tavares
The price is P3,489
P4,900 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Sage Hotel
Meeting facility
Inn at Santa Fe, SureStay Collection by Best Western

Inn at Santa Fe, SureStay Collection by Best Western

Inn at Santa Fe, SureStay Collection by Best Western
3.0 star property
Southside, 11 km from Guadalupe District
8.6 out of 10, Excellent, (2085)
"Great customer service, clean rooms, and a great breakfast.⭐️⭐️⭐️⭐️ "
United States
Anna
The price is P4,176
P4,811 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Inn at Santa Fe, SureStay Collection by Best Western
Exterior
La Quinta Inn by Wyndham Santa Fe

La Quinta Inn by Wyndham Santa Fe

La Quinta Inn by Wyndham Santa Fe
3.0 star property
Southside, 8.3 km from Guadalupe District
7.0 out of 10, Good, (1605)
"Spacious parking and an excellent breakfast. Hotel is located in a prime area"
United States
Ramasamy
The price is P3,566
P4,107 total
includes taxes & fees
Jan 22 - Jan 23, 2026
La Quinta Inn by Wyndham Santa Fe
Exterior
El Sendero Inn, an Ascend Collection Hotel

El Sendero Inn, an Ascend Collection Hotel

El Sendero Inn, an Ascend Collection Hotel
2.5 star property
Downtown Santa Fe, 1.2 km from Guadalupe District
9.0 out of 10, Wonderful, (1539)
"Great stay. Will stay there again. "
United States
Mark
The price is P5,301
P6,106 total
includes taxes & fees
Jan 4 - Jan 5, 2026
El Sendero Inn, an Ascend Collection Hotel
Rooftop bar
Drury Plaza Hotel in Santa Fe

Drury Plaza Hotel in Santa Fe

Drury Plaza Hotel in Santa Fe
3.5 star property
Downtown Santa Fe, 1.4 km from Guadalupe District
9.6 out of 10, Exceptional, (1429)
"Very nice place to stay would recommend highly"
United States
Lisa Maxwell
The price is P8,736
P10,063 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Drury Plaza Hotel in Santa Fe
Desk, laptop workspace, blackout drapes, iron/ironing board
Coyote South

Coyote South

Coyote South
3.5 star property
Southside, 6.3 km from Guadalupe District
8.4 out of 10, Very Good, (3003)
"Great staff excellent accommodations "
United States
Randall
The price is P3,524
P4,647 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Coyote South
Outdoor pool, pool umbrellas, sun loungers
Hilton Vacation Club Villas de Santa Fe

Hilton Vacation Club Villas de Santa Fe

Hilton Vacation Club Villas de Santa Fe
3.0 star property
Northeast Santa Fe, 1 km from Guadalupe District
9.2 out of 10, Wonderful, (1007)
"It's a great place to stay! "
United States
Tonya
The price is P5,117
P5,894 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Hilton Vacation Club Villas de Santa Fe
View from room
Hilton Santa Fe Buffalo Thunder

Hilton Santa Fe Buffalo Thunder

Hilton Santa Fe Buffalo Thunder
4.0 star property
19.9 km from Guadalupe District
8.6 out of 10, Excellent, (1005)
"I love staying here, the golf and Casino, restaurants, spa are all amazing!"
United States
JESSICA
The price is P6,405
P7,321 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hilton Santa Fe Buffalo Thunder
Dining
Eldorado Hotel & Spa

Eldorado Hotel & Spa

Eldorado Hotel & Spa
4.0 star property
Downtown Santa Fe, 0.8 km from Guadalupe District
8.8 out of 10, Excellent, (1020)
"Great hotel in a great location. "
United States
stacy
The price is P6,436
P9,469 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Eldorado Hotel & Spa
Seasonal outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas
Hotel Glorieta

Hotel Glorieta

Hotel Glorieta
3.5 star property
1.6 km from Guadalupe District
8.2 out of 10, Very Good, (42)
"Loved the decor"
United States
Marian
The price is P5,233
P7,719 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hotel Glorieta
Lobby sitting area
Best Western Plus Inn of Santa Fe

Best Western Plus Inn of Santa Fe

Best Western Plus Inn of Santa Fe
2.5 star property
Southside, 6.9 km from Guadalupe District
8.8 out of 10, Excellent, (1001)
"Very adequate for 1 night stay."
United States
Tamsen
The price is P5,990
P6,900 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Best Western Plus Inn of Santa Fe
Exterior
Hotel Santa Fe

Hotel Santa Fe

Hotel Santa Fe
4.0 star property
Railyard Arts District, 0.5 km from Guadalupe District
9.2 out of 10, Wonderful, (1091)
"Lovely stay"
United States
Richard
The price is P7,876
P10,306 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Hotel Santa Fe
Front of property
Inn and Spa at Loretto

Inn and Spa at Loretto

Inn and Spa at Loretto
4.0 star property
Downtown Santa Fe, 1.1 km from Guadalupe District
9.0 out of 10, Wonderful, (1000)
"Yes … staff was excellent Outstanding"
United States
Charles
The price is P7,993
P11,432 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Inn and Spa at Loretto
Terrace/patio
Hampton Inn Santa Fe South

Hampton Inn Santa Fe South

Hampton Inn Santa Fe South
2.5 star property
Southside, 6.5 km from Guadalupe District
8.8 out of 10, Excellent, (761)
"Clean, comfortable rooms, and friendly staff:)"
United States
Christin
The price is P5,541
P6,382 total
includes taxes & fees
Jan 23 - Jan 24, 2026
Hampton Inn Santa Fe South
Lobby sitting area
Motel 6 Santa Fe, NM - Downtown

Motel 6 Santa Fe, NM - Downtown

Motel 6 Santa Fe, NM - Downtown
2.0 star property
Railyard Arts District, 0.5 km from Guadalupe District
7.8 out of 10, Good, (1003)
"Room was nice, easy check in."
United States
Alex
The price is P3,700
P4,262 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Motel 6 Santa Fe, NM - Downtown
Hypo-allergenic bedding, down comforters, desk, laptop workspace
Hyatt Place Santa Fe

Hyatt Place Santa Fe

Hyatt Place Santa Fe
3.0 star property
Southside, 8.5 km from Guadalupe District
8.8 out of 10, Excellent, (1001)
"The desk staff were very professional and polite"
United States
Nora
The price is P6,461
P7,442 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hyatt Place Santa Fe
Outdoor pool, a heated pool, sun loungers
Inn of the Governors

Inn of the Governors

Inn of the Governors
3.5 star property
Downtown Santa Fe, 0.9 km from Guadalupe District
9.6 out of 10, Exceptional, (1475)
"Incrediblen would one hundred percent stay again. Great location. Great food good prices great staff and clean!!"
United States
michael
The price is P8,751
P10,080 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Inn of the Governors
Seasonal outdoor pool
Hilton Santa Fe Historic Plaza

Hilton Santa Fe Historic Plaza

Hilton Santa Fe Historic Plaza
4.0 star property
Downtown Santa Fe, 0.8 km from Guadalupe District
8.2 out of 10, Very Good, (1004)
"Beautifully maintained- incredibly helpful staff and the perfect location to see the historic plaza and more. "
United States
Patricia
The price is P6,694
P7,711 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hilton Santa Fe Historic Plaza
Free buffet breakfast
Holiday Inn Express & Suites Santa Fe by IHG

Holiday Inn Express & Suites Santa Fe by IHG

Holiday Inn Express & Suites Santa Fe by IHG
2.5 star property
Southside, 6.3 km from Guadalupe District
9.0 out of 10, Wonderful, (859)
"Room was clean, the night staff was very friendly and helpful. "
United States
Trudy
The price is P5,991
P6,900 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express & Suites Santa Fe by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Guadalupe District

Find the best Guadalupe District areas and neighborhoods for the activities you enjoy most.

Downtown Santa Fe

Visitors to Downtown Santa Fe rave about its fascinating museums, popular shops, and acclaimed art galleries. You might also want to make some time to see Santuario De Nuestra Senora de Guadalupe or Lensic Performing Arts Center while you're exploring the neighborhood.

Southside

Southside is known for its popular shops, and with sights like Meow Wolf and Greer Garson Theater Center, you won't get bored spending a day wandering around this part of Santa Fe.

Canyon Road which includes interior views and art

Historic Eastside

While visiting Historic Eastside, you might make a stop by sights like Canyon Road and Edition ONE Gallery.

Tesuque

Tesuque is noteworthy for its spas, and you can make a stop at top attractions like Shidoni Foundry and Glenn Green Galleries & Sculpture Garden.

Northeast Santa Fe

If you're looking for some top things to see and do in Northeast Santa Fe and surrounding area, you can visit New Mexico Museum of Art and Cathedral Basilica of Saint Francis of Assisi.

Top Guadalupe District Hotel Reviews

Coyote South

Coyote South

10/10 Excellent
"The rooms were clean. Hotel staff were nice. Breakfast service was good. "
Jennifer 2-night trip
Posted 3 days ago
Coyote South

Frequently asked questions

What's it like in Guadalupe District?
You'll be sure to have fun visiting Santa Fe's Guadalupe District neighborhood. Be sure to check out Santa Fe Railyard and Santuario De Nuestra Senora de Guadalupe as part of your Guadalupe District travel plans.
What's the best accommodation in Guadalupe District?
Based on Expedia customer reviews, Guadalupe Inn is the highest ranked property in Guadalupe District. This hotel is a short 14-minute walk from Santa Fe Plaza, and it offers free breakfast and free WiFi.
How many hotels will I find in the Guadalupe District area?
If you're searching for places to stay in Santa Fe, Expedia has something to meet your needs with 65 Guadalupe District hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Guadalupe District, will I receive a refund?
Yes! The majority of room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to view the top deals on offer in Guadalupe District.
What can I see and do in this Santa Fe neighborhood?
Sights like El Museo Cultural, Art Vault, and TAI Modern can be part of your cultural tour of Guadalupe District. As you're discovering the neighborhood, Santa Fe Railyard and Santuario De Nuestra Senora de Guadalupe are some other places worth a visit. Santa Fe Farmers Market, SITE Santa Fe, and Harrell House of Natural Oddities and Bug Museum are just a few of the places to visit in and around Guadalupe District. While you're out sightseeing, Andrea Fisher Fine Pottery and Lensic Performing Arts Center are a couple of additional sights to visit in Santa Fe.
How can I get around Guadalupe District and the greater Santa Fe area?
If you want to head out of town, you can hop aboard a train at Santa Fe Depot.

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