Hotels in East Cape Girardeau from P4,227 for 2026 - Fully Refundable Options

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Our top choices for East Cape Girardeau hotels

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A hotel room with a bed, desk, chair, TV, and a small kitchenette area.

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

Rebecca

P6,235

P7,096 total

includes taxes & fees

Nov 19 - Nov 20

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

2. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Darnetta

P6,297

P7,104 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

A lobby with seating areas, a reception desk, and a bar.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

3. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

P7,879

P8,928 total

includes taxes & fees

Oct 28 - Oct 29

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

An outdoor patio with stone walls, wicker furniture, and large windows.

4. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Rebekah

P6,662

P7,516 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

5. The Riverview

Cape Girardeau

Scotty

P7,199

P8,121 total

includes taxes & fees

Oct 21 - Oct 22

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

6. Drury Inn & Suites Cape Girardeau

Cape Girardeau

DENNIS

P5,668

P6,394 total

includes taxes & fees

Oct 25 - Oct 26

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

7. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

P6,370

P7,187 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

8. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Troy

P4,534

P5,115 total

includes taxes & fees

Oct 25 - Oct 26

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

A hotel room with two beds, a nightstand, a lamp, and a chair.

9. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Elaine

P5,032

P5,446 total

includes taxes & fees

Nov 1 - Nov 2

A modern retail area with a display of local items and snacks.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

10. Tru By Hilton Cape Girardeau

Cape Girardeau

Shannon

P5,629

P6,407 total

includes taxes & fees

Oct 25 - Oct 26

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

A hotel room with a bed, a TV, a desk, and a chair.

11. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

Samuel

P4,786

P5,746 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

12. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

P4,764

P5,156 total

includes taxes & fees

Nov 8 - Nov 9

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

13. Quality Inn Cape Girardeau North

Cape Girardeau

Dayanita

P3,747

P4,227 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.

A bathroom with a marble wall and a white bathtub.

A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

14. Town House Inn Cape Giradreau

Cape Girardeau

Hope

P4,409

P5,150 total

includes taxes & fees

Oct 20 - Oct 21

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

15. Town House Inn

Jackson

Jennifer

P4,489

P4,858 total

includes taxes & fees

Oct 20 - Oct 21

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

A hotel room with two beds, a brick wall, and a wooden headboard.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

16. Drury Inn & Suites Jackson MO

Jackson

Lyn

P5,038

P5,326 total

includes taxes & fees

Nov 1 - Nov 2

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Top East Cape Girardeau Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"This hotel and staff was first class."

Town House Inn Cape Giradreau

8/10 Good

"Room was clean, bed was comfortable, staff was friendly, parking was easy. It was an older hotel and could use some renovation but would definitely stay again."

Tru By Hilton Cape Girardeau

10/10 Excellent

"A new property that is very clean and well trained staff"

Comfort Suites Jackson-Cape Girardeau

10/10 Excellent

"Overall very nice place clean excellent staff awesome breakfast and very good coffee bed very comfortable very nice updated rooms.. I plan on staying there again 😀"

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"I was surprised how reasonable the cost was considering how clean & nice all of the finishers were."

Drury Inn & Suites Jackson MO

10/10 Excellent

"Lovely hotel. Extremely happy with the accommodations. The hotel and room was very clean. The complimentary dinner was delicious. The pool area and workout room were clean and pleasant. Cute courtyard. Very happy with the service!"

Hampton Inn Cape Girardeau I 55 East

8/10 Good

"It was good. No complaints. The walls weren't terrible. No smells. It was clean & nice."

Pear Tree Inn Cape Girardeau West

10/10 Excellent

"We have stayed at the Pear Tree several times and never disappointed!! Great staff, clean rooms, generous breakfast. A special thanks to Lydia who took extra care to make our last stay remarkable. Thank you."

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent

"We have stayed here a number of times over 20 years. It’s always clean and well maintained. Breakfast is very good. Staff is always friendly and helpful."

More cheap stays in East Cape Girardeau

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO

P3,747

P4,227 total

Nov 1 - Nov 2

includes taxes & fees

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

P4,534

P5,115 total

Oct 25 - Oct 26

includes taxes & fees

9.2/10 Wonderful! (1,004 reviews)

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO

P4,786

P5,746 total

Oct 25 - Oct 26

includes taxes & fees

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

P5,629

P6,407 total

Oct 25 - Oct 26

includes taxes & fees

9.6/10 Exceptional! (195 reviews)

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

P6,235

P7,096 total

Nov 19 - Nov 20

includes taxes & fees

Hotel 7 Inn Anna

100 Richview Dr Anna IL

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Frequently asked questions

What's the best place to stay in East Cape Girardeau?

Located 4.6 mi (7.5 km) from the heart of East Cape Girardeau, Drury Plaza Hotel Cape Girardeau Conference Center is a top choice for your stay based on our traveler data. Two other options for your trip to the area are Pear Tree Inn Cape Girardeau West and The Riverview. See all available top hotels, or vacation rentals in East Cape Girardeau.

If I need to cancel my hotel reservation in East Cape Girardeau, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in East Cape Girardeau.

How is it staying in East Cape Girardeau?

Travelers to East Cape Girardeau will find plenty to explore and enjoy. There are 111 hotels and other accommodations in the surrounding area. Find out more about East Cape Girardeau.

What should I see while I'm in East Cape Girardeau?

Places to visit in the wider area include Century Casino & Hotel Cape Girardeau, Hunter Valley Winery, and eDen Spa & Salon. You'll also find Show Me Center and Cape Splash Family Aquatic Center in the area. Check out what more to see and do in Expedia's East Cape Girardeau guide.

What's the weather like in East Cape Girardeau?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for East Cape Girardeau is 59 inches.

East Cape Girardeau Hotels

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in East Cape Girardeau

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for East Cape Girardeau hotels

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2. Drury Plaza Hotel Cape Girardeau Conference Center

3. Courtyard by Marriott Cape Girardeau Downtown

4. Hampton Inn Cape Girardeau I 55 East

5. The Riverview

6. Drury Inn & Suites Cape Girardeau

7. Fairfield Inn & Suites by Marriott Cape Girardeau

8. Pear Tree Inn Cape Girardeau West

9. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10. Tru By Hilton Cape Girardeau

11. Candlewood Suites Cape Girardeau by IHG

12. Comfort Suites Jackson-Cape Girardeau

13. Quality Inn Cape Girardeau North

14. Town House Inn Cape Giradreau

15. Town House Inn

16. Drury Inn & Suites Jackson MO

Top East Cape Girardeau Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Town House Inn Cape Giradreau

Tru By Hilton Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

Courtyard by Marriott Cape Girardeau Downtown

Drury Inn & Suites Jackson MO

Hampton Inn Cape Girardeau I 55 East

Pear Tree Inn Cape Girardeau West

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

More cheap stays in East Cape Girardeau

Quality Inn Cape Girardeau North

Pear Tree Inn Cape Girardeau West

Candlewood Suites Cape Girardeau by IHG

Tru By Hilton Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel 7 Inn Anna

Frequently asked questions

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