A red train on tracks, palm trees, and modern buildings.

Hotels with Spa in Central San Diego, San Diego

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Check availability on Central San Diego Hotels with Spa

Next weekend
Nov 6 - Nov 8
In two weeks
Nov 13 - Nov 15

Our top choices for Central San Diego hotels with a spa

A hotel lobby with leather armchairs, a sofa, and a reception desk.

1. Hampton Inn San Diego-Kearny Mesa

Hampton Inn San Diego-Kearny Mesa
2.5 star property
Kearny Mesa
9.2 out of 10, Wonderful, (1,001 reviews)
"Fantastic hotel with very friendly staff"
United States
Jeffrey
The price is P7,314
P8,393 total
includes taxes & fees
Nov 15 - Nov 16
Hampton Inn San Diego-Kearny Mesa
A modern reception desk with a wooden panel backdrop and illuminated signage.

2. TownePlace Suites by Marriott San Diego Central

TownePlace Suites by Marriott San Diego Central
3.0 star property
Kearny Mesa
9.0 out of 10, Wonderful, (644 reviews)
"Great hotel all around!"
United States
Eduardo
The price is P10,839
P12,459 total
includes taxes & fees
Nov 20 - Nov 21
TownePlace Suites by Marriott San Diego Central
A modern bar area with wooden ceiling beams, bar stools, and a long counter.

3. Courtyard by Marriott San Diego Central

Courtyard by Marriott San Diego Central
3.0 star property
Kearny Mesa
8.8 out of 10, Excellent, (1,001 reviews)
"Great staff, clean rooms and excellent location"
United States
Ahmad
The price is P8,098
P9,308 total
includes taxes & fees
Nov 22 - Nov 23
Courtyard by Marriott San Diego Central
A spacious lobby with a high ceiling, modern furniture, and a fireplace.

4. Four Points by Sheraton San Diego

Four Points by Sheraton San Diego
3.5 star property
Kearny Mesa
8.2 out of 10, Very good, (1,002 reviews)
"Wonderful Weekend, hotel was nice and clean."
United States
Lucy
The price is P9,179
P10,550 total
includes taxes & fees
Nov 5 - Nov 6
Four Points by Sheraton San Diego
A modern hotel with a glass entrance, outdoor seating, and palm trees.

5. Hilton Garden Inn San Diego Mission Valley Stadium

Hilton Garden Inn San Diego Mission Valley Stadium
3.0 star property
Kearny Mesa
8.0 out of 10, Very good, (1,007 reviews)
"Overall, our stay was great!"
United States
Willy
The price is P7,531
P8,656 total
includes taxes & fees
Nov 8 - Nov 9
Hilton Garden Inn San Diego Mission Valley Stadium
Room

6. Extended Stay America Suites San Diego Mission Valley Stadium

Extended Stay America Suites San Diego Mission Valley Stadium
2.5 star property
Kearny Mesa
6.6 out of 10, (1,001 reviews)
"Room was clean, staff was great and its in a convenient location."
United States
Brenda
The price is P7,083
P8,142 total
includes taxes & fees
Dec 1 - Dec 2
Extended Stay America Suites San Diego Mission Valley Stadium
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

7. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (236 reviews)
"Friendly staff!"
United States
Donavin
The price is P7,387
P10,497 total
includes taxes & fees
Nov 4 - Nov 5
City24 Hotel Little Italy Mission Hills
A hotel entrance with a stone archway, a reception desk, and potted plants.

8. Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
Mission Hills
9.2 out of 10, Wonderful, (1,096 reviews)
"Love the hotel, the breakfast was good and the staff was exceptional."
United States
Patricia
The price is P8,669
P9,964 total
includes taxes & fees
Nov 8 - Nov 9
Holiday Inn Express San Diego Airport - Old Town by IHG
An outdoor patio with wicker furniture, a stone fire pit, and blue umbrellas.

9. HYATT house San Diego/Sorrento Mesa

HYATT house San Diego/Sorrento Mesa
3.0 star property
Sorrento Valley
9.2 out of 10, Wonderful, (1,001 reviews)
"Overall great location, staff, and room"
United States
Melissa
The price is P10,836
P12,455 total
includes taxes & fees
Nov 15 - Nov 16
HYATT house San Diego/Sorrento Mesa
An outdoor seating area with a fire feature, white chairs, and potted plants.

10. Springhill Suites San Diego Mission Valley

Springhill Suites San Diego Mission Valley
3.5 star property
Mission Valley
9.2 out of 10, Wonderful, (1,001 reviews)
"Kind receiption, very well-managed hotel, and nice location."
South Korea
Jin Soo
The price is P10,269
P11,803 total
includes taxes & fees
Nov 22 - Nov 23
Springhill Suites San Diego Mission Valley
A modern bathroom with a shower, a towel rack, and a bench.

11. Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (3,101 reviews)
"We really enjoyed our stay. The pool was great and really enjoyed the bar and staff"
United States
Kathy
The price is P9,816
P11,283 total
includes taxes & fees
Nov 22 - Nov 23
Legacy Resort Hotel & Spa
A bar area with a glass ceiling, a central bar counter, and multiple stools.

12. Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
University Heights
9.4 out of 10, Exceptional, (2,126 reviews)
"Beautiful hotel with wonderful staff! I have already booked my next stay. I would highly recommend this hotel."
United States
Heather
The price is P17,401
P20,002 total
includes taxes & fees
Nov 2 - Nov 3
Lafayette Hotel & Club
A living room with a sectional sofa, a wooden coffee table, a blue ottoman, a wooden chair with cushions, a built-in bookshelf, and a stone wall with a fireplace.

13. Country Inn & Suites by Radisson, San Diego North, CA

Country Inn & Suites by Radisson, San Diego North, CA
3.0 star property
Sorrento Valley
9.0 out of 10, Wonderful, (1,740 reviews)
"Had a great stay!"
United States
Terrance
The price is P8,614
P9,902 total
includes taxes & fees
Nov 22 - Nov 23
Country Inn & Suites by Radisson, San Diego North, CA
An outdoor seating area with a pergola, tables, and chairs, and a sign welcoming to the Cosmopolitan Restaurant.

14. Cosmopolitan Hotel & Restaurant

Cosmopolitan Hotel & Restaurant
2.5 star property
Old Town San Diego
9.2 out of 10, Wonderful, (771 reviews)
"Great atmosphere! Perfect place to enjoy all of Old town San Diego"
United States
Alan
The price is P11,865
P13,378 total
includes taxes & fees
Nov 3 - Nov 4
Cosmopolitan Hotel & Restaurant
An outdoor patio with a fire feature, seating, and string lights.

15. Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
4.0 star property
University City
8.8 out of 10, Excellent, (2,116 reviews)
"Nice a friendly staff! Great hotel in beautiful La Jolla!"
United States
Tristan
The price is P10,383
P13,751 total
includes taxes & fees
Nov 22 - Nov 23
Embassy Suites by Hilton San Diego La Jolla
A spacious lobby with a central seating area, a reception desk, and a staircase leading to an upper level.

16. Courtyard by Marriott San Diego Miramar

Courtyard by Marriott San Diego Miramar
3.0 star property
Miramar
8.8 out of 10, Excellent, (1,001 reviews)
"Decent Hotel"
United States
Jignesh
The price is P10,782
P12,393 total
includes taxes & fees
Nov 14 - Nov 15
Courtyard by Marriott San Diego Miramar
A hotel reception area with a receptionist, wooden reception desks, and a large wall art installation.

17. Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area
3.0 star property
Mission Valley
8.8 out of 10, Excellent, (1,746 reviews)
"Clean room, very friendly staff, great breakfast."
United States
Edith
The price is P8,344
P9,591 total
includes taxes & fees
Nov 16 - Nov 17
Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area
A patio area with a circular fire pit surrounded by wicker furniture and a stone wall.

18. Courtyard by Marriott San Diego Sorrento Valley

Courtyard by Marriott San Diego Sorrento Valley
3.0 star property
Sorrento Valley
8.8 out of 10, Excellent, (1,000 reviews)
"Nice hotel."
United States
KATHERINE
The price is P9,695
P11,160 total
includes taxes & fees
Nov 20 - Nov 21
Courtyard by Marriott San Diego Sorrento Valley
A modern bathroom with a glass shower enclosure, a toilet, and a vanity with a large mirror.

19. Holiday Inn Express Hotel & Suites San Diego-Sorrento Valley by IHG

Holiday Inn Express Hotel & Suites San Diego-Sorrento Valley by IHG
2.5 star property
Sorrento Valley
8.8 out of 10, Excellent, (1,001 reviews)
"Solid place to stay"
United States
Johnathan
The price is P8,344
P9,591 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express Hotel & Suites San Diego-Sorrento Valley by IHG
A hotel with a central courtyard, palm trees, and a fountain.

20. Hilton Garden Inn San Diego Old Town/SeaWorld Area

Hilton Garden Inn San Diego Old Town/SeaWorld Area
3.0 star property
Old Town San Diego
8.8 out of 10, Excellent, (1,553 reviews)
"Nice hotel, close to everything."
United States
Sheri
The price is P7,910
P9,092 total
includes taxes & fees
Nov 30 - Dec 1
Hilton Garden Inn San Diego Old Town/SeaWorld Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Central San Diego

Pool
Breakfast included

Top Central San Diego Hotel Reviews

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG

10/10 Excellent
"I recently stayed here on a one night trip to San Diego to see a friend. The property is massive, very well maintained by staff. From check-in to check-out, things ran smoothly, the room was big and comfortable and clean. Fair warning the property is massive so it was a bit of a maze to try to find my room when I first arrived. They have a beautiful courtyard along with an amazing swimming pool right smack in the middle of the hotel which was beautiful. Few minor little things that I think the hotel could look at to improve it and make it that much better would be: The shower in my room was not very hot during my stay which was kind of weird, it was lukewarm at best. Secondly, I had notified Front desk and they approved a late check out for me, however house keeping the morning of departure decided to knock twice in under a hour even after I told the front desk and got approval for the late checkout. So maybe better communication between the front desk and the housekeeping staff. Overall though I would recommend this property, just be aware they do charge for overnight parking, which I have mixed feelings about. They should implement a visitor parking so that people who are just here to visit can park free of charge. It is $5 USD per hour."
Colin 1-night trip
Posted less than an hour ago
Crowne Plaza San Diego - Mission Valley by IHG