Greater South Side Hotels near Des Moines

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Dec 26 - Dec 27
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Dec 27 - Dec 28
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

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Our top choices for Greater South Side hotels

Desk, iron/ironing board, free cribs/infant beds, rollaway beds
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport
2.0 star property
Greater South Side
8.6 out of 10, Excellent, (1687)
"Had a great stay and was impressed with the staff and the hotel. Will stay again!"
United States
Kevin
The price is P3,700
P4,144 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Days Inn & Suites by Wyndham Des Moines Airport
Free daily buffet breakfast
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport
2.5 star property
Greater South Side
7.4 out of 10, Good, (1002)
"Great staff very helpful. "
United States
Cleo and Michaelle
The price is P3,687
P4,130 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Quality Inn & Suites Des Moines Airport
Reception
AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport
2.5 star property
Greater South Side
7.8 out of 10, Good, (1003)
"The staff was great, check in was fast and easy"
United States
Joel
The price is P3,644
P4,082 total
includes taxes & fees
Jan 1 - Jan 2, 2026
AmericInn by Wyndham Des Moines Airport
Property amenity
Holiday Inn Des Moines-Airport/Conf Center by IHG

Holiday Inn Des Moines-Airport/Conf Center by IHG

Holiday Inn Des Moines-Airport/Conf Center by IHG
3.0 star property
Greater South Side
8.2 out of 10, Very Good, (597)
"Great staff, clean room "
United States
Kenny
The price is P6,813
P7,630 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Holiday Inn Des Moines-Airport/Conf Center by IHG
Free daily continental breakfast
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport
2.5 star property
Greater South Side
8.8 out of 10, Excellent, (1002)
"Friendly staff, clean room, comfy bed, and convenient shuttle."
United States
Cullanete
The price is P6,223
P6,969 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hampton Inn Des Moines-Airport
Free WiFi, bed sheets
Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA
2.0 star property
15.3 km from Greater South Side
7.8 out of 10, Good, (721)
"Nice clean room, friendly staff. "
United States
Cheryl
The price is P2,995
P3,354 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Motel 6 West Des Moines, IA
Free daily full breakfast
Holiday Inn Express Des Moines Ankeny by IHG

Holiday Inn Express Des Moines Ankeny by IHG

Holiday Inn Express Des Moines Ankeny by IHG
2.5 star property
17.5 km from Greater South Side
9.4 out of 10, Exceptional, (298)
"clean, friendly staff, room was well equipped"
United States
Colin
The price is P5,000
P5,600 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Holiday Inn Express Des Moines Ankeny by IHG
Exterior
Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG
3.0 star property
Historic East Village, 4.5 km from Greater South Side
9.4 out of 10, Exceptional, (1001)
"Staff was amazing. Room, pool, breakfast all spectacular. Enjoyed our stay. Will tell our friends and family and will come back "
United States
Amanda
The price is P4,581
P5,131 total
includes taxes & fees
Dec 29 - Dec 30
Staybridge Suites Des Moines Downtown by IHG
Indoor pool
La Quinta by Wyndham Altoona Des Moines

La Quinta by Wyndham Altoona Des Moines

La Quinta by Wyndham Altoona Des Moines
3.0 star property
17.4 km from Greater South Side
9.0 out of 10, Wonderful, (1530)
"Very nice staff member upon check in. Very nice hotel and well kept. "
United States
Debra
The price is P5,215
P5,841 total
includes taxes & fees
Jan 5 - Jan 6, 2026
La Quinta by Wyndham Altoona Des Moines
Lobby
Hampton Inn & Suites Altoona-Des Moines

Hampton Inn & Suites Altoona-Des Moines

Hampton Inn & Suites Altoona-Des Moines
2.5 star property
18.8 km from Greater South Side
9.2 out of 10, Wonderful, (672)
"Great place to stay!"
United States
Donald J
The price is P5,306
P5,943 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hampton Inn & Suites Altoona-Des Moines
Free daily buffet breakfast
Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines
3.0 star property
12.3 km from Greater South Side
9.4 out of 10, Exceptional, (1002)
"A great place to stay"
United States
Carol
The price is P5,873
P6,577 total
includes taxes & fees
Dec 28 - Dec 29
Drury Inn & Suites West Des Moines
Lobby
Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West
2.5 star property
14.9 km from Greater South Side
9.0 out of 10, Wonderful, (1000)
"Room was clean, staff was courteous and the bed was comfortable. "
United States
Craig
The price is P4,861
P5,445 total
includes taxes & fees
Dec 28 - Dec 29
Fairfield Inn and Suites by Marriott Des Moines West
Exterior
Courtyard Marriott Ankeny

Courtyard Marriott Ankeny

Courtyard Marriott Ankeny
3.0 star property
17.9 km from Greater South Side
8.8 out of 10, Excellent, (540)
"Location, easy check in, welcoming vibe. "
United States
Denise
The price is P4,942
P5,535 total
includes taxes & fees
Dec 29 - Dec 30
Courtyard Marriott Ankeny
Free daily buffet breakfast
Hotel Pommier Indianola

Hotel Pommier Indianola

Hotel Pommier Indianola
2.5 star property
20.9 km from Greater South Side
9.2 out of 10, Wonderful, (435)
"Loved it! Quaint and perfect stay! "
United States
Kara
The price is P4,117
P4,611 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hotel Pommier Indianola
Lobby
Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport
2.5 star property
Southwestern Hills, 6.2 km from Greater South Side
9.4 out of 10, Exceptional, (1167)
"Convenient location to restaurants"
United States
Sally
The price is P5,192
P5,815 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Baymont by Wyndham Des Moines Airport
In-room safe, desk, iron/ironing board, free WiFi
Econo Lodge Ankeny - Des Moines

Econo Lodge Ankeny - Des Moines

Econo Lodge Ankeny - Des Moines
2.0 star property
17.7 km from Greater South Side
8.2 out of 10, Very Good, (756)
"The room is quite comfortable Well maintained and clean "
United States
Dale
The price is P3,245
P3,634 total
includes taxes & fees
Dec 28 - Dec 29
Econo Lodge Ankeny - Des Moines
Lobby
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton
4.5 star property
Western Gateway, 3.7 km from Greater South Side
9.6 out of 10, Exceptional, (1066)
"Comfy and stylish lobby and rooms, delicious cafe"
United States
Sarah
The price is P8,380
P9,385 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Fort Des Moines, Curio Collection by Hilton
Property amenity
Staybridge Suites Des Moines North Ankeny by IHG

Staybridge Suites Des Moines North Ankeny by IHG

Staybridge Suites Des Moines North Ankeny by IHG
3.0 star property
17.5 km from Greater South Side
9.2 out of 10, Wonderful, (78)
"Great place to stay in DSM area!"
United States
Troy
The price is P6,450
P7,224 total
includes taxes & fees
Dec 27 - Dec 28
Staybridge Suites Des Moines North Ankeny by IHG
Free buffet breakfast
La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA
3.0 star property
18 km from Greater South Side
9.2 out of 10, Wonderful, (1000)
"Great stay with dogs"
United States
Mindy
The price is P4,607
P5,160 total
includes taxes & fees
Jan 1 - Jan 2, 2026
La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA
Indoor spa tub
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston
2.5 star property
14.3 km from Greater South Side
8.8 out of 10, Excellent, (1795)
"Traveled with my kids and they loved this place. "
United States
Erica
The price is P5,718
P6,404 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Stoney Creek Hotel Des Moines - Johnston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Greater South Side

Find the best Greater South Side areas and neighborhoods for the activities you enjoy most.
State Historical Society of Iowa Museum which includes a high rise building, landscape views and a city

Downtown Des Moines

The abundant dining options and live music are top of the list for many visitors to Downtown Des Moines. A stop by 801 Grand or Des Moines Civic Center might round out your trip.

Historic East Village

Historic East Village

Find beautiful government buildings, cultural attractions and a garden oasis in this older section of the city extending along a pretty riverfront.

Court District

Court District is known for its ample dining options, and you can make a stop by Science Center of Iowa and Principal Park while in the area.

Drake

If you're spending some time in Drake, Knapp Center and Des Moines Community Playhouse are top sights worth seeing.

Southwestern Hills

While Southwestern Hills might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Air Lanes Bowling Center and Gray’s Lake Park.

Top Greater South Side Hotel Reviews

Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

10/10 Excellent
"Great location and friendly check in"
Eric 1-night trip
Posted 3 days ago
Home2 Suites by Hilton Des Moines at Drake University

Frequently asked questions

What's it like in Greater South Side?
Travelers are sure to enjoy a stay in Des Moines's Greater South Side neighborhood. Consider a visit to Gray's Lake Park as part of your Greater South Side travel plans.
What's a favorite place to stay in Greater South Side?
Based on Expedia customer reviews, Days Inn & Suites by Wyndham Des Moines Airport is the highest ranked property in Greater South Side. This hotel offers free breakfast and an indoor pool. Other favorite options in the area include Hampton Inn Des Moines-Airport and AmericInn by Wyndham Des Moines Airport.
How many hotels will I be able to find in Greater South Side?
With 16 Expedia hotels and other accommodations in Greater South Side to choose from, this is a good starting point for exploring the greater Des Moines area.
If I need to cancel my hotel reservation in Greater South Side, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Add your dates and click on "Search", then use the "fully refundable" filter to get top deals in Greater South Side.
What is there to do around this Des Moines neighborhood?
Gray's Lake Park is an attraction you might want to check out while you're in Greater South Side. While you're out sightseeing, Air Lanes Bowling Center and Lauridsen Amphitheater are a couple of additional sights to visit in Des Moines.

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