Photo by Alice Burghart

Cape Girardeau Hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Cape Girardeau hotels

Quality Inn

2.5 star property
7.0 out of 10, Good, (626)
"Staff was wonderful and helpful pool was great room was comfortable breakfast needs improvements decent for what they had "
The price is P3,514
P3,964 total
includes taxes & fees
Sep 7 - Sep 8
Quality Inn

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1002)
"Excellent place to stay "
The price is P3,995
P4,507 total
includes taxes & fees
Aug 21 - Aug 22
Pear Tree Inn Cape Girardeau Near the Medical Center

Town House Inn

2.5 star property
7.6 out of 10, Good, (405)
"The housekeepers steal and the owners help them and allow it I’m not changing me review Expedia it’s the truth "
The price is P3,339
P3,614 total
includes taxes & fees
Aug 18 - Aug 19
Town House Inn

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (390)
"Nice place to stay! everything was fun and clean."
The price is P6,010
P6,780 total
includes taxes & fees
Aug 19 - Aug 20
The Riverview

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very Good, (728)
"Great area, fast check in, quiet, very spacious"
The price is P5,080
P5,498 total
includes taxes & fees
Aug 20 - Aug 21
Comfort Suites Jackson-Cape Girardeau

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1002)
"We had a last minute reservation here. The staff was very pleasant, helpful and wonderful overall!!"
The price is P5,136
P5,430 total
includes taxes & fees
Aug 24 - Aug 25
Drury Inn & Suites Jackson MO

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (981)
"Easy access and parking"
The price is P5,136
P5,794 total
includes taxes & fees
Aug 22 - Aug 23
Drury Inn & Suites Cape Girardeau

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (738)
"Nice and clean hotel friendly service"
The price is P6,258
P7,060 total
includes taxes & fees
Aug 24 - Aug 25
Hampton Inn Cape Girardeau I 55 East

Town House Inn Cape Giradreau

2.5 star property
6.0 out of 10, (194)
"Easy to get in and out "
The price is P3,995
P4,667 total
includes taxes & fees
Aug 18 - Aug 19
Town House Inn Cape Giradreau

Tru By Hilton Cape Girardeau

2.5 star property
9.6 out of 10, Exceptional, (53)
"Great overall stay"
The price is P5,288
P6,019 total
includes taxes & fees
Aug 24 - Aug 25
Tru By Hilton Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (124)
"The hotel was very clean and updated and the staff was super friendly and very informative!"
The price is P5,288
P5,966 total
includes taxes & fees
Aug 31 - Sep 1
Fairfield Inn & Suites by Marriott Cape Girardeau

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1006)
"We enjoyed the quick check in and how quiet the property was. "
The price is P3,995
P4,507 total
includes taxes & fees
Aug 18 - Aug 19
Pear Tree Inn Cape Girardeau West

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1001)
"The hotel was very nice and the staff were super helpful. I would stay here again!"
The price is P5,879
P6,632 total
includes taxes & fees
Sep 1 - Sep 2
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1006)
"Complimentary happy hour with appetizers was amazing! Great breakfast also."
The price is P5,136
P5,794 total
includes taxes & fees
Aug 21 - Aug 22
Drury Plaza Hotel Cape Girardeau Conference Center

Rockwood Inn

2.0 star property
10.0 out of 10, Exceptional, (16)
"The property was historic and renovations were perfect. Each room hads a bathroom, the beds were great. It was lovely and peaceful. "
The price is P8,578
P9,676 total
includes taxes & fees
Aug 24 - Aug 25
Rockwood Inn

Candlewood Suites Cape Girardeau by IHG

2.5 star property
8.0 out of 10, Very Good, (837)
"Great stay great staff"
The price is P4,224
P5,079 total
includes taxes & fees
Aug 26 - Aug 27
Candlewood Suites Cape Girardeau by IHG

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (436)
"Very clean and upscale hotel."
The price is P7,135
P8,085 total
includes taxes & fees
Aug 31 - Sep 1
Courtyard by Marriott Cape Girardeau Downtown

EC Reed's Mercantile and Hotel

3.0 star property
9.6 out of 10, Exceptional, (75)
"Great, clean room and the restaurant attached was delicious- best breakfast! "
EC Reed's Mercantile and Hotel

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (598)
"This was a great hotel at a great price!"
The price is P4,706
P5,093 total
includes taxes & fees
Aug 31 - Sep 1
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Makanda Inn

3.5 star property
10.0 out of 10, Exceptional, (33)
"Big thank you to the team at the cabin! Great people, great service, and great food! "
The price is P16,612
P18,937 total
includes taxes & fees
Aug 18 - Aug 19
Makanda Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Cape Girardeau

Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.

Photo by Skyy
Open Photo by Skyy

Best guest reviews of Cape Girardeau

Top Cape Girardeau Hotel Reviews

Frequently asked questions

What's the best place to stay in Cape Girardeau?

Tru By Hilton Cape Girardeau is a favorite property for Expedia customers. This hotel offers free breakfast and an indoor pool. Other favorite options based on traveler reviews include Fairfield Inn & Suites by Marriott Cape Girardeau and Courtyard by Marriott Cape Girardeau Downtown. See all available top hotels, or vacation rentals in Cape Girardeau.

If I need to cancel my hotel reservation in Cape Girardeau, will I receive a refund?

Yes, the majority of room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Cape Girardeau.

Where can I learn more about changing or cancelling my trip to Cape Girardeau?

For more details about picking new dates or cancelling your trip to Cape Girardeau, head over to our customer service page.

What's the best budget-friendly accommodation in Cape Girardeau?

Based on reviews, Pear Tree Inn Cape Girardeau Near the Medical Center is a popular hotel for our travelers in search of a less expensive place to stay and offers free WiFi. Another top option for your stay on the cheap is Pear Tree Inn Cape Girardeau West. View all budget hotels in Cape Girardeau.

What's the best hotel for families in Cape Girardeau?

Pear Tree Inn Cape Girardeau Near the Medical Center is a hotel with free WiFi and free cribs, and it's a top choice on Expedia for families. Other good choices to stay with the kids include Pear Tree Inn Cape Girardeau West and Drury Plaza Hotel Cape Girardeau Conference Center. Attractions like Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are also fun for kids of all ages. Find more child-friendly accommodations in Cape Girardeau.

What is the top LGBTQ-friendly place to stay in Cape Girardeau?

Pear Tree Inn Cape Girardeau Near the Medical Center is a top LGBTQ-friendly hotel, and features free WiFi and LCD TVs. Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West are two other good options for your trip. See all available hotels listed as LGBTQ-friendly in Cape Girardeau.

What's the best pet-friendly hotel in Cape Girardeau?

Pear Tree Inn Cape Girardeau Near the Medical Center is a top hotel for people traveling with their pets, and offers free WiFi for its human guests. Other good choices to stay with your pet include Tru By Hilton Cape Girardeau and Pear Tree Inn Cape Girardeau West. See more pet-friendly hotel accommodations in Cape Girardeau.

Where is the best hotel to stay with easy access to Southeast Missouri State University?

Courtyard by Marriott Cape Girardeau Downtown is one of the top choices for your stay based on our traveler data, and this 3-star hotel offers a restaurant and free parking. It's located just a short 0.8 mi (1.3 km) from Southeast Missouri State University. Other good choices within a few miles include Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West.

What about the best place to stay close to Show Me Center?

One of the top choices for your stay is Courtyard by Marriott Cape Girardeau Downtown, located a short 1 mi (1.6 km) from Show Me Center, and this 3-star hotel offers a restaurant and free parking. Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West are two other good options within a few miles.

What's the best accommodation in Cape Girardeau that's close to historical sites?

Based on our travel expertise, Pear Tree Inn Cape Girardeau Near the Medical Center is a top hotel on Expedia for those interested in history, and it features free breakfast and free WiFi.

What are some accommodations with pools in Cape Girardeau?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top hotel with a pool, a full-service spa, and free WiFi. View all hotels with pools in Cape Girardeau.

What is the best spa hotel in Cape Girardeau?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is a top spa hotel featuring a pool and a fitness center. See all spa hotels in Cape Girardeau.

What's the best place to stay near Cape Girardeau Municipal Airport (CGI)?

Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.

What is staying in Cape Girardeau like?

History buffs will enjoy exploring Cape Girardeau, and visitors give high marks for the top-notch restaurants. Tourists who journey to this welcoming city can discover its riverfront, university setting, and shopping. In Cape Girardeau, there are 49 hotels and other accommodations to choose from. Find out more about Cape Girardeau.

What are the top places to visit in Cape Girardeau?

Families come for attractions such as Cape Splash Family Aquatic Center, Cape Girardeau Conservation Nature Center, and Lazy L Safari Park. Landmarks like The Glenn House and Fort D Historic Site might be worth a visit. Natural beauty is on display at Shawnee National Forest, Mississippi River, and Cape Rock Park. Check out what more to see and do in Expedia's Cape Girardeau guide.

What's the weather like in Cape Girardeau?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Cape Girardeau is 59 inches.