A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Defiance Hotels

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Sep 4 - Sep 5
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Sep 5 - Sep 6
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Sep 4 - Sep 6
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Sep 11 - Sep 13

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Our top choices for Defiance hotels

1. Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG
O'Fallon
United States
David
P5,939
P7,006 total
includes taxes & fees
Oct 4 - Oct 5
Holiday Inn Express St. Louis West - O'Fallon by IHG

2. The Wildwood Hotel

The Wildwood Hotel
Wildwood
United States
Hailey
P5,514
P6,423 total
includes taxes & fees
Sep 30 - Oct 1
The Wildwood Hotel

3. Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
O'Fallon
United States
Linda
P5,155
P6,080 total
includes taxes & fees
Sep 27 - Sep 28
Sleep Inn & Suites O'Fallon MO - Technology Drive

4. Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
Chesterfield
United States
Huda
P7,309
P8,477 total
includes taxes & fees
Sep 13 - Sep 14
Hyatt Place St. Louis/Chesterfield

5. Comfort Inn & Suites Chesterfield - St. Louis

Comfort Inn & Suites Chesterfield - St. Louis
Chesterfield
United States
Jessica
P5,224
P6,298 total
includes taxes & fees
Sep 13 - Sep 14
Comfort Inn & Suites Chesterfield - St. Louis

6. Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO
O'Fallon
United States
Kassie
P7,639
P9,058 total
includes taxes & fees
Sep 13 - Sep 14
Hilton Garden Inn St. Louis/O'Fallon MO

7. TownePlace Suites by Marriott St. Louis Chesterfield

TownePlace Suites by Marriott St. Louis Chesterfield
Chesterfield
United States
Bobbi jo
P8,003
P9,392 total
includes taxes & fees
Sep 13 - Sep 14
TownePlace Suites by Marriott St. Louis Chesterfield

8. Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield
Chesterfield
United States
Tenisha
P11,816
P13,824 total
includes taxes & fees
Sep 13 - Sep 14
Residence Inn by Marriott St. Louis Chesterfield

9. Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
Chesterfield
United States
Cassandra
P8,127
P9,426 total
includes taxes & fees
Sep 9 - Sep 10
Drury Plaza Hotel St. Louis Chesterfield

10. Staybridge Suites O'Fallon Chesterfield by IHG

Staybridge Suites O'Fallon Chesterfield by IHG
O'Fallon
United States
Norman
P6,940
P8,185 total
includes taxes & fees
Sep 7 - Sep 8
Staybridge Suites O'Fallon Chesterfield by IHG

11. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
Chesterfield
United States
NEBAHAT
P6,690
P7,784 total
includes taxes & fees
Oct 4 - Oct 5
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

12. Hampton Inn & Suites St. Louis/Chesterfield

Hampton Inn & Suites St. Louis/Chesterfield
Chesterfield
United States
Jodi
P6,870
P7,994 total
includes taxes & fees
Sep 13 - Sep 14
Hampton Inn & Suites St. Louis/Chesterfield

13. Quality Inn Foristell

Quality Inn Foristell
Foristell
United States
Chris
P5,233
P5,911 total
includes taxes & fees
Sep 10 - Sep 11
Quality Inn Foristell

14. Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
St. Peters
United States
Melanie
P6,877
P7,905 total
includes taxes & fees
Sep 13 - Sep 14
Drury Inn & Suites St. Louis St. Peters

15. Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
Washington
United States
Aaron
P8,065
P9,182 total
includes taxes & fees
Sep 6 - Sep 7
Best Western Plus Washington Hotel

16. Courtyard by Marriott St. Louis Chesterfield

Courtyard by Marriott St. Louis Chesterfield
Chesterfield
United States
Kelly
P7,259
P8,446 total
includes taxes & fees
Oct 4 - Oct 5
Courtyard by Marriott St. Louis Chesterfield

17. Comfort Inn Near Six Flags St. Louis

Comfort Inn Near Six Flags St. Louis
Pacific
United States
David
P6,189
P7,085 total
includes taxes & fees
Sep 21 - Sep 22
Comfort Inn Near Six Flags St. Louis

18. Hampton Inn St. Louis Wentzville

Hampton Inn St. Louis Wentzville
Wentzville
United States
Danielle
P8,664
P9,916 total
includes taxes & fees
Sep 13 - Sep 14
Hampton Inn St. Louis Wentzville

19. Fairfield Inn & Suites by Marriott St. Louis Chesterfield

Fairfield Inn & Suites by Marriott St. Louis Chesterfield
Chesterfield
United States
Thomas Kent
P6,696
P7,766 total
includes taxes & fees
Sep 13 - Sep 14
Fairfield Inn & Suites by Marriott St. Louis Chesterfield

20. Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield
Chesterfield
United States
Alvin
P6,806
P7,895 total
includes taxes & fees
Sep 13 - Sep 14
Sonesta ES Suites St. Louis - Chesterfield
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Stay near popular Defiance attractions

A wooden dock extending into a pond with lily pads, surrounded by lush greenery and a clear blue sky.

August A. Busch Memorial Conservation Area

8.6/10 (7 reviews)
This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment.
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A glass of red wine on a wooden table with a vineyard in the background.
Photo by Pages of Travel

Chandler Hill Vineyards

7.8/10 (7 reviews)
This elegant Missouri winery showcases local and California wines from its hillside setting. Savor varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
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Historic Daniel Boone Home and Heritage Center

9.6/10 (4 reviews)
Step into the limestone home where Daniel Boone's son Nathan crafted a frontier masterpiece with seven fireplaces. Explore the surrounding historic village for an authentic glimpse into 19th-century pioneer life.
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Sugar Creek Winery

8.0/10 (1 review)
Sip award-winning Missouri wines at this hillside vineyard along the scenic Katy Trail. Relax on covered decks with your own picnic while enjoying live weekend music and panoramic countryside views.
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Yellow Farmhouse Winery

This boutique winery in Defiance, Missouri was known for its distinctive unfiltered wines and relaxed atmosphere. Visitors could enjoy tastings with live music while picnicking on scenic grounds with vineyard views.
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Matson Hill Park Trailhead

Wander through 475 acres of rugged forest terrain with challenging hiking paths and gravity-flow mountain bike trails. The historic 1830s Hays Home offers a glimpse into pioneer life amid the natural splendor.
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Broemmelsiek Park

This 494-acre natural playground offers nine miles of trails through forests and around serene lakes. Attend a monthly stargazing event at the astronomy viewing area for a uniquely celestial park experience.
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Hamburg Trail Trailhead

This moderate 6.9-mile loop winds through the scenic Weldon Spring Conservation Area, connecting to the Katy Trail State Park. Spot native wildlife while traversing diverse landscapes of shaded woodlands and open fields.
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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Top Defiance Hotel Reviews

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

8/10 Good
"Checked into a room that the TV wasn't working...staff helpful to switch rooms. Pool was closed. :( Mattress a little soft for me. Breakfast was ok"
Nancy 1-night trip
Posted 15 hours ago
Comfort Suites St Charles - St Louis
Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive

10/10 Excellent
"The rooms were clean air conditioning was great staff were very friendly the breakfast was good"
Linda 3-night trip
Posted 16 hours ago
Sleep Inn & Suites O'Fallon MO - Technology Drive
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

10/10 Excellent
"We enjoyed our stay near the old city streets and shops. Our hotel was by far the best in the St. Louis/St. Charles area. We had a wonderful breakfast and a swim in the pool! The room was big with a great view."
Michael 1-night trip
Posted 1 day ago
Country Inn & Suites by Radisson, St. Charles Historic District
Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur

8/10 Good
"It was a nice stay. Much better than a motel 6 or some roadside motel. It was well kept and to standards."
Josef 1-night trip
Posted 2 days ago
Drury Plaza Hotel St. Louis Creve Coeur
Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

10/10 Excellent
"Quiet and restful room and convenient breakfast ."
Theresa 1-night trip
Posted 2 days ago
Drury Plaza Hotel St. Louis Chesterfield
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

10/10 Excellent
"We had a great stay. Nice and quiet."
Veronica 1-night trip
Posted 3 days ago
Sonesta ES Suites St. Louis - Chesterfield

More cheap stays in Defiance

Quality Inn Foristell

Quality Inn Foristell

12 Highway W Foristell MO
P5,233
P5,911 total
Sep 10 - Sep 11
includes taxes & fees
Quality Inn Foristell
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

1400 S 5th St St. Charles MO
P5,202
P5,978 total
Oct 4 - Oct 5
includes taxes & fees
8.4/10 Very Good! (1,009 reviews)
Comfort Suites St Charles - St Louis
Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive

1147 Technology Drive O'Fallon MO
P5,155
P6,080 total
Sep 27 - Sep 28
includes taxes & fees
9/10 Wonderful! (1,113 reviews)
Sleep Inn & Suites O'Fallon MO - Technology Drive
Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1310 Bass Pro Drive St. Charles MO
P5,626
P6,522 total
Sep 6 - Sep 7
includes taxes & fees
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

3720 W Clay St St. Charles MO
P6,026
P6,926 total
Sep 20 - Sep 21
includes taxes & fees
Hampton Inn St. Charles St. Peters
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

1190 S Main St St. Charles MO
P8,476
P9,742 total
Oct 4 - Oct 5
includes taxes & fees
9.4/10 Exceptional! (1,076 reviews)
Country Inn & Suites by Radisson, St. Charles Historic District

Find out more about Defiance

Top reasons to visit Defiance

  • Outdoor Adventures: Defiance is a haven for nature lovers, offering picturesque trails and hiking routes for exploration and relaxation.
  • Charming Downtown: Stroll through the quaint downtown area and absorb the local historical atmosphere.
  • Family-Friendly Activities: Enjoy a mix of urban parks and an amusement park, catering to all ages.
  • Romantic Getaways: Ideal for couples, Defiance provides serene spots perfect for romantic escapes.
  • Diverse Accommodation: A variety of lodging options are available, from pet-friendly hotels to family-oriented stays.

Find great hotels near Defiance

Discover a range of delightful accommodation options in Defiance, Missouri, perfect for every type of traveller. Whether you're seeking pet-friendly hotels, family-friendly stays, or business travel facilities, you'll find the ideal lodging to suit your needs. Explore the top hotels and available options in this charming area, ensuring a memorable visit to Defiance.

  • The Wildwood Hotel: Nestled in the heart of nature, The Wildwood Hotel offers a unique blend of adventure and comfort for those seeking an exhilarating getaway. Located 14.5km from Defiance, this 3.5-star hotel caters to outdoor enthusiasts with a range of adventure sports and recreational activities available onsite or nearby. From skiing and mountain climbing to hiking and biking, guests can immerse themselves in the stunning natural surroundings. The city centre location provides easy access to local attractions, making it an ideal choice for those wishing to explore both nature and urban experiences.
  • Drury Plaza Hotel St. Louis Chesterfield: Positioned 19.3km from Defiance, the Drury Plaza Hotel St. Louis Chesterfield is a welcoming haven for LGBTQIA travellers and their furry companions. This 3-star hotel is committed to inclusivity, featuring amenities that cater to both business and leisure guests. With pet-friendly policies allowing dogs and cats, along with a service animal fee waiver, visitors can enjoy a worry-free stay. The hotel is also well-equipped for business travellers, ensuring a comfortable and convenient experience for all.
  • Comfort Inn & Suites Chesterfield - St. Louis: Situated a mere 11.3km from Defiance, the Comfort Inn & Suites Chesterfield - St. Louis is the perfect choice for families and business travellers alike. This hotel provides a range of amenities tailored for children, including complimentary cribs, ensuring a comfortable stay for families. With its focus on both comfort and convenience, guests can expect a pleasant atmosphere that caters to their needs, making it an excellent base for exploring the local area.

Where to stay in and around Defiance

Defiance, Missouri, offers an enchanting blend of outdoor adventures and romantic escapes. Visitors can enjoy leisurely strolls through the charming downtown area, immersing themselves in the local historical vibe. Nearby cities and regions provide a family-friendly atmosphere, perfect for those seeking both relaxation and excitement. Whether you're indulging in entertainment or exploring the scenic beauty, Defiance promises an unforgettable getaway for every type of traveller.

  • Chesterfield: Located 19.3km from Defiance, Chesterfield is a vibrant city offering a delightful blend of family-friendly attractions and entertainment options. With a steady flow of visitors year-round, peak travel occurs in April and from June to July. The city boasts a variety of venues including theatres, an arcade adventure zone, and music concert locations. Not to be missed are the local landmarks such as the nearby theme park, sports facility stadium, and charming town neighbourhoods, making it a perfect destination for those seeking a lively city-themed experience.
  • Saint Albans: Just 6.4km from Defiance, Saint Albans is a picturesque city that attracts visitors with its outdoor and romantic experiences. Although visitor numbers fluctuate, peaks are noted in April, July, and September. This area is known for its amusement parks, arcade adventure zones, and recreational areas, appealing to families and couples alike. The city's highlights include a convention centre, an urban park, and a serene lake, providing a perfect backdrop for relaxation and adventure.
  • Hamburg: Nestled within the Defiance area, Hamburg is a quaint village that offers a charming escape for those seeking outdoor family activities and a city-themed experience. While its visitor numbers remain steady throughout the year, summer months from June to August see the highest influx of tourists. Attractions in Hamburg include parks, water features, and urban parks, making it an ideal spot for leisurely strolls and family outings amidst nature.

Things to do in and around Defiance

Defiance, Missouri, is an ideal destination for outdoor enthusiasts and couples seeking a romantic getaway. With access to picturesque trails and hiking routes, visitors can immerse themselves in nature while enjoying recreational areas perfect for relaxation. The charming location promises a memorable stay filled with delightful outdoor activities, making it a perfect choice for those wanting to explore the beauty of the great outdoors.

Shopping

The nearest shopping destination is St. Louis Premium Outlets, located 11.3km from Defiance, offering a variety of shops and family-friendly entertainment. If you're up for a drive, check out the Wentzville Flea Market, 20.9km away, for unique finds and local wares.

Recreation

Experience vibrant entertainment at The Factory music concert, only 16.1km from Defiance, perfect for unwinding with live performances. In Defiance itself, Broemmelsiek Park offers a serene environment for relaxation amidst nature, while Missouri Bluffs Golf Course, 11.3km away, invites you to enjoy outdoor sports in a picturesque setting.

Adventure

At Hidden Valley Ski Resort, located 14.5km from Defiance, enjoy exhilarating skiing on well-groomed slopes amidst stunning winter scenery. Explore Matson Hill Park Trailhead for a scenic hike, where outdoor adventure awaits. Additionally, Hurricane Harbor, 16.1km away, offers thrilling water slides and family-friendly entertainment for an unforgettable day.

Nightlife

For a lively evening, visit Chesterfield Sports Fusion, an arcade adventure zone offering family fun, just 14.5km from Defiance. Alternatively, enjoy a whimsical ride at St. Louis Carousel, 20.9km away, or immerse yourself in culture at the New Jewish Theatre, 32.2km away, perfect for a romantic night out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Defiance

For a budget-friendly visit to Defiance, plan your trip between December and February when accommodation prices are lower. Opt for a Monday stay, as it’s typically the cheapest day. Use Expedia to find affordable lodging by sorting prices and filtering for eco-certified hotels. Consider booking a package that combines flights, hotels, and activities for additional savings. Look out for flexible booking options and minute deals, and enjoy discounts on beverages at local establishments to enhance your experience without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Defiance are December to February, where the prices are slightly lower. This is in comparison to May to July, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Defiance is Monday. The most expensive day to stay in Defiance is Saturday.
  • Find cheap hotels on Expedia: Expedia's search tool enables you to specify your budget, preferred location, and additional criteria. You can arrange your search results to display prices from lowest to highest, ensuring you see the most affordable hotels first. Furthermore, you have the option to refine your selection by hotel type; for instance, by selecting the Eco-certified filter, you'll be presented with sustainable and environmentally friendly hotels ready for booking.
  • Consider bundling your trip: You can save money by combining your hotel booking in Defiance with your flights and activities through an Expedia package.

Find the best attractions near Defiance

Defiance offers a delightful mix of outdoor adventures and romantic experiences, perfect for family holidays. Visitors can explore urban parks and national state parks, while thrill-seekers can enjoy time at the local amusement park. The area caters to those seeking a blend of city life and nature, making it an ideal destination for a memorable getaway filled with entertainment and scenic beauty.

  • Chesterfield Central Park: Nestled 17.7km from Defiance, this park offers a serene escape with lush greenery and walking trails. Perfect for families, it promotes eco-friendly activities and outdoor fun, making it an ideal spot for picnics and leisurely strolls.
  • The Awakening Sculpture: Located 17.7km from Defiance, this impressive monument captures the imagination with its cultural significance. The sculpture's intricate design invites contemplation and provides a unique backdrop for photographs, celebrating artistic expression.
  • Six Flags St. Louis: Just 16.1km away, this amusement park promises a day of thrill and excitement. With roller coasters and family-friendly attractions, it's a perfect blend of adventure and outdoor enjoyment for visitors of all ages.

Best time to go to Defiance

The best time to visit Defiance is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly cloudy with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January31.6°F (-0.2°C)Light RainMostly CloudyModerately LowSlightly Low
February34.7°F (1.5°C)Light RainMostly SunnyAverageSlightly Low
March46.4°F (8.0°C)Light RainMostly SunnyAverageAverage
April55.9°F (13.3°C)Light RainMostly SunnyModerately HighAverage
May66.2°F (19.0°C)Light RainMostly SunnyAverageSlightly High
June75.9°F (24.4°C)Light RainMostly SunnyAverageSlightly High
July79.0°F (26.1°C)Light RainMostly SunnyModerately HighSlightly High
August77.2°F (25.1°C)Light RainMostly SunnyAverageAverage
September70.9°F (21.6°C)Light RainMostly SunnyModerately HighAverage
October58.5°F (14.7°C)Light RainMostly SunnyAverageAverage
November46.2°F (7.9°C)Light RainMostly SunnyModerately LowAverage
December37.6°F (3.1°C)Light RainMostly SunnyModerately LowSlightly Low

The nearest major airports for your trip to Defiance

Defiance, Missouri is conveniently accessible via two major airports. St. Louis Lambert International Airport (STL) is approximately 37.0km away, with excellent hotel options such as The Ritz-Carlton, St. Louis (11.3km from STL), and the Royal Sonesta Chase Park Plaza (14.5km from STL). Additionally, Spirit of St. Louis Airport (SUS) is located around 11.3km from Defiance, with nearby accommodations including the DoubleTree by Hilton Hotel St. Louis - Chesterfield (6.4km from SUS) and The Wildwood Hotel (9.7km from SUS). Both airports offer various transportation services, ensuring a smooth journey from your hotel to the airport.

Frequently asked questions

What's the best place to stay in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Hollywood Casino & Hotel St. Louis and Ameristar Casino Resort and Spa. See all available top hotels, or vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodations with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool, and buffet. Ameristar Casino Resort and Spa and The Wildwood Hotel are two additional hotels that offer an onsite pool. View all hotels with pools in Defiance.
What's it like to stay in Defiance?
Visitors can enjoy all that Defiance has to offer including the wineries and parks. Top sights in the area include St. Louis Union Station, Gateway Arch, and St. Louis Zoo. In Defiance, there are 19 hotels and other accommodations to choose from. Find out more about Defiance.
What is there to see in Defiance?
Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River, and Matson Hill Park Trailhead. A couple of additional sights to add to your agenda are Chandler Hill Vineyards and Sugar Creek Winery. Check out what more to see and do in Expedia's Defiance guide.
What's the seasonal weather like in Defiance?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.

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