Business Hotels in South America

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Top Cities in South America

Bank of Brazil Cultural Center showing street scenes and heritage architecture as well as a large group of people
HotelsHotels

Sao Paulo

Sao Paulo

Check availability on South America Business Hotels

Tonight
Dec 29 - Dec 30
Tomorrow
Dec 30 - Dec 31
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for South America business-friendly hotels

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Radisson Blu Plaza El Bosque Santiago

Radisson Blu Plaza El Bosque Santiago

Radisson Blu Plaza El Bosque Santiago
4.0 star property
Las Condes
8.8 out of 10, Excellent, (1002)
"Very convenient location, excellent room and breakfast "
United States
VIVIAN
The price is P7,534
P7,534 total
Jan 1 - Jan 2, 2026
Radisson Blu Plaza El Bosque Santiago
Reception
Grand Hyatt Sao Paulo

Grand Hyatt Sao Paulo

Grand Hyatt Sao Paulo
5.0 star property
Itaim Bibi
9.4 out of 10, Exceptional, (1003)
"Rooms need update, very old "
United States
luiz felipe
The price is P11,106
P11,661 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Grand Hyatt Sao Paulo
Outdoor pool, free cabanas, pool umbrellas
Pullman Santiago Vitacura

Pullman Santiago Vitacura

Pullman Santiago Vitacura
5.0 star property
Vitacura
9.0 out of 10, Wonderful, (910)
"Great location and wonderful and accommodating staff. "
United States
Hillary
The price is P6,345
P6,345 total
Jan 16 - Jan 17, 2026
Pullman Santiago Vitacura
Outdoor pool, pool umbrellas, sun loungers
NH Collection Medellín Royal

NH Collection Medellín Royal

NH Collection Medellín Royal
5.0 star property
El Poblado
9.2 out of 10, Wonderful, (1004)
"excellent location, friendly staff, excellent food."
United States
Felix
The price is P6,735
P6,735 total
Jan 18 - Jan 19, 2026
NH Collection Medellín Royal
Free daily buffet breakfast
NM Lima Hotel

NM Lima Hotel

NM Lima Hotel
4.0 star property
San Isidro
9.2 out of 10, Wonderful, (1000)
"Excelent place, great food, nice people"
United States
Renato
The price is P4,569
P5,026 total
Dec 30 - Dec 31
NM Lima Hotel
Breakfast, lunch, dinner served; Peruvian cuisine
Pullman Lima San Isidro

Pullman Lima San Isidro

Pullman Lima San Isidro
4.0 star property
San Isidro
9.2 out of 10, Wonderful, (802)
"Everything was great about the hotel clean, the staff and amenities were all excellent."
United States
Nestor
The price is P5,525
P6,078 total
Jan 2 - Jan 3, 2026
Pullman Lima San Isidro
Reception
Hotel Plaza El Bosque Ebro

Hotel Plaza El Bosque Ebro

Hotel Plaza El Bosque Ebro
4.0 star property
Las Condes
9.0 out of 10, Wonderful, (1002)
"Simply a very pleasant hotel to stay at in a very nice area of town with plenty of great dining options nearby."
United States
Gerald
The price is P6,345
P6,932 total
Dec 30 - Dec 31
Hotel Plaza El Bosque Ebro
Outdoor treatment areas, sauna, hot tub, body treatments
Hotel Madero Buenos Aires, WorldHotels Elite

Hotel Madero Buenos Aires, WorldHotels Elite

Hotel Madero Buenos Aires, WorldHotels Elite
4.5 star property
Puerto Madero
9.2 out of 10, Wonderful, (1001)
"The staff is absolutely wonderful. Hotel is great too!"
United States
Anthony Miles
The price is P12,901
P13,077 total
Jan 4 - Jan 5, 2026
Hotel Madero Buenos Aires, WorldHotels Elite
Exterior
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

Regal Pacific Buenos Aires
4.5 star property
Microcentro
9.0 out of 10, Wonderful, (1003)
"The facility was very clean, conveniently located and the staff were very friendly and professional "
United States
Allan
Regal Pacific Buenos Aires
Lobby sitting area
GHL Hotel Capital

GHL Hotel Capital

GHL Hotel Capital
4.0 star property
Fontibon
9.2 out of 10, Wonderful, (1368)
"Ir was really grat staying in this hotel"
United States
Julio
The price is P4,718
P4,718 total
Jan 2 - Jan 3, 2026
GHL Hotel Capital
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South America Hotel Reviews

Melia Paulista

Melia Paulista

10/10 Excellent
"The best option and at a great value! Location and service were great."
Alisson L 3-night trip
Posted 2 days ago
Melia Paulista

Frequently asked questions

Why book your business-friendly hotel in South America with Expedia?
Here at Expedia, our top task is to help you choose the perfect stay at the right price. From luxurious, corporate-friendly getaways to affordable hotels filled with handy amenities, you'll have your next work trip organized in just a few clicks.
How can I find cheap business-friendly hotels in South America?
When work takes you to South America, our "business friendly" filter will help you find the right hotel. From fast WiFi to meeting rooms and workspaces, they have the amenities you need to do your job. You can also narrow your search by your budget and preferred star rating to view the cheapest properties.