A red train on tracks, palm trees, and modern buildings.

Central San Diego hotel rooms a the Motel 6

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Sep 9 - Sep 10
Tomorrow
Sep 10 - Sep 11
This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

Our top choices for Central San Diego Motel 6

1. Motel 6 San Diego, CA - Hotel Circle - Mission Valley

Motel 6 San Diego, CA - Hotel Circle - Mission Valley
Mission Valley
United States
Jack
P4,895
P5,629 total
includes taxes & fees
Oct 11 - Oct 12
Motel 6 San Diego, CA - Hotel Circle - Mission Valley

2. Motel 6 San Diego, CA - North

Motel 6 San Diego, CA - North
Clairemont
United States
Rony
P5,829
P6,582 total
includes taxes & fees
Sep 23 - Sep 24
Motel 6 San Diego, CA - North
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top Central San Diego Hotel Reviews

Lafayette Hotel & Club

Lafayette Hotel & Club

10/10 Excellent
"Very memorable, loved the diner"
DANIEL 1-night trip
Posted 2 hours ago
Lafayette Hotel & Club
Handlery Hotel

Handlery Hotel

10/10 Excellent
"I’ve disliked quite a few hotels around this area of SD, but this was my first overwhelmingly positive experience at a hotel in SD!! Everything was perfect; the staff, the room, the amenities, and location were all amazing! I will definitely be coming back next time :)"
Sophia 1-night trip
Posted 3 hours ago
Handlery Hotel
Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG

10/10 Excellent
"The exterior of the buildings look dated. New paint with contemporary color scheme would be really helpful. The room itself was exceptional. Comfortable bed, ample pillows, plenty of options on TV. I don't mind a bathtub/shower combo but maybe they could renovate over to a shower only. Front desk was cheerful, helpful and informative. Breakfast wait staff was great!!!! Buffet price $22 was more than fair. There did not seem to be a lot of guests. The restaurant was closed in the evening so I ate in the bar. Limited menu but my chicken flatbread was really good. I chose this property for the reasonable price point and proximity to Fashion Valley Mall which is my happy shopping place. I would definitely stay there again."
Carol 1-night trip
Posted 4 hours ago
Crowne Plaza San Diego - Mission Valley by IHG
Country Inn & Suites by Radisson, San Diego North, CA

Country Inn & Suites by Radisson, San Diego North, CA

10/10 Excellent
"Clean room and friendly staff"
Karthik 3-night trip
Posted 6 hours ago
Country Inn & Suites by Radisson, San Diego North, CA
Kings Inn San Diego

Kings Inn San Diego

10/10 Excellent
"You know I was staying in San Diego again, this time with my girlfriend. We had the king suite which was inside the building above the lobby. Really liked the room a lot very spacious, but it was a great place to hang my hat at night. It was close to old town. It was close to Seaworld and that’s pretty much what I was doing this weekend. The staff is amazing. They were really cool on Wednesday when I was there to spend the night to see Guns N’ Roses, and they agreed again for the just chill holiday weekend."
Michael 2-night trip
Posted 20 hours ago
Kings Inn San Diego

Explore a world of travel with Expedia