Defiance Hotels

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Nov 17 - Nov 18
Tomorrow
Nov 18 - Nov 19
This weekend
Nov 21 - Nov 23
Next weekend
Nov 28 - Nov 30

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Top 10 trending Defiance hotels

Lobby sitting area
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
Fenton
8.0 out of 10, Very Good, (1008)
"Good hotel"
United States
Kelly
The price is P5,020
P5,797 total
includes taxes & fees
Nov 30 - Dec 1
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Ballroom
The Wildwood Hotel

The Wildwood Hotel

3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1600)
"Great hotel in a great neighborhood "
United States
Linda
The Wildwood Hotel
Property amenity
Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton

2.5 star property
Warrenton
7.4 out of 10, Good, (1003)
"The room was amazing the jacuzzi tub worked great we love our stay at Baymont "
United States
Christopher
The price is P5,049
P5,793 total
includes taxes & fees
Nov 23 - Nov 24
Baymont by Wyndham Warrenton
Front of property
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

3.0 star property
Chesterfield
8.0 out of 10, Very Good, (1021)
"This was a very nice place to stay. Centrally located, very clean and quiet with a great breakfast!"
United States
Kirsti
The price is P5,480
P6,356 total
includes taxes & fees
Nov 23 - Nov 24
Sonesta ES Suites St. Louis - Chesterfield
Lobby
Best Western Plus St. Louis West-Westport

Best Western Plus St. Louis West-Westport

2.5 star property
Maryland Heights
8.0 out of 10, Very Good, (1013)
"Clean rooms, courteous staff, good breakfast. Great stay at a reasonable price. "
United States
Shanna
The price is P5,846
P6,782 total
includes taxes & fees
Nov 18 - Nov 19
Best Western Plus St. Louis West-Westport
Exterior
Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG

2.5 star property
Wentzville
9.4 out of 10, Exceptional, (823)
"Comfortable beds good shower "
United States
Chad
The price is P6,968
P8,340 total
includes taxes & fees
Dec 12 - Dec 13
Holiday Inn Express & Suites Wentzville St Louis West by IHG
1 bedroom, Egyptian cotton sheets, premium bedding, pillowtop beds
Best Western Plus Washington Hotel

Best Western Plus Washington Hotel

2.5 star property
Washington
9.2 out of 10, Wonderful, (628)
"Great breakfast, comfortable room, and wonderful staff, all for a reasonable price. We stay here every time we are in Washington."
United States
Kimberly
The price is P7,618
P8,673 total
includes taxes & fees
Nov 19 - Nov 20
Best Western Plus Washington Hotel
Front of property
Super 8 by Wyndham Eureka/Six Flags Nearby

Super 8 by Wyndham Eureka/Six Flags Nearby

2.0 star property
Eureka
7.0 out of 10, Good, (1002)
"A much needed comfortable bed and hot shower, staff was lovely. "
United States
Rachel
The price is P3,543
P4,128 total
includes taxes & fees
Dec 7 - Dec 8
Super 8 by Wyndham Eureka/Six Flags Nearby
Exterior
Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG

2.5 star property
O'Fallon
8.6 out of 10, Excellent, (820)
"The staff was so friendly and helpful! The hotel was exceptionally clean. Breakfast was very good with lots of variety!"
United States
Millie
The price is P5,610
P6,617 total
includes taxes & fees
Nov 20 - Nov 21
Holiday Inn Express St. Louis West - O'Fallon by IHG
Lobby
Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive

2.5 star property
O'Fallon
8.8 out of 10, Excellent, (1007)
"Nice breakfast, friendly staff"
United States
Damon
The price is P5,209
P6,144 total
includes taxes & fees
Dec 5 - Dec 6
Sleep Inn & Suites O'Fallon MO - Technology Drive
Desk, blackout drapes, iron/ironing board, free cribs/infant beds
Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66

3.0 star property
Fenton
7.8 out of 10, Good, (1090)
"Yes Staff was awesome and respectful. "
United States
Anthony
The price is P4,668
P5,392 total
includes taxes & fees
Nov 30 - Dec 1
Wingate by Wyndham St. Louis/Fenton Route 66
Front of property - evening/night
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 star property
Maryland Heights
8.4 out of 10, Very Good, (2198)
"We had a pleasant stay."
United States
Larry
The price is P4,547
P6,156 total
includes taxes & fees
Dec 3 - Dec 4
Hollywood Casino & Hotel St. Louis
Lobby
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

3.0 star property
St. Charles
9.6 out of 10, Exceptional, (1004)
"Hotel was very clean."
United States
christine
The price is P6,791
P7,872 total
includes taxes & fees
Nov 23 - Nov 24
Drury Plaza Hotel St. Louis St. Charles
Lobby
Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles

2.0 star property
St. Peters
6.4 out of 10, (1000)
"Decent for the price"
United States
Kathie
The price is P3,966
P4,558 total
includes taxes & fees
Nov 23 - Nov 24
Days Inn by Wyndham St Peters/St Charles
In-room safe, desk, laptop workspace, blackout drapes
Super 8 by Wyndham Warrenton

Super 8 by Wyndham Warrenton

2.0 star property
Warrenton
7.4 out of 10, Good, (609)
"Ample free parking for our large RV. Staff was indifferent and acted like they were doing us a favor by letting us stay. Had to wait quite a while to be greeted for check in. Very limited lodging choices in the area, so??"
United States
Gary
The price is P3,614
P4,146 total
includes taxes & fees
Nov 25 - Nov 26
Super 8 by Wyndham Warrenton
Daily buffet breakfast (USD 12.95 per person)
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3.0 star property
Chesterfield
8.2 out of 10, Very Good, (780)
"Staff was courteous. "
United States
John
The price is P5,764
P6,707 total
includes taxes & fees
Nov 30 - Dec 1
Hilton Garden Inn Chesterfield
Exterior
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

2.5 star property
St. Charles
8.0 out of 10, Very Good, (1002)
"polite staff, great service, nice breakfast, clean room "
United States
John
The price is P5,528
P6,352 total
includes taxes & fees
Dec 14 - Dec 15
Hampton Inn St. Charles St. Peters
Lobby
AC Hotel by Marriott St. Louis Chesterfield

AC Hotel by Marriott St. Louis Chesterfield

3.5 star property
Chesterfield
9.2 out of 10, Wonderful, (226)
"Newer hotel, very clean, up to date and in nice area. "
United States
Johnny
The price is P7,028
P8,151 total
includes taxes & fees
Nov 23 - Nov 24
AC Hotel by Marriott St. Louis Chesterfield
In-room safe, laptop workspace, blackout drapes, iron/ironing board
Super 8 by Wyndham St. Clair MO

Super 8 by Wyndham St. Clair MO

2.0 star property
St. Clair
7.2 out of 10, Good, (933)
"Was what I needed after a long drive."
United States
Michael
The price is P3,933
P4,306 total
includes taxes & fees
Dec 9 - Dec 10
Super 8 by Wyndham St. Clair MO
Exterior
Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Holiday Inn Express & Suites St. Louis West - Fenton by IHG

3.0 star property
Fenton
8.8 out of 10, Excellent, (1001)
"Spotless room great mattress and pillows and super friendly staff"
United States
judith
The price is P6,968
P8,048 total
includes taxes & fees
Nov 23 - Nov 24
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Missouri wineries have some of the most superb wine we've ever tasted! We recommend sipping on some chambourcin while basking in the sunshine.
Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

This elegant Missouri winery showcases local and California wines from its hillside setting. Savor varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
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Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

August A. Busch Memorial Conservation Area

This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment.
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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

Top Defiance Hotel Reviews

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66

10/10 Excellent
"Everyone was so friendly!"
Natalie 1-night trip
Posted 4 days ago
Wingate by Wyndham St. Louis/Fenton Route 66

More cheap stays in Defiance

Relax Inn Saint Charles

Relax Inn Saint Charles

3800 Harry S Truman Blvd, St. Charles, MO
The price is P3,720 per night from Nov 18 to Nov 19
P3,720
P4,276 total
Nov 18 - Nov 19
includes taxes & fees
6.4/10 (999 reviews)

Frequently asked questions

What's the best place to stay in Defiance?
Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and Hilton St. Louis Frontenac. See all available top hotels, or vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodations with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Offers an indoor pool, an outdoor pool, and buffet. Hilton St. Louis Frontenac and La Quinta Inn & Suites by Wyndham St. Louis Westport are two additional hotels that offer an onsite pool. View all hotels with pools in Defiance.
What's it like to stay in Defiance?
Visitors can enjoy all that Defiance has to offer including the wineries and parks. Top sights in the area include St. Louis Union Station and Gateway Arch. In Defiance, there are 20 hotels and other accommodations to choose from. Find out more about Defiance.
What is there to see in Defiance?
Natural beauty is on display at Matson Hill Park Trailhead, August A. Busch Memorial Conservation Area, and Missouri River. A couple of additional sights to add to your agenda are Yellow Farmhouse Winery and Chandler Hill Vineyards. Check out what more to see and do in Expedia's Defiance guide.
What's the seasonal weather like in Defiance?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.

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