Default HTG hotel image

Hotels near Florida Keys National Marine Sanctuary

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Jun 26 - Jun 28
Next weekend
Jul 3 - Jul 5

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Florida Keys National Marine Sanctuary hotels

Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Downtown Key West, 0.9 km from Florida Keys National Marine Sanctuary
10.0 out of 10, Exceptional, (1,001 reviews)
"Excellent accommodations"
United States
Jimmy
The price is P9,482
P10,668 total
includes taxes & fees
Jun 29 - Jun 30
Almond Tree Inn Hotel - Adults Only
Exterior detail

The Gardens Hotel

The Gardens Hotel
4.0 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,000 reviews)
"Whole place is great"
United States
Joseph
The price is P12,096
P13,608 total
includes taxes & fees
Jun 23 - Jun 24
The Gardens Hotel
Property grounds

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Uptown - Upper Duval, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,004 reviews)
"Great boutique hotel in the perfect location !! "
United States
Michael
The price is P9,996
P11,246 total
includes taxes & fees
Jun 28 - Jun 29
Orchid Key Inn - Adults Only
Front of property

Key West Villas

Key West Villas
3.5 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (262 reviews)
"This was the best place we have stayed at in Key West! It was super quiet but only a block from Duval. The owners really put a lot of care into the place and are super nice! Definitely would stay there again! "
United States
Jennifer
The price is P12,528
P14,094 total
includes taxes & fees
Jun 29 - Jun 30
Key West Villas
Minibar, in-room safe, individually decorated, individually furnished

Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
2.5 star property
Historic Seaport, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (988 reviews)
"Perfcet location and walk to everything , we very much enjoyed our stay!"
United States
Rita
The price is P10,273
P11,557 total
includes taxes & fees
Jun 30 - Jul 1
Simonton Court Historic Inn & Cottages
Exterior

The Marquesa Hotel

The Marquesa Hotel
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (1,000 reviews)
"Friendly and helpful staff, and the rooms were exceptionally clean and comfortable. Everything was well-maintained, and the overall experience was wonderful. I will definitely be coming back again!"
United States
Helia
The price is P12,411
P17,381 total
includes taxes & fees
Jul 7 - Jul 8
The Marquesa Hotel
Exterior

Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Uptown - Upper Duval, 0.9 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (426 reviews)
"Great stay"
United States
Matthew
The price is P6,140
P7,598 total
includes taxes & fees
Jun 23 - Jun 24
Douglas House - Adults Only
Premium bedding, pillowtop beds, individually decorated

Tropical Inn

Tropical Inn
3.5 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (412 reviews)
"Very friendly staff and a prime location."
United States
Akhenaton
The price is P9,611
P12,333 total
includes taxes & fees
Jun 24 - Jun 25
Tropical Inn
Premium bedding, iron/ironing board, free WiFi, bed sheets

Weatherstation Inn

Weatherstation Inn
2.5 star property
Truman Annex, 0.6 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,002 reviews)
The price is P10,881
P12,241 total
includes taxes & fees
Jun 28 - Jun 29
Weatherstation Inn
Terrace/patio

The Conch House Heritage Inn

The Conch House Heritage Inn
3.5 star property
Old Town Key West, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (177 reviews)
"Great location "
United Kingdom
Lucy
The price is P14,443
P16,248 total
includes taxes & fees
Jun 24 - Jun 25
The Conch House Heritage Inn
View from room

H2O Suites - Adults Only

H2O Suites - Adults Only
3.5 star property
Uptown - Upper Duval, 1.1 km from Florida Keys National Marine Sanctuary
9.8 out of 10, Exceptional, (616 reviews)
"We had a wonderful stay!"
United States
Elizabeth
The price is P19,998
P26,601 total
includes taxes & fees
Jul 6 - Jul 7
H2O Suites - Adults Only
Exterior

Coco Plum Inn

Coco Plum Inn
3.0 star property
Downtown Key West, 0.6 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (537 reviews)
"Loved the property and staff was super friendly."
United States
Brinkley
The price is P10,914
P12,278 total
includes taxes & fees
Jul 13 - Jul 14
Coco Plum Inn
Property grounds

Duval House

Duval House
3.0 star property
Downtown Key West, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,038 reviews)
"Great location and clean rooms. Breakfast staff is so sweet! Will stay here again for sure!!"
United States
Wendy S
The price is P8,388
P10,744 total
includes taxes & fees
Jun 28 - Jun 29
Duval House
Front of property

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Historic Seaport, 0.8 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (995 reviews)
"Loved the location, breakfast and clean room. Staff, Drew, very friendly and helpful. Will definitely stay here again."
United States
Richard
The price is P7,604
P8,555 total
includes taxes & fees
Jun 28 - Jun 29
L'Habitation Guest House
Terrace/patio

Marrero's Guest Mansion

Marrero's Guest Mansion
3.5 star property
Downtown Key West, 0.7 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (337 reviews)
"It was nice. Get a smart tv 😂"
United States
Robert
The price is P12,096
P13,609 total
includes taxes & fees
Jun 29 - Jun 30
Marrero's Guest Mansion
Balcony view

Island City House Hotel

Island City House Hotel
3.0 star property
Historic Seaport, 1.2 km from Florida Keys National Marine Sanctuary
9.6 out of 10, Exceptional, (1,002 reviews)
"I love this Hotel. Great location, safe m, convenient. The staff is very accommodating."
United States
Paul
The price is P11,246
P12,652 total
includes taxes & fees
Jun 25 - Jun 26
Island City House Hotel
3 outdoor pools, a heated pool, sun loungers

Ambrosia Key West

Ambrosia Key West
3.5 star property
Old Town Key West, 1 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,000 reviews)
"Great location and breakfast"
United States
Lori
The price is P9,823
P11,051 total
includes taxes & fees
Jun 29 - Jun 30
Ambrosia Key West
Front of property

Caribbean House

Caribbean House
3.0 star property
Bahama Village, 0.5 km from Florida Keys National Marine Sanctuary
9.0 out of 10, Wonderful, (375 reviews)
"Had a wonderful stay"
Canada
Jeff
The price is P6,741
P9,103 total
includes taxes & fees
Jun 23 - Jun 24
Caribbean House
Outdoor pool, open 8:00 AM to 10:00 PM, sun loungers

Ella's Cottages - Key West Historic Inns

Ella's Cottages - Key West Historic Inns
3.5 star property
Old Town Key West, 0.9 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (483 reviews)
"Breakfast was delicious!! Fresh breads, fruit, meat and cheese, etc. Staff super friendly!!"
United States
Michelle
The price is P11,807
P16,361 total
includes taxes & fees
Jul 14 - Jul 15
Ella's Cottages - Key West Historic Inns
Exterior

Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
4.0 star property
Uptown - Upper Duval, 1.2 km from Florida Keys National Marine Sanctuary
9.4 out of 10, Exceptional, (1,003 reviews)
"Fresh continental breakfast, clean room, close to everything."
United States
BOBBY J.
The price is P9,677
P18,580 total
includes taxes & fees
Jul 6 - Jul 7
Southernmost House - Adult Exclusive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Florida Keys National Marine Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds
Almond Tree Inn Hotel - Adults Only
3.5 star property
10.0
Exceptional
1,001 reviews
View
Exterior detail
The Gardens Hotel
4.0 star property
9.8
Exceptional
1,000 reviews
View
Property grounds
Orchid Key Inn - Adults Only
3.5 star property
9.8
Exceptional
1,004 reviews
View
Front of property
Key West Villas
3.5 star property
9.8
Exceptional
262 reviews
View
Minibar, in-room safe, individually decorated, individually furnished
Simonton Court Historic Inn & Cottages
2.5 star property
9.8
Exceptional
988 reviews
View

Top Florida Keys National Marine Sanctuary Hotel Reviews

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

8/10 Good
"We enjoyed our stay at Le Mer. The room was clean, spacious and comfortable. The mattress was extra firm which was not to our liking. The private beach was not accessible and the grounds near the beach had a horrific smell."
Kimberley 3-night trip
Posted 10 hours ago
Southernmost Beach Resort and Guesthouses

Hotels near other Florida Keys National Marine Sanctuary attractions

Florida Keys Eco - Discovery Center

8.8/5 (128 reviews)
Learn about the area’s important marine ecology at this comprehensive attraction that addresses global environmental concerns, interesting for visitors of all ages.
See properties

Frequently asked questions

What's the area like around Florida Keys National Marine Sanctuary?
Florida Keys National Marine Sanctuary is located in an area of Key West known for its beautiful ocean views, biking, and lively festivals. If you're looking for a convenient place to stay, check out the 1542 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Florida Keys National Marine Sanctuary?
Adjacent to Florida Keys National Marine Sanctuary, Caribbean House is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and private balconies. Other good choices close by include Southernmost Beach Resort and Guesthouses and La Concha Key West, Autograph Collection.
How many hotels will I be able to find near Florida Keys National Marine Sanctuary?
Expedia has 1542 hotels and other accommodations within a mile from Florida Keys National Marine Sanctuary.
If I need to cancel the hotel reservation for my stay near Florida Keys National Marine Sanctuary, will I receive a refund?
Yes, most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best options available near Florida Keys National Marine Sanctuary.
What can I see and do near Florida Keys National Marine Sanctuary?
Florida Keys Eco - Discovery Center, Harry S. Truman Little White House, and Key West Lighthouse and Keeper's Quarters Museum feature captivating exhibits. Fort Zachary Taylor Historic State Park, Ernest Hemingway Home and Museum, and Audubon House and Tropical Gardens are some of the notable landmarks to see in the area. You can watch performances at Waterfront Playhouse, Key West Film Society, and Red Barn Theater if you're interested in local theater.