Hotels near Casa Santo Domingo

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 21 - Dec 22
Tomorrow
Dec 22 - Dec 23
Next weekend
Dec 26 - Dec 28
In two weeks
Jan 2 - Jan 4

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Casa Santo Domingo hotels

Frette Italian sheets, hypo-allergenic bedding, down comforters
Royal Isabela

Royal Isabela

Royal Isabela
4.5 star property
16 km from Casa Santo Domingo
9.6 out of 10, Exceptional, (163)
"Great resort! "
United States
Jodie
The price is P41,047
P53,689 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Royal Isabela
Beach
Colinas del Atlantico for 18 People

Colinas del Atlantico for 18 People

Colinas del Atlantico for 18 People
3.5 star property
15.7 km from Casa Santo Domingo
9.4 out of 10, Exceptional, (12)
"This property was spacious and great for our family of 14"
United States
Maria
The price is P11,627
P23,094 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Colinas del Atlantico for 18 People
Living area
El Oasis Hotel

El Oasis Hotel

El Oasis Hotel
3.5 star property
17.1 km from Casa Santo Domingo
9.4 out of 10, Exceptional, (116)
"My family and I stay at the "
United States
Joseph
The price is P4,797
P5,229 total
includes taxes & fees
Dec 22 - Dec 23
El Oasis Hotel
Beach
Colinas del Atlantico Vacational House 1st Floor

Colinas del Atlantico Vacational House 1st Floor

Colinas del Atlantico Vacational House 1st Floor
3.5 star property
15.7 km from Casa Santo Domingo
9.0 out of 10, Wonderful, (35)
"Very comfortable apartment (1st floor) will definitely rent again."
United States
Abimael
Colinas del Atlantico Vacational House 1st Floor
Down comforters, memory foam beds, in-room safe, individually decorated
Luxury Puerto Caribe Boutique Hotel

Luxury Puerto Caribe Boutique Hotel

Luxury Puerto Caribe Boutique Hotel
3.5 star property
18.5 km from Casa Santo Domingo
9.4 out of 10, Exceptional, (77)
"Love this place, the service, great room, the staff was amazing helpful and accommodating. "
United States
Janice
Luxury Puerto Caribe Boutique Hotel
Exterior
Golden Dream Villas 306 A

Golden Dream Villas 306 A

Golden Dream Villas 306 A
3.5 star property
17.8 km from Casa Santo Domingo
9.2 out of 10, Wonderful, (40)
"Very nice spot and condo"
United States
Nicholas
The price is P4,965
P12,756 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Golden Dream Villas 306 A
Porch
Hacienda Juanita

Hacienda Juanita

Hacienda Juanita
3.0 star property
18.2 km from Casa Santo Domingo
8.8 out of 10, Excellent, (523)
"Nice"
Canada
Keith
Hacienda Juanita
2 outdoor pools
Hotel Vista Azul

Hotel Vista Azul

Hotel Vista Azul
3.0 star property
19.8 km from Casa Santo Domingo
9.0 out of 10, Wonderful, (17)
"Great property. Had lots to do. Only issue is parking as the club and other activities people park so hard for guests to park"
United States
Rose M
The price is P7,340
P8,293 total
includes taxes & fees
Dec 22 - Dec 23
Hotel Vista Azul
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers
Hotel El Guajataca

Hotel El Guajataca

Hotel El Guajataca
3.5 star property
17 km from Casa Santo Domingo
8.4 out of 10, Very Good, (1004)
"Wonderful sea view from every room. Nice personnel Excelent complementary breakfast The best view in the whole area Single deluxe room includes microwave and minifridge"
United States
Iris
Hotel El Guajataca
Property amenity
Golden Dream Studio 306 B

Golden Dream Studio 306 B

Golden Dream Studio 306 B
3.0 star property
17.8 km from Casa Santo Domingo
8.6 out of 10, Excellent, (24)
"This place was terrible, very unclean and bugs in the walls. Reached out to all numbers provided (phone, WhatsApp etc) to report the conditions of the place and did not receive a response. I do not recommend this place at all … terrible terrible unsanitary experience. The female security was the only good experience, she was very kind and respectful. "
United States
Alicia
The price is P4,439
P11,100 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Golden Dream Studio 306 B
Outdoor pool
Sea Breeze Tunnel Hideaway 6

Sea Breeze Tunnel Hideaway 6

Sea Breeze Tunnel Hideaway 6
3.5 star property
17.6 km from Casa Santo Domingo
8.4 out of 10, Very Good, (6)
"Spectacular part of the island. Great location."
United States
Donna
The price is P6,659
P14,299 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Sea Breeze Tunnel Hideaway 6
Beach nearby, beach shuttle, sun loungers, beach umbrellas
Medusas Hostel

Medusas Hostel

Medusas Hostel
3.0 star property
18.5 km from Casa Santo Domingo
7.6 out of 10, Good, (98)
"Poor location, noisy, run-down lodging area."
United States
ALEXIS
The price is P4,228
P5,489 total
includes taxes & fees
Dec 22 - Dec 23
Medusas Hostel
On the beach
Jobos Beach Apartment A-3

Jobos Beach Apartment A-3

Jobos Beach Apartment A-3
3.0 star property
18.7 km from Casa Santo Domingo
7.4 out of 10, Good, (20)
"Excellent location"
United States
Alberto
The price is P3,911
P11,169 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Jobos Beach Apartment A-3
Private kitchen
Jobos Luxury Condos

Jobos Luxury Condos

Jobos Luxury Condos
2.5 star property
18.7 km from Casa Santo Domingo
4.8 out of 10, (46)
"Loved it "
United States
Ingry N
The price is P7,399
P7,917 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Jobos Luxury Condos
Rooftop terrace
Ache Pa Ti 1

Ache Pa Ti 1

Ache Pa Ti 1
3.5 star property
18.1 km from Casa Santo Domingo
The price is P4,756
P13,505 total
includes taxes & fees
Dec 22 - Dec 23
Ache Pa Ti 1
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Casa Santo Domingo Hotel Reviews

Hotel El Guajataca

Hotel El Guajataca

10/10 Excellent
"Goodddddd"
Jose 3-night trip
Posted 7 days ago
Hotel El Guajataca
Hotel Villas del Rey

Hotel Villas del Rey

8/10 Good
"The property were exactly what we expected, Carmen and crew were very nice, I really recommend this property, enjoyed."
Alvaro Rene Castillo 5-night trip
Posted 11 months ago
Hotel Villas del Rey

Hotels near other Casa Santo Domingo attractions

Guajataca State Forest

Commune with nature and explore the great outdoors at Guajataca State Forest during your travels in Isabela. Stroll along the beautiful beaches in this romantic area, or check out its top-notch restaurants.
See properties

Aventuras Borinken

Commune with nature and explore the great outdoors at Aventuras Borinken during your travels in San Sebastian. Wander the beaches and seaside in this relaxing area.
See properties

Frequently asked questions

What's the area like around Casa Santo Domingo?
Casa Santo Domingo is located in an area of Guatemala that travelers like for its beaches. If you're looking for a convenient place to stay, check out the 5 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Casa Santo Domingo?
Hotel Villas del Rey is one of the top choices for your stay based on our traveler data, and this hotel offers 15 outdoor pools and 2 restaurants. It's located just a short 0.4 mi (0.7 km) from Casa Santo Domingo. Other good options close by include Villas del Rey Hotel and San Sebastian Bed & Breakfast.
How many hotels should I expect to find close to Casa Santo Domingo?
Expedia has 5 hotels and other accommodations within a mile from Casa Santo Domingo.
If I need to cancel the hotel reservation for my stay near Casa Santo Domingo, will I receive a refund?
Yes! Most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the best deals available near Casa Santo Domingo.