Hotels near Florida Keys National Marine Sanctuary

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Florida Keys National Marine Sanctuary hotels

Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
10.0 out of 10, Exceptional, (1,000 reviews)
"Great location, great staff"
United States
Kurt Lee
The price is P18,436
P20,740 total
includes taxes & fees
Apr 29 - Apr 30
Almond Tree Inn Hotel - Adults Only

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,001 reviews)
"Enjoyed our stay, loved the location. Hotel and staff were friendly and accommodating."
United States
Mark
The price is P18,436
P20,740 total
includes taxes & fees
Apr 29 - Apr 30
Orchid Key Inn - Adults Only

Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
2.5 star property
Historic Seaport, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (939 reviews)
"Loved our stay here. The staff is so friendly and helpful. The property so quaint and well taken care of. Would recommend to anyone. We will be back for sure!! "
United States
Peter
The price is P14,515
P16,330 total
includes taxes & fees
Apr 28 - Apr 29
Simonton Court Historic Inn & Cottages

The Marquesa Hotel

The Marquesa Hotel
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,000 reviews)
"Great accommodations and great staff"
United States
Julian
The price is P21,718
P27,836 total
includes taxes & fees
May 10 - May 11
The Marquesa Hotel

Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (364 reviews)
"Great location near Duval Street but a couple blocks away so it much quieter than staying right on Duval. "
United States
Aaron
The price is P10,957
P13,559 total
includes taxes & fees
Apr 29 - Apr 30
Douglas House - Adults Only

H2O Suites - Adults Only

H2O Suites - Adults Only
3.5 star property
Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (599 reviews)
"This resort was in the perfect location for exploring Key West. Highly recommend!"
United States
Barton
The price is P27,876
P35,460 total
includes taxes & fees
May 11 - May 12
H2O Suites - Adults Only

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Historic Seaport, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (970 reviews)
"This was a lovely well stocked, and comfortable stay."
United States
Pat
The price is P11,844
P13,325 total
includes taxes & fees
Apr 28 - Apr 29
L'Habitation Guest House

Duval House

Duval House
3.0 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,022 reviews)
"Great place & location !!"
United States
Carl
The price is P13,301
P16,269 total
includes taxes & fees
May 3 - May 4
Duval House

Coco Plum Inn

Coco Plum Inn
3.0 star property
Downtown Key West, 0.6 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (519 reviews)
"Great location, pleasant staff & cute pool. "
United States
julie
The price is P16,598
P18,673 total
includes taxes & fees
Apr 26 - Apr 27
Coco Plum Inn

Island City House Hotel

Island City House Hotel
3.0 star property
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,002 reviews)
"A beautiful place to stay. Lovely room and very helpful staff. The gardens were beautiful."
United States
Margaret
The price is P16,501
P18,564 total
includes taxes & fees
May 10 - May 11
Island City House Hotel

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
3.5 star property
Old Town Key West, 1.7 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (142 reviews)
"Staff very courteous and friendly, public spaces lovely."
United States
Paul
The price is P11,424
P15,299 total
includes taxes & fees
Apr 26 - Apr 27
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Santa Maria Suites

Santa Maria Suites
4.0 star property
Uptown - Upper Duval, 1.3 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,000 reviews)
"The resort was so nice and perfect for our family of 5. We were in walking distance of restaurants and a small grocery store that has amazing breakfast. The lady that works the day shift ( I believe her name was Matilda) was so helpful and also helped us schedule a golf cart and an excursion making it super easy for us. We will be back to this resort for sure! "
United States
Terra
The price is P23,625
P30,678 total
includes taxes & fees
May 25 - May 26
Santa Maria Suites

Ambrosia Key West

Ambrosia Key West
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,001 reviews)
"Breakfast by the pool was excellent! Pools were nice, with plenty of areas for privacy. We especially enjoyed the private patios and courtyards. Fantastic location!"
United States
Tina
The price is P15,319
P17,234 total
includes taxes & fees
May 4 - May 5
Ambrosia Key West

Silver Palms Inn

Silver Palms Inn
3.5 star property
Old Town Key West, 1.3 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,026 reviews)
"The place was very clean and easy to get into. Parking was great. Breakfast was good. If I come back to the KEYS I will stay at Silver Palms Inn!!!!"
United States
Judy
The price is P10,331
P15,722 total
includes taxes & fees
Apr 26 - Apr 27
Silver Palms Inn

Ella's Cottages - Key West Historic Inns

Ella's Cottages - Key West Historic Inns
3.5 star property
Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (466 reviews)
"Amazing hotel, great staff, perfect location. 10/10 - we cant wait to come back for another visit and book there again!"
United States
Caitlin
The price is P24,232
P30,337 total
includes taxes & fees
May 26 - May 27
Ella's Cottages - Key West Historic Inns

Heron House - Adult Only

Heron House - Adult Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1,135 reviews)
"Love the Heron House, it s quaint and very comfortable, we absolutely love our stays there. "
United States
Burt
The price is P8,746
P11,907 total
includes taxes & fees
Apr 27 - Apr 28
Heron House - Adult Only

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
4.0 star property
Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1,085 reviews)
"Loved the location and the prximity to so many things we wanted to visit. The pool and services there were great!"
United States
Pamela
The price is P15,123
P19,405 total
includes taxes & fees
May 7 - May 8
Opal Key Resort & Marina, Key West

Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
4.0 star property
Uptown - Upper Duval, 1.2 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,005 reviews)
"Fresh continental breakfast, clean room, close to everything."
United States
BOBBY J.
The price is P16,343
P26,073 total
includes taxes & fees
Apr 30 - May 1
Southernmost House - Adult Exclusive

Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.2 out of 10, Wonderful, (1,001 reviews)
"Very convenient to many attractions walking distances Quiet staff very friendly and helpful "
United States
James
The price is P12,249
P16,513 total
includes taxes & fees
May 17 - May 18
Paradise Inn Key West - Adults Only

The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West, 1.6 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,001 reviews)
"This is a great place to stay, quiet and nice accommodations. Awesome little courtyard for breakfast."
United States
Jacqueline
The price is P13,464
P16,666 total
includes taxes & fees
Apr 26 - Apr 27
The Grand Guesthouse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Florida Keys National Marine Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds
Almond Tree Inn Hotel - Adults Only
3.5 star property
10.0
Exceptional
1,000 reviews
View
Property grounds
Orchid Key Inn - Adults Only
3.5 star property
9.8
Exceptional
1,001 reviews
View
Minibar, in-room safe, individually decorated, individually furnished
Simonton Court Historic Inn & Cottages
2.5 star property
9.8
Exceptional
939 reviews
View
Exterior
The Marquesa Hotel
3.5 star property
9.8
Exceptional
1,000 reviews
View
Exterior
Douglas House - Adults Only
3.0 star property
9.6
Exceptional
364 reviews
View

Top Florida Keys National Marine Sanctuary Hotel Reviews

Hotels near other Florida Keys National Marine Sanctuary attractions

Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?
Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, biking, and lively festivals. If you're looking for a convenient place to stay, check out the 1542 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Florida Keys National Marine Sanctuary?
Southernmost Beach Resort and Guesthouses is one of the top choices for your stay based on our traveler data, and this hotel offers 3 outdoor pools and a full-service spa. It's located just a short 0.7 mi (1.1 km) from Florida Keys National Marine Sanctuary. Other good choices close by include La Concha Key West, Autograph Collection and Pier House Resort & Spa.
How many hotels will I be able to find near Florida Keys National Marine Sanctuary?
Expedia has 1542 hotels and other accommodations within a mile from Florida Keys National Marine Sanctuary.
If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?
Yes, most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best options available near Florida Keys National Marine Sanctuary.
What can I see and do near Florida Keys National Marine Sanctuary?
Florida Keys Eco - Discovery Center, Harry S. Truman Little White House, and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum, and Audubon House and Tropical Gardens are some of the notable landmarks to see in the area. You can watch performances at Waterfront Playhouse, Key West Film Society, and Red Barn Theater if you're interested in local theater.